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IQSEC1 (Homo sapiens) in pLX304 (Gateway V5-tagged lentiviral expression vector)

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Explanation of Terms


Gene: Gene Symbol:  IQSEC1
Gene Name:  IQ motif and Sec7 domain 1
Sequence             
Original Clone ID: ccsbBroad304_14033
Keyword: None
Species: Homo sapiens
Type: cDNA
Vector Name: pLX304               Format:  FUSION
Source: The ORFeome Collaboration
Description: None
Comments: None
Mutation/
Discrepancy :
No / Yes
Publications: None
Authors: The ORFeome Collaboration
Dana-Farber Cancer Institute
Broad Institute of Harvard and Massachusetts Institute of Technology (MIT)
David E Hill
David E Root
Harvard Medical School
HsCD00445243

Price:  Login for Pricing
AVAILABLE
No restriction
Special MTA: None

 

Insert sequence: 2443nts         Open reading frame : 1 to 2443
Reference Sequence Alignment

ATGCTAGAACGAAAGTATGGGGGGCGCCTGGTAACCCGCCATGCGGCCCGCACCATCCAG
ACGGCGTTTCGCCAGTACCAGATGAACAAGAACTTCGAGCGCTTGCGCAGCTCCATGTCA
GAGAACCGCATGTCACGCCGGATTGTGCTGTCCAACATGAGGATGCAGTTCTCCTTTGAG
GGGCCTGAGAAAGTGCACAGCTCCTACTTCGAGGGGAAGCAGGTCTCAGTGACTAACGAC
GGCTCCCAGCTGGGAGCCCTGGTGTCCCCTGAGTGTGGTGACCTCAGCGAGCCCACCACC
CTCAAGTCTCCGGCCCCCTCCAGTGACTTTGCGGACGCCATCACCGAGCTGGAGGACGCC
TTCTCTAGGCAAGTGAAATCACTGGCCGAGTCCATCGACGATGCCCTCAACTGCCGCAGC
CTGCACACTGAGGAGGCACCGGCCCTGGATGCGGCGCGGGCCCGGGACACCGAACCCCAG
ACAGCCCTGCACGGCATGGACCACCGCAAACTGGACGAGATGACGGCCTCGTACAGTGAT
GTCACCCTGTACATCGATGAGGAGGAGCTGTCGCCCCCTCTGCCCCTCTCGCAGGCAGGG
GACCGGCCGTCCAGCACCGAGTCGGACCTGCGGCTACGGGCTGGGGGCGCAGCCCCAGAC
TACTGGGCCCTGGCCCACAAAGAGGACAAGGCTGACACGGACACGAGCTGCCGGAGCACG
CCGTCGCTGGAGCGGCAGGNGCAGCGGCTGCGGGTGGAGCATCTGCCGCTGCTCACCATC
GAGCCACCCAGCGACAGCTCTGTGGACCTTAGTGACCGCTCGGAGCGGGGGTCACTCAAG
AGGCAGAGTGCTTACGAGCGCAGCCTTGGCGGGCAGCAGGGCAGTCCCAAGCATGGTCCC
CACAGCGGCGCCCCCAAGAGCCTCCCCCGGGAGGAGCCTGAGTTGCGGCCCCGGCCCCCC
AGGCCCCTGGACAGCCACTTGGCCATCAATGGCTCAGCCAACCGGCAGAGCAAGTCTGAG
TCGGACTACTCAGACGGTGACAATGACAGCATCAACAGCACGTCCAACTCCAACGATACC
ATCAACTGCAGCTCCGAGTCATCGTCCCGTGACAGCCTGCGGGAGCAGACGCTCAGCAAG
CAGACCTACCACAAGGAGGCCCGCAACAGCTGGGACTCGCCTGCCTTTAGCAACGATGTC
ATCCGCAAGAGGCACTACCGCATCGGCCTGAACCTCTTCAACAAGAAGCCTGAGAAGGGA
GTCCAGTACCTCATCGAGCGTGGCTTTGTGCCCGACACGCCCGTCGGGGTGGCCCACTTC
CTGCTGCAGCGCAAGGGCCTCAGCCGGCAGATGATCGGCGAGTTCCTGGGCAACCGGCAG
AAGCAGTTCAACCGTGACGTGCTCGACTGCGTCGTGGACGAGATGGACTTCTCTACCATG
GAGCTGGATGAGGCCCTCAGGAAATTCCAGGCGCACATCCGTGTCCAAGGGGAGGCTCAG
AAAGTGGAGCGGCTCATAGAGGCGTTCAGCCAGCGCTACTGCATCTGCAACCCTGGGGTG
GTGCGGCAATTCCGGAACCCAGACACCATTTTCATCCTGGCCTTCGCCATCATCCTGCTG
AACACCGACATGTACAGCCCCAATGTCAAGCCCGAGCGGAAAATGAAGCTAGAGGACTTC
ATCAAGAACCTCCGAGGTGTGGACGATGGTGAGGACATTCCCCGTGAGATGCTGATGGGG
ATCTATGAACGGATCCGTAAGCGAGAGCTAAAGACCAATGAGGACCATGTGTCCCAGGTG
CAGAAGGTGGAGAAGCTCATTGTGGGGAAAAAGCCGATCGGATCCCTGCATCCCGGGCTC
GGCTGTGTGCTCTCTCTGCCCCACCGTCGGTTGGTCTGCTACTGCCGGCTCTTTGAGGTT
CCAGACCCAAACAAGCCCCAGAAACTCGGACTACACCAGCGAGAAATCTTCCTGTTCAAC
GACCTCCTGGTGGTCACCAAGATCTTCCAGAAGAAGAAGAACTCGGTGACGTACAGCTTC
CGACAGTCCTTCTCCTTGTACGGCATGCAGGTCCTGCTCTTCGAGAACCAGTACTACCCC
AATGGCATCCGGCTCACCTCGTCTGTCCCCGGAGCAGATATCAAAGTGTTAATAAACTTC
AACGCCCCCAACCCTCAAGACCGGAAGAAATTCACCGATGACCTGCGGGAGTCCATTGCG
GAAGTCCAAGAGATGGAGAAGCACAGGATAGAGTCGGAGCTCGAGAAGCAGAAAGGCGTC
GTGCGGCCCAGCATGTCCCAGTGCTCTAGCCTCAAAAAGGAGTCGGGCAACGGAACACTG
AGCCGGGCCTGCCTGGACGACAGCTATGCCAGCGGTGAGGGCCTCAAGCGCAGCGCCCTC
AGCAGCTCCCTGCGGGACCTCTCGGAAGCCGGGGTCCATCAT


