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ORC3L (Homo sapiens) in pLenti6.2/V5-DEST (V5-tagged lentiviral mammalian expression vector)

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Explanation of Terms


Gene: Gene Symbol:  ORC3
Gene Name:  origin recognition complex, subunit 3
Sequence             
Original Clone ID: FLH268421.01L
Keyword: None
Species: Homo sapiens
Type: cDNA
Vector Name: pLenti6.2/V5-DEST               Format:  FUSION
Source: HIP
Description: None
Comments: None
Mutation/
Discrepancy :
No / No
Publications: None
Authors:
HsCD00329531

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AVAILABLE
No restriction
Special MTA: None

 

Insert sequence: 2136nts         Open reading frame : 1 to 2136
Reference Sequence Alignment

ATGGCTACGTCCTCGATGTCTAAGGGTTGCTTTGTTTTTAAGCCAAACTCCAAAAAGAGA
AAGATCTCTCTGCCAATAGAGGACTATTTTAACAAAGGGAAAAATGAGCCTGAGGACAGT
AAGCTTCGATTCGAAACTTATCAGTTGATATGGCAGCAGATGAAATCTGAAAATGAGCGA
CTACAAGAGGAATTAAATAAAAACTTGTTTGACAATCTGATTGAATTTCTGCAAAAATCA
CATTCTGGATTCCAGAAGAATTCAAGAGACTTGGGCGGTCAAATAAAACTCAGAGAAATT
CCAACTGCTGCTCTTGTTCTTGGTGTGAATGTCACAGATCATGATTTGACATTCGGAAGT
CTAACAGAGGCCCTTCAGAATAATGTCACACCATATGTAGTCTCATTGCAAGCTAAAGAT
TGTCCAGATATGAAACATTTTTTGCAAAAGTTGATCTCACAGTTGATGGACTGCTGTGTA
GATATAAAATCCAAAGAGGAGGAAAGTGTTCACGTCACCCAAAGAAAGACACATTATTCA
ATGGATTCACTTTCCAGTTGGTATATGACTGTCACACAGAAGACGGACCCAAAAATGCTA
AGCAAAAAAAGGACTACTTCTAGCCAATGGCAGTCTCCTCCTGTTGTCGTTATCTTGAAG
GATATGGAAAGCTTTGCCACAAAAGTACTACAAGACTTCATAATTATCAGCAGTCAACAT
CTCCATGAATTTCCACTAATACTCATTTTTGGAATAGCCACATCTCCTATTATCATCCAC
CGATTGCTTCCTCATGCAGTATCATCTCTATTGTGCATAGAACTGTTCCAATCTTTGTCT
TGTAAGGAGCACCTGACTACGGTACTCGATAAGCTACTTCTTACAACTCAGTTTCCCTTT
AAAATAAATGAAAAAGTATTACAGGTTCTGACCAACATCTTTTTGTATCATGATTTCTCA
GTTCAAAACTTTATAAAAGGACTTCAGCTTTCTCTATTAGAGCATTTCTATTCCCAGCCC
TTAAGTGTCCTGTGCTGTAATCTTCCAGAAGCCAAAAGAAGAATAAATTTTTTATCAAAT
AATCAATGTGAAAACATCCGACGTCTACCATCTTTTAGGAGGTACGTGGAAAAGCAAGCT
TCAGAAAAGCAAGTTGCGCTCTTGACCAATGAGAGATATTTGAAGGAGGAAACACAATTA
TTACTAGAAAACCTGCATGTTTATCATATGAATTACTTCCTGGTTTTGAGATGTCTTCAT
AAGTTCACCTCTTCTCTTCCCAAGTATCCACTAGGTCGACAGATCAGAGAGTTGTACTGT
ACATGTTTAGAAAAGAACATATGGGATTCAGAGGAGTATGCATCAGTCTTGCAGCTGCTG
AGGATGTTGGCAAAGGATGAACTGATGACCATACTTGAGAAATGTTTCAAGGTTTTTAAG
TCTTATTGTGAAAACCACCTTGGCAGCACAGCTAAGAGAATAGAGGAGTTCCTGGCCCAG
TTTCAGAGCCTCGATGAAACCAAAGAGGAAGAAGATGCTTCTGGGTCACAGCCAAAGGGG
CTTCAGAAGACAGACCTCTATCATCTTCAGAAGTCCTTATTGGAAATGAAGGAGTTAAGA
AGAAGTAAGAAGCAAACCAAATTTGAAGTACTCAGAGAAAATGTTGTGAACTTCATTGAC
TGTCTAGTGAGAGAATACCTTCTGCCTCCTGAGACACAGCCTCTCCATGAGGTGGTGTAC
TTCAGTGCTGCCCATGCCCTTCGTGAGCATTTAAATGCTGCTCCGCGAATTGCCCTCCAT
ACTGCACTCAACAATCCTTACTATTATCTCAAGAATGAAGCACTGAAAAGCGAAGAAGGC
TGCATTCCGAATATCGCCCCAGACATCTGCATAGCATACAAACTGCACCTAGAGTGTAGC
AGGCTCATCAACCTCGTGGACTGGTCAGAGGCTTTTGCAACAGTTGTGACAGCTGCTGAA
AAAATGGATGCAAATTCTGCAACCTCAGAAGAAATGAATGAAATTATCCATGCTCGGTTT
ATTAGAGCTGTTTCTGAACTAGAACTTTTAGGATTTATAAAACCTACCAAACAGAAGACT
GACCATGTGGCAAGACTAACATGGGGAGGCTGCTTG


