DNASU Plasmid | HERC5 (Homo sapiens) in pENTR223 (Gateway donor/master vector)

Explanation of Terms

Gene:

Gene Symbol: HERC5

Gene Name: HECT and RLD domain containing E3 ubiquitin protein ligase 5

Original Clone ID:

ccsbBroadEn_08246

Keyword:

None

Species:

Homo sapiens

Type:

cDNA

Vector Name:

pENTR223

Format:

FUSION

Source:

The ORFeome Collaboration

Description:

Original GenBank Accession: BC140716.1

Comments:

None

Mutation / Discrepancy:

No / No

Publications:

None

Authors:

Harvard Medical School
Dana-Farber Cancer Institute
Broad Institute of Harvard and Massachusetts Institute of Technology (MIT)
David E Hill
David E Root
The ORFeome Collaboration

HsCD00516476

Price:

AVAILABLE

No restriction
Special MTA: None

Insert Sequence
Protein Sequence

Insert sequence: 3072nts

Open reading frame: 1 to 3072

Reference Sequence Alignment

ATGGAGCGGAGGTCGCGGAGGAAGTCGCGGCGCAACGGGCGCTCGACCGCGGGCAAGGCC
GCCGCGACCCAGCCCGCGAAGTCTCCGGGCGCACAGCTCTGGCTCTTTCCCAGCGCCGCG
GGCCTCCACCGCGCGCTGCTCCGGAGGGTGGAGGTGACGCGCCAACTCTGCTGCTCGCCG
GGGCGCCTCGCGGTCTTGGAACGCGGCGGGGCGGGCGTCCAGGTTCACCAGCTGCTCGCC
GGGAGCGGCGGCGCCCGGACGCCGAAATGCATTAAATTAGGAAAAAACATGAAGATACAT
TCAGTGGACCAAGGAGCAGAGCACATGCTGATTCTCTCATCAGATGGAAAACCATTTGAG
TATGACAACTATAGCATGAAACATCTAAGGTTTGAAAGCATTTTACAAGAAAAAAAAATA
ATTCAGATCACATGTGGAGATTACCATTCTCTTGCACTCTCAAAAGGTGGTGAGCTTTTT
GCCTGGGGACAGAACCTGCATGGGCAGCTTGGAGTTGGAAGGAAATTTCCCTCAACCACC
ACACCACAGATTGTGGAGCACCTCGCAGGAGTACCCTTGGCTCAGATTTCTGCCGGAGAA
GCCCACAGCATGGCCTTATCCATGTCTGGCAACATTTATTCATGGGGAAAAAATGAATGT
GGACAACTAGGCCTGGGCCACACTGAGAGTAAAGATGATCCATCCCTTATTGAAGGACTA
GACAATCAGAAAGTTGAATTTGTCGCTTGTGGTGGCTCTCACAGTGCCCTACTCACACAG
GATGGGCTGCTGTTTACTTTCGGTGCTGGAAAACATGGGCAACTTGGTCATAATTCAACA
CAGAATGAGCTAAGACCCTGTTTGGTGGCTGAGCTTGTTGGGTATAGAGTGACTCAGATA
GCATGTGGAAGGTGGCACACACTTGCCTATGTTTCTGATTTGGGAAAGGTCTTTTCCTTT
GGTTCTGGAAAAGATGGACAACTGGGAAATGGTGGAACACGTGACCAGCTGATGCCGCTT
CCAGTGAAAGTATCATCAAGTGAAGAACTCAAACTTGAAAGCCATACCTCAGAAAAGGAG
TTAATAATGATTGCTGGAGGGAATCAAAGCATTTTGCTCTGGATAAAGAAAGAGAATTCA
TATGTTAATCTGAAGAGGACAATTCCTACTCTGAATGAAGGGACTGTAAAGAGATGGATT
GCTGATGTGGAGACTAAACGGTGGCAGAGCACAAAAAGGGAAATCCAAGAGATATTTTCA
TCTCCTGCTTGTCTAACTGGAAGTTTTTTAAGGAAAAGAAGAACTACAGAAATGATGCCT
GTTTATTTGGACTTAAATAAAGCAAGAAACATCTTCAAGGAGTTAACCCAAAAGGACTGG
ATTACTAACATGATAACCACCTGCCTCAAAGATAATCTGCTCAAAAGACTTCCATTTCAT
TCTCCACCCCAAGAAGCTTTAGAAATTTTCTTCCTTCTCCCAGAATGTCCTGTGATGCAT
ATTTCCAACAACTGGGAGAGCCTTGTGGTTCCATTTGCAAAGGTTGTTTGTAAAATGAGT
GACCAGTCTTCACTGGTTCTGGAAGAGTATTGGGCAACTCTGCAAGAATCCACTTTCAGC
AAACTGGTCCAGATGTTTAAAACAGCCGTCATATGCCAGTTGGATTACTGGGATGAAAGT
