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SKIL (Homo sapiens) in pLenti6.2/V5-DEST (V5-tagged lentiviral mammalian expression vector)

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Explanation of Terms


Gene: Gene Symbol:  SKIL
Gene Name:  SKI-like oncogene
Sequence             
Original Clone ID: FLH268417.01L
Keyword: None
Species: Homo sapiens
Type: cDNA
Vector Name: pLenti6.2/V5-DEST               Format:  FUSION
Source: HIP
Description: None
Comments: None
Mutation/
Discrepancy :
No / No
Publications: None
Authors:
HsCD00329527

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AVAILABLE
No restriction
Special MTA: None

 

Insert sequence: 2055nts         Open reading frame : 1 to 2055
Reference Sequence Alignment

ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGTAAATGGA
AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
GCCTTTGAAGTTGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
ACTGCTAAAGAATTG


Coding Sequence Details
Insert Sequence Verified?: N Verification Method: Insert was fully sequenced in parent vector
Reference Sequence Annotations:
End on reference sequence 2726
Start on reference sequence 672
Mutations:
None
Discrepancy:
None
5' Linker Sequence:
5p GTACAAAAAAGCAGGCTCCACC(atg-goi)

3' Linker Sequence:
5p (goi-stop)GACCCAGCTTTCTTGTAC

 

 Recommended Growth Condition:

Distributed in bacterial strain : DH5-alpha T1 phage resistant
Antibiotic Selection: Host Type:  bacterial    Marker:  ampicillin
Host Type:  mammalian    Marker:  blasticidin
Bacterial Selection Condition:  100 ug/mL ampicillin
Growth Condition:  Growth with the single antibiotic in LB at 37 degrees is recommended.
Comments:  Commonly used conditions for ampicillin resistant plasmid clones.
Protein Expression Results: None
Recommended expression in: Not Applicable
       DyNA Vector Map

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Vector Name: pLenti6.2/V5-DEST

pLenti6.2V5-DEST in advanced viewed

Synonyms: pLenti6.2/V5-DEST
Sequencing Primer: Forward:  CMV forward
Reverse:  V5 reverse
Description: Lentiviral mammalian expression vector;CMV promoter and C-terminal V5 tag; ampicillin resistance in bacteria; blasticidin resistance in mammalian cells; Gateway recombinational cloning.
Comments: None
Size (bp): 8813
Parent Vector: None
Empty Vector: None
Properties: Gateway, acceptor (destination), lentiviral infection, mammalian expression, recombinational cloning, with tag/fusion/marker
Author Name: Invitrogen
Publications: None
Vector Map:         Vector Sequence:
Sequence:

 



Vector Features:

Type Name Description Start Position End Position
bacterial origin pUC ori pUC origin of replication 7733 8406
death cassette ccdB ccdB death cassette (removed when insert is present) 3767 3976
packaging signal HIV-1 psi HIV-1 psi packaging signal 521 565
poly-A signal SV40 SV40 polyadenylation signal 5639 5770
promoter RSV RSV/5' LTR hybrid promoter 1 410
promoter CMV CMV promoter driving gene of interest 1809 2392
promoter PGK PGK promoter to drive selection marker in mammalian cells 4266 4771
recombination site attR2 attR2 recombinational cloning site 4127 4142
recombination site attR1 attR1 recombinational cloning site 2440 2456
response element HIV-1 RRE HIV-1 Rev response element (RRE) 1075 1308
selectable marker AmpR Ampicillin resistance gene for selection in bacteria 6728 7588
selectable marker BlastR Blasticidin resistance gene in mammalian cells 4849 5249
selectable marker CmR chloramphenicol resistance marker (removed in plasmids with insert) 2673 3329
splice acceptor site 3' splice acceptor two 3' splice acceptors at 1656 and 1684 1656 1656
splice donor site 5' splice donor 5' splice donor 520 520
tag V5 C-terminal V5 epitope tag 4197 4238

 

  • Gene
  • Pathways
  • Protein
  • Clone
  • Organism
  • Genome
  • Reagents

Gene

 

Gene Symbol : SKIL
Symbol Nomenclature : SKIL
SYNONYM : SNO; SnoA; SnoI; SnoN
Designation : ski-like protein|ski-related oncogene snoN
Full Nomenclature : SKI-like oncogene
GENEID : 6498
HGNC : 10897
MIM : 165340
Vega : OTTHUMG00000158831
Target GenBank: BC059386

 

Reference Sequence Alignment

  

