| Gene: |
Gene Symbol:
MAPK3 Gene Name: mitogen-activated protein kinase 3 Sequence Map: pDNR-Dual_with_human_insert.pdf |
|---|---|
| Original Clone ID: | FLH019083.01L |
| Keyword: | None |
| Species: | Homo sapiens |
| Type: | cDNA |
| Vector Name: | pDNR-Dual Format: FUSION |
| Source: | HIP |
| Description: | None |
| Comments: | None |
| Mutation/ Discrepancy : |
No / No |
| Publications: |
PMID: 15928075 Title: Building a human kinase gene repository: bioinformatics, molecular cloning, and functional validation. |
| Authors: |
HIP |
|
HsCD00000342 Price: Login for Pricing AVAILABLE No restriction Special MTA: None |
|
Insert sequence: 1140nts
Open reading frame : 1 to 1140 Reference Sequence Alignment ATGGCGGCGGCGGCGGCTCAGGGGGGCGGGGGCGGGGAGCCCCGTAGAACCGAGGGGGTC
GGCCCGGGGGTCCCGGGGGAGGTGGAGATGGTGAAGGGGCAGCCGTTCGACGTGGGCCCG
CGCTACACGCAGTTGCAGTACATCGGCGAGGGCGCGTACGGCATGGTCAGCTCGGCCTAT
GACCACGTGCGCAAGACTCGCGTGGCCATCAAGAAGATCAGCCCCTTCGAACATCAGACC
TACTGCCAGCGCACGCTCCGGGAGATCCAGATCCTGCTGCGCTTCCGCCATGAGAATGTC
ATCGGCATCCGAGACATTCTGCGGGCGTCCACCCTGGAAGCCATGAGAGATGTCTACATT
GTGCAGGACCTGATGGAGACTGACCTGTACAAGTTGCTGAAAAGCCAGCAGCTGAGCAAT
GACCATATCTGCTACTTCCTCTACCAGATCCTGCGGGGCCTCAAGTACATCCACTCCGCC
AACGTGCTCCACCGAGATCTAAAGCCCTCCAACCTGCTCATCAACACCACCTGCGACCTT
AAGATTTGTGATTTCGGCCTGGCCCGGATTGCCGATCCTGAGCATGACCACACCGGCTTC
CTGACGGAGTATGTGGCTACGCGCTGGTACCGGGCCCCAGAGATCATGCTGAACTCCAAG
GGCTATACCAAGTCCATCGACATCTGGTCTGTGGGCTGCATTCTGGCTGAGATGCTCTCT
AACCGGCCCATCTTCCCTGGCAAGCACTACCTGGATCAGCTCAACCACATTCTGGGCATC
CTGGGCTCCCCATCCCAGGAGGACCTGAATTGTATCATCAACATGAAGGCCCGAAACTAC
CTACAGTCTCTGCCCTCCAAGACCAAGGTGGCTTGGGCCAAGCTTTTCCCCAAGTCAGAC
TCCAAAGCCCTTGACCTGCTGGACCGGATGTTAACCTTTAACCCCAATAAACGGATCACA
GTGGAGGAAGCGCTGGCTCACCCCTACCTGGAGCAGTACTATGACCCGACGGATGAGCCA
GTGGCCGAGGAGCCCTTCACCTTCGCCATGGAGCTGGATGACCTACCTAAGGAGCGGCTG
AAGGAGCTCATCTTCCAGGAGACAGCACGCTTCCAGCCCGGAGTGCTGGAGGCCCCCTTG
|
| Coding Sequence Details | |
|---|---|
| Insert Sequence Verified?: Y | Verification Method: Sequence Verification |
|
Reference Sequence Annotations: End on reference sequence 1151 Start on reference sequence 12 |
|
|
Mutations: None |
Discrepancy: None |
5' Linker Sequence:
5P GCGGCCGCATAACTTCGTATAGCATACATTATACGAAGTTATCAGTC GACACC(ATG-GOI) |
|
3' Linker Sequence:
5p (goi-stop)GGAAGCTTTCTAGACCATTCGTTTGGCGCGCGGGCCC |
|
| Distributed in bacterial strain : | DH5-alpha T1 phage resistant |
|---|---|
| Antibiotic Selection: |
Host Type:
bacterial
Marker:
ampicillin Bacterial Selection Condition: 100 ug/mL ampicillin Growth Condition: Growth with the single antibiotic in LB at 37 degrees is recommended. Comments: Commonly used conditions for ampicillin resistant plasmid clones. |
