DNASU Plasmid | SKIL (H. sapiens )<br>In pSGX3 (His-tagged bacterial expression vector)

Explanation of Terms

Gene:

Gene Symbol: SKIL

Gene Name: SKI-like oncogene

Original Clone ID:

13030a3BCt19p1

Keyword:

full-length cds

Species:

Homo sapiens

Type:

cDNA

Vector Name:

pSGX3

Format:

CLOSED

Source:

New York SGX Research Center for Structural Genomics

Description:

None

Comments:

None

Mutation / Discrepancy:

No / No

Publications:

None

Authors:

PSI
New York SGX Research Center for Structural Genomics

HsCD00531586

Price:

AVAILABLE

No restriction
Special MTA: PSI

Insert Sequence
Protein Sequence

Insert sequence: 2076nts

Open reading frame: 1 to 2076

Reference Sequence Alignment

GAAAACCTGCAAACTAATTTCAGCCTGGTCCAGGGTTCGACAAAAAAACTGAATGGGATG
GGTGATGACGGCAGCCCCCCTGCCAAGAAAATGATAACGGACATTCATGTTAATGGTAAG
ACAATCAATAAGGTGCCAACAGTTAAGAAAGAGCACTTGGATGACTATGGAGAAGCACCA
GTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTGCAT
TTAAATCCCAGTTTGAAACACACATTGGCCCAATTCCATCTGTCGTCTCAATCCTCGCTG
GGTGGACCAGCAGCTTTCAGTGCCCGGCATTCCCAAGAAAGCATGTCGCCTACAGTCTTC
TTGCCACTGCCCAGTCCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTAGTGACTCCTCC
ACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCATGTTTCCAGGTGGGCGGA
GAAAAGAGACTCTGCCTGCCACAGGTATTGAACTCGGTTCTGCGTGAGTTTACTCTGCAA
CAGATCAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCTGATCAG
CTTCATATCTTAAAGGTACTGGGCATTTTGCCTTTCAACGCTCCATCCTGTGGGCTGATT
ACATTAACTGATGCACAACGTCTGTGTAACGCTTTGCTGCGGCCACGAACTTTTCCTCAA
AATGGTAGCGTTTTGCCTGCAAAGTCCTCATTGGCCCAGTTAAAGGAAACTGGCTCGGCA
TTTGAAGTCGAGCATGAATGCCTAGGCAAGTGCCAGGGCCTGTTTGCTCCCCAGTTCTAT
GTACAGCCAGATGCTCCGTGCATCCAGTGTTTGGAGTGTTGTGGAATGTTTGCGCCCCAA
ACTTTTGTGATGCATAGCCACAGATCACCTGACAAACGCACTTGCCACTGGGGCTTTGAA
TCAGCTAAATGGCATTGCTATCTGCATGTTAACCAAAAATACTTGGGCACCCCCGAGGAG
AAGAAATTGAAAATTATTTTAGAGGAAATGAAGGAAAAGTTTTCTATGAGAAGTGGAAAG
AGAAATCAATCCAAGACAGATGCGCCGTCTGGCATGGAATTACAGTCATGGTATCCGGTT
ATTAAGCAGGAAGGTGACCATGTTTCTCAAACTCATTCGTTTTTGCATCCCTCGTATTAC
TTATACATGTGCGACAAAGTGGTGGCTCCCAACGTGTCACTTACCTCTGCTGTTTCCCAG
TCTAAAGAGCTGACAAAAACCGAGGCTAGTAAGTCCATATCCCGTCAGTCTGAAAAAGCT
CATTCTAGTGGCAAGCTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTGGAAGAGCAA
GAAAAAATGGACCTGAAAACAAGTCGCGAATTGTGCAGTCGTTTGGATGCATCCATCTCA
AACAATTCTACATCCAAGCGTAAATCTGAGTCTGCCACTTGCAACCTGGTACGCGATATT
AACAAAGTGGGAATTGGCTTGGTCGCCGCAGCTAGCTCTCCGCTTCTTGTGAAAGATGTC
ATCTGTGAGGATGATAAGGGCAAAATCATGGAAGAGGTCATGAGAACTTATCTGAAACAA
CAAGAGAAACTGAACTTGATTCTGCAAAAGAAACAGCAATTGCAAATGGAGGTCAAAATG
TTGAGTAGTTCAAAATCGATGAAAGAACTGACAGAAGAGCAACAGAATTTGCAAAAGGAG
CTGGAATCTTTGCAGAATGAACACGCACAGCGTATGGAGGAATTTTACGTTGAGCAGAAA
GACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAGAAATGCACATGTGACTCAAATTTA
GAAAAGGATAAAGAAGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTGGAC
CATGCTGAGGCCGATAGGCAAGAACTCCAAGACGAGTTGAGACAGGAACGGGAAGCAAGA
CAGAAGTTAGAGATGATGATAAAAGAGCTGAAATTGCAGATTCTGAAATCATCAAAGACT
GCCAAAGAAGAAGGGCATCATCACCATCACCACTGA