Coding Sequence Details
Insert Sequence Verified?: N Verification Method: Verified by the ORFeome collaboration
Mutations:
None
Discrepancy:
1 error; 1 non-synonomous errors;
 Clone mixture?
                                

5' Linker Sequence: None
3' Linker Sequence: None

 

 Recommended Growth Condition:

Distributed in bacterial strain : DH5-alpha T1 phage resistant
Antibiotic Selection: Host Type:  bacterial    Marker:  ampicillin
Host Type:  mammalian    Marker:  blasticidin
Bacterial Selection Condition:  100 ug/mL ampicillin
Growth Condition:  Growth with the single antibiotic in LB at 37 degrees is recommended.
Comments:  Commonly used conditions for ampicillin resistant plasmid clones.
Protein Expression Results: None
Recommended expression in: Not Applicable
       DyNA Vector Map

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Vector Name: pLX304

pLX304 in advanced viewed

Synonyms: None
Sequencing Primer: Forward:  CMV forward
Reverse:  Unknown
Description: Gateway compatible lentiviral vector with a C-terminal V5 tag and CMV promoter for mammalian cell expression; blasticidin resistance in mammalian cells; ampicillin resistance in bacteria; Gateway cloning.
Comments: None
Size (bp): 9377
Parent Vector: None
Empty Vector: None
Properties: Gateway, acceptor (destination), lentiviral infection, recombinational cloning, with tag/fusion/marker
Author Name: David Root
Publications: PMID: 21706014
Title: A public genome-scale lentiviral expression library of human ORFs

Vector Map:         Vector Sequence:
Sequence:

 



Vector Features:

Type Name Description Start Position End Position
polypurine tract cPPT human immunodeficiency virus type 1 central polypurine tract 3027 3042
promoter T7 T7 promoter 3690 3672
promoter CMV CMV promoter 14 566
recombination site attR1 595 719
recombination site attR2 2282 2297
selectable marker CAT CAT/CamR Chloramphenical resistance 828 1487
selectable marker ccdB Control of cell death B gene 1829 2134
selectable marker AmpR Ampicillin resistance gene 4444 5304
selectable marker BlastR Blasticidin resistance gene 8753 9148
tag V5 C-terminal V5 tag 2301 2342
trxn regulatory element WPRE woodchuck hepatitis post-transcriptional regulatory element 2386 2961

