DNASU Plasmid | JUN (Homo sapiens) in pDONR221 (Gateway donor/master vector)

Explanation of Terms

Gene:

Gene Symbol: JUN

Gene Name: jun proto-oncogene

Original Clone ID:

Jun_pDONR221_Fusion

Keyword:

None

Species:

Homo sapiens

Type:

cDNA

Vector Name:

pDONR221

Format:

FUSION

Source:

Center for Personalized Diagnostics

Description:

None

Comments:

None

Mutation / Discrepancy:

No / No

Publications:

None

Authors:

Center for Personalized Diagnostics
Brianne Petritis

HsCD00520171

Price:

AVAILABLE

No restriction
Special MTA: None

Insert Sequence
Protein Sequence

Insert sequence: 996nts

Open reading frame: 1 to 996

Reference Sequence Alignment

ATGACTGCAAAGATGGAAACGACCTTCTATGACGATGCCCTCAACGCCTCGTTCCTCCCG
TCCGAGAGCGGACCTTATGGCTACAGTAACCCCAAGATCCTGAAACAGAGCATGACCCTG
AACCTGGCCGACCCAGTGGGGAGCCTGAAGCCGCACCTCCGCGCCAAGAACTCGGACCTC
CTCACCTCGCCCGACGTGGGGCTGCTCAAGCTGGCGTCGCCCGAGCTGGAGCGCCTGATA
ATCCAGTCCAGCAACGGGCACATCACCACCACGCCGACCCCCACCCAGTTCCTGTGCCCC
AAGAACGTGACAGATGAGCAGGAGGGCTTCGCCGAGGGCTTCGTGCGCGCCCTGGCCGAA
CTGCACAGCCAGAACACGCTGCCCAGCGTCACGTCGGCGGCGCAGCCGGTCAACGGGGCA
GGCATGGTGGCTCCCGCGGTAGCCTCGGTGGCAGGGGGCAGCGGCAGCGGCGGCTTCAGC
GCCAGCCTGCACAGCGAGCCGCCGGTCTACGCAAACCTCAGCAACTTCAACCCAGGCGCG
CTGAGCAGCGGCGGCGGGGCGCCCTCCTACGGCGCGGCCGGCCTGGCCTTTCCCGCGCAA
CCCCAGCAGCAGCAGCAGCCGCCGCACCACCTGCCCCAGCAGATGCCCGTGCAGCACCCG
CGGCTGCAGGCCCTGAAGGAGGAGCCTCAGACAGTGCCCGAGATGCCCGGCGAGACACCG
CCCCTGTCCCCCATCGACATGGAGTCCCAGGAGCGGATCAAGGCGGAGAGGAAGCGCATG
AGGAACCGCATCGCTGCCTCCAAGTGCCGAAAAAGGAAGCTGGAGAGAATCGCCCGGCTG
GAGGAAAAAGTGAAAACCTTGAAAGCTCAGAACTCGGAGCTGGCGTCCACGGCCAACATG
CTCAGGGAACAGGTGGCACAGCTTAAACAGAAAGTCATGAACCACGTTAACAGTGGGTGC
CAACTCATGCTAACGCAGCAGTTGCAAACATTTTTG

Protein sequence predicted based on nucleotide sequence

MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDL
LTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAE
LHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGA
LSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETP
PLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANM
LREQVAQLKQKVMNHVNSGCQLMLTQQLQTFL

Coding Sequence Details

Insert Sequence Verified?:

Verification Method:

Sequence Verification

Mutations:

None

Discrepancy:

None

5' Linker Sequence:

None

3' Linker Sequence:

None

Recommended Growth Condition:

Distributed in bacterial strain:

DH5-alpha T1 phage resistant

Antibiotic Selection:

Host Type: bacterial Marker: kanamycin

Bacterial Selection Condition: 50ug/mL kanamycin

Growth Condition: Growth with the single antibiotic in LB at 37 degrees is recommended.

Comments: Conditions for Gateway-type vectors in recombined (with insert) form and other kanamycin resistant vectors.