Coding Sequence Details
Insert Sequence Verified?: N Verification Method: Insert was fully sequenced in parent vector
Reference Sequence Annotations:
End on reference sequence 2153
Start on reference sequence 18
Mutations:
None
Discrepancy:
None
5' Linker Sequence:
5p GTACAAAAAAGCAGGCTCCACC(atg-goi)

3' Linker Sequence:
5p (goi-stop)GACCCAGCTTTCTTGTAC

 

 Recommended Growth Condition:

Distributed in bacterial strain : DH5-alpha T1 phage resistant
Antibiotic Selection: Host Type:  bacterial    Marker:  ampicillin
Host Type:  mammalian    Marker:  blasticidin
Bacterial Selection Condition:  100 ug/mL ampicillin
Growth Condition:  Growth with the single antibiotic in LB at 37 degrees is recommended.
Comments:  Commonly used conditions for ampicillin resistant plasmid clones.
Protein Expression Results: None
Recommended expression in: Not Applicable
       DyNA Vector Map

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Vector Name: pLenti6.2/V5-DEST

pLenti6.2V5-DEST in advanced viewed

Synonyms: pLenti6.2/V5-DEST
Sequencing Primer: Forward:  CMV forward
Reverse:  V5 reverse
Description: Lentiviral mammalian expression vector;CMV promoter and C-terminal V5 tag; ampicillin resistance in bacteria; blasticidin resistance in mammalian cells; Gateway recombinational cloning.
Comments: None
Size (bp): 8813
Parent Vector: None
Empty Vector: None
Properties: Gateway, acceptor (destination), lentiviral infection, mammalian expression, recombinational cloning, with tag/fusion/marker
Author Name: Invitrogen
Publications: None
Vector Map:         Vector Sequence:
Sequence:

 



Vector Features:

Type Name Description Start Position End Position
bacterial origin pUC ori pUC origin of replication 7733 8406
death cassette ccdB ccdB death cassette (removed when insert is present) 3767 3976
packaging signal HIV-1 psi HIV-1 psi packaging signal 521 565
poly-A signal SV40 SV40 polyadenylation signal 5639 5770
promoter RSV RSV/5' LTR hybrid promoter 1 410
promoter CMV CMV promoter driving gene of interest 1809 2392
promoter PGK PGK promoter to drive selection marker in mammalian cells 4266 4771
recombination site attR2 attR2 recombinational cloning site 4127 4142
recombination site attR1 attR1 recombinational cloning site 2440 2456
response element HIV-1 RRE HIV-1 Rev response element (RRE) 1075 1308
selectable marker AmpR Ampicillin resistance gene for selection in bacteria 6728 7588
selectable marker BlastR Blasticidin resistance gene in mammalian cells 4849 5249
selectable marker CmR chloramphenicol resistance marker (removed in plasmids with insert) 2673 3329
splice acceptor site 3' splice acceptor two 3' splice acceptors at 1656 and 1684 1656 1656
splice donor site 5' splice donor 5' splice donor 520 520
tag V5 C-terminal V5 epitope tag 4197 4238

 

  • Gene
  • Pathways
  • Protein
  • Clone
  • Organism
  • Genome
  • Reagents

Gene

 

Gene Symbol : ORC3
Symbol Nomenclature : ORC3
SYNONYM : LAT; LATHEO; ORC3L
Designation : homolog of latheo, Drosophila|origin recognition complex subunit 3|origin recognition complex subunit Latheo|origin recognition complex, subunit 3 honolog
Full Nomenclature : origin recognition complex, subunit 3
GENEID : 23595
Locus Tag : RP3-486L4.1
HGNC : 8489
MIM : 604972
Vega : OTTHUMG00000015179
Target GenBank: BC035494

 

Reference Sequence Alignment

  

HsCD00329531        ATGGCTACGTCCTCGATGTCTAAGGGTTGCTTTGTTTTTAAGCCAAACTCCAAAAAGAGA
XM_005248704.1      ATGGCTACGTCCTCGATGTCTAAGGGTTGCTTTGTTTTTAAGCCAAACTCCAAAAAGAGA
NM_181837.2         ATGGCTACGTCCTCGATGTCTAAGGGTTGCTTTGTTTTTAAGCCAAACTCCAAAAAGAGA
XM_005248705.1      ------------------------------------------------------------
NM_012381.3         ATGGCTACGTCCTCGATGTCTAAGGGTTGCTTTGTTTTTAAGCCAAACTCCAAAAAGAGA
XM_005248706.1      ------------------------------------------------------------
                                                                                

HsCD00329531        AAGATCTCTCTGCCAATAGAGGACTATTTTAACAAAGGGAAAAATGAGCCTGAGGACAGT
XM_005248704.1      AAGATCTCTCTGCCAATAGAGGACTATTTTAACAAAGGGAAAAATGAGCCTGAGGACAGT
NM_181837.2         AAGATCTCTCTGCCAATAGAGGACTATTTTAACAAAGGGAAAAATGAGCCTGAGGACAGT
XM_005248705.1      ------------------------------------------------------------
NM_012381.3         AAGATCTCTCTGCCAATAGAGGACTATTTTAACAAAGGGAAAAATGAGCCTGAGGACAGT
XM_005248706.1      ------------------------------------------------------------
                                                                                

