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GRB7 (Homo sapiens) in pANT7_cGST (GST-tagged in vitro expression vector)

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Explanation of Terms


Gene: Gene Symbol:  GRB7
Gene Name:  growth factor receptor-bound protein 7
Sequence              Map: pANT7_cGST.doc
Original Clone ID: FLH222307.01L
Keyword: None
Species: Homo sapiens
Type: cDNA
Vector Name: pANT7_cGST               Format:  FUSION
Source: HIP
Description: None
Comments: None
Mutation/
Discrepancy :
No / No
Publications: None
Authors:
HsCD00076680

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AVAILABLE
No restriction
Special MTA: None

 

Insert sequence: 1599nts         Open reading frame : 1 to 1599
Reference Sequence Alignment

ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTTTGCCCAGCC
CCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAGGAGGTAAAG
AGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAGGAGAGGCGT
GCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCTCCCTCACAG
AGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGATGCCAGCCGC
CCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAGGTGGCAGCA
GGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCCTTGAGCGAC
GAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGTTTGGAGGAC
CACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGCCGCTTCGTC
TTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCCCTGTTCCCA
GAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAAGACCTCATC
CAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAGCTGCGGGGT
TCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGCCTCTATTAC
TCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGATGTGAACGAG
TCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACTGACTTCGGT
TTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATCTTCTGCAGT
GAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAGTACGGGGTG
CAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCTTGTTTGGGC
TCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTCTCTGGCCAT
GCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAGGAGGCCCAG
GCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCCGGCACGAGC
CTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCCCGTGAGGAG
AGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTCCGGGAGAGT
CAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTGAAGCATTAT
CTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGATGGCCAGACC
CGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGCATCCTGCCG
TGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTTG


Coding Sequence Details
Insert Sequence Verified?: N Verification Method: Insert was fully sequenced in parent vector
Reference Sequence Annotations:
End on reference sequence 1714
Start on reference sequence 116
Mutations:
None
Discrepancy:
None
5' Linker Sequence:
5p GTACAAAAAAGCAGGCTCCACC(atg-goi)

3' Linker Sequence:
5p (goi-stop)GACCCAGCTTTCTTGTAC

 

 Recommended Growth Condition:

Distributed in bacterial strain : DH5-alpha T1 phage resistant
Antibiotic Selection: Host Type:  bacterial    Marker:  ampicillin
Bacterial Selection Condition:  100 ug/mL ampicillin
Growth Condition:  Growth with the single antibiotic in LB at 37 degrees is recommended.
Comments:  Commonly used conditions for ampicillin resistant plasmid clones.
Protein Expression Results: None
Recommended expression in: Not Applicable
       DyNA Vector Map

         Powered by LabGenius

Vector Name: pANT7_cGST

pANT7_cGST in advanced viewed

Synonyms: pANT7-cGST
Sequencing Primer: Forward:  NAP150
Reverse:  NAP138R
Description: with tag/fusion/marker assay, Gateway and reg, acceptor (destination), recombinational cloning clone, in vitro transcription expression with attR1 and NAP150 and ccdB and attR2 and GST and CmR and T7 and NAP138 and ColE and AmpR ampicillin resistance in bacterial
Comments: One in a series of pANT7 vectors made by A. Lau and N. Ramachandran for use with NAPPA arrays. Can be used for cell free expression of the gene insert using human IVTT from Thermo Fisher or rabbit reticulocyte systems
Size (bp): 5964
Parent Vector: None
Empty Vector: EvNO00023103
Properties: Gateway, acceptor (destination), in vitro transcription, recombinational cloning, with tag/fusion/marker
Author Name: Al Lau
Niroshan Ramachandran
Joshua LaBaer
Publications: PMID: 15232106
Title: Self-assembling protein microarrays

Vector Map:         Vector Sequence:
Sequence:

 



Vector Features:

Type Name Description Start Position End Position
bacterial origin ColE ColE1 bacterial origin of replication 3931 3249
death cassette ccdB ccdB death cassette present in 'empty vector' form only (replace with gene of interest) 1876 2085
primer NAP138 NAP138 reverse sequencing primer 5? TGTTTCGCCATTTATCACCTTC 3? 2405 2384
primer NAP150 Forward sequencing primer NAP150 5?-CCC ATT GTA TGG GAT CTG ATC-3? 388 408
promoter T7 T7 transcriptional start sequence 5940 5964
recombination site attR2 AttR2 site for recombination in empty vector 2236 2251
recombination site attR1 AttR1 site for recombination in empty vector 549 565
selectable marker CmR chloramphenicol resistance 782 1438
selectable marker AmpR ampicillin resistance gene 4688 4029
tag GST Glutathione transferase (GST) tag 2282 2950

 

  • Gene
  • Pathways
  • Protein
  • Clone
  • Organism
  • Genome
  • Reagents

Gene

 