Protein Expression Results:

None

Recommended expression in:

Not Applicable

Vector Name:

pDONR221

Synonyms:

Sequencing Primer:

Forward: U19

Reverse: AttP2

Description:

Gateway®, donor (entry), recombinational cloning clone, bacterial expression expression with rrnB T2 and rrnB T1 and M13 forward and attP1 and ccdB and CmR and cat_promoter-var002 and attP2 and T7 promoter and M13 reverse and KanR and ori; 50ug/mL of Kanamycin resistance in Pichia;

Comments:

The position of features were determined for the unrecombined (empty) form of the vector, which is described in detail on the Invitrogen website.

Size (bp):

4762

Parent Vector:

None

Properties:

Gateway, bacterial expression, donor (entry), recombinational cloning

Author Name:

Invitrogen

Publications:

None

Vector Map:

Vector Sequence:

Sequence:

CTTTCCTGCGTTATCCCCTGATTCTGTGGATAACCGTATTACCGCCTTTGAGTGAGCTGATACCGCTCGCCGCAGCCGAACGACCGAGCGCAGCGAGTCAGTGAGCGAGGAAGCGGAAGAGCGCCCAATACGCAAACCGCCTCTCCCCGCGCGTTGGCCGATTCATTAATGCAGCTGGCACGACAGGTTTCCCGACTGGAAAGCGGGCAGTGAGCGCAACGCAATTAATACGCGTACCGCTAGCCAGGAAGAGTTTGTAGAAACGCAAAAAGGCCATCCGTCAGGATGGCCTTCTGCTTAGTTTGATGCCTGGCAGTTTATGGCGGGCGTCCTGCCCGCCACCCTCCGGGCCGTTGCTTCACAACGTTCAAATCCGCTCCCGGCGGATTTGTCCTACTCAGGAGAGCGTTCACCGACAAACAACAGATAAAACGAAAGGCCCAGTCTTCCGACTGAGCCTTTCGTTTTATTTGATGCCTGGCAGTTCCCTACTCTCGCGTTAACGCTAGCATGGATGTTTTCCCAGTCACGACGTTGTAAAACGACGGCCAGTCTTAAGCTCGGGCCCCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACACATTGATGAGCAATGCTTTTTTATAATGCCAACTTTGTACAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATCCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAGTCGACCGACAGCCTTCCAAATGTTCTTCGGGTGATGCTGCCAACTTAGTCGACCGACAGCCTTCCAAATGTTCTTCTCAAACGGAATCGTCGTATCCAGCCTACTCGCTATTGTCCTCAATGCCGTATTAAATCATAAAAAGAAATAAGAAAAAGAGGTGCGAGCCTCTTTTTTGTGTGACAAAATAAAAACATCTACCTATTCATATACGCTAGTGTCATAGTCCTGAAAATCATCTGCATCAAGAACAATTTCACAACTCTTATACTTTTCTCTTACAAGTCGTTCGGCTTCATCTGGATTTTCAGCCTCTATACTTACTAAACGTGATAAAGTTTCTGTAATTTCTACTGTATCGACCTGCAGACTGGCTGTGTATAAGGGAGCCTGACATTTATATTCCCCAGAACATCAGGTTAATGGCGTTTTTGATGTCATTTTCGCGGTGGCTGAGATCAGCCACTTCTTCCCCGATAACGGAGACCGGCACACTGGCCATATCGGTGGTCATCATGCGCCAGCTTTCATCCCCGATATGCACCACCGGGTAAAGTTCACGGGAGACTTTATCTGACAGCAGACGTGCACTGGCCAGGGGGATCACCATCCGTCGCCCGGGCGTGTCAATAATATCACTCTGTACATCCACAAACAGACGATAACGGCTCTCTCTTTTATAGGTGTAAACCTTAAACTGCATTTCACCAGCCCCTGTTCTCGTCAGCAAAAGAGCCGTTCATTTCAATAAACCGGGCGACCTCAGCCATCCCTTCCTGATTTTCCGCTTTCCAGCGTTCGGCACGCAGACGACGGGCTTCATTCTGCATGGTTGTGCTTACCAGACCGGAGATATTGACATCATATATGCCTTGAGCAACTGATAGCTGTCGCTGTCAACTGTCACTGTAATACGCTGCTTCATAGCATACCTCTTTTTGACATACTTCGGGTATACATATCAGTATATATTCTTATACCGCAAAAATCAGCGCGCAAATACGCATACTGTTATCTGGCTTTTAGTAAGCCGGATCCACGCGGCGTTTACGCCCCGCCCTGCCACTCATCGCAGTACTGTTGTAATTCATTAAGCATTCTGCCGACATGGAAGCCATCACAGACGGCATGATGAACCTGAATCGCCAGCGGCATCAGCACCTTGTCGCCTTGCGTATAATATTTGCCCATGGTGAAAACGGGGGCGAAGAAGTTGTCCATATTGGCCACGTTTAAATCAAAACTGGTGAAACTCACCCAGGGATTGGCTGAGACGAAAAACATATTCTCAATAAACCCTTTAGGGAAATAGGCCAGGTTTTCACCGTAACACGCCACATCTTGCGAATATATGTGTAGAAACTGCCGGAAATCGTCGTGGTATTCACTCCAGAGCGATGAAAACGTTTCAGTTTGCTCATGGAAAACGGTGTAACAAGGGTGAACACTATCCCATATCACCAGCTCACCGTCTTTCATTGCCATACGGAATTCCGGATGAGCATTCATCAGGCGGGCAAGAATGTGAATAAAGGCCGGATAAAACTTGTGCTTATTTTTCTTTACGGTCTTTAAAAAGGCCGTAATATCCAGCTGAACGGTCTGGTTATAGGTACATTGAGCAACTGACTGAAATGCCTCAAAATGTTCTTTACGATGCCATTGGGATATATCAACGGTGGTATATCCAGTGATTTTTTTCTCCATTTTAGCTTCCTTAGCTCCTGAAAATCTCGATAACTCAAAAAATACGCCCGGTAGTGATCTTATTTCATTATGGTGAAAGTTGGAACCTCTTACGTGCCGATCAACGTCTCATTTTCGCCAAAAGTTGGCCCAGGGCTTCCCGGTATCAACAGGGACACCAGGATTTATTTATTCTGCGAAGTGATCTTCCGTCACAGGTATTTATTCGGCGCAAAGTGCGTCGGGTGATGCTGCCAACTTAGTCGACTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGGATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTCTTGTACAAAGTTGGCATTATAAGAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGCCATCCAGCTGATATCCCCTATAGTGAGTCGTATTACATGGTCATAGCTGTTTCCTGGCAGCTCTGGCCCGTGTCTCAAAATCTCTGATGTTACATTGCACAAGATAAAATAATATCATCATGAACAATAAAACTGTCTGCTTACATAAACAGTAATACAAGGGGTGTTATGAGCCATATTCAACGGGAAACGTCGAGGCCGCGATTAAATTCCAACATGGATGCTGATTTATATGGGTATAAATGGGCTCGCGATAATGTCGGGCAATCAGGTGCGACAATCTATCGCTTGTATGGGAAGCCCGATGCGCCAGAGTTGTTTCTGAAACATGGCAAAGGTAGCGTTGCCAATGATGTTACAGATGAGATGGTCAGACTAAACTGGCTGACGGAATTTATGCCTCTTCCGACCATCAAGCATTTTATCCGTACTCCTGATGATGCATGGTTACTCACCACTGCGATCCCCGGAAAAACAGCATTCCAGGTATTAGAAGAATATCCTGATTCAGGTGAAAATATTGTTGATGCGCTGGCAGTGTTCCTGCGCCGGTTGCATTCGATTCCTGTTTGTAATTGTCCTTTTAACAGCGATCGCGTATTTCGTCTCGCTCAGGCGCAATCACGAATGAATAACGGTTTGGTTGATGCGAGTGATTTTGATGACGAGCGTAATGGCTGGCCTGTTGAACAAGTCTGGAAAGAAATGCATAAACTTTTGCCATTCTCACCGGATTCAGTCGTCACTCATGGTGATTTCTCACTTGATAACCTTATTTTTGACGAGGGGAAATTAATAGGTTGTATTGATGTTGGACGAGTCGGAATCGCAGACCGATACCAGGATCTTGCCATCCTATGGAACTGCCTCGGTGAGTTTTCTCCTTCATTACAGAAACGGCTTTTTCAAAAATATGGTATTGATAATCCTGATATGAATAAATTGCAGTTTCATTTGATGCTCGATGAGTTTTTCTAATCAGAATTGGTTAATTGGTTGTAACACTGGCAGAGCATTACGCTGACTTGACGGGACGGCGCAAGCTCATGACCAAAATCCCTTAACGTGAGTTACGCGTCGTTCCACTGAGCGTCAGACCCCGTAGAAAAGATCAAAGGATCTTCTTGAGATCCTTTTTTTCTGCGCGTAATCTGCTGCTTGCAAACAAAAAAACCACCGCTACCAGCGGTGGTTTGTTTGCCGGATCAAGAGCTACCAACTCTTTTTCCGAAGGTAACTGGCTTCAGCAGAGCGCAGATACCAAATACTGTTCTTCTAGTGTAGCCGTAGTTAGGCCACCACTTCAAGAACTCTGTAGCACCGCCTACATACCTCGCTCTGCTAATCCTGTTACCAGTGGCTGCTGCCAGTGGCGATAAGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACGGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACTGAGATACCTACAGCGTGAGCTATGAGAAAGCGCCACGCTTCCCGAAGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGCGCACGAGGGAGCTTCCAGGGGGAAACGCCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGACTTGAGCGTCGATTTTTGTGATGCTCGTCAGGGGGGCGGAGCCTATGGAAAAACGCCAGCAACGCGGCCTTTTTACGGTTCCTGGCCTTTTGCTGGCCTTTTGCTCACATGTT