HsCD00329531        AAGCTTCGATTCGAAACTTATCAGTTGATATGGCAGCAGATGAAATCTGAAAATGAGCGA
XM_005248704.1      AAGCTTCGATTCGAAACTTATCAGTTGATATGGCAGCAGATGAAATCTGAAAATGAGCGA
NM_181837.2         AAGCTTCGATTCGAAACTTATCAGTTGATATGGCAGCAGATGAAATCTGAAAATGAGCGA
XM_005248705.1      ---------------------------------------ATGAAATCTGAAAATGAGCGA
NM_012381.3         AAGCTTCGATTCGAAACTTATCAGTTGATATGGCAGCAGATGAAATCTGAAAATGAGCGA
XM_005248706.1      ---------------------------------------ATGAAATCTGAAAATGAGCGA
                                                           *********************

HsCD00329531        CTACAAGAGGAATTAAATAAAAACTTGTTTGACAATCTGATTGAATTTCTGCAAAAATCA
XM_005248704.1      CTACAAGAGGAATTAAATAAAAACTTGTTTGACAATCTGATTGAATTTCTGCAAAAATCA
NM_181837.2         CTACAAGAGGAATTAAATAAAAACTTGTTTGACAATCTGATTGAATTTCTGCAAAAATCA
XM_005248705.1      CTACAAGAGGAATTAAATAAAAACTTGTTTGACAATCTGATTGAATTTCTGCAAAAATCA
NM_012381.3         CTACAAGAGGAATTAAATAAAAACTTGTTTGACAATCTGATTGAATTTCTGCAAAAATCA
XM_005248706.1      CTACAAGAGGAATTAAATAAAAACTTGTTTGACAATCTGATTGAATTTCTGCAAAAATCA
                    ************************************************************

HsCD00329531        CATTCTGGATTCCAGAAGAATTCAAGAGACTTGGGCGGTCAAATAAAACTCAGAGAAATT
XM_005248704.1      CATTCTGGATTCCAGAAGAATTCAAGAGACTTGGGCGGTCAAATAAAACTCAGAGAAATT
NM_181837.2         CATTCTGGATTCCAGAAGAATTCAAGAGACTTGGGCGGTCAAATAAAACTCAGAGAAATT
XM_005248705.1      CATTCTGGATTCCAGAAGAATTCAAGAGACTTGGGCGGTCAAATAAAACTCAGAGAAATT
NM_012381.3         CATTCTGGATTCCAGAAGAATTCAAGAGACTTGGGCGGTCAAATAAAACTCAGAGAAATT
XM_005248706.1      CATTCTGGATTCCAGAAGAATTCAAGAGACTTGGGCGGTCAAATAAAACTCAGAGAAATT
                    ************************************************************

HsCD00329531        CCAACTGCTGCTCTTGTTCTTGGTGTGAATGTCACAGATCATGATTTGACATTCGGAAGT
XM_005248704.1      CCAACTGCTGCTCTTGTTCTTGGTGTGAATGTCACAGATCATGATTTGACATTCGGAAGT
NM_181837.2         CCAACTGCTGCTCTTGTTCTTGGTGTGAATGTCACAGATCATGATTTGACATTCGGAAGT
XM_005248705.1      CCAACTGCTGCTCTTGTTCTTGGTGTGAATGTCACAGATCATGATTTGACATTCGGAAGT
NM_012381.3         CCAACTGCTGCTCTTGTTCTTGGTGTGAATGTCACAGATCATGATTTGACATTCGGAAGT
XM_005248706.1      CCAACTGCTGCTCTTGTTCTTGGTGTGAATGTCACAGATCATGATTTGACATTCGGAAGT
                    ************************************************************

HsCD00329531        CTAACAGAGGCCCTTCAGAATAATGTCACACCATATGTAGTCTCATTGCAAGCTAAAGAT
XM_005248704.1      CTAACAGAGGCCCTTCAGAATAATGTCACACCATATGTAGTCTCATTGCAAGCTAAAGAT
NM_181837.2         CTAACAGAGGCCCTTCAGAATAATGTCACACCATATGTAGTCTCATTGCAAGCTAAAGAT
XM_005248705.1      CTAACAGAGGCCCTTCAGAATAATGTCACACCATATGTAGTCTCATTGCAAGCTAAAGAT
NM_012381.3         CTAACAGAGGCCCTTCAGAATAATGTCACACCATATGTAGTCTCATTGCAAGCTAAAGAT
XM_005248706.1      CTAACAGAGGCCCTTCAGAATAATGTCACACCATATGTAGTCTCATTGCAAGCTAAAGAT
                    ************************************************************

HsCD00329531        TGTCCAGATATGAAACATTTTTTGCAAAAGTTGATCTCACAGTTGATGGACTGCTGTGTA
XM_005248704.1      TGTCCAGATATGAAACATTTTTTGCAAAAGTTGATCTCACAGTTGATGGACTGCTGTGTA
NM_181837.2         TGTCCAGATATGAAACATTTTTTGCAAAAGTTGATCTCACAGTTGATGGACTGCTGTGTA
XM_005248705.1      TGTCCAGATATGAAACATTTTTTGCAAAAGTTGATCTCACAGTTGATGGACTGCTGTGTA
NM_012381.3         TGTCCAGATATGAAACATTTTTTGCAAAAGTTGATCTCACAGTTGATGGACTGCTGTGTA
XM_005248706.1      TGTCCAGATATGAAACATTTTTTGCAAAAGTTGATCTCACAGTTGATGGACTGCTGTGTA
                    ************************************************************