Gene Symbol : GRB7
Symbol Nomenclature : GRB7
Designation : B47|GRB7 adapter protein|epidermal growth factor receptor GRB-7
Full Nomenclature : growth factor receptor-bound protein 7
GENEID : 2886
HGNC : 4567
MIM : 601522
Vega : OTTHUMG00000133253
Target GenBank: BC006535

 

Reference Sequence Alignment

  

HsCD00076680        ------------------------------------------------------------
NM_001030002.2      ------------------------------------------------------------
NM_001242443.1      ------------------------------------------------------------
NM_001242442.1      ATGGGAAAGTGGAGGCCGGGACAAGGGCACACAACTGGTTCCGTTAAGCCCCTCTCTCGC
NM_005310.3         ------------------------------------------------------------
                                                                                

HsCD00076680        ---------ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
NM_001030002.2      ---------ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
NM_001242443.1      ---------ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
NM_001242442.1      TCAGACGCCATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
NM_005310.3         ---------ATGGAGCTGGATCTGTCTCCACCTCATCTTAGCAGCTCTCCGGAAGACCTT
                             ***************************************************

HsCD00076680        TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
NM_001030002.2      TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
NM_001242443.1      TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
NM_001242442.1      TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
NM_005310.3         TGCCCAGCCCCTGGGACCCCTCCTGGGACTCCCCGGCCCCCTGATACCCCTCTGCCTGAG
                    ************************************************************

HsCD00076680        GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
NM_001030002.2      GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
NM_001242443.1      GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
NM_001242442.1      GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
NM_005310.3         GAGGTAAAGAGGTCCCAGCCTCTCCTCATCCCAACCACCGGCAGGAAACTTCGAGAGGAG
                    ************************************************************

HsCD00076680        GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
NM_001030002.2      GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
NM_001242443.1      GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
NM_001242442.1      GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
NM_005310.3         GAGAGGCGTGCCACCTCCCTCCCCTCTATCCCCAACCCCTTCCCTGAGCTCTGCAGTCCT
                    ************************************************************

HsCD00076680        CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
NM_001030002.2      CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
NM_001242443.1      CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
NM_001242442.1      CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
NM_005310.3         CCCTCACAGAGCCCAATTCTCGGGGGCCCCTCCAGTGCAAGGGGGCTGCTCCCCCGCGAT
                    ************************************************************

HsCD00076680        GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
NM_001030002.2      GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
NM_001242443.1      GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
NM_001242442.1      GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
NM_005310.3         GCCAGCCGCCCCCATGTAGTAAAGGTGTACAGTGAGGATGGGGCCTGCAGGTCTGTGGAG
                    ************************************************************

HsCD00076680        GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
NM_001030002.2      GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
NM_001242443.1      GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
NM_001242442.1      GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
NM_005310.3         GTGGCAGCAGGTGCCACAGCTCGCCACGTGTGTGAAATGCTGGTGCAGCGAGCTCACGCC
                    ************************************************************

HsCD00076680        TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
NM_001030002.2      TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
NM_001242443.1      TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
NM_001242442.1      TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
NM_005310.3         TTGAGCGACGAGACCTGGGGGCTGGTGGAGTGCCACCCCCACCTAGCACTGGAGCGGGGT
                    ************************************************************

HsCD00076680        TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
NM_001030002.2      TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
NM_001242443.1      TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
NM_001242442.1      TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
NM_005310.3         TTGGAGGACCACGAGTCCGTGGTGGAAGTGCAGGCTGCCTGGCCCGTGGGCGGAGATAGC
                    ************************************************************

HsCD00076680        CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
NM_001030002.2      CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
NM_001242443.1      CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
NM_001242442.1      CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
NM_005310.3         CGCTTCGTCTTCCGGAAAAACTTCGCCAAGTACGAACTGTTCAAGAGCTCCCCACACTCC
                    ************************************************************

HsCD00076680        CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
NM_001030002.2      CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
NM_001242443.1      CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
NM_001242442.1      CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
NM_005310.3         CTGTTCCCAGAAAAAATGGTCTCCAGCTGTCTCGATGCACACACTGGTATATCCCATGAA
                    ************************************************************

HsCD00076680        GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
NM_001030002.2      GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
NM_001242443.1      GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
NM_001242442.1      GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
NM_005310.3         GACCTCATCCAGAACTTCCTGAATGCTGGCAGCTTTCCTGAGATCCAGGGCTTTCTGCAG
                    ************************************************************

HsCD00076680        CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
NM_001030002.2      CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
NM_001242443.1      CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
NM_001242442.1      CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
NM_005310.3         CTGCGGGGTTCAGGACGGAAGCTTTGGAAACGCTTTTTCTGCTTCTTGCGCCGATCTGGC
                    ************************************************************

HsCD00076680        CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
NM_001030002.2      CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
NM_001242443.1      CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
NM_001242442.1      CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
NM_005310.3         CTCTATTACTCCACCAAGGGCACCTCTAAGGATCCGAGGCACCTGCAGTACGTGGCAGAT
                    ************************************************************