GCTGAGGAGAATGGTAATGTTCAAGCTCTCCTAGAAATGTTGAAGAAGCTGCACAGGGTA
AACCAGGTGAAATGTCAACTACCTGAAAGTATTTTCCAAGTAGACGAACTCTTGCACCGT
CTCAATTTTTTTGTAGAAGTATGCAGAAGGTACTTGTGGAAAATGACTGTGGACGCTTCA
GAAAATGTACAATGCTGCGTCATATTCAGTCACTTTCCATTTATCTTTAATAATCTGTCG
AAAATTAAACTACTACATACAGACACACTTTTAAAAATAGAGAGTAAAAAACATAAAGCT
TATCTTAGGTCGGCAGCAATTGAGGAAGAAAGAGAGTCTGAATTCGCTTTGAGGCCCACG
TTTGATCTAACAGTCAGAAGGAATCACTTGATTGAGGATGTTTTGAATCAGCTAAGTCAA
TTTGAGAATGAAGACCTGAGGAAAGAGTTATGGGTTTCATTTAGTGGAGAAATTGGGTAT
GACCTCGGAGGAGTCAAGAAAGAGTTCTTCTACTGTCTGTTTGCAGAGATGATCCAGCCG
GAATATGGGATGTTCATGTATCCTGAAGGGGCTTCCTGCATGTGGTTTCCTGTCAAGCCT
AAATTTGAGAAGAAAAGATACTTCTTTTTTGGGGTTCTATGTGGACTTTCCCTGTTCAAT
TGCAATGTTGCCAACCTCCCTTTCCCACTGGCACTGTTTAAGAAACTTTTGGACCAAATG
CCATCATTGGAAGACTTGAAAGAACTCAGTCCTGATTTGGGAAAGAATTTGCAAACACTT
CTGGATGATGAAGGTGATAACTTTGAGGAAGTATTTTACATCCATTTTAATGTGCACTGG
GACAGAAACGACACAAACTTAATTCCTAATGGAAGTAGCATAACTGTCAACCAGACTAAC
AAGAGAGACTATGTTTCTAAGTATATCAATTACATTTTCAACGACTCTGTAAAGGCGGTT
TATGAAGAATTTCGGAGAGGATTTTATAAAATGTGCGACGAAGACATTATCAAATTATTC
CACCCCGAAGAACTGAAGGATGTGATTGTTGGAAATACAGATTATGATTGGAAAACATTT
GAAAAGAATGCACGTTATGAACCAGGATATAACAGTTCACATCCCACCATAGTGATGTTT
TGGAAGGCTTTCCACAAATTGACTCTGGAAGAAAAGAAAAAATTCCTTGTATTTCTTACA
GGAACTGACAGACTACAAATGAAAGATTTAAATAATATGAAAATAACATTTTGCTGTCCT
GAAAGTTGGAATGAAAGAGACCCTATAAGAGCACTGACATGTTTCAGTGTCCTCTTCCTC
CCTAAATATTCTACAATGGAAACAGTTGAAGAAGCGCTTCAAGAAGCCATCAACAACAAC
AGAGGATTTGGC

Protein sequence predicted based on nucleotide sequence

MERRSRRKSRRNGRSTAGKAAATQPAKSPGAQLWLFPSAAGLHRALLRRVEVTRQLCCSP
GRLAVLERGGAGVQVHQLLAGSGGARTPKCIKLGKNMKIHSVDQGAEHMLILSSDGKPFE
YDNYSMKHLRFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTT
TPQIVEHLAGVPLAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGL
DNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQI
ACGRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSEELKLESHTSEKE
LIMIAGGNQSILLWIKKENSYVNLKRTIPTLNEGTVKRWIADVETKRWQSTKREIQEIFS
SPACLTGSFLRKRRTTEMMPVYLDLNKARNIFKELTQKDWITNMITTCLKDNLLKRLPFH
SPPQEALEIFFLLPECPVMHISNNWESLVVPFAKVVCKMSDQSSLVLEEYWATLQESTFS
KLVQMFKTAVICQLDYWDESAEENGNVQALLEMLKKLHRVNQVKCQLPESIFQVDELLHR
LNFFVEVCRRYLWKMTVDASENVQCCVIFSHFPFIFNNLSKIKLLHTDTLLKIESKKHKA
YLRSAAIEEERESEFALRPTFDLTVRRNHLIEDVLNQLSQFENEDLRKELWVSFSGEIGY
DLGGVKKEFFYCLFAEMIQPEYGMFMYPEGASCMWFPVKPKFEKKRYFFFGVLCGLSLFN
CNVANLPFPLALFKKLLDQMPSLEDLKELSPDLGKNLQTLLDDEGDNFEEVFYIHFNVHW
DRNDTNLIPNGSSITVNQTNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDIIKLF
HPEELKDVIVGNTDYDWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLT
GTDRLQMKDLNNMKITFCCPESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNN
RGFG