HsCD00329531        GATATAAAATCCAAAGAGGAGGAAAGTGTTCACGTCACCCAAAGAAAGACACATTATTCA
XM_005248704.1      GATATAAAATCCAAAGAGGAGGAAAGTGTTCACGTCACCCAAAGAAAGACACATTATTCA
NM_181837.2         GATATAAAATCCAAAGAGGAGGAAAGTGTTCACGTCACCCAAAGAAAGACACATTATTCA
XM_005248705.1      GATATAAAATCCAAAGAGGAGGAAAGTGTTCACGTCACCCAAAGAAAGACACATTATTCA
NM_012381.3         GATATAAAATCCAAAGAGGAGGAAAGTGTTCACGTCACCCAAAGAAAGACACATTATTCA
XM_005248706.1      GATATAAAATCCAAAGAGGAGGAAAGTGTTCACGTCACCCAAAGAAAGACACATTATTCA
                    ************************************************************

HsCD00329531        ATGGATTCACTTTCCAGTTGGTATATGACTGTCACACAGAAGACGGACCCAAAAATGCTA
XM_005248704.1      ATGGATTCACTTTCCAGTTGGTATATGACTGTCACACAGAAGACGGACCCAAAAATGCTA
NM_181837.2         ATGGATTCACTTTCCAGTTGGTATATGACTGTCACACAGAAGACGGACCCAAAAATGCTA
XM_005248705.1      ATGGATTCACTTTCCAGTTGGTATATGACTGTCACACAGAAGACGGACCCAAAAATGCTA
NM_012381.3         ATGGATTCACTTTCCAGTTGGTATATGACTGTCACACAGAAGACGGACCCAAAAATGCTA
XM_005248706.1      ATGGATTCACTTTCCAGTTGGTATATGACTGTCACACAGAAGACGGACCCAAAAATGCTA
                    ************************************************************

HsCD00329531        AGCAAAAAAAGGACTACTTCTAGCCAATGGCAGTCTCCTCCTGTTGTCGTTATCTTGAAG
XM_005248704.1      AGCAAAAAAAGGACTACTTCTAGCCAATGGCAGTCTCCTCCTGTTGTCGTTATCTTGAAG
NM_181837.2         AGCAAAAAAAGGACTACTTCTAGCCAATGGCAGTCTCCTCCTGTTGTCGTTATCTTGAAG
XM_005248705.1      AGCAAAAAAAGGACTACTTCTAGCCAATGGCAGTCTCCTCCTGTTGTCGTTATCTTGAAG
NM_012381.3         AGCAAAAAAAGGACTACTTCTAGCCAATGGCAGTCTCCTCCTGTTGTCGTTATCTTGAAG
XM_005248706.1      AGCAAAAAAAGGACTACTTCTAGCCAATGGCAGTCTCCTCCTGTTGTCGTTATCTTGAAG
                    ************************************************************

HsCD00329531        GATATGGAAAGCTTTGCCACAAAAGTACTACAAGACTTCATAATTATCAGCAGTCAACAT
XM_005248704.1      GATATGGAAAGCTTTGCCACAAAAGTACTACAAGACTTCATAATTATCAGCAGTCAACAT
NM_181837.2         GATATGGAAAGCTTTGCCACAAAAGTACTACAAGACTTCATAATTATCAGCAGTCAACAT
XM_005248705.1      GATATGGAAAGCTTTGCCACAAAAGTACTACAAGACTTCATAATTATCAGCAGTCAACAT
NM_012381.3         GATATGGAAAGCTTTGCCACAAAAGTACTACAAGACTTCATAATTATCAGCAGTCAACAT
XM_005248706.1      GATATGGAAAGCTTTGCCACAAAAGTACTACAAGACTTCATAATTATCAGCAGTCAACAT
                    ************************************************************

HsCD00329531        CTCCATGAATTTCCACTAATACTCATTTTTGGAATAGCCACATCTCCTATTATCATCCAC
XM_005248704.1      CTCCATGAATTTCCACTAATACTCATTTTTGGAATAGCCACATCTCCTATTATCATCCAC
NM_181837.2         CTCCATGAATTTCCACTAATACTCATTTTTGGAATAGCCACATCTCCTATTATCATCCAC
XM_005248705.1      CTCCATGAATTTCCACTAATACTCATTTTTGGAATAGCCACATCTCCTATTATCATCCAC
NM_012381.3         CTCCATGAATTTCCACTAATACTCATTTTTGGAATAGCCACATCTCCTATTATCATCCAC
XM_005248706.1      CTCCATGAATTTCCACTAATACTCATTTTTGGAATAGCCACATCTCCTATTATCATCCAC
                    ************************************************************

HsCD00329531        CGATTGCTTCCTCATGCAGTATCATCTCTATTGTGCATAGAACTGTTCCAATCTTTGTCT
XM_005248704.1      CGATTGCTTCCTCATGCAGTATCATCTCTATTGTGCATAGAACTGTTCCAATCTTTGTCT
NM_181837.2         CGATTGCTTCCTCATGCAGTATCATCTCTATTGTGCATAGAACTGTTCCAATCTTTGTCT
XM_005248705.1      CGATTGCTTCCTCATGCAGTATCATCTCTATTGTGCATAGAACTGTTCCAATCTTTGTCT
NM_012381.3         CGATTGCTTCCTCATGCAGTATCATCTCTATTGTGCATAGAACTGTTCCAATCTTTGTCT
XM_005248706.1      CGATTGCTTCCTCATGCAGTATCATCTCTATTGTGCATAGAACTGTTCCAATCTTTGTCT
                    ************************************************************