 

  • Gene
  • Pathways
  • Protein
  • Clone
  • Organism
  • Genome
  • Reagents

Gene

 

Gene Symbol : IQSEC1
Symbol Nomenclature : IQSEC1
SYNONYM : ARF-GEP100; ARFGEP100; BRAG2; GEP100
Designation : ADP-ribosylation factors guanine nucleotide-exchange protein 100|ADP-ribosylation factors guanine nucleotide-exchange protein 2|IQ motif and SEC7 domain-containing protein 1|brefeldin A-resistant ARF-GEF2|brefeldin-resistant Arf-GEF 2 protein
Full Nomenclature : IQ motif and Sec7 domain 1
GENEID : 9922
HGNC : 29112
MIM : 610166
Vega : OTTHUMG00000155398
Target GenBank: None

 

Reference Sequence Alignment

  

HsCD00445243        ------------------------------------------------------------
NM_014869.5         ATGTGGTGCCTGCACTGCAACTCGGAGAGGACCCAGTCCCTTCTGGAGCTAGAGCTTGAC
NM_001134382.2      ------------------------------------------ATGGCTTGCAGAAGACGC
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         AGCGGCGTCGAGGGCGAGGCCCCCAGCAGTGAGACTGGCACATCCCTGGACAGCCCCTCA
NM_001134382.2      TATTTCGTCGAGGGCGAGGCCCCCAGCAGTGAGACTGGCACATCCCTGGACAGCCCCTCA
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         GCCTACCCCCAGGGCCCCTTGGTGCCCGGTTCCAGCCTGAGCCCGGATCACTACGAGCAC
NM_001134382.2      GCCTACCCCCAGGGCCCCTTGGTGCCCGGTTCCAGCCTGAGCCCGGATCACTACGAGCAC
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         ACGTCAGTGGGAGCCTATGGGCTGTACTCGGGGCCGCCGGGGCAACAGCAGCGCACGCGG
NM_001134382.2      ACGTCAGTGGGAGCCTATGGGCTGTACTCGGGGCCGCCGGGGCAACAGCAGCGCACGCGG
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         AGGCCCAAGCTGCAGCACTCGACCTCCATCCTGCGCAAGCAGGCTGAGGAGGAGGCCATC
NM_001134382.2      AGGCCCAAGCTGCAGCACTCGACCTCCATCCTGCGCAAGCAGGCTGAGGAGGAGGCCATC
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         AAGCGCTCACGCTCACTCTCCGAGAGCTATGAGCTCTCCTCGGACCTGCAGGACAAGCAG
NM_001134382.2      AAGCGCTCACGCTCACTCTCCGAGAGCTATGAGCTCTCCTCGGACCTGCAGGACAAGCAG
                                                                                

HsCD00445243        ------ATGCTAGAACGAAAGTATGGGGGGCGCCTGGTAACCCGCCATGCGGCCCGCACC
NM_014869.5         GTGGAGATGCTAGAACGAAAGTATGGGGGGCGCCTGGTAACCCGCCATGCGGCCCGCACC
NM_001134382.2      GTGGAGATGCTAGAACGAAAGTATGGGGGGCGCCTGGTAACCCGCCATGCGGCCCGCACC
                          ******************************************************

HsCD00445243        ATCCAGACGGCGTTTCGCCAGTACCAGATGAACAAGAACTTCGAGCGCTTGCGCAGCTCC
NM_014869.5         ATCCAGACGGCGTTTCGCCAGTACCAGATGAACAAGAACTTCGAGCGCTTGCGCAGCTCC
NM_001134382.2      ATCCAGACGGCGTTTCGCCAGTACCAGATGAACAAGAACTTCGAGCGCTTGCGCAGCTCC
                    ************************************************************

HsCD00445243        ATGTCAGAGAACCGCATGTCACGCCGGATTGTGCTGTCCAACATGAGGATGCAGTTCTCC
NM_014869.5         ATGTCAGAGAACCGCATGTCACGCCGGATTGTGCTGTCCAACATGAGGATGCAGTTCTCC
NM_001134382.2      ATGTCAGAGAACCGCATGTCACGCCGGATTGTGCTGTCCAACATGAGGATGCAGTTCTCC
                    ************************************************************