Vector Features:

Type

Name

Description

Start

End

CDS

ccdB

CcdB, a bacterial toxin that poisons DNA gyrase

1197

1502

CDS

CmR

confers resistance to chloramphenicol

1847

2506

CDS

KanR

confers resistance to kanamycin in bacteria or G418 (Geneticin) in eukaryotes

3156

3965

Terminator

rrnB T2

transcription terminator T2 from the E. coli rrnB gene

268

295

Terminator

rrnB T1

transcription terminator T1 from the E. coli rrnB gene

387

473

primer_bind

M13 forward

common sequencing primer, one of multiple similar variants

537

553

primer_bind

M13 reverse

common sequencing primer, one of multiple similar variants

3027

3043

promoter

cat_promoter-var002

promoter of the E. coli cat gene encoding chloramphenicol acetyltransferase

2507

2609

promoter

T7 promoter

promoter for bacteriophage T7 RNA polymerase

3004

3022

protein binding site

attP1

recombination site for the Gateway BP reaction

570

801

protein binding site

attP2

recombination site for the Gateway BP reaction

2754

2985

rep_origin

ori

high-copy-number ColE1/pMB1/pBR322/pUC origin of replication

4112

4700

Gene

Gene Symbol :

JUN

Symbol Nomenclature :

JUN

SYNONYM :

AP-1; AP1; c-Jun

Designation :

Full Nomenclature :

jun proto-oncogene

GENEID :

3725

GenBank Accession :

BC006175

HGNC :

6204

MIM :

165160

Vega :

OTTHUMG00000008376

Target GenBank:

BC006175

Reference Sequence Alignment

  

HsCD00520171      ATGACTGCAAAGATGGAAACGACCTTCTATGACGATGCCCTCAACGCCTCGTTCCTCCCG
NM_002228.3       ATGACTGCAAAGATGGAAACGACCTTCTATGACGATGCCCTCAACGCCTCGTTCCTCCCG
                  ************************************************************

HsCD00520171      TCCGAGAGCGGACCTTATGGCTACAGTAACCCCAAGATCCTGAAACAGAGCATGACCCTG
NM_002228.3       TCCGAGAGCGGACCTTATGGCTACAGTAACCCCAAGATCCTGAAACAGAGCATGACCCTG
                  ************************************************************