Protein sequence predicted based on nucleotide sequence

ENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHVNGKTINKVPTVKKEHLDDYGEAP
VETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTVF
LPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQ
QINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQ
NGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQ
TFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGK
RNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVSQ
SKELTKTEASKSISRQSEKAHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASIS
NNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQ
QEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQK
DLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREAR
QKLEMMIKELKLQILKSSKTAKEEGHHHHHH*

Coding Sequence Details

Insert Sequence Verified?:

Verification Method:

Sequence Verification

Mutations:

None

Discrepancy:

None

5' Linker Sequence:

None

3' Linker Sequence:

None

Recommended Growth Condition:

Distributed in bacterial strain:

DH5-alpha T1 phage resistant

Antibiotic Selection:

Host Type: bacterial Marker: kanamycin

Bacterial Selection Condition: 50ug/mL kanamycin

Growth Condition: Growth with the single antibiotic in LB at 37 degrees is recommended.

Comments: Conditions for Gateway-type vectors in recombined (with insert) form and other kanamycin resistant vectors.

Protein Expression Results:

ProteinPurified: Not_Tested

ProteinExpressed: Protein_Confirmed

SolubleProtein: Tested_Not_Soluble

Find experimental protocols in NYSGXRC-13030a

Recommended expression in:

Not Applicable

Vector Name:

pSGX3

Synonyms:

pSGX-3, pSGX3_BC

Sequencing Primer:

Forward: T7

Reverse: T7 terminator

Description:

Bacterial (E. coli) expression vector with T7 promoter, adds C-terminal 6xHis tag; kanamycin resistance; TOPO cloning.

Comments:

Modified from pET26b from Novagen

Size (bp):

5339

Parent Vector:

None

Properties:

TOPO Cloning, bacterial expression, in vitro transcription, with tag/fusion/marker

Author Name:

New York SGX Research Center for Structural Genomics

Publications:

None

Vector Map:

Vector Sequence:

Sequence:

TGGCGAATGGGACGCGCCCTGTAGCGGCGCATTAAGCGCGGCGGGTGTGGTGGTTACGCGCAGCGTGACCGCTACACTTGCCAGCGCCCTAGCGCCCGCTCCTTTCGCTTTCTTCCCTTCCTTTCTCGCCACGTTCGCCGGCTTTCCCCGTCAAGCTCTAAATCGGGGGCTCCCTTTAGGGTTCCGATTTAGTGCTTTACGGCACCTCGACCCCAAAAAACTTGATTAGGGTGATGGTTCACGTAGTGGGCCATCGCCCTGATAGACGGTTTTTCGCCCTTTGACGTTGGAGTCCACGTTCTTTAATAGTGGACTCTTGTTCCAAACTGGAACAACACTCAACCCTATCTCGGTCTATTCTTTTGATTTATAAGGGATTTTGCCGATTTCGGCCTATTGGTTAAAAAATGAGCTGATTTAACAAAAATTTAACGCGAATTTTAACAAAATATTAACGTTTACAATTTCAGGTGGCACTTTTCGGGGAAATGTGCGCGGAACCCCTATTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCATGAATTAATTCTTAGAAAAACTCATCGAGCATCAAATGAAACTGCAATTTATTCATATCAGGATTATCAATACCATATTTTTGAAAAAGCCGTTTCTGTAATGAAGGAGAAAACTCACCGAGGCAGTTCCATAGGATGGCAAGATCCTGGTATCGGTCTGCGATTCCGACTCGTCCAACATCAATACAACCTATTAATTTCCCCTCGTCAAAAATAAGGTTATCAAGTGAGAAATCACCATGAGTGACGACTGAATCCGGTGAGAATGGCAAAAGTTTATGCATTTCTTTCCAGACTTGTTCAACAGGCCAGCCATTACGCTCGTCATCAAAATCACTCGCATCAACCAAACCGTTATTCATTCGTGATTGCGCCTGAGCGAGACGAAATACGCGATCGCTGTTAAAAGGACAATTACAAACAGGAATCGAATGCAACCGGCGCAGGAACACTGCCAGCGCATCAACAATATTTTCACCTGAATCAGGATATTCTTCTAATACCTGGAATGCTGTTTTCCCGGGGATCGCAGTGGTGAGTAACCATGCATCATCAGGAGTACGGATAAAATGCTTGATGGTCGGAAGAGGCATAAATTCCGTCAGCCAGTTTAGTCTGACCATCTCATCTGTAACATCATTGGCAACGCTACCTTTGCCATGTTTCAGAAACAACTCTGGCGCATCGGGCTTCCCATACAATCGATAGATTGTCGCACCTGATTGCCCGACATTATCGCGAGCCCATTTATACCCATATAAATCAGCATCCATGTTGGAATTTAATCGCGGCCTAGAGCAAGACGTTTCCCGTTGAATATGGCTCATAACACCCCTTGTATTACTGTTTATGTAAGCAGACAGTTTTATTGTTCATGACCAAAATCCCTTAACGTGAGTTTTCGTTCCACTGAGCGTCAGACCCCGTAGAAAAGATCAAAGGATCTTCTTGAGATCCTTTTTTTCTGCGCGTAATCTGCTGCTTGCAAACAAAAAAACCACCGCTACCAGCGGTGGTTTGTTTGCCGGATCAAGAGCTACCAACTCTTTTTCCGAAGGTAACTGGCTTCAGCAGAGCGCAGATACCAAATACTGTCCTTCTAGTGTAGCCGTAGTTAGGCCACCACTTCAAGAACTCTGTAGCACCGCCTACATACCTCGCTCTGCTAATCCTGTTACCAGTGGCTGCTGCCAGTGGCGATAAGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACGGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACTGAGATACCTACAGCGTGAGCTATGAGAAAGCGCCACGCTTCCCGAAGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGCGCACGAGGGAGCTTCCAGGGGGAAACGCCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGACTTGAGCGTCGATTTTTGTGATGCTCGTCAGGGGGGCGGAGCCTATGGAAAAACGCCAGCAACGCGGCCTTTTTACGGTTCCTGGCCTTTTGCTGGCCTTTTGCTCACATGTTCTTTCCTGCGTTATCCCCTGATTCTGTGGATAACCGTATTACCGCCTTTGAGTGAGCTGATACCGCTCGCCGCAGCCGAACGACCGAGCGCAGCGAGTCAGTGAGCGAGGAAGCGGAAGAGCGCCTGATGCGGTATTTTCTCCTTACGCATCTGTGCGGTATTTCACACCGCATATATGGTGCACTCTCAGTACAATCTGCTCTGATGCCGCATAGTTAAGCCAGTATACACTCCGCTATCGCTACGTGACTGGGTCATGGCTGCGCCCCGACACCCGCCAACACCCGCTGACGCGCCCTGACGGGCTTGTCTGCTCCCGGCATCCGCTTACAGACAAGCTGTGACCGTCTCCGGGAGCTGCATGTGTCAGAGGTTTTCACCGTCATCACCGAAACGCGCGAGGCAGCTGCGGTAAAGCTCATCAGCGTGGTCGTGAAGCGATTCACAGATGTCTGCCTGTTCATCCGCGTCCAGCTCGTTGAGTTTCTCCAGAAGCGTTAATGTCTGGCTTCTGATAAAGCGGGCCATGTTAAGGGCGGTTTTTTCCTGTTTGGTCACTGATGCCTCCGTGTAAGGGGGATTTCTGTTCATGGGGGTAATGATACCGATGAAACGAGAGAGGATGCTCACGATACGGGTTACTGATGATGAACATGCCCGGTTACTGGAACGTTGTGAGGGTAAACAACTGGCGGTATGGATGCGGCGGGACCAGAGAAAAATCACTCAGGGTCAATGCCAGCGCTTCGTTAATACAGATGTAGGTGTTCCACAGGGTAGCCAGCAGCATCCTGCGATGCAGATCCGGAACATAATGGTGCAGGGCGCTGACTTCCGCGTTTCCAGACTTTACGAAACACGGAAACCGAAGACCATTCATGTTGTTGCTCAGGTCGCAGACGTTTTGCAGCAGCAGTCGCTTCACGTTCGCTCGCGTATCGGTGATTCATTCTGCTAACCAGTAAGGCAACCCCGCCAGCCTAGCCGGGTCCTCAACGACAGGAGCACGATCATGCGCACCCGTGGGGCCGCCATGCCGGCGATAATGGCCTGCTTCTCGCCGAAACGTTTGGTGGCGGGACCAGTGACGAAGGCTTGAGCGAGGGCGTGCAAGATTCCGAATACCGCAAGCGACAGGCCGATCATCGTCGCGCTCCAGCGAAAGCGGTCCTCGCCGAAAATGACCCAGAGCGCTGCCGGCACCTGTCCTACGAGTTGCATGATAAAGAAGACAGTCATAAGTGCGGCGACGATAGTCATGCCCCGCGCCCACCGGAAGGAGCTGACTGGGTTGAAGGCTCTCAAGGGCATCGGTCGAGATCCCGGTGCCTAATGAGTGAGCTAACTTACATTAATTGCGTTGCGCTCACTGCCCGCTTTCCAGTCGGGAAACCTGTCGTGCCAGCTGCATTAATGAATCGGCCAACGCGCGGGGAGAGGCGGTTTGCGTATTGGGCGCCAGGGTGGTTTTTCTTTTCACCAGTGAGACGGGCAACAGCTGATTGCCCTTCACCGCCTGGCCCTGAGAGAGTTGCAGCAAGCGGTCCACGCTGGTTTGCCCCAGCAGGCGAAAATCCTGTTTGATGGTGGTTAACGGCGGGATATAACATGAGCTGTCTTCGGTATCGTCGTATCCCACTACCGAGATATCCGCACCAACGCGCAGCCCGGACTCGGTAATGGCGCGCATTGCGCCCAGCGCCATCTGATCGTTGGCAACCAGCATCGCAGTGGGAACGATGCCCTCATTCAGCATTTGCATGGTTTGTTGAAAACCGGACATGGCACTCCAGTCGCCTTCCCGTTCCGCTATCGGCTGAATTTGATTGCGAGTGAGATATTTATGCCAGCCAGCCAGACGCAGACGCGCCGAGACAGAACTTAATGGGCCCGCTAACAGCGCGATTTGCTGGTGACCCAATGCGACCAGATGCTCCACGCCCAGTCGCGTACCGTCTTCATGGGAGAAAATAATACTGTTGATGGGTGTCTGGTCAGAGACATCAAGAAATAACGCCGGAACATTAGTGCAGGCAGCTTCCACAGCAATGGCATCCTGGTCATCCAGCGGATAGTTAATGATCAGCCCACTGACGCGTTGCGCGAGAAGATTGTGCACCGCCGCTTTACAGGCTTCGACGCCGCTTCGTTCTACCATCGACACCACCACGCTGGCACCCAGTTGATCGGCGCGAGATTTAATCGCCGCGACAATTTGCGACGGCGCGTGCAGGGCCAGACTGGAGGTGGCAACGCCAATCAGCAACGACTGTTTGCCCGCCAGTTGTTGTGCCACGCGGTTGGGAATGTAATTCAGCTCCGCCATCGCCGCTTCCACTTTTTCCCGCGTTTTCGCAGAAACGTGGCTGGCCTGGTTCACCACGCGGGAAACGGTCTGATAAGAGACACCGGCATACTCTGCGACATCGTATAACGTTACTGGTTTCACATTCACCACCCTGAATTGACTCTCTTCCGGGCGCTATCATGCCATACCGCGAAAGGTTTTGCGCCATTCGATGGTGTCCGGGATCTCGACGCTCTCCCTTATGCGACTCCTGCATTAGGAAGCAGCCCAGTAGTAGGTTGAGGCCGTTGAGCACCGCCGCCGCAAGGAATGGTGCATGCAAGGAGATGGCGCCCAACAGTCCCCCGGCCACGGGGCCTGCCACCATACCCACGCCGAAACAAGCGCTCATGAGCCCGAAGTGGCGAGCCCGATCTTCCCCATCGGTGATGTCGGCGATATAGGCGCCAGCAACCGCACCTGTGGCGCCGGTGATGCCGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAATTCCCCTCTAGAAATAATTTTGTTTAACTTTAAGAAGGAGATATACATATGTCCCTTAAGGGCATCATCACCATCACCACTGATCCCACCACCACCACCACCACTGAGATCCGAATTCGAGCTCCGTCGACAAGCTTGCGGCCGCACTCGAGCACCACCACCACCACCACTGAGATCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATAACTAGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGGAGGAACTATATCCGGAT

Vector Features:

Type

Name

Description

Start

End

ATG start

start

initiation start (Met, Ser, Leu)

5072

5079

TOPO recognition site

TOPO

TOPO cloning site

5076

5085

bacterial origin

ori

pBR322-type bacterial origin of replication

1421

2103

gene fragment

ROP

2527

2703

promoter

T7 promoter

4983

5003

repressor protein gene

LacI

LacI CDS

3515

4531

selectable marker

KanR

kanamycin resistance gene

563

1375

tag

His

6xHis tag

5086

5103

trxn regulatory element

lac operator

5003

5025

trxn termination sequence

T7 term

T7 terminator

5231

5307

Gene

Gene Symbol :

SKIL

Symbol Nomenclature :

SKIL

SYNONYM :

SNO; SnoA; SnoI; SnoN

Designation :

ski-like protein|ski-related oncogene snoN

Full Nomenclature :

SKI-like oncogene

GENEID :

6498

GI :

223029418

GenBank Accession :

NM_005414

HGNC :

10897

MIM :

165340

Vega :

OTTHUMG00000158831

Target GenBank:

None

Reference Sequence Alignment

  

HsCD00531586        ---GAAAACCTGCAAACTAATTTCAGCCTGGTCCAGGGTTCGACAAAAAAACTGAATGGG
NM_005414.4         ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
XM_005247721.1      ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
NM_001145098.2      ------------------------------------------------------------
NM_001248008.1      ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
NM_001145097.2      ATGGAAAACCTCCAGACAAATTTCTCCTTGGTTCAGGGCTCAACTAAAAAACTGAATGGG
                                                                                

HsCD00531586        ATGGGTGATGACGGCAGCCCCCCTGCCAAGAAAATGATAACGGACATTCATGTTAATGGT
NM_005414.4         ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
XM_005247721.1      ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
NM_001145098.2      ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
NM_001248008.1      ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
NM_001145097.2      ATGGGAGATGATGGCAGCCCCCCAGCGAAAAAAATGATAACGGACATTCATGCAAATGGA
                    *****:***** ***********:** **.********************** :*****:

HsCD00531586        AAGACAATCAATAAGGTGCCAACAGTTAAGAAAGAGCACTTGGATGACTATGGAGAAGCA
NM_005414.4         AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
XM_005247721.1      AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
NM_001145098.2      AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
NM_001248008.1      AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
NM_001145097.2      AAAACGATAAACAAGGTGCCAACAGTTAAGAAGGAACACTTGGATGACTATGGAGAAGCA
                    **.**.**.** ********************.**.************************

HsCD00531586        CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
NM_005414.4         CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
XM_005247721.1      CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
NM_001145098.2      CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
NM_001248008.1      CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
NM_001145097.2      CCAGTGGAAACTGATGGAGAGCATGTTAAGCGAACCTGTACTTCTGTTCCTGAAACTTTG
                    ************************************************************

HsCD00531586        CATTTAAATCCCAGTTTGAAACACACATTGGCCCAATTCCATCTGTCGTCTCAATCCTCG
NM_005414.4         CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
XM_005247721.1      CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
NM_001145098.2      CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
NM_001248008.1      CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
NM_001145097.2      CATTTAAATCCCAGTTTGAAACACACATTGGCACAATTCCATTTAAGTAGTCAGAGCTCG
                    ********************************.********* *.:  : ***.: ****

HsCD00531586        CTGGGTGGACCAGCAGCTTTCAGTGCCCGGCATTCCCAAGAAAGCATGTCGCCTACAGTC
NM_005414.4         CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
XM_005247721.1      CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
NM_001145098.2      CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
NM_001248008.1      CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
NM_001145097.2      CTGGGTGGACCAGCAGCATTTTCTGCTCGGCATTCCCAAGAAAGCATGTCGCCTACTGTA
                    *****************:** : *** *****************************:**.

HsCD00531586        TTCTTGCCACTGCCCAGTCCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTAGTGACTCC
NM_005414.4         TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
XM_005247721.1      TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
NM_001145098.2      TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
NM_001248008.1      TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
NM_001145097.2      TTTCTGCCTCTTCCATCACCTCAGGTTCTTCCTGGCCCATTGCTCATCCCTTCAGATAGC
                    **  ****:** **.: :*********************************: :** : *

HsCD00531586        TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCATGTTTCCAGGTGGGC
NM_005414.4         TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
XM_005247721.1      TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
NM_001145098.2      TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
NM_001248008.1      TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
NM_001145097.2      TCCACAGAACTCACTCAGACTGTGTTGGAAGGGGAATCTATTTCTTGTTTTCAAGTTGGA
                    ********************************************:***** **.** **.

HsCD00531586        GGAGAAAAGAGACTCTGCCTGCCACAGGTATTGAACTCGGTTCTGCGTGAGTTTACTCTG
NM_005414.4         GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
XM_005247721.1      GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
NM_001145098.2      GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
NM_001248008.1      GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
NM_001145097.2      GGAGAAAAGAGACTCTGTTTGCCCCAAGTCTTAAATTCTGTTCTCCGAGAATTTACACTC
                    *****************  ****.**.**.**.** ** ***** **:**.*****:** 

HsCD00531586        CAACAGATCAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCTGAT
NM_005414.4         CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
XM_005247721.1      CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
NM_001145098.2      CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
NM_001248008.1      CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
NM_001145097.2      CAGCAAATAAATACAGTGTGTGATGAACTGTACATATATTGTTCAAGGTGTACTTCAGAC
                    **.**.**.***********************************************:** 