HsCD00329527        ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
NM_005414.4         ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
XM_005247721.1      ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
NM_001145098.2      ------------------------------------------------------------
NM_001248008.1      ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
NM_001145097.2      ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
                                                                                

HsCD00329527        ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGTAAATGGA
NM_005414.4         ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
XM_005247721.1      ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
NM_001145098.2      ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
NM_001248008.1      ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
NM_001145097.2      ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
                    **************************************************** *******

HsCD00329527        AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
NM_005414.4         AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
XM_005247721.1      AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
NM_001145098.2      AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
NM_001248008.1      AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
NM_001145097.2      AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
                    ************************************************************

HsCD00329527        CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
NM_005414.4         CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
XM_005247721.1      CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
NM_001145098.2      CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
NM_001248008.1      CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
NM_001145097.2      CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
                    ************************************************************

HsCD00329527        CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
NM_005414.4         CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
XM_005247721.1      CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
NM_001145098.2      CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
NM_001248008.1      CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
NM_001145097.2      CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
                    ************************************************************

HsCD00329527        CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
NM_005414.4         CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
XM_005247721.1      CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
NM_001145098.2      CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
NM_001248008.1      CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
NM_001145097.2      CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
                    ************************************************************

HsCD00329527        TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
NM_005414.4         TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
XM_005247721.1      TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
NM_001145098.2      TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
NM_001248008.1      TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
NM_001145097.2      TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
                    ************************************************************

HsCD00329527        TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
NM_005414.4         TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
XM_005247721.1      TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
NM_001145098.2      TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
NM_001248008.1      TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
NM_001145097.2      TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
                    ************************************************************

HsCD00329527        GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
NM_005414.4         GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
XM_005247721.1      GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
NM_001145098.2      GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
NM_001248008.1      GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
NM_001145097.2      GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
                    ************************************************************

HsCD00329527        CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
NM_005414.4         CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
XM_005247721.1      CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
NM_001145098.2      CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
NM_001248008.1      CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
NM_001145097.2      CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
                    ************************************************************

HsCD00329527        CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
NM_005414.4         CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
XM_005247721.1      CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
NM_001145098.2      CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
NM_001248008.1      CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
NM_001145097.2      CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
                    ************************************************************

HsCD00329527        ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
NM_005414.4         ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
XM_005247721.1      ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
NM_001145098.2      ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
NM_001248008.1      ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
NM_001145097.2      ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
                    ************************************************************

HsCD00329527        CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
NM_005414.4         CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
XM_005247721.1      CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
NM_001145098.2      CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
NM_001248008.1      CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
NM_001145097.2      CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
                    ************************************************************

HsCD00329527        GCCTTTGAAGTTGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
NM_005414.4         GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
XM_005247721.1      GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
NM_001145098.2      GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
NM_001248008.1      GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
NM_001145097.2      GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
                    *********** ************************************************

HsCD00329527        TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
NM_005414.4         TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
XM_005247721.1      TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
NM_001145098.2      TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
NM_001248008.1      TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
NM_001145097.2      TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
                    ************************************************************

HsCD00329527        CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
NM_005414.4         CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
XM_005247721.1      CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
NM_001145098.2      CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
NM_001248008.1      CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
NM_001145097.2      CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
                    ************************************************************

HsCD00329527        GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
NM_005414.4         GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
XM_005247721.1      GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
NM_001145098.2      GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
NM_001248008.1      GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
NM_001145097.2      GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
                    ************************************************************

HsCD00329527        GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
NM_005414.4         GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
XM_005247721.1      GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
NM_001145098.2      GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
NM_001248008.1      GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
NM_001145097.2      GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
                    ************************************************************

HsCD00329527        AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
NM_005414.4         AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
XM_005247721.1      AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
NM_001145098.2      AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
NM_001248008.1      AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
NM_001145097.2      AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
                    ************************************************************

HsCD00329527        GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
NM_005414.4         GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
XM_005247721.1      GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
NM_001145098.2      GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
NM_001248008.1      GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
NM_001145097.2      GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
                    ************************************************************

HsCD00329527        TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
NM_005414.4         TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
XM_005247721.1      TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
NM_001145098.2      TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
NM_001248008.1      TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
NM_001145097.2      TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
                    ************************************************************

HsCD00329527        CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
NM_005414.4         CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
XM_005247721.1      CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
NM_001145098.2      CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
NM_001248008.1      CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
NM_001145097.2      CAGTCTAAAGAGCTCACAAAGACAGAG---------------------------------
                    ***************************                                 

HsCD00329527        GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
NM_005414.4         GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
XM_005247721.1      GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
NM_001145098.2      GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
NM_001248008.1      GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
NM_001145097.2      ------------------------------------------------------------
                                                                                

