Publications

PMID: 37207905
Geddes, J. W., Bondada, V., Croall, D. E., Rodgers, D. W., & Gal, J. (2023). Impaired activity and membrane association of most calpain-5 mutants causal for neovascular inflammatory vitreoretinopathy. Biochimica et biophysica acta. Molecular basis of disease, 1869(6), 166747. https://doi.org/10.1016/j.bbadis.2023.166747

PMID: 35167828
Qiu J, Engelbrektson A, Song L, et al. Comparative Analysis of Antimicrobial Antibodies between Mild and Severe COVID-19 [published online ahead of print, 2023 Jun 6]. Microbiol Spectr. 2023;e0469022.

PMID: 37283053
Wang, C., Ulryck, N., Herzel, L., Pythoud, N., Kleiber, N., Guérineau, V., Jactel, V., Moritz, C., Bohnsack, M. T., Carapito, C., Touboul, D., Bohnsack, K. E., & Graille, M. (2023). N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing. Nucleic acids research, gkad487. Advance online publication. https://doi.org/10.1093/nar/gkad487

PMID: 37311461
Yiu, S. P. T., Zerbe, C., Vanderwall, D., Huttlin, E. L., Weekes, M. P., & Gewurz, B. E. (2023). An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation. Molecular cell, S1097-2765(23)00374-X. Advance online publication. https://doi.org/10.1016/j.molcel.2023.05.018

PMID: 37316655
Zhang, T., Rawal, Y., Jiang, H., Kwon, Y., Sung, P., & Greenberg, R. A. (2023). Break-induced replication orchestrates resection-dependent template switching. Nature, 10.1038/s41586-023-06177-3. Advance online publication. https://doi.org/10.1038/s41586-023-06177-3

Chien, Y.-C., Wang, Y.-S., Sridharan, D., Kuo, C.-W., Chien, C.-T., Uchihashi, T., Kato, K., Angata, T., Meng, T.-C., Hsu, S.-T. D., & Khoo, K.-H. (2023). High density of N- and O-glycosylation shields and defines the structural dynamics of the intrinsically disordered ectodomain of receptor-type protein tyrosine phosphatase alpha. JACS Au.https://doi.org/10.1021/jacsau.3c00124

PMID: 37356718
Hernandez, L. M., Montersino, A., Niu, J., Guo, S., Faezov, B., Sanders, S. S., Dunbrack, R. L., & Thomas, G. M. (2023). Palmitoylation-dependent control of JAK1 kinase signaling governs responses to neuropoietic cytokines and survival in DRG neurons. The Journal of biological chemistry, 104965. Advance online publication. https://doi.org/10.1016/j.jbc.2023.104965

Fehilly, J. D., Ward, R., Sánchez, A. G., Strachan, E., Ruddin, G., Collery, R. F., & Kennedy, B. N. (2023, June 1). Ocular phenotypes in CRISPR RLBP1B-/- zebrafish provide a screening platform for evaluating the pathogenicity of human RLBP1 variants using humanised transgenic lines. Investigative Ophthalmology & Visual Science. https://iovs.arvojournals.org/article.aspx?articleid=2788840

PMID: 37253003
Boese, A. C., Kang, J., Hwang, J. S., Kim, J., Eun, K., Malin, C. M., Magliocca, K. R., Pan, C., Jin, L., & Kang, S. (2023). Succinyl-CoA ligase ADP-forming subunit beta promotes stress granule assembly to regulate redox and drive cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America, 120(23), e2217332120. https://doi.org/10.1073/pnas.2217332120

PMID: 37146150
Zhang, T., Pang, W., Feng, T., Guo, J., Wu, K., Nunez Santos, M., Arthanarisami, A., Nana, A. L., Nguyen, Q., Kim, P. J., Jankowsky, J. L., Seeley, W. W., & Hu, F. (2023). TMEM106B regulates microglial proliferation and survival in response to demyelination. Science advances,9 (18), eadd2676. https://doi.org/10.1126/sciadv.add2676

PMID: 37164154
Ruiz, M., Devkota, R., Kaper, D., Ruhanen, H., Busayavalasa, K., Radović, U., Henricsson M., Käkelä R., Borén J., & Pilon, M. (2023). AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity. The Journal of biological chemistry,299(6), 104799. Advance online publication. https://doi.org/10.1016/j.jbc.2023.104799

PMID: 37166992
Dunker, W., Zaver, S. A., Pineda, J. M. B., Howard, C. J., Bradley, R. K., & Woodward, J. J. (2023). The proto-oncogene SRC phosphorylates cGAS to inhibit an anti-tumor immune response. JCI insight, e167270. Advance online publication. https://doi.org/10.1172/jci.insight.167270

PMID: 37200262
Brautigam, C. A., Deka, R. K., Tso, S. C., Liu, W. Z., & Norgard, M. V. (2023). Biophysical and biochemical studies support TP0094 as a phosphotransacetylase in an acetogenic energy-conservation pathway in Treponema pallidum. PloS one, 18(5), e0283952. https://doi.org/10.1371/journal.pone.0283952

PMID: 37202521
Kadirvelraj, R., Boruah, B. M., Wang, S., Chapla, D., Huang, C., Ramiah, A., Hudson, K. L., Prudden, A. R., Boons, G. J., Withers, S. G., Wood, Z. A., & Moremen, K. W. (2023). Structural basis for Lewis antigen synthesis by the α1,3-fucosyltransferase FUT9. Nature chemical biology, 10.1038/s41589-023-01345-y. Advance online publication. https://doi.org/10.1038/s41589-023-01345-y