HsCD00531586        CAGCTTCATATCTTAAAGGTACTGGGCATTTTGCCTTTCAACGCTCCATCCTGTGGGCTG
NM_005414.4         CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
XM_005247721.1      CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
NM_001145098.2      CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
NM_001248008.1      CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
NM_001145097.2      CAGCTTCATATCTTAAAGGTACTGGGCATACTTCCATTCAATGCCCCATCCTGTGGGCTG
                    *****************************: * **:***** ** ***************

HsCD00531586        ATTACATTAACTGATGCACAACGTCTGTGTAACGCTTTGCTGCGGCCACGAACTTTTCCT
NM_005414.4         ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
XM_005247721.1      ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
NM_001145098.2      ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
NM_001248008.1      ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
NM_001145097.2      ATTACATTAACTGATGCACAAAGATTATGTAATGCTTTATTGCGGCCACGAACTTTTCCT
                    *********************.*: *.***** *****. ********************

HsCD00531586        CAAAATGGTAGCGTTTTGCCTGCAAAGTCCTCATTGGCCCAGTTAAAGGAAACTGGCTCG
NM_005414.4         CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
XM_005247721.1      CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
NM_001145098.2      CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
NM_001248008.1      CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
NM_001145097.2      CAAAATGGTAGCGTACTTCCTGCTAAAAGCTCATTGGCCCAGTTAAAGGAAACTGGCAGT
                    **************: * *****:**.: ****************************:  

HsCD00531586        GCATTTGAAGTCGAGCATGAATGCCTAGGCAAGTGCCAGGGCCTGTTTGCTCCCCAGTTC
NM_005414.4         GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
XM_005247721.1      GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
NM_001145098.2      GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
NM_001248008.1      GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
NM_001145097.2      GCCTTTGAAGTGGAGCATGAATGCCTAGGCAAATGTCAGGGTTTATTTGCACCCCAGTTT
                    **.******** ********************.** *****  *.*****:******** 

HsCD00531586        TATGTACAGCCAGATGCTCCGTGCATCCAGTGTTTGGAGTGTTGTGGAATGTTTGCGCCC
NM_005414.4         TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
XM_005247721.1      TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
NM_001145098.2      TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
NM_001248008.1      TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
NM_001145097.2      TATGTTCAGCCTGATGCTCCGTGTATTCAATGTCTGGAGTGTTGTGGAATGTTTGCACCC
                    *****:*****:*********** ** **.*** **********************.***

HsCD00531586        CAAACTTTTGTGATGCATAGCCACAGATCACCTGACAAACGCACTTGCCACTGGGGCTTT
NM_005414.4         CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
XM_005247721.1      CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
NM_001145098.2      CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
NM_001248008.1      CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
NM_001145097.2      CAGACGTTTGTGATGCATTCTCACAGATCACCTGACAAAAGAACTTGCCACTGGGGCTTT
                    **.** ************:  ******************.*.******************

HsCD00531586        GAATCAGCTAAATGGCATTGCTATCTGCATGTTAACCAAAAATACTTGGGCACCCCCGAG
NM_005414.4         GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
XM_005247721.1      GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
NM_001145098.2      GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
NM_001248008.1      GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
NM_001145097.2      GAATCAGCTAAATGGCATTGCTATCTTCATGTGAACCAAAAATACTTAGGAACACCTGAA
                    ************************** ***** **************.**.**.** **.

HsCD00531586        GAGAAGAAATTGAAAATTATTTTAGAGGAAATGAAGGAAAAGTTTTCTATGAGAAGTGGA
NM_005414.4         GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
XM_005247721.1      GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
NM_001145098.2      GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
NM_001248008.1      GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
NM_001145097.2      GAAAAGAAACTGAAGATAATTTTAGAAGAAATGAAGGAGAAGTTTAGCATGAGAAGTGGA
                    **.****** ****.**:********.***********.******:  ************

HsCD00531586        AAGAGAAATCAATCCAAGACAGATGCGCCGTCTGGCATGGAATTACAGTCATGGTATCCG
NM_005414.4         AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
XM_005247721.1      AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
NM_001145098.2      AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
NM_001248008.1      AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
NM_001145097.2      AAGAGAAATCAATCCAAGACAGATGCACCATCAGGAATGGAATTACAGTCATGGTATCCT
                    **************************.**.**:**.*********************** 

HsCD00531586        GTTATTAAGCAGGAAGGTGACCATGTTTCTCAAACTCATTCGTTTTTGCATCCCTCGTAT
NM_005414.4         GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
XM_005247721.1      GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
NM_001145098.2      GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
NM_001248008.1      GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
NM_001145097.2      GTTATAAAGCAGGAAGGTGACCATGTTTCTCAGACACATTCATTTTTACACCCCAGCTAC
                    *****:**************************.**:*****.*****.** ***:  ** 