HsCD00520171      AACCTGGCCGACCCAGTGGGGAGCCTGAAGCCGCACCTCCGCGCCAAGAACTCGGACCTC
NM_002228.3       AACCTGGCCGACCCAGTGGGGAGCCTGAAGCCGCACCTCCGCGCCAAGAACTCGGACCTC
                  ************************************************************

HsCD00520171      CTCACCTCGCCCGACGTGGGGCTGCTCAAGCTGGCGTCGCCCGAGCTGGAGCGCCTGATA
NM_002228.3       CTCACCTCGCCCGACGTGGGGCTGCTCAAGCTGGCGTCGCCCGAGCTGGAGCGCCTGATA
                  ************************************************************

HsCD00520171      ATCCAGTCCAGCAACGGGCACATCACCACCACGCCGACCCCCACCCAGTTCCTGTGCCCC
NM_002228.3       ATCCAGTCCAGCAACGGGCACATCACCACCACGCCGACCCCCACCCAGTTCCTGTGCCCC
                  ************************************************************

HsCD00520171      AAGAACGTGACAGATGAGCAGGAGGGCTTCGCCGAGGGCTTCGTGCGCGCCCTGGCCGAA
NM_002228.3       AAGAACGTGACAGATGAGCAGGAGGGCTTCGCCGAGGGCTTCGTGCGCGCCCTGGCCGAA
                  ************************************************************

HsCD00520171      CTGCACAGCCAGAACACGCTGCCCAGCGTCACGTCGGCGGCGCAGCCGGTCAACGGGGCA
NM_002228.3       CTGCACAGCCAGAACACGCTGCCCAGCGTCACGTCGGCGGCGCAGCCGGTCAACGGGGCA
                  ************************************************************

HsCD00520171      GGCATGGTGGCTCCCGCGGTAGCCTCGGTGGCAGGGGGCAGCGGCAGCGGCGGCTTCAGC
NM_002228.3       GGCATGGTGGCTCCCGCGGTAGCCTCGGTGGCAGGGGGCAGCGGCAGCGGCGGCTTCAGC
                  ************************************************************

HsCD00520171      GCCAGCCTGCACAGCGAGCCGCCGGTCTACGCAAACCTCAGCAACTTCAACCCAGGCGCG
NM_002228.3       GCCAGCCTGCACAGCGAGCCGCCGGTCTACGCAAACCTCAGCAACTTCAACCCAGGCGCG
                  ************************************************************

HsCD00520171      CTGAGCAGCGGCGGCGGGGCGCCCTCCTACGGCGCGGCCGGCCTGGCCTTTCCCGCGCAA
NM_002228.3       CTGAGCAGCGGCGGCGGGGCGCCCTCCTACGGCGCGGCCGGCCTGGCCTTTCCCGCGCAA
                  ************************************************************

HsCD00520171      CCCCAGCAGCAGCAGCAGCCGCCGCACCACCTGCCCCAGCAGATGCCCGTGCAGCACCCG
NM_002228.3       CCCCAGCAGCAGCAGCAGCCGCCGCACCACCTGCCCCAGCAGATGCCCGTGCAGCACCCG
                  ************************************************************

HsCD00520171      CGGCTGCAGGCCCTGAAGGAGGAGCCTCAGACAGTGCCCGAGATGCCCGGCGAGACACCG
NM_002228.3       CGGCTGCAGGCCCTGAAGGAGGAGCCTCAGACAGTGCCCGAGATGCCCGGCGAGACACCG
                  ************************************************************

HsCD00520171      CCCCTGTCCCCCATCGACATGGAGTCCCAGGAGCGGATCAAGGCGGAGAGGAAGCGCATG
NM_002228.3       CCCCTGTCCCCCATCGACATGGAGTCCCAGGAGCGGATCAAGGCGGAGAGGAAGCGCATG
                  ************************************************************