| Protein Expression Results: | None |
| Recommended expression in: | Not Applicable |
Powered by LabGenius |
||
| Vector Name: | pDNR-Dual |
pDNR-Dual in advanced viewed |
| Synonyms: | '' | |
| Sequencing Primer: | Forward:
M13F
Reverse: Unknown |
|
| Description: | Recombinational donor/master vector with 6xHN tag ORF, T7 and M13 primer sites; ampicillin resistance; restriction enzyme cloning (into) and recombinational cloning (from). | |
| Comments: | The position of features were detemined for the empty form of the vector, which is described in detail on the BD/Clontech website. Subcloning into the MCS was performed using the infusion reaction strategy and some restriction sites in the MCS may be lost after an insert is added. | |
| Size (bp): | 4938 | |
| Parent Vector: | None | |
| Empty Vector: | None | |
| Properties: | Creator, donor (entry), loxP, multiple cloning site, recombinational cloning, with tag/fusion/marker | |
| Author Name: |
BD Biosciences Clontech |
|
| Publications: | None | |
| Vector Map: |
Vector Sequence:
|
|
| Sequence: |
Vector Features:
| Type | Name | Description | Start Position | End Position |
|---|---|---|---|---|
| MCS | MCS | restriction enzyme-type multiple cloning site | 45 | 129 |
| bacterial origin | ColE1 | ColE1 (pUC-type) origin of replication | 4111 | 4574 |
| negative selection marker | SacB | SacB negative selection marker gene (sucrose sensitivity) | 1057 | 2972 |
| primer site | M13 primer | M13 primer sequencing site | 4839 | 4855 |
| primer site | T7 primer | T7 RNA Pol primer sequencing site | 4865 | 4883 |
| recombination site | loxP site | loxP recombination site | 9 | 42 |
| recombination site | loxP site | loxP recombination site | 1015 | 1048 |
| selectable marker | CmR | chloramphenicol resistance gene ORF (functional only after recombination of insert into vector with promoter) | 986 | 327 |
| selectable marker | AmpR | ampicillin resistance gene | 3103 | 3963 |
| splice donor site | SD site | splice donor site | 132 | 136 |
| tag | HN | 6xHN epitope tag | 141 | 176 |
- Gene
- Pathways
- Protein
- Clone
- Organism
- Genome
- Reagents
Gene
| Gene Symbol : | MAPK3 |
|---|---|
| Symbol Nomenclature : | MAPK3 |
| SYNONYM : | ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK |
| Designation : | MAP kinase isoform p44|MAPK 1|extracellular signal-regulated kinase 1|extracellular signal-related kinase 1|insulin-stimulated MAP2 kinase|microtubule-associated protein 2 kinase |