HsCD00531586        TACTTATACATGTGCGACAAAGTGGTGGCTCCCAACGTGTCACTTACCTCTGCTGTTTCC
NM_005414.4         TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
XM_005247721.1      TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
NM_001145098.2      TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
NM_001248008.1      TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
NM_001145097.2      TACTTATACATGTGTGATAAAGTGGTTGCCCCAAATGTGTCACTTACTTCTGCTGTATCC
                    ************** ** ******** ** **.** *********** ********:***

HsCD00531586        CAGTCTAAAGAGCTGACAAAAACCGAGGCTAGTAAGTCCATATCCCGTCAGTCTGAAAAA
NM_005414.4         CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
XM_005247721.1      CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
NM_001145098.2      CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
NM_001248008.1      CAGTCTAAAGAGCTCACAAAGACAGAGGCAAGTAAGTCCATATCAAGACAGTCAGAGAAG
NM_001145097.2      CAGTCTAAAGAGCTCACAAAGACAGAG---------------------------------
                    ************** *****.**.***                                 

HsCD00531586        GCTCATTCTAGTGGCAAGCTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTGGAAGAG
NM_005414.4         GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
XM_005247721.1      GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
NM_001145098.2      GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
NM_001248008.1      GCTCACAGTAGTGGTAAACTTCAAAAAACAGTGTCTTATCCAGATGTCTCACTTGAGGAA
NM_001145097.2      ------------------------------------------------------------
                                                                                

HsCD00531586        CAAGAAAAAATGGACCTGAAAACAAGTCGCGAATTGTGCAGTCGTTTGGATGCATCCATC
NM_005414.4         CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
XM_005247721.1      CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
NM_001145098.2      CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
NM_001248008.1      CAGGAGAAAATGGATTTAAAAACAAGTAGAGAATTATGTAGCCGTTTAGATGCATCAATC
NM_001145097.2      ---------------------------------------------GCAAATGCATCAATC
                                                                   ..*******.***

HsCD00531586        TCAAACAATTCTACATCCAAGCGTAAATCTGAGTCTGCCACTTGCAACCTGGTACGCGAT
NM_005414.4         TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
XM_005247721.1      TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
NM_001145098.2      TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
NM_001248008.1      TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
NM_001145097.2      TCAAATAATTCTACAAGTAAAAGGAAATCTGAGTCTGCCACTTGCAACTTAGTCAGAGAC
                    ***** *********:  **..* ************************ *.**..*.** 

HsCD00531586        ATTAACAAAGTGGGAATTGGCTTGGTCGCCGCAGCTAGCTCTCCGCTTCTTGTGAAAGAT
NM_005414.4         ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
XM_005247721.1      ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
NM_001145098.2      ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
NM_001248008.1      ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
NM_001145097.2      ATAAACAAAGTGGGAATTGGCCTTGTTGCTGCCGCTTCATCTCCGCTTCTTGTGAAAGAT
                    **:****************** * ** ** **.***: .*********************

HsCD00531586        GTCATCTGTGAGGATGATAAGGGCAAAATCATGGAAGAGGTCATGAGAACTTATCTGAAA
NM_005414.4         GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
XM_005247721.1      GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
NM_001145098.2      GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
NM_001248008.1      GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
NM_001145097.2      GTCATTTGTGAGGATGATAAGGGAAAAATCATGGAAGAAGTAATGAGAACTTATTTAAAA
                    ***** *****************.**************.**.************ *.***

HsCD00531586        CAACAAGAGAAACTGAACTTGATTCTGCAAAAGAAACAGCAATTGCAAATGGAGGTCAAA
NM_005414.4         CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
XM_005247721.1      CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
NM_001145098.2      CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
NM_001248008.1      CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
NM_001145097.2      CAACAGGAAAAACTAAACTTGATTTTGCAAAAGAAGCAACAACTTCAGATGGAAGTAAAA
                    *****.**.*****.********* **********.**.*** * **.*****.**.***

HsCD00531586        ATGTTGAGTAGTTCAAAATCGATGAAAGAACTGACAGAAGAGCAACAGAATTTGCAAAAG
NM_005414.4         ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
XM_005247721.1      ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
NM_001145098.2      ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
NM_001248008.1      ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
NM_001145097.2      ATGTTGAGTAGTTCAAAATCTATGAAGGAACTCACTGAAGAACAGCAGAATTTACAGAAA
                    ******************** *****.***** **:*****.**.********.**.**.