HsCD00329531        TGTAAGGAGCACCTGACTACGGTACTCGATAAGCTACTTCTTACAACTCAGTTTCCCTTT
XM_005248704.1      TGTAAGGAGCACCTGACTACGGTACTCGATAAGCTACTTCTTACAACTCAGTTTCCCTTT
NM_181837.2         TGTAAGGAGCACCTGACTACGGTACTCGATAAGCTACTTCTTACAACTCAGTTTCCCTTT
XM_005248705.1      TGTAAGGAGCACCTGACTACGGTACTCGATAAGCTACTTCTTACAACTCAGTTTCCCTTT
NM_012381.3         TGTAAGGAGCACCTGACTACGGTACTCGATAAGCTACTTCTTACAACTCAGTTTCCCTTT
XM_005248706.1      TGTAAGGAGCACCTGACTACGGTACTCGATAAGCTACTTCTTACAACTCAGTTTCCCTTT
                    ************************************************************

HsCD00329531        AAAATAAATGAAAAAGTATTACAGGTTCTGACCAACATCTTTTTGTATCATGATTTCTCA
XM_005248704.1      AAAATAAATGAAAAAGTATTACAGGTTCTGACCAACATCTTTTTGTATCATGATTTCTCA
NM_181837.2         AAAATAAATGAAAAAGTATTACAGGTTCTGACCAACATCTTTTTGTATCATGATTTCTCA
XM_005248705.1      AAAATAAATGAAAAAGTATTACAGGTTCTGACCAACATCTTTTTGTATCATGATTTCTCA
NM_012381.3         AAAATAAATGAAAAAGTATTACAGGTTCTGACCAACATCTTTTTGTATCATGATTTCTCA
XM_005248706.1      AAAATAAATGAAAAAGTATTACAGGTTCTGACCAACATCTTTTTGTATCATGATTTCTCA
                    ************************************************************

HsCD00329531        GTTCAAAACTTTATAAAAGGACTTCAGCTTTCTCTATTAGAGCATTTCTATTCCCAGCCC
XM_005248704.1      GTTCAAAACTTTATAAAAGGACTTCAGCTTTCTCTATTAGAGCATTTCTATTCCCAGCCC
NM_181837.2         GTTCAAAACTTTATAAAAGGACTTCAGCTTTCTCTATTAGAGCATTTCTATTCCCAGCCC
XM_005248705.1      GTTCAAAACTTTATAAAAGGACTTCAGCTTTCTCTATTAGAGCATTTCTATTCCCAGCCC
NM_012381.3         GTTCAAAACTTTATAAAAGGACTTCAGCTTTCTCTATTAGAGCATTTCTATTCCCAGCCC
XM_005248706.1      GTTCAAAACTTTATAAAAGGACTTCAGCTTTCTCTATTAGAGCATTTCTATTCCCAGCCC
                    ************************************************************

HsCD00329531        TTAAGTGTCCTGTGCTGTAATCTTCCAGAAGCCAAAAGAAGAATAAATTTTTTATCAAAT
XM_005248704.1      TTAAGTGTCCTGTGCTGTAATCTTCCAGAAGCCAAAAGAAGAATAAATTTTTTATCAAAT
NM_181837.2         TTAAGTGTCCTGTGCTGTAATCTTCCAGAAGCCAAAAGAAGAATAAATTTTTTATCAAAT
XM_005248705.1      TTAAGTGTCCTGTGCTGTAATCTTCCAGAAGCCAAAAGAAGAATAAATTTTTTATCAAAT
NM_012381.3         TTAAGTGTCCTGTGCTGTAATCTTCCAGAAGCCAAAAGAAGAATAAATTTTTTATCAAAT
XM_005248706.1      TTAAGTGTCCTGTGCTGTAATCTTCCAGAAGCCAAAAGAAGAATAAATTTTTTATCAAAT
                    ************************************************************

HsCD00329531        AATCAATGTGAAAACATCCGACGTCTACCATCTTTTAGGAGGTACGTGGAAAAGCAAGCT
XM_005248704.1      AATCAATGTGAAAACATCCGACGTCTACCATCTTTTAGGAGGTACGTGGAAAAGCAAGCT
NM_181837.2         AATCAATGTGAAAACATCCGACGTCTACCATCTTTTAGGAGGTACGTGGAAAAGCAAGCT
XM_005248705.1      AATCAATGTGAAAACATCCGACGTCTACCATCTTTTAGGAGGTACGTGGAAAAGCAAGCT
NM_012381.3         AATCAATGTGAAAACATCCGACGTCTACCATCTTTTAGGAGGTACGTGGAAAAGCAAGCT
XM_005248706.1      AATCAATGTGAAAACATCCGACGTCTACCATCTTTTAGGAGGTACGTGGAAAAGCAAGCT
                    ************************************************************

HsCD00329531        TCAGAAAAGCAAGTTGCGCTCTTGACCAATGAGAGATATTTGAAGGAGGAAACACAATTA
XM_005248704.1      TCAGAAAAGCAAGTTGCGCTCTTGACCAATGAGAGATATTTGAAGGAGGAAACACAATTA
NM_181837.2         TCAGAAAAGCAAGTTGCGCTCTTGACCAATGAGAGATATTTGAAGGAGGAAACACAATTA
XM_005248705.1      TCAGAAAAGCAAGTTGCGCTCTTGACCAATGAGAGATATTTGAAGGAGGAAACACAATTA
NM_012381.3         TCAGAAAAGCAAGTTGCGCTCTTGACCAATGAGAGATATTTGAAGGAGGAAACACAATTA
XM_005248706.1      TCAGAAAAGCAAGTTGCGCTCTTGACCAATGAGAGATATTTGAAGGAGGAAACACAATTA
                    ************************************************************