| Full Nomenclature : | mitogen-activated protein kinase 3 |
| GENEID : | 5595 |
| GI : | 61365421 |
| GenBank Accession : | AY890764 |
| HGNC : | 6877 |
| MIM : | 601795 |
| Vega : | OTTHUMG00000132149 |
| Target GenBank: | BC013992 |
Reference Sequence Alignment
HsCD00000342 ATGGCGGCGGCGGCGGCTCAGGGGGGCGGGGGCGGGGAGCCCCGTAGAACCGAGGGGGTC
NM_001040056.2 ATGGCGGCGGCGGCGGCTCAGGGGGGCGGGGGCGGGGAGCCCCGTAGAACCGAGGGGGTC
NM_002746.2 ATGGCGGCGGCGGCGGCTCAGGGGGGCGGGGGCGGGGAGCCCCGTAGAACCGAGGGGGTC
************************************************************
HsCD00000342 GGCCCGGGGGTCCCGGGGGAGGTGGAGATGGTGAAGGGGCAGCCGTTCGACGTGGGCCCG
NM_001040056.2 GGCCCGGGGGTCCCGGGGGAGGTGGAGATGGTGAAGGGGCAGCCGTTCGACGTGGGCCCG
NM_002746.2 GGCCCGGGGGTCCCGGGGGAGGTGGAGATGGTGAAGGGGCAGCCGTTCGACGTGGGCCCG
************************************************************
HsCD00000342 CGCTACACGCAGTTGCAGTACATCGGCGAGGGCGCGTACGGCATGGTCAGCTCGGCCTAT
NM_001040056.2 CGCTACACGCAGTTGCAGTACATCGGCGAGGGCGCGTACGGCATGGTCAGCTCGGCCTAT
NM_002746.2 CGCTACACGCAGTTGCAGTACATCGGCGAGGGCGCGTACGGCATGGTCAGCTCGGCCTAT
************************************************************
HsCD00000342 GACCACGTGCGCAAGACTCGCGTGGCCATCAAGAAGATCAGCCCCTTCGAACATCAGACC
NM_001040056.2 GACCACGTGCGCAAGACTCGCGTGGCCATCAAGAAGATCAGCCCCTTCGAACATCAGACC
NM_002746.2 GACCACGTGCGCAAGACTCGCGTGGCCATCAAGAAGATCAGCCCCTTCGAACATCAGACC
************************************************************
HsCD00000342 TACTGCCAGCGCACGCTCCGGGAGATCCAGATCCTGCTGCGCTTCCGCCATGAGAATGTC
NM_001040056.2 TACTGCCAGCGCACGCTCCGGGAGATCCAGATCCTGCTGCGCTTCCGCCATGAGAATGTC
NM_002746.2 TACTGCCAGCGCACGCTCCGGGAGATCCAGATCCTGCTGCGCTTCCGCCATGAGAATGTC
************************************************************
HsCD00000342 ATCGGCATCCGAGACATTCTGCGGGCGTCCACCCTGGAAGCCATGAGAGATGTCTACATT
NM_001040056.2 ATCGGCATCCGAGACATTCTGCGGGCGTCCACCCTGGAAGCCATGAGAGATGTCTACATT
NM_002746.2 ATCGGCATCCGAGACATTCTGCGGGCGTCCACCCTGGAAGCCATGAGAGATGTCTACATT
************************************************************
HsCD00000342 GTGCAGGACCTGATGGAGACTGACCTGTACAAGTTGCTGAAAAGCCAGCAGCTGAGCAAT
NM_001040056.2 GTGCAGGACCTGATGGAGACTGACCTGTACAAGTTGCTGAAAAGCCAGCAGCTGAGCAAT
NM_002746.2 GTGCAGGACCTGATGGAGACTGACCTGTACAAGTTGCTGAAAAGCCAGCAGCTGAGCAAT
************************************************************
HsCD00000342 GACCATATCTGCTACTTCCTCTACCAGATCCTGCGGGGCCTCAAGTACATCCACTCCGCC
NM_001040056.2 GACCATATCTGCTACTTCCTCTACCAGATCCTGCGGGGCCTCAAGTACATCCACTCCGCC
NM_002746.2 GACCATATCTGCTACTTCCTCTACCAGATCCTGCGGGGCCTCAAGTACATCCACTCCGCC
************************************************************
HsCD00000342 AACGTGCTCCACCGAGATCTAAAGCCCTCCAACCTGCTCATCAACACCACCTGCGACCTT
NM_001040056.2 AACGTGCTCCACCGAGATCTAAAGCCCTCCAACCTGCTCATCAACACCACCTGCGACCTT
NM_002746.2 AACGTGCTCCACCGAGATCTAAAGCCCTCCAACCTGCTCATCAACACCACCTGCGACCTT
************************************************************
HsCD00000342 AAGATTTGTGATTTCGGCCTGGCCCGGATTGCCGATCCTGAGCATGACCACACCGGCTTC
NM_001040056.2 AAGATTTGTGATTTCGGCCTGGCCCGGATTGCCGATCCTGAGCATGACCACACCGGCTTC
NM_002746.2 AAGATTTGTGATTTCGGCCTGGCCCGGATTGCCGATCCTGAGCATGACCACACCGGCTTC
************************************************************
HsCD00000342 CTGACGGAGTATGTGGCTACGCGCTGGTACCGGGCCCCAGAGATCATGCTGAACTCCAAG
NM_001040056.2 CTGACGGAGTATGTGGCTACGCGCTGGTACCGGGCCCCAGAGATCATGCTGAACTCCAAG
NM_002746.2 CTGACGGAGTATGTGGCTACGCGCTGGTACCGGGCCCCAGAGATCATGCTGAACTCCAAG