HsCD00531586        GAGCTGGAATCTTTGCAGAATGAACACGCACAGCGTATGGAGGAATTTTACGTTGAGCAG
NM_005414.4         GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
XM_005247721.1      GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
NM_001145098.2      GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
NM_001248008.1      GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
NM_001145097.2      GAGCTTGAATCTTTGCAGAATGAACATGCTCAAAGAATGGAAGAATTTTATGTTGAACAG
                    ***** ******************** **:**..*:*****.******** *****.***

HsCD00531586        AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAGAAATGCACATGTGACTCAAAT
NM_005414.4         AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
XM_005247721.1      AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
NM_001145098.2      AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
NM_001248008.1      AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
NM_001145097.2      AAAGACTTAGAGAAAAAATTGGAGCAGATAATGAAGCAAAAATGTACCTGTGACTCAAAT
                    **************************************.***** **.************

HsCD00531586        TTAGAAAAGGATAAAGAAGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
NM_005414.4         TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
XM_005247721.1      TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
NM_001145098.2      TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
NM_001248008.1      TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
NM_001145097.2      TTAGAAAAAGACAAAGAGGCTGAATATGCAGGACAGTTGGCAGAACTGAGGCAGAGATTG
                    ********.** *****.******************************************

HsCD00531586        GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGACGAGTTGAGACAGGAACGGGAAGCA
NM_005414.4         GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
XM_005247721.1      GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
NM_001145098.2      GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
NM_001248008.1      GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
NM_001145097.2      GACCATGCTGAGGCCGATAGGCAAGAACTCCAAGATGAACTCAGACAGGAACGGGAAGCA
                    *********************************** **. * ******************

HsCD00531586        AGACAGAAGTTAGAGATGATGATAAAAGAGCTGAAATTGCAGATTCTGAAATCATCAAAG
NM_005414.4         AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
XM_005247721.1      AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
NM_001145098.2      AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
NM_001248008.1      AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
NM_001145097.2      AGACAGAAGTTAGAGATGATGATAAAAGAGCTAAAGCTGCAAATTCTGAAATCATCAAAG
                    ********************************.**. ****.******************

HsCD00531586        ACTGCCAAAGAAGAAGGGCATCATCACCATCACCACTGA
NM_005414.4         ACTGCTAAAGAATAG------------------------
XM_005247721.1      ACTGCTAAAGAATAG------------------------
NM_001145098.2      ACTGCTAAAGAATAG------------------------
NM_001248008.1      ACTGCTAAAGAATAG------------------------
NM_001145097.2      ACTGCTAAAGAATAG------------------------
                    ***** ****** *.

Pathways

NCI :

Regulation of nuclear SMAD2/3 signaling

NCI :

TGF-beta receptor signaling

Panther :

Gonadotropin-releasing hormone receptor pathway

Panther :

TGF-beta signaling pathway

Reactome :

Disease

Reactome :

Downregulation of SMAD2/3:SMAD4 transcriptional activity

Reactome :

Gene Expression

Reactome :

Generic Transcription Pathway

Reactome :

Loss of Function of SMAD2/3 in Cancer

Reactome :

Loss of Function of SMAD4 in Cancer

Reactome :

Loss of Function of TGFBR1 in Cancer

Reactome :

Loss of Function of TGFBR2 in Cancer

Reactome :

Signal Transduction

Reactome :

Signaling by TGF-beta Receptor Complex

Reactome :

Signaling by TGF-beta Receptor Complex in Cancer

Reactome :

SMAD2/3 MH2 Domain Mutants in Cancer

Reactome :

SMAD2/3 Phosphorylation Motif Mutants in Cancer

Reactome :

SMAD4 MH2 Domain Mutants in Cancer

Reactome :

TGFBR1 KD Mutants in Cancer

Reactome :

TGFBR1 LBD Mutants in Cancer

Reactome :

TGFBR2 Kinase Domain Mutants in Cancer

Reactome :

TGFBR2 MSI Frameshift Mutants in Cancer

Reactome :

Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer

WikiPathway :

TGF beta Signaling Pathway

WikiPathway :

TGF Beta Signaling Pathway

Protein

SMART domain :

c-SKI_SMAD_bind : c-SKI Smad4 binding domain

Structural Annotation Wiki :

NYSGXRC-13030a

HPRD :

01319

Clone

Cloning Information :

480499

HIP Master Clone ID :

398392

Original Clone ID :

13030a3BCt19p1

Experimental

TargetTrack - Experimental data :

NYSGXRC-13030a

Organism

Species Specific ID:

6498

Genome

Chromosome :

Map Location :

3q26

Ensembl :

ENSG00000136603

Reagents

Labome :

SnoN-antibody

SKIL (H. sapiens )In pSGX3 (His-tagged bacterial expression vector)

Coding Sequence Details

Recommended Growth Condition:

Vector Features:

Gene

Reference Sequence Alignment

Pathways

Protein

Clone

Experimental

Organism

Genome

Reagents

SKIL (H. sapiens )
In pSGX3 (His-tagged bacterial expression vector)