HsCD00329531        TTACTAGAAAACCTGCATGTTTATCATATGAATTACTTCCTGGTTTTGAGATGTCTTCAT
XM_005248704.1      TTACTAGAAAACCTGCATGTTTATCATATGAATTACTTCCTGGTTTTGAGATGTCTTCAT
NM_181837.2         TTACTAGAAAACCTGCATGTTTATCATATGAATTACTTCCTGGTTTTGAGATGTCTTCAT
XM_005248705.1      TTACTAGAAAACCTGCATGTTTATCATATGAATTACTTCCTGGTTTTGAGATGTCTTCAT
NM_012381.3         TTACTAGAAAACCTGCATGTTTATCATATGAATTACTTCCTGGTTTTGAGATGTCTTCAT
XM_005248706.1      TTACTAGAAAACCTGCATGTTTATCATATGAATTACTTCCTGGTTTTGAGATGTCTTCAT
                    ************************************************************

HsCD00329531        AAGTTCACCTCTTCTCTTCCCAAGTATCCACTAGGTCGACAGATCAGAGAGTTGTACTGT
XM_005248704.1      AAGTTCACCTCTTCTCTTCCCAAGTATCCACTAGGTCGACAGATCAGAGAGTTGTACTGT
NM_181837.2         AAGTTCACCTCTTCTCTTCCCAAGTATCCACTAGGTCGACAGATCAGAGAGTTGTACTGT
XM_005248705.1      AAGTTCACCTCTTCTCTTCCCAAGTATCCACTAGGTCGACAGATCAGAGAGTTGTACTGT
NM_012381.3         AAGTTCACCTCTTCTCTTCCCAAGTATCCACTAGGTCGACAGATCAGAGAGTTGTACTGT
XM_005248706.1      AAGTTCACCTCTTCTCTTCCCAAGTATCCACTAGGTCGACAGATCAGAGAGTTGTACTGT
                    ************************************************************

HsCD00329531        ACATGTTTAGAAAAGAACATATGGGATTCAGAGGAGTATGCATCAGTCTTGCAGCTGCTG
XM_005248704.1      ACATGTTTAGAAAAGAACATATGGGATTCAGAGGAGTATGCATCAGTCTTGCAGCTGCTG
NM_181837.2         ACATGTTTAGAAAAGAACATATGGGATTCAGAGGAGTATGCATCAGTCTTGCAGCTGCTG
XM_005248705.1      ACATGTTTAGAAAAGAACATATGGGATTCAGAGGAGTATGCATCAGTCTTGCAGCTGCTG
NM_012381.3         ACATGTTTAGAAAAGAACATATGGGATTCAGAGGAGTATGCATCAGTCTTGCAGCTGCTG
XM_005248706.1      ACATGTTTAGAAAAGAACATATGGGATTCAGAGGAGTATGCATCAGTCTTGCAGCTGCTG
                    ************************************************************

HsCD00329531        AGGATGTTGGCAAAGGATGAACTGATGACCATACTTGAGAAATGTTTCAAGGTTTTTAAG
XM_005248704.1      AGGATGTTGGCAAAGGATGAACTGATGACCATACTTGAGAAATGTTTCAAGGTTTTTAAG
NM_181837.2         AGGATGTTGGCAAAGGATGAACTGATGACCATACTTGAGAAATGTTTCAAGGTTTTTAAG
XM_005248705.1      AGGATGTTGGCAAAGGATGAACTGATGACCATACTTGAGAAATGTTTCAAGGTTTTTAAG
NM_012381.3         AGGATGTTGGCAAAGGATGAACTGATGACCATACTTGAGAAATGTTTCAAGGTTTTTAAG
XM_005248706.1      AGGATGTTGGCAAAGGATGAACTGATGACCATACTTGAGAAATGTTTCAAGGTTTTTAAG
                    ************************************************************

HsCD00329531        TCTTATTGTGAAAACCACCTTGGCAGCACAGCTAAGAGAATAGAGGAGTTCCTGGCCCAG
XM_005248704.1      TCTTATTGTGAAAACCACCTTGGCAGCACAGCTAAGAGAATAGAGGAGTTCCTGGCCCAG
NM_181837.2         TCTTATTGTGAAAACCACCTTGGCAGCACAGCTAAGAGAATAGAGGAGTTCCTGGCCCAG
XM_005248705.1      TCTTATTGTGAAAACCACCTTGGCAGCACAGCTAAGAGAATAGAGGAGTTCCTGGCCCAG
NM_012381.3         TCTTATTGTGAAAACCACCTTGGCAGCACAGCTAAGAGAATAGAGGAGTTCCTGGCCCAG
XM_005248706.1      TCTTATTGTGAAAACCACCTTGGCAGCACAGCTAAGAGAATAGAGGAGTTCCTGGCCCAG
                    ************************************************************

HsCD00329531        TTTCAGAGCCTCGAT---GAAACCAAAGAGGAAGAAGATGCTTCTGGGTCACAGCCAAAG
XM_005248704.1      TTTCAGAGCCTCGATGCAGAAACCAAAGAGGAAGAAGATGCTTCTGGGTCACAGCCAAAG
NM_181837.2         TTTCAGAGCCTCGATGCAGAAACCAAAGAGGAAGAAGATGCTTCTGGGTCACAGCCAAAG
XM_005248705.1      TTTCAGAGCCTCGATGCAGAAACCAAAGAGGAAGAAGATGCTTCTGGGTCACAGCCAAAG
NM_012381.3         TTTCAGAGCCTCGAT---GAAACCAAAGAGGAAGAAGATGCTTCTGGGTCACAGCCAAAG
XM_005248706.1      TTTCAGAGCCTCGATGCAGAAACCAAAGAGGAAGAAGATGCTTCTGGGTCACAGCCAAAG
                    ***************   ******************************************