HsCD00076680        GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
NM_001030002.2      GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
NM_001242443.1      GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
NM_001242442.1      GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
NM_005310.3         GTGAACGAGTCCAACGTGTACGTGGTGACGCAGGGCCGCAAGCTCTACGGGATGCCCACT
                    ************************************************************

HsCD00076680        GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
NM_001030002.2      GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
NM_001242443.1      GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
NM_001242442.1      GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
NM_005310.3         GACTTCGGTTTCTGTGTCAAGCCCAACAAGCTTCGAAATGGCCACAAGGGGCTTCGGATC
                    ************************************************************

HsCD00076680        TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
NM_001030002.2      TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
NM_001242443.1      TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
NM_001242442.1      TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
NM_005310.3         TTCTGCAGTGAAGATGAGCAGAGCCGCACCTGCTGGCTGGCTGCCTTCCGCCTCTTCAAG
                    ************************************************************

HsCD00076680        TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
NM_001030002.2      TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
NM_001242443.1      TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
NM_001242442.1      TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
NM_005310.3         TACGGGGTGCAGCTGTACAAGAATTACCAGCAGGCACAGTCTCGCCATCTGCATCCATCT
                    ************************************************************

HsCD00076680        TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
NM_001030002.2      TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
NM_001242443.1      TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
NM_001242442.1      TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
NM_005310.3         TGTTTGGGCTCCCCACCCTTGAGAAGTGCCTCAGATAATACCCTGGTGGCCATGGACTTC
                    ************************************************************

HsCD00076680        TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
NM_001030002.2      TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
NM_001242443.1      TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
NM_001242442.1      TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
NM_005310.3         TCTGGCCATGCTGGGCGTGTCATTGAGAACCCCCGGGAGGCTCTGAGTGTGGCCCTGGAG
                    ************************************************************

HsCD00076680        GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
NM_001030002.2      GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
NM_001242443.1      GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
NM_001242442.1      GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
NM_005310.3         GAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGCCTCAGCCTGCCCATGCCAGCCTCC
                    ************************************************************

HsCD00076680        GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
NM_001030002.2      GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
NM_001242443.1      GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
NM_001242442.1      GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
NM_005310.3         GGCACGAGCCTCAGTGCAGCCATCCACCGCACCCAACTCTGGTTCCACGGGCGCATTTCC
                    ************************************************************

HsCD00076680        CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
NM_001030002.2      CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
NM_001242443.1      CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
NM_001242442.1      CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
NM_005310.3         CGTGAGGAGAGCCAGCGGCTTATTGGACAGCAGGGCTTGGTAGACGGCCTGTTCCTGGTC
                    ************************************************************

HsCD00076680        CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
NM_001030002.2      CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
NM_001242443.1      CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
NM_001242442.1      CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
NM_005310.3         CGGGAGAGTCAGCGGAACCCCCAGGGCTTTGTCCTCTCTTTGTGCCACCTGCAGAAAGTG
                    ************************************************************

HsCD00076680        AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
NM_001030002.2      AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
NM_001242443.1      AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
NM_001242442.1      AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
NM_005310.3         AAGCATTATCTCATCCTGCCGAGCGAGGAGGAGGGCCGCCTGTACTTCAGCATGGATGAT
                    ************************************************************

HsCD00076680        GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
NM_001030002.2      GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
NM_001242443.1      GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
NM_001242442.1      GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
NM_005310.3         GGCCAGACCCGCTTCACTGACCTGCTGCAGCTCGTGGAGTTCCACCAGCTGAACCGCGGC
                    ************************************************************

HsCD00076680        ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTTG
NM_001030002.2      ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTGA
NM_001242443.1      ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTGA
NM_001242442.1      ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTGA
NM_005310.3         ATCCTGCCGTGCTTGCTGCGCCATTGCTGCACGCGGGTGGCCCTCTGA
                    ********************************************** .

Pathways

NCI : Angiopoietin receptor Tie2-mediated signaling
NCI : EPHB forward signaling
NCI : Signaling events mediated by focal adhesion kinase
NCI : Signaling events regulated by Ret tyrosine kinase
Panther : Angiogenesis
Reactome : Cell surface interactions at the vascular wall
Reactome : Downstream signal transduction
Reactome : GRB7 events in ERBB2 signaling
Reactome : Hemostasis
Reactome : Signal Transduction
Reactome : Signaling by ERBB2
Reactome : Signaling by PDGF
Reactome : Signaling by SCF-KIT
Reactome : Tie2 Signaling
WikiPathway : Kit receptor signaling pathway
WikiPathway : angiogenesis overview

Protein

SMART domain : SH2 : Src homology 2 domains
SMART domain : PH : Pleckstrin homology domain.
SMART domain : RA : Ras association (RalGDS/AF-6) domain
UniProt : Q14451
UniProt : Q53YD3
HPRD : 03311

Clone

Cloning Information : 222307
HIP Master Clone ID : 138197
Original Clone ID : FLH222307.01L

Organism


TAX_ID : 9606
Species Specific ID: 2886

Genome

Chromosome : 17
Map Location : 17q12
Ensembl : ENSG00000141738

Reagents

Labome : GRB7-antibody