HsCD00445243        TTTGAGGGGCCTGAGAAAGTGCACAGCTCCTACTTCGAGGGGAAGCAGGTCTCAGTGACT
NM_014869.5         TTTGAGGGGCCTGAGAAAGTGCACAGCTCCTACTTCGAGGGGAAGCAGGTCTCAGTGACT
NM_001134382.2      TTTGAGGGGCCTGAGAAAGTGCACAGCTCCTACTTCGAGGGGAAGCAGGTCTCAGTGACT
                    ************************************************************

HsCD00445243        AACGACGGCTCCCAGCTGGGAGCCCTGGTGTCCCCTGAGTGTGGTGACCTCAGCGAGCCC
NM_014869.5         AACGACGGCTCCCAGCTGGGAGCCCTGGTGTCCCCTGAGTGTGGTGACCTCAGCGAGCCC
NM_001134382.2      AACGACGGCTCCCAGCTGGGAGCCCTGGTGTCCCCTGAGTGTGGTGACCTCAGCGAGCCC
                    ************************************************************

HsCD00445243        ACCACCCTCAAGTCTCCGGCCCCCTCCAGTGACTTTGCGGACGCCATCACCGAGCTGGAG
NM_014869.5         ACCACCCTCAAGTCTCCGGCCCCCTCCAGTGACTTTGCGGACGCCATCACCGAGCTGGAG
NM_001134382.2      ACCACCCTCAAGTCTCCGGCCCCCTCCAGTGACTTTGCGGACGCCATCACCGAGCTGGAG
                    ************************************************************

HsCD00445243        GACGCCTTCTCTAGGCAAGTGAAATCACTGGCCGAGTCCATCGACGATGCCCTCAACTGC
NM_014869.5         GACGCCTTCTCTAGGCAAGTGAAATCACTGGCCGAGTCCATCGACGATGCCCTCAACTGC
NM_001134382.2      GACGCCTTCTCTAGGCAAGTGAAATCACTGGCCGAGTCCATCGACGATGCCCTCAACTGC
                    ************************************************************

HsCD00445243        CGCAGCCTGCACACTGAGGAGGCACCGGCCCTGGATGCGGCGCGGGCCCGGGACACCGAA
NM_014869.5         CGCAGCCTGCACACTGAGGAGGCACCGGCCCTGGATGCGGCGCGGGCCCGGGACACCGAA
NM_001134382.2      CGCAGCCTGCACACTGAGGAGGCACCGGCCCTGGATGCGGCGCGGGCCCGGGACACCGAA
                    ************************************************************

HsCD00445243        CCCCAGACAGCCCTGCACGGCATGGACCACCGCAAACTGGACGAGATGACGGCCTCGTAC
NM_014869.5         CCCCAGACAGCCCTGCACGGCATGGACCACCGCAAACTGGACGAGATGACGGCCTCGTAC
NM_001134382.2      CCCCAGACAGCCCTGCACGGCATGGACCACCGCAAACTGGACGAGATGACGGCCTCGTAC
                    ************************************************************

HsCD00445243        AGTGATGTCACCCTGTACATCGATGAGGAGGAGCTGTCGCCCCCTCTGCCCCTCTCGCAG
NM_014869.5         AGTGATGTCACCCTGTACATCGATGAGGAGGAGCTGTCGCCCCCTCTGCCCCTCTCGCAG
NM_001134382.2      AGTGATGTCACCCTGTACATCGATGAGGAGGAGCTGTCGCCCCCTCTGCCCCTCTCGCAG
                    ************************************************************

HsCD00445243        GCAGGGGACCGGCCGTCCAGCACCGAGTCGGACCTGCGGCTACGGGCTGGGGGCGCAGCC
NM_014869.5         GCAGGGGACCGGCCGTCCAGCACCGAGTCGGACCTGCGGCTACGGGCTGGGGGCGCAGCC
NM_001134382.2      GCAGGGGACCGGCCGTCCAGCACCGAGTCGGACCTGCGGCTACGGGCTGGGGGCGCAGCC
                    ************************************************************

HsCD00445243        CCAGACTACTGGGCCCTGGCCCACAAAGAGGACAAGGCTGACACGGACACGAGCTGCCGG
NM_014869.5         CCAGACTACTGGGCCCTGGCCCACAAAGAGGACAAGGCTGACACGGACACGAGCTGCCGG
NM_001134382.2      CCAGACTACTGGGCCCTGGCCCACAAAGAGGACAAGGCTGACACGGACACGAGCTGCCGG
                    ************************************************************