Coding Sequence Details

Insert Sequence Verified?:

Verification Method:

Verified by the ORFeome collaboration

Mutations:

None

Discrepancy:

None

5' Linker Sequence:

None

3' Linker Sequence:

None

Recommended Growth Condition:

Distributed in bacterial strain:

DH5-alpha T1 phage resistant

Antibiotic Selection:

Host Type: bacterial Marker: spectinomycin

Bacterial Selection Condition: 100 ug/mL spectinomycin

Growth Condition: Growth at 37 degrees C in LB supplemented with 100 ug/mL spectinomycin.

Comments: None

Protein Expression Results:

None

Recommended expression in:

Not Applicable

Vector Name:

pENTR223

Synonyms:

pDONR223, pENTR223-XnCDSYn

Sequencing Primer:

Forward: M13F

Reverse: M13R

Description:

Gateway type (lambda att-type) recombinational cloning entry (master) vector; spectinomycin resistance; recombinational cloning.

Comments:

Additional information about this vector is available from the commercial website and at the ORFeome website http://orfeomecollaboration.org/vectors.php; also see supplemental figure 1 of the paper PubMed ID 15489335.

Size (bp):

2815

Parent Vector:

None

Properties:

Gateway, donor (entry), recombinational cloning

Author Name:

Mark Vidal

Publications:

PMID: 15489335

Title: Human ORFeome Version 1.1: A Platform for Reverse Proteomics

Vector Map:

Vector Sequence:

Sequence:

CTTTCCTGCGTTATCCCCTGATTCTGTGGATAACCGTATTACCGCCTTTGAGTGAGCTGATACCGCTCGCCGCAGCCGAACGACCGAGCGCAGCGAGTCAGTGAGCGAGGAAGCGGAAGAGCGCCCAATACGCAAACCGCCTCTCCCCGCGCGTTGGCCGATTCATTAATGCAGCTGGCACGACAGGTTTCCCGACTGGAAAGCGGGCAGTGAGCGCAACGCAATTAATACGCGTACCGCTAGCCAGGAAGAGTTTGTAGAAACGCAAAAAGGCCATCCGTCAGGATGGCCTTCTGCTTAGTTTGATGCCTGGCAGTTTATGGCGGGCGTCCTGCCCGCCACCCTCCGGGCCGTTGCTTCACAACGTTCAAATCCGCTCCCGGCGGATTTGTCCTACTCAGGAGAGCGTTCACCGACAAACAACAGATAAAACGAAAGGCCCAGTCTTCCGACTGAGCCTTTCGTTTTATTTGATGCCTGGCAGTTCCCTACTCTCGCGTTAACGCTAGCATGGATGTTTTCCCAGTCACGACGTTGTAAAACGACGGCCAGTCTTAAGCTCGGGCCCCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATGAGCAATGCTTTTTTATAATGCCAACTTTGTACAAAAAAGTTGCCAACTTTCTTGTACAAAGTTGGCATTATAAGAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGCCATCCAGCTGATATCCCCTATAGTGAGTCGTATTACATGGTCATAGCTGTTTCCTGGCAGCTCTGGCCCGTGTCTCAAAATCTCTGATGTTACATTGCACAAGATAAAAATATATCATCATGCCTCCTCTAGACCAGCCAGGACAGAAATGCCTCGACTTCGCTGCTACCCAAGGTTGCCGGGTGACGCACACCGTGGAAACGGATGAAGGCACGAACCCAGTGGACATAAGCCTGTTCGGTTCGTAAGCTGTAATGCAAGTAGCGTATGCGCTCACGCAACTGGTCCAGAACCTTGACCGAACGCAGCGGTGGTAACGGCGCAGTGGCGGTTTTCATGGCTTGTTATGACTGTTTTTTTGGGGTACAGTCTATGCCTCGGGCATCCAAGCAGCAAGCGCGTTACGCCGTGGGTCGATGTTTGATGTTATGGAGCAGCAACGATGTTACGCAGCAGGGCAGTCGCCCTAAAACAAAGTTAAACATCATGAGGGAAGCGGTGATCGCCGAAGTATCGACTCAACTATCAGAGGTAGTTGGCGTCATCGAGCGCCATCTCGAACCGACGTTGCTGGCCGTACATTTGTACGGCTCCGCAGTGGATGGCGGCCTGAAGCCACACAGTGATATTGATTTGCTGGTTACGGTGACCGTAAGGCTTGATGAAACAACGCGGCGAGCTTTGATCAACGACCTTTTGGAAACTTCGGCTTCCCCTGGAGAGAGCGAGATTCTCCGCGCTGTAGAAGTCACCATTGTTGTGCACGACGACATCATTCCGTGGCGTTATCCAGCTAAGCGCGAACTGCAATTTGGAGAATGGCAGCGCAATGACATTCTTGCAGGTATCTTCGAGCCAGCCACGATCGACATTGATCTGGCTATCTTGCTGACAAAAGCAAGAGAACATAGCGTTGCCTTGGTAGGTCCAGCGGCGGAGGAACTCTTTGATCCGGTTCCTGAACAGGATCTATTTGAGGCGCTAAATGAAACCTTAACGCTATGGAACTCGCCGCCCGACTGGGCTGGCGATGAGCGAAATGTAGTGCTTACGTTGTCCCGCATTTGGTACAGCGCAGTAACCGGCAAAATCGCGCCGAAGGATGTCGCTGCCGACTGGGCAATGGAGCGCCTGCCGGCCCAGTATCAGCCCGTCATACTTGAAGCTAGACAGGCTTATCTTGGACAAGAAGAAGATCGCTTGGCCTCGCGCGCAGATCAGTTGGAAGAATTTGTCCACTACGTGAAAGGCGAGATCACCAAGGTAGTCGGCAAATAACCCTCGAGCCACCCATGACCAAAATCCCTTAACGTGAGTTACGCGTCGTTCCACTGAGCGTCAGACCCCGTAGAAAAGATCAAAGGATCTTCTTGAGATCCTTTTTTTCTGCGCGTAATCTGCTGCTTGCAAACAAAAAAACCACCGCTACCAGCGGTGGTTTGTTTGCCGGATCAAGAGCTACCAACTCTTTTTCCGAAGGTAACTGGCTTCAGCAGAGCGCAGATACCAAATACTGTCCTTCTAGTGTAGCCGTAGTTAGGCCACCACTTCAAGAACTCTGTAGCACCGCCTACATACCTCGCTCTGCTAATCCTGTTACCAGTGGCTGCTGCCAGTGGCGATAAGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACGGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACTGAGATACCTACAGCGTGAGCATTGAGAAAGCGCCACGCTTCCCGAAGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGCGCACGAGGGAGCTTCCAGGGGGAAACGCCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGACTTGAGCGTCGATTTTTGTGATGCTCGTCAGGGGGGCGGAGCCTATGGAAAAACGCCAGCAACGCGGCCTTTTTACGGTTCCTGGCCTTTTGCTGGCCTTTTGCTCACATGTT

Vector Features:

Type

Name

Description

Start

End

bacterial origin

ori

bacterial origin of replication

2220

2753

gene fragment

pas

5p stem of pBR primose assembly site

gene fragment

pas prime

3p stem of pBR pas(L)

105

116

recombination site

attL1

attL1 recombination site

570

665

recombination site

attL2

attL2 recombination site

793

696

selectable marker

SpnR

spectinomycin resistance gene

1062

2072

trxn termination sequence

T1-T2

rrnBT1 and T2 terminators

510

224

Gene

Gene Symbol :

HERC5

Symbol Nomenclature :

HERC5

SYNONYM :

CEB1; CEBP1

Designation :

E3 ISG15-protein ligase HERC5|HECT domain and RCC1-like domain-containing protein 5|cyclin-E-binding protein 1|hect domain and RLD 5|probable E3 ubiquitin-protein ligase HERC5

Full Nomenclature :

HECT and RLD domain containing E3 ubiquitin protein ligase 5

GENEID :

51191

HGNC :

24368

MIM :

608242

Vega :

OTTHUMG00000130953

Target GenBank:

None

Reference Sequence Alignment

  

HsCD00516476      ATGGAGCGGAGGTCGCGGAGGAAGTCGCGGCGCAACGGGCGCTCGACCGCGGGCAAGGCC
NM_016323.3       ATGGAGCGGAGGTCGCGGAGGAAGTCGCGGCGCAACGGGCGCTCGACCGCGGGCAAGGCC
                  ************************************************************

HsCD00516476      GCCGCGACCCAGCCCGCGAAGTCTCCGGGCGCACAGCTCTGGCTCTTTCCCAGCGCCGCG
NM_016323.3       GCCGCGACCCAGCCCGCGAAGTCTCCGGGCGCACAGCTCTGGCTCTTTCCCAGCGCCGCG
                  ************************************************************

HsCD00516476      GGCCTCCACCGCGCGCTGCTCCGGAGGGTGGAGGTGACGCGCCAACTCTGCTGCTCGCCG
NM_016323.3       GGCCTCCACCGCGCGCTGCTCCGGAGGGTGGAGGTGACGCGCCAACTCTGCTGCTCGCCG
                  ************************************************************

HsCD00516476      GGGCGCCTCGCGGTCTTGGAACGCGGCGGGGCGGGCGTCCAGGTTCACCAGCTGCTCGCC
NM_016323.3       GGGCGCCTCGCGGTCTTGGAACGCGGCGGGGCGGGCGTCCAGGTTCACCAGCTGCTCGCC
                  ************************************************************

HsCD00516476      GGGAGCGGCGGCGCCCGGACGCCGAAATGCATTAAATTAGGAAAAAACATGAAGATACAT
NM_016323.3       GGGAGCGGCGGCGCCCGGACGCCGAAATGCATTAAATTAGGAAAAAACATGAAGATACAT
                  ************************************************************

HsCD00516476      TCAGTGGACCAAGGAGCAGAGCACATGCTGATTCTCTCATCAGATGGAAAACCATTTGAG
NM_016323.3       TCCGTGGACCAAGGAGCAGAGCACATGCTGATTCTCTCATCAGATGGAAAACCATTTGAG
                  **.*********************************************************

HsCD00516476      TATGACAACTATAGCATGAAACATCTAAGGTTTGAAAGCATTTTACAAGAAAAAAAAATA
NM_016323.3       TATGACAACTATAGCATGAAACATCTAAGGTTTGAAAGCATTTTACAAGAAAAAAAAATA
                  ************************************************************

HsCD00516476      ATTCAGATCACATGTGGAGATTACCATTCTCTTGCACTCTCAAAAGGTGGTGAGCTTTTT
NM_016323.3       ATTCAGATCACATGTGGAGATTACCATTCTCTTGCACTCTCAAAAGGTGGTGAGCTTTTT
                  ************************************************************

HsCD00516476      GCCTGGGGACAGAACCTGCATGGGCAGCTTGGAGTTGGAAGGAAATTTCCCTCAACCACC
NM_016323.3       GCCTGGGGACAGAACCTGCATGGGCAGCTTGGAGTTGGAAGGAAATTTCCCTCAACCACC
                  ************************************************************

HsCD00516476      ACACCACAGATTGTGGAGCACCTCGCAGGAGTACCCTTGGCTCAGATTTCTGCCGGAGAA
NM_016323.3       ACACCACAGATTGTGGAGCACCTCGCAGGAGTACCCTTGGCTCAGATTTCTGCCGGAGAA
                  ************************************************************

HsCD00516476      GCCCACAGCATGGCCTTATCCATGTCTGGCAACATTTATTCATGGGGAAAAAATGAATGT
NM_016323.3       GCCCACAGCATGGCCTTATCCATGTCTGGCAACATTTATTCATGGGGAAAAAATGAATGT
                  ************************************************************

HsCD00516476      GGACAACTAGGCCTGGGCCACACTGAGAGTAAAGATGATCCATCCCTTATTGAAGGACTA
NM_016323.3       GGACAACTAGGCCTGGGCCACACTGAGAGTAAAGATGATCCATCCCTTATTGAAGGACTA
                  ************************************************************

HsCD00516476      GACAATCAGAAAGTTGAATTTGTCGCTTGTGGTGGCTCTCACAGTGCCCTACTCACACAG
NM_016323.3       GACAATCAGAAAGTTGAATTTGTCGCTTGTGGTGGCTCTCACAGTGCCCTACTCACACAG
                  ************************************************************