************************************************************
HsCD00000342 GGCTATACCAAGTCCATCGACATCTGGTCTGTGGGCTGCATTCTGGCTGAGATGCTCTCT
NM_001040056.2 GGCTATACCAAGTCCATCGACATCTGGTCTGTGGGCTGCATTCTGGCTGAGATGCTCTCT
NM_002746.2 GGCTATACCAAGTCCATCGACATCTGGTCTGTGGGCTGCATTCTGGCTGAGATGCTCTCT
************************************************************
HsCD00000342 AACCGGCCCATCTTCCCTGGCAAGCACTACCTGGATCAGCTCAACCACATTCTGGGCATC
NM_001040056.2 AACCGGCCCATCTTCCCTGGCAAGCACTACCTGGATCAGCTCAACCACATTCTGGGCATC
NM_002746.2 AACCGGCCCATCTTCCCTGGCAAGCACTACCTGGATCAGCTCAACCACATTCTGGGCATC
************************************************************
HsCD00000342 CTGGGCTCCCCATCCCAGGAGGACCTGAATTGTATCATCAACATGAAGGCCCGAAACTAC
NM_001040056.2 CTGGGCTCCCCATCCCAGGAGGACCTGAATTGTATCATCAACATGAAGGCCCGAAACTAC
NM_002746.2 CTGGGCTCCCCATCCCAGGAGGACCTGAATTGTATCATCAACATGAAGGCCCGAAACTAC
************************************************************
HsCD00000342 CTACAGTCTCTGCCCTCCAAGACCAAGGTGGCTTGGGCCAAGCTTTTCCCCAAGTCAGAC
NM_001040056.2 CTACAGTCTCTGCCCTCCAAGACCAAGGTGGCTTGGGCCAAGCTTTTCCCCAAGTCAGAC
NM_002746.2 CTACAGTCTCTGCCCTCCAAGACCAAGGTGGCTTGGGCCAAGCTTTTCCCCAAGTCAGAC
************************************************************
HsCD00000342 TCCAAAGCCCTTGACCTGCTGGACCGGATGTTAACCTTTAACCCCAATAAACGGATCACA
NM_001040056.2 TCCAAAGCCCTTGACCTGCTGGACCGGATGTTAACCTTTAACCCCAATAAACGGATCACA
NM_002746.2 TCCAAAGCCCTTGACCTGCTGGACCGGATGTTAACCTTTAACCCCAATAAACGGATCACA
************************************************************
HsCD00000342 GTGGAGGAAGCGCTGGCTCACCCCTACCTGGAGCAGTACTATGACCCGACGGATGAGCCA
NM_001040056.2 GTGGAGGAAGCGCTGGCTCACCCCTACCTGGAGCAGTACTATGACCCGACGGATGAGGTG
NM_002746.2 GTGGAGGAAGCGCTGGCTCACCCCTACCTGGAGCAGTACTATGACCCGACGGATGAGCCA
********************************************************* .
HsCD00000342 GTGGCCGAGGAGCCCTTCACCTTCGCCATGGAGCTGGATGACCTACCTAAGGAGCGGCTG
NM_001040056.2 GG----------------------------------------------------------
NM_002746.2 GTGGCCGAGGAGCCCTTCACCTTCGCCATGGAGCTGGATGACCTACCTAAGGAGCGGCTG
*
HsCD00000342 AAGGAGCTCATCTTCCAGGAGACAGCACGCTTCCAGCCCGGAGTGCTGGAGGCCCCCTTG
NM_001040056.2 --------CCAGTCCCCAGCAGCAGTGGGGCTGGGGGCAGGGGAGCAGGGGGGCACGTAG
NM_002746.2 AAGGAGCTCATCTTCCAGGAGACAGCACGCTTCCAGCCCGGAGTGCTGGAGGCCCCCTAG
*.: * **..*...*** . * * .* *.**.*:**:**.** *.* *:*
Pathways
| NCI : | ALK1 signaling events |
|---|---|
| NCI : | Alpha-synuclein signaling |
| NCI : | Angiopoietin receptor Tie2-mediated signaling |
| NCI : | Arf6 downstream pathway |
| NCI : | ATF-2 transcription factor network |
| NCI : | BCR signaling pathway |
| NCI : | CDC42 signaling events |
| NCI : | Cellular roles of Anthrax toxin |
| NCI : | Ceramide signaling pathway |
| NCI : | CXCR3-mediated signaling events |
| NCI : | Downstream signaling in naïve CD8+ T cells |
| NCI : | EGF receptor (ErbB1) signaling pathway |
| NCI : | Endothelins |
| NCI : | EPHB forward signaling |
| NCI : | ErbB1 downstream signaling |
| NCI : | ErbB2/ErbB3 signaling events |
| NCI : | ErbB4 signaling events |
| NCI : | Fc-epsilon receptor I signaling in mast cells |
| NCI : | FGF signaling pathway |
| NCI : | Glucocorticoid receptor regulatory network |
| NCI : | GMCSF-mediated signaling events |
| NCI : | IFN-gamma pathway |
| NCI : | IL2-mediated signaling events |
| NCI : | Integrins in angiogenesis |
| NCI : | mTOR signaling pathway |