HsCD00445243        AGCACGCCGTCGCTGGAGCGGCAGGNGCAGCGGCTGCGGGTGGAGCATCTGCCGCTGCTC
NM_014869.5         AGCACGCCGTCGCTGGAGCGGCAGGAGCAGCGGCTGCGGGTGGAGCATCTGCCGCTGCTC
NM_001134382.2      AGCACGCCGTCGCTGGAGCGGCAGGAGCAGCGGCTGCGGGTGGAGCATCTGCCGCTGCTC
                    ************************* **********************************

HsCD00445243        ACCATCGAGCCACCCAGCGACAGCTCTGTGGACCTTAGTGACCGCTCGGAGCGGGGGTCA
NM_014869.5         ACCATCGAGCCACCCAGCGACAGCTCTGTGGACCTTAGTGACCGCTCGGAGCGGGGGTCA
NM_001134382.2      ACCATCGAGCCACCCAGCGACAGCTCTGTGGACCTTAGTGACCGCTCGGAGCGGGGGTCA
                    ************************************************************

HsCD00445243        CTCAAGAGGCAGAGTGCTTACGAGCGCAGCCTTGGCGGGCAGCAGGGCAGTCCCAAGCAT
NM_014869.5         CTCAAGAGGCAGAGTGCTTACGAGCGCAGCCTTGGCGGGCAGCAGGGCAGTCCCAAGCAT
NM_001134382.2      CTCAAGAGGCAGAGTGCTTACGAGCGCAGCCTTGGCGGGCAGCAGGGCAGTCCCAAGCAT
                    ************************************************************

HsCD00445243        GGTCCCCACAGCGGCGCCCCCAAGAGCCTCCCCCGGGAGGAGCCTGAGTTGCGGCCCCGG
NM_014869.5         GGTCCCCACAGCGGCGCCCCCAAGAGCCTCCCCCGGGAGGAGCCTGAGTTGCGGCCCCGG
NM_001134382.2      GGTCCCCACAGCGGCGCCCCCAAGAGCCTCCCCCGGGAGGAGCCTGAGTTGCGGCCCCGG
                    ************************************************************

HsCD00445243        CCCCCCAGGCCCCTGGACAGCCACTTGGCCATCAATGGCTCAGCCAACCGGCAGAGCAAG
NM_014869.5         CCCCCCAGGCCCCTGGACAGCCACTTGGCCATCAATGGCTCAGCCAACCGGCAGAGCAAG
NM_001134382.2      CCCCCCAGGCCCCTGGACAGCCACTTGGCCATCAATGGCTCAGCCAACCGGCAGAGCAAG
                    ************************************************************

HsCD00445243        TCTGAGTCGGACTACTCAGACGGTGACAATGACAGCATCAACAGCACGTCCAACTCCAAC
NM_014869.5         TCTGAGTCGGACTACTCAGACGGTGACAATGACAGCATCAACAGCACGTCCAACTCCAAC
NM_001134382.2      TCTGAGTCGGACTACTCAGACGGTGACAATGACAGCATCAACAGCACGTCCAACTCCAAC
                    ************************************************************

HsCD00445243        GATACCATCAACTGCAGCTCCGAGTCATCGTCCCGTGACAGCCTGCGGGAGCAGACGCTC
NM_014869.5         GATACCATCAACTGCAGCTCCGAGTCATCGTCCCGTGACAGCCTGCGGGAGCAGACGCTC
NM_001134382.2      GATACCATCAACTGCAGCTCCGAGTCATCGTCCCGTGACAGCCTGCGGGAGCAGACGCTC
                    ************************************************************

HsCD00445243        AGCAAGCAGACCTACCACAAGGAGGCCCGCAACAGCTGGGACTCGCCTGCCTTTAGCAAC
NM_014869.5         AGCAAGCAGACCTACCACAAGGAGGCCCGCAACAGCTGGGACTCGCCTGCCTTTAGCAAC
NM_001134382.2      AGCAAGCAGACCTACCACAAGGAGGCCCGCAACAGCTGGGACTCGCCTGCCTTTAGCAAC
                    ************************************************************

