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GRB7 (Homo sapiens) in pJP1520 (retroviral expression vector)

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Explanation of Terms


Gene: Gene Symbol:  GRB7
Gene Name:  growth factor receptor-bound protein 7
Sequence             
Original Clone ID: FLH213100.01X
Keyword: None
Species: Homo sapiens
Type: cDNA
Vector Name: pJP1520               Format:  CLOSED
Source: HIP
Description: None
Comments: None
Mutation/
Discrepancy :
No / No
Publications: None
Authors:
HsCD00074508

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AVAILABLE
No restriction
Special MTA: None

 

Insert sequence: 1599nts         Open reading frame : 1 to 1599
Reference Sequence Alignment

ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTTTGCCCAGCC
CCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAGGAGGTAAAG
AGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAGGAGAGGCGT
GCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCTCCCTCACAG
AGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGATGCCAGCCGC
CCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAGGTGGCAGCA
GGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCCTTGAGCGAC
GAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGTTTGGAGGAC
CACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGCCGCTTCGTC
TTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCCCTGTTCCCA
GAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAAGACCTCATC
CAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAGCTGCGGGGT
TCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGCCTCTATTAC
TCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGATGTGAACGAG
TCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACTGACTTCGGT
TTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATCTTCTGCAGT
GAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAGTACGGGGTG
CAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCTTGTTTGGGC
TCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTCTCTGGCCAT
GCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAGGAGGCCCAG
GCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCCGGCACGAGC
CTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCCCGTGAGGAG
AGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTCCGGGAGAGT
CAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTGAAGCATTAT
CTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGATGGCCAGACC
CGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGCATCCTGCCG
TGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTAG


Coding Sequence Details
Insert Sequence Verified?: Y Verification Method: Insert was fully sequenced in parent vector; Verification by restriction enzyme digest
Reference Sequence Annotations:
End on reference sequence 1714
Start on reference sequence 116
Mutations:
None
Discrepancy:
None
5' Linker Sequence:
5P GCGGCCGCATAACTTCGTATAGCATACATTATACGAAGTTATCAGTC
GACACC(ATG-GOI)

3' Linker Sequence:
5p (goi-stop)GGAAGCTTTCTAGACCATTCGTTTGGCGCGCGGGCCC

 

 Recommended Growth Condition:

Distributed in bacterial strain : DH5-alpha T1 phage resistant
Antibiotic Selection: Host Type:  bacterial    Marker:  ampicillin
Host Type:  bacterial    Marker:  chloramphenicol
Host Type:  mammalian    Marker:  puromycin
Bacterial Selection Condition:  100 ug/mL ampicillin, 34 ug/mL chloramphenicol
Growth Condition:  Growth with the double antibiotic in LB supplemented with 7% sucrose at 37 degrees is recommended.
Comments:  Conditions for Creator-type vectors in with insert (recombined) form. Selection differs for the unrecombined, empty form of the vectors.
Protein Expression Results: None
Recommended expression in: Not Applicable
       DyNA Vector Map

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Vector Name: pJP1520

pJP1520 in advanced viewed

Synonyms: None
Sequencing Primer: Forward:  JPO113
Reverse:  Unknown
Description: Retroviral expression vector with CMV promoter, MMV-type 5p and 3p LTRs; amp resistance (puromycin for mammalian selection); recombinational cloning.
Comments: One in a series of pJP# vectors that includes puroR, blastR, hygR vectors made by J. Pearlberg at HIP
Size (bp): 7894
Parent Vector: None
Empty Vector: None
Properties: Creator, acceptor (destination), loxP, mammalian expression, mammalian transduction, retroviral vector
Author Name: Ed Harlow
Joseph Pearlberg
Publications: None
Vector Map:         Vector Sequence:
Sequence:

 



Vector Features:

Type Name Description Start Position End Position
bacterial origin ori bacterial origin of replication 5659 6341
gene fragment gag/pol/env non-functional gag/pol/env for packaging efficiency 1871 2644
primer JPO113 forward sequencing primer: GCGGTTTTGGCAGTACATCAATGGGCG 3555 3581
primer site PBSQ primer binding sequence (glutamine tRNA primer binding site) 1140 1156
promoter bacterial bacterial promoter (for chlR ORF in Creator-type inserts) 3879 4005
recombination site LoxP LoxP site for recombinational cloning 3651 3684
selectable marker AmpR ampicillin resistance gene (beta-lactamase) 6237 7094
viral LTR 5p LTR 5p viral LTR (MPSV U3, R, U5) 550 1139
viral LTR 3p LTR 3p viral LTR (MPSV U3, R, U5) 3962 4551

 

  • Gene
  • Pathways
  • Protein
  • Clone
  • Organism
  • Genome
  • Reagents

Gene

 

Gene Symbol : GRB7
Symbol Nomenclature : GRB7
Designation : B47|GRB7 adapter protein|epidermal growth factor receptor GRB-7
Full Nomenclature : growth factor receptor-bound protein 7
GENEID : 2886
HGNC : 4567
MIM : 601522
Vega : OTTHUMG00000133253
Target GenBank: BC006535

 

Reference Sequence Alignment

  

HsCD00074508        ------------------------------------------------------------
NM_001030002.2      ------------------------------------------------------------
NM_001242443.1      ------------------------------------------------------------
NM_001242442.1      ATGGGAAAGTGGAGGCCGGGACAAGGGCACACAACTGGTTCCGTTAAGCCCCTCTCTCGC
NM_005310.3         ------------------------------------------------------------
                                                                                

HsCD00074508        ---------ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
NM_001030002.2      ---------ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
NM_001242443.1      ---------ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
NM_001242442.1      TCAGACGCCATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
NM_005310.3         ---------ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
                             ***************************************************