| NCI : | Netrin-mediated signaling events |
| NCI : | Neurotrophic factor-mediated Trk receptor signaling |
| NCI : | Nongenotropic Androgen signaling |
| NCI : | Osteopontin-mediated events |
| NCI : | PDGFR-beta signaling pathway |
| NCI : | Presenilin action in Notch and Wnt signaling |
| NCI : | Ras signaling in the CD4+ TCR pathway |
| NCI : | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| NCI : | Regulation of Telomerase |
| NCI : | Retinoic acid receptors-mediated signaling |
| NCI : | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| NCI : | S1P1 pathway |
| NCI : | S1P2 pathway |
| NCI : | S1P3 pathway |
| NCI : | S1P4 pathway |
| NCI : | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| NCI : | Signaling events mediated by PRL |
| NCI : | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| NCI : | Signaling events mediated by VEGFR1 and VEGFR2 |
| NCI : | Signaling events regulated by Ret tyrosine kinase |
| NCI : | Syndecan-1-mediated signaling events |
| NCI : | Syndecan-2-mediated signaling events |
| NCI : | TRAIL signaling pathway |
| NCI : | Trk receptor signaling mediated by the MAPK pathway |
| NCI : | VEGFR1 specific signals |
| NCI : | VEGFR3 signaling in lymphatic endothelium |
| Panther : | Alzheimer disease-amyloid secretase pathway |
| Panther : | Angiogenesis |
| Panther : | Angiotensin II-stimulated signaling through G proteins and beta-arrestin |
| Panther : | Apoptosis signaling pathway |
| Panther : | B cell activation |
| Panther : | EGF receptor signaling pathway |
| Panther : | Endothelin signaling pathway |
| Panther : | FGF signaling pathway |
| Panther : | Inflammation mediated by chemokine and cytokine signaling pathway |
| Panther : | Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade |
| Panther : | Integrin signalling pathway |
| Panther : | Interferon-gamma signaling pathway |
| Panther : | Interleukin signaling pathway |
| Panther : | Parkinson disease |
| Panther : | PDGF signaling pathway |
| Panther : | Ras Pathway |
| Panther : | T cell activation |
| Panther : | TGF-beta signaling pathway |
| Panther : | Toll receptor signaling pathway |
| Panther : | VEGF signaling pathway |
| Reactome : | Activated TLR4 signalling |
| Reactome : | Activation of the AP-1 family of transcription factors |
| Reactome : | Advanced glycosylation endproduct receptor signaling |
| Reactome : | Antiviral mechanism by IFN-stimulated genes |
| Reactome : | ARMS-mediated activation |
| Reactome : | Axon guidance |
| Reactome : | Cell Cycle |
| Reactome : | Cell Cycle, Mitotic |
| Reactome : | Cellular response to heat stress |
| Reactome : | Cellular responses to stress |
| Reactome : | Cellular Senescence |
| Reactome : | Cytokine Signaling in Immune system |
| Reactome : | DAP12 interactions |
| Reactome : | DAP12 signaling |
| Reactome : | Developmental Biology |
| Reactome : | Disease |
| Reactome : | Downstream signal transduction |
| Reactome : | Downstream signaling of activated FGFR |
| Reactome : | ERK activation |
| Reactome : | ERK/MAPK targets |
| Reactome : | ERK1 activation |
| Reactome : | ERKs are inactivated |
| Reactome : | Fc epsilon receptor (FCERI) signaling |
| Reactome : | FCERI mediated MAPK activation |
| Reactome : | Fcgamma receptor (FCGR) dependent phagocytosis |
| Reactome : | Frs2-mediated activation |