HsCD00329527        CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
NM_005414.4         CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
XM_005247721.1      CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
NM_001145098.2      CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
NM_001248008.1      CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
NM_001145097.2      ---------------------------------------------GCAAATGCATCAATC
                                                                   *.***********

HsCD00329527        TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
NM_005414.4         TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
XM_005247721.1      TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
NM_001145098.2      TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
NM_001248008.1      TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
NM_001145097.2      TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
                    ************************************************************

HsCD00329527        ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
NM_005414.4         ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
XM_005247721.1      ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
NM_001145098.2      ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
NM_001248008.1      ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
NM_001145097.2      ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
                    ************************************************************

HsCD00329527        GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
NM_005414.4         GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
XM_005247721.1      GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
NM_001145098.2      GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
NM_001248008.1      GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
NM_001145097.2      GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
                    ************************************************************

HsCD00329527        CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
NM_005414.4         CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
XM_005247721.1      CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
NM_001145098.2      CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
NM_001248008.1      CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
NM_001145097.2      CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
                    ************************************************************

HsCD00329527        ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
NM_005414.4         ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
XM_005247721.1      ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
NM_001145098.2      ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
NM_001248008.1      ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
NM_001145097.2      ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
                    ************************************************************

HsCD00329527        GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
NM_005414.4         GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
XM_005247721.1      GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
NM_001145098.2      GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
NM_001248008.1      GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
NM_001145097.2      GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
                    ************************************************************

HsCD00329527        AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
NM_005414.4         AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
XM_005247721.1      AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
NM_001145098.2      AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
NM_001248008.1      AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
NM_001145097.2      AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
                    ************************************************************

HsCD00329527        TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
NM_005414.4         TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
XM_005247721.1      TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
NM_001145098.2      TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
NM_001248008.1      TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
NM_001145097.2      TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
                    ************************************************************

HsCD00329527        GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
NM_005414.4         GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
XM_005247721.1      GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
NM_001145098.2      GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
NM_001248008.1      GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
NM_001145097.2      GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
                    ************************************************************

HsCD00329527        AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
NM_005414.4         AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
XM_005247721.1      AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
NM_001145098.2      AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
NM_001248008.1      AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
NM_001145097.2      AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
                    ************************************************************

HsCD00329527        ACTGCTAAAGAATTG
NM_005414.4         ACTGCTAAAGAATAG
XM_005247721.1      ACTGCTAAAGAATAG
NM_001145098.2      ACTGCTAAAGAATAG
NM_001248008.1      ACTGCTAAAGAATAG
NM_001145097.2      ACTGCTAAAGAATAG
                    *************:*

Pathways

NCI : Regulation of nuclear SMAD2/3 signaling
NCI : TGF-beta receptor signaling
Panther : Gonadotropin-releasing hormone receptor pathway
Panther : TGF-beta signaling pathway
Reactome : Disease
Reactome : Downregulation of SMAD2/3:SMAD4 transcriptional activity
Reactome : Gene Expression
Reactome : Generic Transcription Pathway
Reactome : Loss of Function of SMAD2/3 in Cancer
Reactome : Loss of Function of SMAD4 in Cancer
Reactome : Loss of Function of TGFBR1 in Cancer
Reactome : Loss of Function of TGFBR2 in Cancer
Reactome : SMAD2/3 MH2 Domain Mutants in Cancer
Reactome : SMAD2/3 Phosphorylation Motif Mutants in Cancer
Reactome : SMAD4 MH2 Domain Mutants in Cancer
Reactome : Signal Transduction
Reactome : Signaling by TGF-beta Receptor Complex
Reactome : Signaling by TGF-beta Receptor Complex in Cancer
Reactome : TGFBR1 KD Mutants in Cancer
Reactome : TGFBR1 LBD Mutants in Cancer
Reactome : TGFBR2 Kinase Domain Mutants in Cancer
Reactome : TGFBR2 MSI Frameshift Mutants in Cancer
Reactome : Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
WikiPathway : TGF Beta Signaling Pathway
WikiPathway : TGF beta Signaling Pathway

Protein

SMART domain : c-SKI_SMAD_bind : c-SKI Smad4 binding domain
UniProt : P12757
HPRD : 01319

Clone

Cloning Information : 268417
HIP Master Clone ID : 194922
Original Clone ID : FLH268417.01L

Organism


TAX_ID : 9606
Species Specific ID: 6498

Genome

Chromosome : 3
Map Location : 3q26
Ensembl : ENSG00000136603

Reagents

Labome : SnoN-antibody