HsCD00520171      AGGAACCGCATCGCTGCCTCCAAGTGCCGAAAAAGGAAGCTGGAGAGAATCGCCCGGCTG
NM_002228.3       AGGAACCGCATCGCTGCCTCCAAGTGCCGAAAAAGGAAGCTGGAGAGAATCGCCCGGCTG
                  ************************************************************

HsCD00520171      GAGGAAAAAGTGAAAACCTTGAAAGCTCAGAACTCGGAGCTGGCGTCCACGGCCAACATG
NM_002228.3       GAGGAAAAAGTGAAAACCTTGAAAGCTCAGAACTCGGAGCTGGCGTCCACGGCCAACATG
                  ************************************************************

HsCD00520171      CTCAGGGAACAGGTGGCACAGCTTAAACAGAAAGTCATGAACCACGTTAACAGTGGGTGC
NM_002228.3       CTCAGGGAACAGGTGGCACAGCTTAAACAGAAAGTCATGAACCACGTTAACAGTGGGTGC
                  ************************************************************

HsCD00520171      CAACTCATGCTAACGCAGCAGTTGCAAACATTTTTG
NM_002228.3       CAACTCATGCTAACGCAGCAGTTGCAAACATTTTGA
                  ********************************** .

Pathways

NCI :

AP-1 transcription factor network

NCI :

ATF-2 transcription factor network

NCI :

BCR signaling pathway

NCI :

Calcineurin-regulated NFAT-dependent transcription in lymphocytes

NCI :

Calcium signaling in the CD4+ TCR pathway

NCI :

CD40/CD40L signaling

NCI :

CDC42 signaling events

NCI :

Direct p53 effectors

NCI :

Downstream signaling in naïve CD8+ T cells

NCI :

Endothelins

NCI :

ErbB1 downstream signaling

NCI :

ErbB2/ErbB3 signaling events

NCI :

Fc-epsilon receptor I signaling in mast cells

NCI :

FGF signaling pathway

NCI :

FOXA1 transcription factor network

NCI :

Glucocorticoid receptor regulatory network

NCI :

HIF-1-alpha transcription factor network

NCI :

IL1-mediated signaling events

NCI :

IL12 signaling mediated by STAT4

NCI :

IL2-mediated signaling events

NCI :

IL6-mediated signaling events

NCI :

Integrin-linked kinase signaling

NCI :

JNK signaling in the CD4+ TCR pathway

NCI :

LPA receptor mediated events

NCI :

Nephrin/Neph1 signaling in the kidney podocyte

NCI :

Osteopontin-mediated events

NCI :

PDGFR-alpha signaling pathway

NCI :

PDGFR-beta signaling pathway

NCI :

Presenilin action in Notch and Wnt signaling

NCI :

RAC1 signaling pathway

NCI :

Regulation of Androgen receptor activity

NCI :

Regulation of nuclear beta catenin signaling and target gene transcription

NCI :

Regulation of nuclear SMAD2/3 signaling

NCI :

Regulation of retinoblastoma protein

NCI :

Regulation of Telomerase

NCI :

RhoA signaling pathway

NCI :

S1P2 pathway

NCI :

Signaling events mediated by focal adhesion kinase

NCI :

Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

NCI :

Signaling events regulated by Ret tyrosine kinase

NCI :

Signaling mediated by p38-alpha and p38-beta

NCI :

Validated nuclear estrogen receptor alpha network

NCI :

Validated transcriptional targets of AP1 family members Fra1 and Fra2

Panther :

Angiogenesis

Panther :

Apoptosis signaling pathway

Panther :

B cell activation

Panther :

FAS signaling pathway

Panther :

Huntington disease

Panther :

Inflammation mediated by chemokine and cytokine signaling pathway

Panther :

Oxidative stress response

Panther :

PDGF signaling pathway

Panther :

Ras Pathway

Panther :

T cell activation

Panther :

TGF-beta signaling pathway

Panther :

Toll receptor signaling pathway

Reactome :

Activated TLR4 signalling

Reactome :

Activation of the AP-1 family of transcription factors

Reactome :

Cellular responses to stress

Reactome :

Cellular Senescence

Reactome :