HsCD00445243        GATGTCATCCGCAAGAGGCACTACCGCATCGGCCTGAACCTCTTCAACAAGAAGCCTGAG
NM_014869.5         GATGTCATCCGCAAGAGGCACTACCGCATCGGCCTGAACCTCTTCAACAAGAAGCCTGAG
NM_001134382.2      GATGTCATCCGCAAGAGGCACTACCGCATCGGCCTGAACCTCTTCAACAAGAAGCCTGAG
                    ************************************************************

HsCD00445243        AAGGGAGTCCAGTACCTCATCGAGCGTGGCTTTGTGCCCGACACGCCCGTCGGGGTGGCC
NM_014869.5         AAGGGAGTCCAGTACCTCATCGAGCGTGGCTTTGTGCCCGACACGCCCGTCGGGGTGGCC
NM_001134382.2      AAGGGAGTCCAGTACCTCATCGAGCGTGGCTTTGTGCCCGACACGCCCGTCGGGGTGGCC
                    ************************************************************

HsCD00445243        CACTTCCTGCTGCAGCGCAAGGGCCTCAGCCGGCAGATGATCGGCGAGTTCCTGGGCAAC
NM_014869.5         CACTTCCTGCTGCAGCGCAAGGGCCTCAGCCGGCAGATGATCGGCGAGTTCCTGGGCAAC
NM_001134382.2      CACTTCCTGCTGCAGCGCAAGGGCCTCAGCCGGCAGATGATCGGCGAGTTCCTGGGCAAC
                    ************************************************************

HsCD00445243        CGGCAGAAGCAGTTCAACCGTGACGTGCTCGACTGCGTCGTGGACGAGATGGACTTCTCT
NM_014869.5         CGGCAGAAGCAGTTCAACCGTGACGTGCTCGACTGCGTCGTGGACGAGATGGACTTCTCT
NM_001134382.2      CGGCAGAAGCAGTTCAACCGTGACGTGCTCGACTGCGTCGTGGACGAGATGGACTTCTCT
                    ************************************************************

HsCD00445243        ACCATGGAGCTGGATGAGGCCCTCAGGAAATTCCAGGCGCACATCCGTGTCCAAGGGGAG
NM_014869.5         ACCATGGAGCTGGATGAGGCCCTCAGGAAATTCCAGGCGCACATCCGTGTCCAAGGGGAG
NM_001134382.2      ACCATGGAGCTGGATGAGGCCCTCAGGAAATTCCAGGCGCACATCCGTGTCCAAGGGGAG
                    ************************************************************

HsCD00445243        GCTCAGAAAGTGGAGCGGCTCATAGAGGCGTTCAGCCAGCGCTACTGCATCTGCAACCCT
NM_014869.5         GCTCAGAAAGTGGAGCGGCTCATAGAGGCGTTCAGCCAGCGCTACTGCATCTGCAACCCT
NM_001134382.2      GCTCAGAAAGTGGAGCGGCTCATAGAGGCGTTCAGCCAGCGCTACTGCATCTGCAACCCT
                    ************************************************************

HsCD00445243        GGGGTGGTGCGGCAATTCCGGAACCCAGACACCATTTTCATCCTGGCCTTCGCCATCATC
NM_014869.5         GGGGTGGTGCGGCAATTCCGGAACCCAGACACCATTTTCATCCTGGCCTTCGCCATCATC
NM_001134382.2      GGGGTGGTGCGGCAATTCCGGAACCCAGACACCATTTTCATCCTGGCCTTCGCCATCATC
                    ************************************************************

HsCD00445243        CTGCTGAACACCGACATGTACAGCCCCAATGTCAAGCCCGAGCGGAAAATGAAGCTAGAG
NM_014869.5         CTGCTGAACACCGACATGTACAGCCCCAATGTCAAGCCCGAGCGGAAAATGAAGCTAGAG
NM_001134382.2      CTGCTGAACACCGACATGTACAGCCCCAATGTCAAGCCCGAGCGGAAAATGAAGCTAGAG
                    ************************************************************

HsCD00445243        GACTTCATCAAGAACCTCCGAGGTGTGGACGATGGTGAGGACATTCCCCGTGAGATGCTG
NM_014869.5         GACTTCATCAAGAACCTCCGAGGTGTGGACGATGGTGAGGACATTCCCCGTGAGATGCTG
NM_001134382.2      GACTTCATCAAGAACCTCCGAGGTGTGGACGATGGTGAGGACATTCCCCGTGAGATGCTG
                    ************************************************************