HsCD00516476      GATGGGCTGCTGTTTACTTTCGGTGCTGGAAAACATGGGCAACTTGGTCATAATTCAACA
NM_016323.3       GATGGGCTGCTGTTTACTTTCGGTGCTGGAAAACATGGGCAACTTGGTCATAATTCAACA
                  ************************************************************

HsCD00516476      CAGAATGAGCTAAGACCCTGTTTGGTGGCTGAGCTTGTTGGGTATAGAGTGACTCAGATA
NM_016323.3       CAGAATGAGCTAAGACCCTGTTTGGTGGCTGAGCTTGTTGGGTATAGAGTGACTCAGATA
                  ************************************************************

HsCD00516476      GCATGTGGAAGGTGGCACACACTTGCCTATGTTTCTGATTTGGGAAAGGTCTTTTCCTTT
NM_016323.3       GCATGTGGAAGGTGGCACACACTTGCCTATGTTTCTGATTTGGGAAAGGTCTTTTCCTTT
                  ************************************************************

HsCD00516476      GGTTCTGGAAAAGATGGACAACTGGGAAATGGTGGAACACGTGACCAGCTGATGCCGCTT
NM_016323.3       GGTTCTGGAAAAGATGGACAACTGGGAAATGGTGGAACACGTGACCAGCTGATGCCGCTT
                  ************************************************************

HsCD00516476      CCAGTGAAAGTATCATCAAGTGAAGAACTCAAACTTGAAAGCCATACCTCAGAAAAGGAG
NM_016323.3       CCAGTGAAAGTATCATCAAGTGAAGAACTCAAACTTGAAAGCCATACCTCAGAAAAGGAG
                  ************************************************************

HsCD00516476      TTAATAATGATTGCTGGAGGGAATCAAAGCATTTTGCTCTGGATAAAGAAAGAGAATTCA
NM_016323.3       TTAATAATGATTGCTGGAGGGAATCAAAGCATTTTGCTCTGGATAAAGAAAGAGAATTCA
                  ************************************************************

HsCD00516476      TATGTTAATCTGAAGAGGACAATTCCTACTCTGAATGAAGGGACTGTAAAGAGATGGATT
NM_016323.3       TATGTTAATCTGAAGAGGACAATTCCTACTCTGAATGAAGGGACTGTAAAGAGATGGATT
                  ************************************************************

HsCD00516476      GCTGATGTGGAGACTAAACGGTGGCAGAGCACAAAAAGGGAAATCCAAGAGATATTTTCA
NM_016323.3       GCTGATGTGGAGACTAAACGGTGGCAGAGCACAAAAAGGGAAATCCAAGAGATATTTTCA
                  ************************************************************

HsCD00516476      TCTCCTGCTTGTCTAACTGGAAGTTTTTTAAGGAAAAGAAGAACTACAGAAATGATGCCT
NM_016323.3       TCTCCTGCTTGTCTAACTGGAAGTTTTTTAAGGAAAAGAAGAACTACAGAAATGATGCCT
                  ************************************************************

HsCD00516476      GTTTATTTGGACTTAAATAAAGCAAGAAACATCTTCAAGGAGTTAACCCAAAAGGACTGG
NM_016323.3       GTTTATTTGGACTTAAATAAAGCAAGAAACATCTTCAAGGAGTTAACCCAAAAGGACTGG
                  ************************************************************

HsCD00516476      ATTACTAACATGATAACCACCTGCCTCAAAGATAATCTGCTCAAAAGACTTCCATTTCAT
NM_016323.3       ATTACTAACATGATAACCACCTGCCTCAAAGATAATCTGCTCAAAAGACTTCCATTTCAT
                  ************************************************************

HsCD00516476      TCTCCACCCCAAGAAGCTTTAGAAATTTTCTTCCTTCTCCCAGAATGTCCTGTGATGCAT
NM_016323.3       TCTCCACCCCAAGAAGCTTTAGAAATTTTCTTCCTTCTCCCAGAATGTCCTATGATGCAT
                  ***************************************************.********

HsCD00516476      ATTTCCAACAACTGGGAGAGCCTTGTGGTTCCATTTGCAAAGGTTGTTTGTAAAATGAGT
NM_016323.3       ATTTCCAACAACTGGGAGAGCCTTGTGGTTCCATTTGCAAAGGTTGTTTGTAAAATGAGT
                  ************************************************************

HsCD00516476      GACCAGTCTTCACTGGTTCTGGAAGAGTATTGGGCAACTCTGCAAGAATCCACTTTCAGC
NM_016323.3       GACCAGTCTTCACTGGTTCTGGAAGAGTATTGGGCAACTCTGCAAGAATCCACTTTCAGC
                  ************************************************************