HsCD00074508        TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
NM_001030002.2      TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
NM_001242443.1      TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
NM_001242442.1      TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
NM_005310.3         TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
                    ************************************************************

HsCD00074508        GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
NM_001030002.2      GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
NM_001242443.1      GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
NM_001242442.1      GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
NM_005310.3         GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
                    ************************************************************

HsCD00074508        GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
NM_001030002.2      GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
NM_001242443.1      GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
NM_001242442.1      GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
NM_005310.3         GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
                    ************************************************************

HsCD00074508        CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
NM_001030002.2      CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
NM_001242443.1      CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
NM_001242442.1      CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
NM_005310.3         CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
                    ************************************************************

HsCD00074508        GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
NM_001030002.2      GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
NM_001242443.1      GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
NM_001242442.1      GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
NM_005310.3         GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
                    ************************************************************

HsCD00074508        GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
NM_001030002.2      GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
NM_001242443.1      GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
NM_001242442.1      GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
NM_005310.3         GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
                    ************************************************************

HsCD00074508        TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
NM_001030002.2      TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
NM_001242443.1      TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
NM_001242442.1      TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
NM_005310.3         TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
                    ************************************************************

HsCD00074508        TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
NM_001030002.2      TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
NM_001242443.1      TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
NM_001242442.1      TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
NM_005310.3         TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
                    ************************************************************

HsCD00074508        CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
NM_001030002.2      CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
NM_001242443.1      CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
NM_001242442.1      CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
NM_005310.3         CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
                    ************************************************************

HsCD00074508        CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
NM_001030002.2      CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
NM_001242443.1      CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
NM_001242442.1      CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
NM_005310.3         CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
                    ************************************************************

HsCD00074508        GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
NM_001030002.2      GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
NM_001242443.1      GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
NM_001242442.1      GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
NM_005310.3         GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
                    ************************************************************

HsCD00074508        CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
NM_001030002.2      CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
NM_001242443.1      CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
NM_001242442.1      CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
NM_005310.3         CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
                    ************************************************************

HsCD00074508        CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
NM_001030002.2      CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
NM_001242443.1      CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
NM_001242442.1      CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
NM_005310.3         CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
                    ************************************************************

HsCD00074508        GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
NM_001030002.2      GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
NM_001242443.1      GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
NM_001242442.1      GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
NM_005310.3         GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
                    ************************************************************

HsCD00074508        GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
NM_001030002.2      GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
NM_001242443.1      GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
NM_001242442.1      GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
NM_005310.3         GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
                    ************************************************************

HsCD00074508        TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
NM_001030002.2      TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
NM_001242443.1      TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
NM_001242442.1      TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
NM_005310.3         TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
                    ************************************************************

HsCD00074508        TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
NM_001030002.2      TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
NM_001242443.1      TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
NM_001242442.1      TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
NM_005310.3         TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
                    ************************************************************

HsCD00074508        TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
NM_001030002.2      TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
NM_001242443.1      TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
NM_001242442.1      TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
NM_005310.3         TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
                    ************************************************************

HsCD00074508        TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
NM_001030002.2      TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
NM_001242443.1      TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
NM_001242442.1      TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
NM_005310.3         TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
                    ************************************************************

HsCD00074508        GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
NM_001030002.2      GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
NM_001242443.1      GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
NM_001242442.1      GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
NM_005310.3         GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
                    ************************************************************

HsCD00074508        GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
NM_001030002.2      GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
NM_001242443.1      GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
NM_001242442.1      GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
NM_005310.3         GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
                    ************************************************************

HsCD00074508        CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
NM_001030002.2      CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
NM_001242443.1      CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
NM_001242442.1      CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
NM_005310.3         CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
                    ************************************************************

HsCD00074508        CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
NM_001030002.2      CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
NM_001242443.1      CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
NM_001242442.1      CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
NM_005310.3         CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
                    ************************************************************

HsCD00074508        AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
NM_001030002.2      AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
NM_001242443.1      AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
NM_001242442.1      AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
NM_005310.3         AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
                    ************************************************************

HsCD00074508        GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
NM_001030002.2      GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
NM_001242443.1      GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
NM_001242442.1      GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
NM_005310.3         GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
                    ************************************************************

HsCD00074508        ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTAG
NM_001030002.2      ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTGA
NM_001242443.1      ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTGA
NM_001242442.1      ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTGA
NM_005310.3         ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTGA
                    **********************************************..

Pathways

NCI : Angiopoietin receptor Tie2-mediated signaling
NCI : EPHB forward signaling
NCI : Signaling events mediated by focal adhesion kinase
NCI : Signaling events regulated by Ret tyrosine kinase
Panther : Angiogenesis
Reactome : Cell surface interactions at the vascular wall
Reactome : Downstream signal transduction
Reactome : GRB7 events in ERBB2 signaling
Reactome : Hemostasis
Reactome : Signal Transduction
Reactome : Signaling by ERBB2
Reactome : Signaling by PDGF
Reactome : Signaling by SCF-KIT
Reactome : Tie2 Signaling
WikiPathway : Kit receptor signaling pathway
WikiPathway : angiogenesis overview

Protein

SMART domain : SH2 : Src homology 2 domains
SMART domain : PH : Pleckstrin homology domain.
SMART domain : RA : Ras association (RalGDS/AF-6) domain
UniProt : Q14451
UniProt : Q53YD3
HPRD : 03311

Clone

Cloning Information : 213100
HIP Master Clone ID : 29865
Original Clone ID : FLH213100.01X

Organism


TAX_ID : 9606
Species Specific ID: 2886

Genome

Chromosome : 17
Map Location : 17q12
Ensembl : ENSG00000141738

Reagents

Labome : GRB7-antibody