HsCD00445243        ATGGGGATCTATGAACGGATCCGTAAGCGAGAGCTAAAGACCAATGAGGACCATGTGTCC
NM_014869.5         ATGGGGATCTATGAACGGATCCGTAAGCGAGAGCTAAAGACCAATGAGGACCATGTGTCC
NM_001134382.2      ATGGGGATCTATGAACGGATCCGTAAGCGAGAGCTAAAGACCAATGAGGACCATGTGTCC
                    ************************************************************

HsCD00445243        CAGGTGCAGAAGGTGGAGAAGCTCATTGTGGGGAAAAAGCCGATCGGATCCCTGCATCCC
NM_014869.5         CAGGTGCAGAAGGTGGAGAAGCTCATTGTGGGGAAAAAGCCGATCGGATCCCTGCATCCC
NM_001134382.2      CAGGTGCAGAAGGTGGAGAAGCTCATTGTGGGGAAAAAGCCGATCGGATCCCTGCATCCC
                    ************************************************************

HsCD00445243        GGGCTCGGCTGTGTGCTCTCTCTGCCCCACCGTCGGTTGGTCTGCTACTGCCGGCTCTTT
NM_014869.5         GGGCTCGGCTGTGTGCTCTCTCTGCCCCACCGTCGGTTGGTCTGCTACTGCCGGCTCTTT
NM_001134382.2      GGGCTCGGCTGTGTGCTCTCTCTGCCCCACCGTCGGTTGGTCTGCTACTGCCGGCTCTTT
                    ************************************************************

HsCD00445243        GAGGTTCCAGACCCAAACAAGCCCCAGAAACTCGGACTACACCAGCGAGAAATCTTCCTG
NM_014869.5         GAGGTTCCAGACCCAAACAAGCCCCAGAAACTCGGACTACACCAGCGAGAAATCTTCCTG
NM_001134382.2      GAGGTTCCAGACCCAAACAAGCCCCAGAAACTCGGACTACACCAGCGAGAAATCTTCCTG
                    ************************************************************

HsCD00445243        TTCAACGACCTCCTGGTGGTCACCAAGATCTTCCAGAAGAAGAAGAACTCGGTGACGTAC
NM_014869.5         TTCAACGACCTCCTGGTGGTCACCAAGATCTTCCAGAAGAAGAAGAACTCGGTGACGTAC
NM_001134382.2      TTCAACGACCTCCTGGTGGTCACCAAGATCTTCCAGAAGAAGAAGAACTCGGTGACGTAC
                    ************************************************************

HsCD00445243        AGCTTCCGACAGTCCTTCTCCTTGTACGGCATGCAGGTCCTGCTCTTCGAGAACCAGTAC
NM_014869.5         AGCTTCCGACAGTCCTTCTCCTTGTACGGCATGCAGGTCCTGCTCTTCGAGAACCAGTAC
NM_001134382.2      AGCTTCCGACAGTCCTTCTCCTTGTACGGCATGCAGGTCCTGCTCTTCGAGAACCAGTAC
                    ************************************************************

HsCD00445243        TACCCCAATGGCATCCGGCTCACCTCGTCTGTCCCCGGAGCAGATATCAAAGTGTTAATA
NM_014869.5         TACCCCAATGGCATCCGGCTCACCTCGTCTGTCCCCGGAGCAGATATCAAAGTGTTAATA
NM_001134382.2      TACCCCAATGGCATCCGGCTCACCTCGTCTGTCCCCGGAGCAGATATCAAAGTGTTAATA
                    ************************************************************

HsCD00445243        AACTTCAACGCCCCCAACCCTCAAGACCGGAAGAAATTCACCGATGACCTGCGGGAGTCC
NM_014869.5         AACTTCAACGCCCCCAACCCTCAAGACCGGAAGAAATTCACCGATGACCTGCGGGAGTCC
NM_001134382.2      AACTTCAACGCCCCCAACCCTCAAGACCGGAAGAAATTCACCGATGACCTGCGGGAGTCC
                    ************************************************************

HsCD00445243        ATTGCGGAAGTCCAAGAGATGGAGAAGCACAGGATAGAGTCGGAGCTCGAGAAGCAGAAA
NM_014869.5         ATTGCGGAAGTCCAAGAGATGGAGAAGCACAGGATAGAGTCGGAGCTCGAGAAGCAGAAA
NM_001134382.2      ATTGCGGAAGTCCAAGAGATGGAGAAGCACAGGATAGAGTCGGAGCTCGAGAAGCAGAAA
                    ************************************************************