HsCD00516476      AAACTGGTCCAGATGTTTAAAACAGCCGTCATATGCCAGTTGGATTACTGGGATGAAAGT
NM_016323.3       AAACTGGTCCAGATGTTTAAAACAGCCGTCATATGCCAGTTGGATTACTGGGATGAAAGT
                  ************************************************************

HsCD00516476      GCTGAGGAGAATGGTAATGTTCAAGCTCTCCTAGAAATGTTGAAGAAGCTGCACAGGGTA
NM_016323.3       GCTGAGGAGAATGGTAATGTTCAAGCTCTCCTAGAAATGTTGAAGAAGCTGCACAGGGTA
                  ************************************************************

HsCD00516476      AACCAGGTGAAATGTCAACTACCTGAAAGTATTTTCCAAGTAGACGAACTCTTGCACCGT
NM_016323.3       AACCAGGTGAAATGTCAACTACCTGAAAGTATTTTCCAAGTAGACGAACTCTTGCACCGT
                  ************************************************************

HsCD00516476      CTCAATTTTTTTGTAGAAGTATGCAGAAGGTACTTGTGGAAAATGACTGTGGACGCTTCA
NM_016323.3       CTCAATTTTTTTGTAGAAGTATGCAGAAGGTACTTGTGGAAAATGACTGTGGACGCTTCA
                  ************************************************************

HsCD00516476      GAAAATGTACAATGCTGCGTCATATTCAGTCACTTTCCATTTATCTTTAATAATCTGTCG
NM_016323.3       GAAAATGTACAATGCTGCGTCATATTCAGTCACTTTCCATTTATCTTTAATAATCTGTCG
                  ************************************************************

HsCD00516476      AAAATTAAACTACTACATACAGACACACTTTTAAAAATAGAGAGTAAAAAACATAAAGCT
NM_016323.3       AAAATTAAACTACTACATACAGACACACTTTTAAAAATAGAGAGTAAAAAACATAAAGCT
                  ************************************************************

HsCD00516476      TATCTTAGGTCGGCAGCAATTGAGGAAGAAAGAGAGTCTGAATTCGCTTTGAGGCCCACG
NM_016323.3       TATCTTAGGTCGGCAGCAATTGAGGAAGAAAGAGAGTCTGAATTCGCTTTGAGGCCCACG
                  ************************************************************

HsCD00516476      TTTGATCTAACAGTCAGAAGGAATCACTTGATTGAGGATGTTTTGAATCAGCTAAGTCAA
NM_016323.3       TTTGATCTAACAGTCAGAAGGAATCACTTGATTGAGGATGTTTTGAATCAGCTAAGTCAA
                  ************************************************************

HsCD00516476      TTTGAGAATGAAGACCTGAGGAAAGAGTTATGGGTTTCATTTAGTGGAGAAATTGGGTAT
NM_016323.3       TTTGAGAATGAAGACCTGAGGAAAGAGTTATGGGTTTCATTTAGTGGAGAAATTGGGTAT
                  ************************************************************

HsCD00516476      GACCTCGGAGGAGTCAAGAAAGAGTTCTTCTACTGTCTGTTTGCAGAGATGATCCAGCCG
NM_016323.3       GACCTCGGAGGAGTCAAGAAAGAGTTCTTCTACTGTCTGTTTGCAGAGATGATCCAGCCG
                  ************************************************************

HsCD00516476      GAATATGGGATGTTCATGTATCCTGAAGGGGCTTCCTGCATGTGGTTTCCTGTCAAGCCT
NM_016323.3       GAATATGGGATGTTCATGTATCCTGAAGGGGCTTCCTGCATGTGGTTTCCTGTCAAGCCT
                  ************************************************************

HsCD00516476      AAATTTGAGAAGAAAAGATACTTCTTTTTTGGGGTTCTATGTGGACTTTCCCTGTTCAAT
NM_016323.3       AAATTTGAGAAGAAAAGATACTTCTTTTTTGGGGTTCTATGTGGACTTTCCCTGTTCAAT
                  ************************************************************

HsCD00516476      TGCAATGTTGCCAACCTCCCTTTCCCACTGGCACTGTTTAAGAAACTTTTGGACCAAATG
NM_016323.3       TGCAATGTTGCCAACCTTCCTTTCCCACTGGCACTGTTTAAGAAACTTTTGGACCAAATG
                  ***************** ******************************************