HsCD00329531        GGGCTTCAGAAGACAGACCTCTATCATCTTCAGAAGTCCTTATTGGAAATGAAGGAGTTA
XM_005248704.1      GGGCTTCAGAAGACAGACCTCTATCATCTTCAGAAGTCCTTATTGGAAATGAAGGAGTTA
NM_181837.2         GGGCTTCAGAAGACAGACCTCTATCATCTTCAGAAGTCCTTATTGGAAATGAAGGAGTTA
XM_005248705.1      GGGCTTCAGAAGACAGACCTCTATCATCTTCAGAAGTCCTTATTGGAAATGAAGGAGTTA
NM_012381.3         GGGCTTCAGAAGACAGACCTCTATCATCTTCAGAAGTCCTTATTGGAAATGAAGGAGTTA
XM_005248706.1      GGGCTTCAGAAGACAGACCTCTATCATCTTCAGAAGTCCTTATTGGAAATGAAGGAGTTA
                    ************************************************************

HsCD00329531        AGAAGAAGTAAGAAGCAAACCAAATTTGAAGTACTCAGAGAAAATGTTGTGAACTTCATT
XM_005248704.1      AGAAGAAGTAAGAAGCAAACCAAATTTGAAGTACTCAGAGAAAATGTTGTGAACTTCATT
NM_181837.2         AGAAGAAGTAAGAAGCAAACCAAATTTGAAGTACTCAGAGAAAATGTTGTGAACTTCATT
XM_005248705.1      AGAAGAAGTAAGAAGCAAACCAAATTTGAAGTACTCAGAGAAAATGTTGTGAACTTCATT
NM_012381.3         AGAAGAAGTAAGAAGCAAACCAAATTTGAAGTACTCAGAGAAAATGTTGTGAACTTCATT
XM_005248706.1      AGAAGAAGTAAGAAGCAAACCAAATTTGAAGTACTCAGAGAAAATGTTGTGAACTTCATT
                    ************************************************************

HsCD00329531        GACTGTCTAGTGAGAGAATACCTTCTGCCTCCTGAGACACAGCCTCTCCATGAGGTGGTG
XM_005248704.1      GACTGTCTAGTGAGAGAATACCTTCTGCCTCCTGAGACACAGCCTCTCCATGAGGTGGTG
NM_181837.2         GACTGTCTAGTGAGAGAATACCTTCTGCCTCCTGAGACACAGCCTCTCCATGAGGTGGTG
XM_005248705.1      GACTGTCTAGTGAGAGAATACCTTCTGCCTCCTGAGACACAGCCTCTCCATGAGGTGGTG
NM_012381.3         GACTGTCTAGTGAGAGAATACCTTCTGCCTCCTGAGACACAGCCTCTCCATGAGGTGGTG
XM_005248706.1      GACTGTCTAGTGAGAGAATACCTTCTGCCTCCTGAGACACAGCCTCTCCATGAGGTGGTG
                    ************************************************************

HsCD00329531        TACTTCAGTGCTGCCCATGCCCTTCGTGAGCATTTAAATGCTGCTCCGCGAATTGCCCTC
XM_005248704.1      TACTTCAGTGCTGCCCATGCCCTTCGTGAGCATTTAAATGCTGCTCCGCGAATTGCCCTC
NM_181837.2         TACTTCAGTGCTGCCCATGCCCTTCGTGAGCATTTAAATGCTGCTCCGCGAATTGCCCTC
XM_005248705.1      TACTTCAGTGCTGCCCATGCCCTTCGTGAGCATTTAAATGCTGCTCCGCGAATTGCCCTC
NM_012381.3         TACTTCAGTGCTGCCCATGCCCTTCGTGAGCATTTAAATGCTGCTCCGCGAATTGCCCTC
XM_005248706.1      TACTTCAGTGCTGCCCATGCCCTTCGTGAGCATTTAAATGCTGCTCCGCGAATTGCCCTC
                    ************************************************************

HsCD00329531        CATACTGCACTCAACAATCCTTACTATTATCTCAAGAATGAAGCACTGAAAAGCGAAGAA
XM_005248704.1      CATACTGCACTCAACAATCCTTACTATTATCTCAAGAATGAAGCACTGAAAAGCGAAGAA
NM_181837.2         CATACTGCACTCAACAATCCTTACTATTATCTCAAGAATGAAGCACTGAAAAGCGAAGAA
XM_005248705.1      CATACTGCACTCAACAATCCTTACTATTATCTCAAGAATGAAGCACTGAAAAGCGAAGAA
NM_012381.3         CATACTGCACTCAACAATCCTTACTATTATCTCAAGAATGAAGCACTGAAAAGCGAAGAA
XM_005248706.1      CATACTGCACTCAACAATCCTTACTATTATCTCAAGAATGAAGCACTGAAAAGCGAAGAA
                    ************************************************************

HsCD00329531        GGCTGCATTCCGAATATCGCCCCAGACATCTGCATAGCATACAAACTGCACCTAGAGTGT
XM_005248704.1      GGCTGCATTCCGAATATCGCCCCAGACATCTGCATAGCATACAAACTGCACCTAGAGTGT
NM_181837.2         GGCTGCATTCCGAATATCGCCCCAGACATCTGCATAGCATACAAACTGCACCTAGAGTGT
XM_005248705.1      GGCTGCATTCCGAATATCGCCCCAGACATCTGCATAGCATACAAACTGCACCTAGAGTGT
NM_012381.3         GGCTGCATTCCGAATATCGCCCCAGACATCTGCATAGCATACAAACTGCACCTAGAGTGT
XM_005248706.1      GGCTGCATTCCGAATATCGCCCCAGACATCTGCATAGCATACAAACTGCACCTAGAGTGT
                    ************************************************************