Fc epsilon receptor (FCERI) signaling

Reactome :

FCERI mediated MAPK activation

Reactome :

Immune System

Reactome :

Innate Immune System

Reactome :

MAP kinase activation in TLR cascade

Reactome :

MAPK targets/ Nuclear events mediated by MAP kinases

Reactome :

MyD88 cascade initiated on plasma membrane

Reactome :

MyD88 dependent cascade initiated on endosome

Reactome :

MyD88-independent cascade

Reactome :

MyD88:Mal cascade initiated on plasma membrane

Reactome :

Oxidative Stress Induced Senescence

Reactome :

Pre-NOTCH Expression and Processing

Reactome :

Pre-NOTCH Transcription and Translation

Reactome :

Senescence-Associated Secretory Phenotype (SASP)

Reactome :

Signal Transduction

Reactome :

Signaling by NOTCH

Reactome :

Toll Like Receptor 10 (TLR10) Cascade

Reactome :

Toll Like Receptor 2 (TLR2) Cascade

Reactome :

Toll Like Receptor 3 (TLR3) Cascade

Reactome :

Toll Like Receptor 4 (TLR4) Cascade

Reactome :

Toll Like Receptor 5 (TLR5) Cascade

Reactome :

Toll Like Receptor 7/8 (TLR7/8) Cascade

Reactome :

Toll Like Receptor 9 (TLR9) Cascade

Reactome :

Toll Like Receptor TLR1:TLR2 Cascade

Reactome :

Toll Like Receptor TLR6:TLR2 Cascade

Reactome :

Toll-Like Receptors Cascades

Reactome :

TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation

Reactome :

TRAF6 Mediated Induction of proinflammatory cytokines

Reactome :

TRIF-mediated TLR3/TLR4 signaling

WikiPathway :

Androgen receptor signaling pathway

WikiPathway :

Apoptosis

WikiPathway :

Apoptosis Modulation and Signaling

WikiPathway :

B Cell Receptor Signaling Pathway

WikiPathway :

DNA damage response (only ATM dependent)

WikiPathway :

EGF/EGFR Signaling Pathway

WikiPathway :

ErbB signaling pathway

WikiPathway :

Estrogen signaling pathway

WikiPathway :

FAS pathway and Stress induction of HSP regulation

WikiPathway :

Focal Adhesion

WikiPathway :

IL-1 signaling pathway

WikiPathway :

IL-2 Signaling pathway

WikiPathway :

IL-3 Signaling Pathway

WikiPathway :

IL-5 signaling pathway

WikiPathway :

Insulin Signaling

WikiPathway :

Integrated Breast Cancer Pathway

WikiPathway :

MAPK Cascade

WikiPathway :

MAPK signaling pathway

WikiPathway :

Myometrial Relaxation and Contraction Pathways

WikiPathway :

Physiological and Pathological Hypertrophy of the Heart

WikiPathway :

Prolactin Signaling Pathway

WikiPathway :

RANKL/RANK Signaling Pathway

WikiPathway :

Regulation of toll-like receptor signaling pathway

WikiPathway :

Selenium Metabolism and Selenoproteins

WikiPathway :

Senescence and Autophagy

WikiPathway :

Signaling of Hepatocyte Growth Factor Receptor

WikiPathway :

TCR Signaling Pathway

WikiPathway :

TGF Beta Signaling Pathway

WikiPathway :

TGF beta Signaling Pathway

WikiPathway :

TNF alpha Signaling Pathway

WikiPathway :

Toll-like receptor signaling pathway

WikiPathway :

TSH signaling pathway

WikiPathway :

TWEAK Signaling Pathway

WikiPathway :

Wnt Signaling Pathway

WikiPathway :

Wnt Signaling Pathway and Pluripotency

Protein

SMART domain :

BRLZ : basic region leucin zipper

HPRD :

01302

Clone

Cloning Information :

594192

Original Clone ID :

Jun_pDONR221_Fusion

Organism

Species Specific ID:

3725

Genome

Chromosome :

Map Location :

1p32-p31

Ensembl :

ENSG00000177606