HsCD00516476      CCATCATTGGAAGACTTGAAAGAACTCAGTCCTGATTTGGGAAAGAATTTGCAAACACTT
NM_016323.3       CCATCATTGGAAGACTTGAAAGAACTCAGTCCTGATTTGGGAAAGAATTTGCAAACACTT
                  ************************************************************

HsCD00516476      CTGGATGATGAAGGTGATAACTTTGAGGAAGTATTTTACATCCATTTTAATGTGCACTGG
NM_016323.3       CTGGATGATGAAGGTGATAACTTTGAGGAAGTATTTTACATCCATTTTAATGTGCACTGG
                  ************************************************************

HsCD00516476      GACAGAAACGACACAAACTTAATTCCTAATGGAAGTAGCATAACTGTCAACCAGACTAAC
NM_016323.3       GACAGAAACGACACAAACTTAATTCCTAATGGAAGTAGCATAACTGTCAACCAGACTAAC
                  ************************************************************

HsCD00516476      AAGAGAGACTATGTTTCTAAGTATATCAATTACATTTTCAACGACTCTGTAAAGGCGGTT
NM_016323.3       AAGAGAGACTATGTTTCTAAGTATATCAATTACATTTTCAACGACTCTGTAAAGGCGGTT
                  ************************************************************

HsCD00516476      TATGAAGAATTTCGGAGAGGATTTTATAAAATGTGCGACGAAGACATTATCAAATTATTC
NM_016323.3       TATGAAGAATTTCGGAGAGGATTTTATAAAATGTGCGACGAAGACATTATCAAATTATTC
                  ************************************************************

HsCD00516476      CACCCCGAAGAACTGAAGGATGTGATTGTTGGAAATACAGATTATGATTGGAAAACATTT
NM_016323.3       CACCCCGAAGAACTGAAGGATGTGATTGTTGGAAATACAGATTATGATTGGAAAACATTT
                  ************************************************************

HsCD00516476      GAAAAGAATGCACGTTATGAACCAGGATATAACAGTTCACATCCCACCATAGTGATGTTT
NM_016323.3       GAAAAGAATGCACGTTATGAACCAGGATATAACAGTTCACATCCCACCATAGTGATGTTT
                  ************************************************************

HsCD00516476      TGGAAGGCTTTCCACAAATTGACTCTGGAAGAAAAGAAAAAATTCCTTGTATTTCTTACA
NM_016323.3       TGGAAGGCTTTCCACAAATTGACTCTGGAAGAAAAGAAAAAATTCCTTGTATTTCTTACA
                  ************************************************************

HsCD00516476      GGAACTGACAGACTACAAATGAAAGATTTAAATAATATGAAAATAACATTTTGCTGTCCT
NM_016323.3       GGAACTGACAGACTACAAATGAAAGATTTAAATAATATGAAAATAACATTTTGCTGTCCT
                  ************************************************************

HsCD00516476      GAAAGTTGGAATGAAAGAGACCCTATAAGAGCACTGACATGTTTCAGTGTCCTCTTCCTC
NM_016323.3       GAAAGTTGGAATGAAAGAGACCCTATAAGAGCACTGACATGTTTCAGTGTCCTCTTCCTC
                  ************************************************************

HsCD00516476      CCTAAATATTCTACAATGGAAACAGTTGAAGAAGCGCTTCAAGAAGCCATCAACAACAAC
NM_016323.3       CCTAAATATTCTACAATGGAAACAGTTGAAGAAGCGCTTCAAGAAGCCATCAACAACAAC
                  ************************************************************

HsCD00516476      AGAGGATTTGGC---
NM_016323.3       AGAGGATTTGGCTGA
                  ************

Pathways

Reactome :

Antiviral mechanism by IFN-stimulated genes

Reactome :

Cytokine Signaling in Immune system

Reactome :

Immune System

Reactome :

Innate Immune System

Reactome :

Interferon Signaling

Reactome :

ISG15 antiviral mechanism

Reactome :

Negative regulators of RIG-I/MDA5 signaling

Reactome :

RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways

Protein

SMART domain :

HECTc : Domain Homologous to E6-AP Carboxyl Terminus with

HPRD :

10502

Clone

Cloning Information :

667519

Original Clone ID :

ccsbBroadEn_08246

Organism

Species Specific ID:

51191

Genome

Chromosome :

Map Location :

4q22.1

Ensembl :

ENSG00000138646

Reagents

Labome :

HERC5-antibody