HsCD00445243        GGCGTCGTGCGGCCCAGCATGTCCCAGTGCTCTAGCCTCAAAAAGGAGTCGGGCAACGGA
NM_014869.5         GGCGTCGTGCGGCCCAGCATGTCCCAGTGCTCTAGCCTCAAAAAGGAGTCGGGCAACGGA
NM_001134382.2      GGCGTCGTGCGGCCCAGCATGTCCCAGTGCTCTAGCCTCAAAAAGGAGTCGGGCAACGGA
                    ************************************************************

HsCD00445243        ACACTGAGCCGGGCCTGCCTGGACGACAGCTATGCCAGCGGTGAGGGCCTCAAGCGCAGC
NM_014869.5         ACACTGAGCCGGGCCTGCCTGGACGACAGCTATGCCAGCGGTGAGGGCCTCAAGCGCAGC
NM_001134382.2      ACACTGAGCCGGGCCTGCCTGGACGACAGCTATGCCAGCGGTGAGGGCCTCAAGCGCAGC
                    ************************************************************

HsCD00445243        GCCCTCAGCAGCTCCCTGCGGGACCTCTCGGAAGCCGGGGTCCATCAT------------
NM_014869.5         GCCCTCAGCAGCTCCCTGCGGGACCTCTCGGAAGCCGGGAAGCGAGGGCGTCGCAGCAGT
NM_001134382.2      GCCCTCAGCAGCTCCCTGCGGGACCTCTCGGAAGCCGGGAAGCGAGGGCGTCGCAGCAGT
                    ***************************************.: *.: .             

HsCD00445243        ------------------------------------------------------------
NM_014869.5         GCGGGATCGCTAGAGAGCAATGTG--GAATTTCAGCCTTTCGAGCCACTGCAGCCGTCAG
NM_001134382.2      GCGGGATCGCTAGAGAGCAATGTGGAAGGGTCCATCATTAGCAGTCCTCACATGCGCCGG
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         TGCTGTGCTCCTAA----------------------------------------------
NM_001134382.2      AGAGCTACATCAACACGAGAGTGTCCATCTCGCCCACACCAGACTATGCCCAACTCATCT
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         ------------------------------------------------------------
NM_001134382.2      TCCCTCCTGGGCTCCTTATTCGGGAGCAAGAGAGGGAAGCCCCCTCCCCAGGCCCACCTG
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         ------------------------------------------------------------
NM_001134382.2      CCCTCAGCCCCAGCCCTGCCACCCCCCCACCCACCGGTGGTCCTGCCTCACTTGCAGCAC
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         ------------------------------------------------------------
NM_001134382.2      TCTGTGGCTGGCCACCACCTGGGGCCCCCAGAGGGGCTGCCGCAGGCCGCCATGCACGGG
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         ------------------------------------------------------------
NM_001134382.2      CATCACACCCAGTACTGCCACATGCAGAACCCTCCCCCGTACCACCATCACCACCACCAC
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         ------------------------------------------------------------
NM_001134382.2      CACCCACCCCAGCACATCCAGCACGCACACCAGTACCACCACGGCCCCCATGGGGGCCAC
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         ------------------------------------------------------------
NM_001134382.2      CCAGCCTACGGGGCCCATGCCCACGGCCACCCGCCGCTGCCCTCGGCCCACGTGGGGCAC
                                                                                

HsCD00445243        ------------------------------------------------------------
NM_014869.5         ------------------------------------------------------------
NM_001134382.2      ACAGTGCACCACCATGGGCAGCCCCCTGCCCCGCCGCCCCCCACCAGCAGCAAGGCCAAA
                                                                                

HsCD00445243        ---------------------------
NM_014869.5         ---------------------------
NM_001134382.2      CCCAGCGGCATCAGCACAATTGTGTAG
                                               

Pathways

NCI : Arf6 signaling events
NCI : Plexin-D1 Signaling
WikiPathway : EGF/EGFR Signaling Pathway

Protein

SMART domain : Sec7 : Sec7 domain
SMART domain : PH : Pleckstrin homology domain.
HPRD : 11052

Clone

Original Clone ID : ccsbBroad304_14033

Organism


TAX_ID : 9606
Species Specific ID: 9922

Genome

Chromosome : 3
Map Location : 3p25.2
Ensembl : ENSG00000144711

Reagents

Labome : IQSEC1-antibody