| Reactome : | FRS2-mediated cascade |
| Reactome : | Gastrin-CREB signalling pathway via PKC and MAPK |
| Reactome : | Gene Expression |
| Reactome : | Golgi Cisternae Pericentriolar Stack Reorganization |
| Reactome : | GRB2 events in EGFR signaling |
| Reactome : | GRB2 events in ERBB2 signaling |
| Reactome : | Growth hormone receptor signaling |
| Reactome : | Hemostasis |
| Reactome : | IGF1R signaling cascade |
| Reactome : | Immune System |
| Reactome : | Innate Immune System |
| Reactome : | Insulin receptor signalling cascade |
| Reactome : | Interferon Signaling |
| Reactome : | Interleukin-2 signaling |
| Reactome : | IRS-mediated signalling |
| Reactome : | IRS-related events |
| Reactome : | IRS-related events triggered by IGF1R |
| Reactome : | ISG15 antiviral mechanism |
| Reactome : | L1CAM interactions |
| Reactome : | M Phase |
| Reactome : | MAP kinase activation in TLR cascade |
| Reactome : | MAPK targets/ Nuclear events mediated by MAP kinases |
| Reactome : | Mitotic M-M/G1 phases |
| Reactome : | Mitotic Prophase |
| Reactome : | MyD88 cascade initiated on plasma membrane |
| Reactome : | MyD88 dependent cascade initiated on endosome |
| Reactome : | MyD88-independent cascade |
| Reactome : | MyD88:Mal cascade initiated on plasma membrane |
| Reactome : | NCAM signaling for neurite out-growth |
| Reactome : | Negative regulation of FGFR signaling |
| Reactome : | NGF signalling via TRKA from the plasma membrane |
| Reactome : | Nuclear Events (kinase and transcription factor activation) |
| Reactome : | Oncogene Induced Senescence |
| Reactome : | Oxidative Stress Induced Senescence |
| Reactome : | Platelet activation, signaling and aggregation |
| Reactome : | Prolonged ERK activation events |
| Reactome : | RAF/MAP kinase cascade |
| Reactome : | Regulation of actin dynamics for phagocytic cup formation |
| Reactome : | Regulation of HSF1-mediated heat shock response |
| Reactome : | RNA Polymerase I Promoter Clearance |
| Reactome : | RNA Polymerase I Promoter Opening |
| Reactome : | RNA Polymerase I Transcription |
| Reactome : | RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription |
| Reactome : | Senescence-Associated Secretory Phenotype (SASP) |
| Reactome : | SHC-mediated signalling |
| Reactome : | SHC-related events |
| Reactome : | SHC-related events triggered by IGF1R |
| Reactome : | SHC1 events in EGFR signaling |
| Reactome : | SHC1 events in ERBB2 signaling |
| Reactome : | SHC1 events in ERBB4 signaling |
| Reactome : | Signal attenuation |
| Reactome : | Signal Transduction |
| Reactome : | Signal transduction by L1 |
| Reactome : | Signaling by EGFR |
| Reactome : | Signaling by EGFR in Cancer |
| Reactome : | Signaling by ERBB2 |
| Reactome : | Signaling by ERBB4 |
| Reactome : | Signaling by FGFR |
| Reactome : | Signaling by FGFR in disease |
| Reactome : | Signaling by GPCR |
| Reactome : | Signaling by Insulin receptor |
| Reactome : | Signaling by Interleukins |
| Reactome : | Signaling by Leptin |
| Reactome : | Signaling by PDGF |
| Reactome : | Signaling by SCF-KIT |
| Reactome : | Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) |
| Reactome : | Signalling by NGF |
| Reactome : | Signalling to ERKs |
| Reactome : | Signalling to p38 via RIT and RIN |
| Reactome : | Signalling to RAS |