HsCD00329531        AGCAGGCTCATCAACCTCGTGGACTGGTCAGAGGCTTTTGCAACAGTTGTGACAGCTGCT
XM_005248704.1      AGCAGGCTCATCAACCTCGTGGACTGGTCAGAGGCTTTTGCAACAGTTGTGACAGCTGCT
NM_181837.2         AGCAGGCTCATCAACCTCGTGGACTGGTCAGAGGCTTTTGCAACAGTTGTGACAGCTGCT
XM_005248705.1      AGCAGGCTCATCAACCTCGTGGACTGGTCAGAGGCTTTTGCAACAGTTGTGACAGCTGCT
NM_012381.3         AGCAGGCTCATCAACCTCGTGGACTGGTCAGAGGCTTTTGCAACAGTTGTGACAGCTGCT
XM_005248706.1      AGCAGGCTCATCAACCTCGTGGACTGGTCAGAGGCTTTTGCAACAGTTGTGACAGCTGCT
                    ************************************************************

HsCD00329531        GAAAAAATGGATGCAAATTCTGCAACCTCAGAAGAAATGAATGAAATTATCCATGCTCGG
XM_005248704.1      GAAAAAATGGATGCAAATTCTGCAACCTCAGAAGAAATGAATGAAATTATCCACCTCCAG
NM_181837.2         GAAAAAATGGATGCAAATTCTGCAACCTCAGAAGAAATGAATGAAATTATCCATGCTCGG
XM_005248705.1      GAAAAAATGGATGCAAATTCTGCAACCTCAGAAGAAATGAATGAAATTATCCATGCTCGG
NM_012381.3         GAAAAAATGGATGCAAATTCTGCAACCTCAGAAGAAATGAATGAAATTATCCATGCTCGG
XM_005248706.1      GAAAAAATGGATGCAAATTCTGCAACCTCAGAAGAAATGAATGAAATTATCCATGCTCGG
                    *****************************************************    *.*

HsCD00329531        TTTATTAGAGCTGTTTCTGAACTAGAACTTTTAGGATTTATAAAACCTACCAAACAGAAG
XM_005248704.1      TGCTCGGTTTATTAG---------------------------------------------
NM_181837.2         TTTATTAGAGCTGTTTCTGAACTAGAACTTTTAGGATTTATAAAACCTACCAAACAGAAG
XM_005248705.1      TTTATTAGAGCTGTTTCTGAACTAGAACTTTTAGGATTTATAAAACCTACCAAACAGAAG
NM_012381.3         TTTATTAGAGCTGTTTCTGAACTAGAACTTTTAGGATTTATAAAACCTACCAAACAGAAG
XM_005248706.1      TTTATTAGAGCTGTTTCTGAACTAGAACTTTTAGGATTTATAAAACCTACCAAACAGAAG
                    *  :  . : .* :                                              

HsCD00329531        ACTGACCATGTGGCAAGACTAACATGGGGAGGCTGCTTG
XM_005248704.1      ---------------------------------------
NM_181837.2         ACTGACCATGTGGCAAGACTAACATGGGGAGGCTGCTAG
XM_005248705.1      ACTGACCATGTGGCAAGACTAACATGGGGAGGCTGCTAG
NM_012381.3         ACTGACCATGTGGCAAGACTAACATGGGGAGGCTGCTAG
XM_005248706.1      ACTGACCATGTGGCAAGACTAACATGGGGAGGCTGCTAG
                                                           

Pathways

Reactome : Activation of ATR in response to replication stress
Reactome : Activation of the pre-replicative complex
Reactome : Assembly of the ORC complex at the origin of replication
Reactome : Assembly of the pre-replicative complex
Reactome : Association of licensing factors with the pre-replicative complex
Reactome : CDC6 association with the ORC:origin complex
Reactome : CDT1 association with the CDC6:ORC:origin complex
Reactome : Cell Cycle
Reactome : Cell Cycle Checkpoints
Reactome : Cell Cycle, Mitotic
Reactome : DNA Replication
Reactome : DNA Replication Pre-Initiation
Reactome : E2F mediated regulation of DNA replication
Reactome : E2F-enabled inhibition of pre-replication complex formation
Reactome : G1/S Transition
Reactome : G2/M Checkpoints
Reactome : M/G1 Transition
Reactome : Mitotic G1-G1/S phases
Reactome : Mitotic M-M/G1 phases
Reactome : Orc1 removal from chromatin
Reactome : Regulation of DNA replication
Reactome : Removal of licensing factors from origins
Reactome : S Phase
Reactome : Switching of origins to a post-replicative state
Reactome : Synthesis of DNA
WikiPathway : Cell cycle
WikiPathway : DNA Replication
WikiPathway : G1 to S cell cycle control

Protein

UniProt : Q9UBD5
UniProt : B4E025
HPRD : 05398

Clone

Cloning Information : 268421
HIP Master Clone ID : 194928
Original Clone ID : FLH268421.01L

Organism


TAX_ID : 9606
Species Specific ID: 23595

Genome

Chromosome : 6
Map Location : 6q14.3-q16.1
Ensembl : ENSG00000135336

Reagents

Labome : ORC3-antibody