| Reactome : | SOS-mediated signalling |
| Reactome : | Spry regulation of FGF signaling |
| Reactome : | Thrombin signalling through proteinase activated receptors (PARs) |
| Reactome : | Toll Like Receptor 10 (TLR10) Cascade |
| Reactome : | Toll Like Receptor 2 (TLR2) Cascade |
| Reactome : | Toll Like Receptor 3 (TLR3) Cascade |
| Reactome : | Toll Like Receptor 4 (TLR4) Cascade |
| Reactome : | Toll Like Receptor 5 (TLR5) Cascade |
| Reactome : | Toll Like Receptor 7/8 (TLR7/8) Cascade |
| Reactome : | Toll Like Receptor 9 (TLR9) Cascade |
| Reactome : | Toll Like Receptor TLR1:TLR2 Cascade |
| Reactome : | Toll Like Receptor TLR6:TLR2 Cascade |
| Reactome : | Toll-Like Receptors Cascades |
| Reactome : | TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation |
| Reactome : | TRAF6 Mediated Induction of proinflammatory cytokines |
| Reactome : | Transcription |
| Reactome : | TRIF-mediated TLR3/TLR4 signaling |
| WikiPathway : | Alpha 6 Beta 4 signaling pathway |
| WikiPathway : | Alzheimers Disease |
| WikiPathway : | Apoptosis Modulation and Signaling |
| WikiPathway : | EPO Receptor Signaling |
| WikiPathway : | FSH signaling pathway |
| WikiPathway : | Hypothetical Network for Drug Addiction |
| WikiPathway : | IL-1 signaling pathway |
| WikiPathway : | IL-2 Signaling pathway |
| WikiPathway : | IL-3 Signaling Pathway |
| WikiPathway : | IL-4 signaling pathway |
| WikiPathway : | IL-5 signaling pathway |
| WikiPathway : | IL-6 signaling pathway |
| WikiPathway : | IL-7 signaling pathway |
| WikiPathway : | IL-9 signaling pathway |
| WikiPathway : | Insulin Signaling |
| WikiPathway : | Kit receptor signaling pathway |
| WikiPathway : | Leptin signaling pathway |
| WikiPathway : | MAPK Cascade |
| WikiPathway : | MAPK signaling pathway |
| WikiPathway : | MicroRNAs in cardiomyocyte hypertrophy |
| WikiPathway : | Osteopontin Signaling |
| WikiPathway : | Prolactin Signaling Pathway |
| WikiPathway : | RANKL/RANK Signaling Pathway |
| WikiPathway : | Regulation of Actin Cytoskeleton |
| WikiPathway : | Regulation of toll-like receptor signaling pathway |
| WikiPathway : | Serotonin HTR1 Group and FOS Pathway |
| WikiPathway : | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling |
| WikiPathway : | Serotonin Receptor 4/6/7 and NR3C Signaling |
| WikiPathway : | Signal Transduction of S1P Receptor |
| WikiPathway : | Signaling of Hepatocyte Growth Factor Receptor |
| WikiPathway : | TCR Signaling Pathway |
| WikiPathway : | TGF Beta Signaling Pathway |
| WikiPathway : | TNF alpha Signaling Pathway |
| WikiPathway : | Toll-like receptor signaling pathway |
| WikiPathway : | TSH signaling pathway |
| WikiPathway : | TWEAK Signaling Pathway |
Protein
| SMART domain : | S_TKc : Serine/Threonine protein kinases, catalytic domain |
|---|---|
| SMART domain : | TyrKc : Tyrosine kinase, catalytic domain |
| UniProt : | Q8NHX1 |
| UniProt : | P27361 |
| UniProt : | Q9BWJ1 |
| UniProt : | A8CZ58 |
| HPRD : | 03479 |
Clone
| Cloning Information : | 19083 |
|---|---|
| HIP Master Clone ID : | 33282 |
| Original Clone ID : | FLH019083.01L |
Organism
| TAX_ID : | 9606 |
|---|---|
| Species Specific ID: | 5595 |
Genome
| Chromosome : | 16 |
|---|---|
| Map Location : | 16p11.2 |
| Ensembl : | ENSG00000102882 |
Reagents
| Labome : | ERK1-antibody |
|---|