PMID: 37075745
Li, M., Yang, L., Chan, A. K. N., Pokharel, S. P., Liu, Q., Mattson, N., Xu, X., Chang, W. H., Miyashita, K., Singh, P., Zhang, L., Li, M., Wu, J., Wang, J., Chen, B., Chan, L. N., Lee, J., Zhang, X. H., Rosen, S. T., Müschen M., Chen, C. W. (2023). Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1-EEF1A1 Axis. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10, (17), e2206584. https://doi.org/10.1002/advs.202206584

PMID: 37075122
Mukhopadhyay, S., Encarnación-Rosado, J., Lin, E. Y., Sohn, A. S. W., Zhang, H., Mancias, J. D., & Kimmelman, A. C. (2023). Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer. Science advances,9 (16), eadf9284. https://doi.org/10.1126/sciadv.adf9284

PMID: 37061542
Tang, H. W., Spirohn, K., Hu, Y., Hao, T., Kovács, I. A., Gao, Y., Binari, R., Yang-Zhou, D., Wan, K. H., Bader, J. S., Balcha, D., Bian, W., Booth, B. W., Coté, A. G., de Rouck, S., Desbuleux, A., Goh, K. Y., Kim, D. K., Knapp, J. J., Lee, W. X., … Mohr, S. E. (2023). Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Nature communications,14(1), 2162. https://doi.org/10.1038/s41467-023-37876-0

PMID: 37057874
Tran, G. B., Ding, J., Ye, B., Liu, M., Yu, Y., Zha, Y., Dong, Z., Liu, K., Sudarshan, S., & Ding, H. F. (2023). Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma. Cancer research, CAN-22-3450. Advance online publication. https://doi.org/10.1158/0008-5472.CAN-22-3450

PMID: 36690178
Pena-Martinez, E. G., Rivera-Madera, A., Pomales-Matos, D. A., Sanabria-Alberto, L., Rosario-Canuelas, B. M., Rodriguez-Rios, J. M., Carrasquillo-Dones, E. A., & Rodriguez-Martinez, J. A. (2023). Disease-associated non-coding variants alter NKX2-5 DNA-binding affinity. Biochimica et biophysica acta. Gene regulatory mechanisms, 1866(1), 194906. https://doi.org/10.1016/j.bbagrm.2023.194906

PMID: 36652335
Palicharla, V. R., Hwang, S. H., Somatilaka, B. N., Legué, E., Shimada, I. S., Familiari, N. E., Tran, V. M., Woodruff, J. B., Liem, K. F., Jr, & Mukhopadhyay, S. (2023). Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia. Molecular biology of the cell, 34(3), ar18. https://doi.org/10.1091/mbc.E22-10-0473

PMID: 36725887
Scott, E., Hodgson, K., Calle, B., Turner, H., Cheung, K., Bermudez, A., Marques, F. J. G., Pye, H., Yo, E. C., Islam, K., Oo, H. Z., McClurg, U. L., Wilson, L., Thomas, H., Frame, F. M., Orozco-Moreno, M., Bastian, K., Arredondo, H. M., Roustan, C., Gray, M. A., . . . Munkley, J. (2023). Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth. Oncogene , 10.1038/s41388-023-02604-x. Advance online publication. https://doi.org/10.1038/s41388-023-02604-x

PMID: 36730646
Bednash, J. S., Johns, F., Farkas, D., Elhance, A., Adair, J., Cress, K., Yount, J. S., Kenney, A. D., Londino, J. D., & Mallampalli, R. K. (2023). Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2. American journal of respiratory cell and molecular biology, 10.1165/rcmb.2022-0331OC. Advance online publication. https://doi.org/10.1165/rcmb.2022-0331OC

PMID: 36745901
Tillman, T. S., Chen, Q., Bondarenko, V., Coleman, J. A., Xu, Y., & Tang, P. (2023). SARS-CoV-2 Spike Protein Downregulates Cell Surface α7nAChR through a Helical Motif in the Spike Neck. ACS chemical neuroscience, 14 (4), 689-698. https://doi.org/10.1021/acschemneuro.2c00610

PMID: 36797403
Spangler, C. J., Skrajna, A., Foley, C. A., Nguyen, A., Budziszewski, G. R., Azzam, D. N., Arteaga, E. C., Simmons, H. C., Smith, C. B., Wesley, N. A., Wilkerson, E. M., McPherson, J. E., Kireev, D., James, L. I., Frye, S. V., Goldfarb, D., & McGinty, R. K. (2023). Structural basis of paralog-specific KDM2A/B nucleosome recognition. Nature chemical biology, 10.1038/s41589-023-01256-y. Advance online publication. https://doi.org/10.1038/s41589-023-01256-y

PMID: 36806912
Zapater I Morales, C., Carman, P. J., Soffar, D. B., Windner, S. E., Dominguez, R., & Baylies, M. K. (2023). Drosophila Tropomodulin is required for multiple actin-dependent processes within developing myofibers. Development (Cambridge, England) , dev.201194. Advance online publication. https://doi.org/10.1242/dev.201194

PMID: 36822463
Chen, Y., & Betenbaugh, M. J. (2023). Reconstruction of reverse transsulfuration pathway enables cysteine biosynthesis and enhances resilience to oxidative stress in Chinese Hamster Ovary cells. Metabolic engineering, 76, 204-214. Advance online publication. https://doi.org/10.1016/j.ymben.2023.02.010

PMID: 36792666
Elenbaas, J. S., Pudupakkam, U., Ashworth, K. J., Kang, C. J., Patel, V., Santana, K., Jung, I. H., Lee, P. C., Burks, K. H., Amrute, J. M., Mecham, R. P., Halabi, C. M., Aliso, A., Di Paola, J., & Stitziel, N. O. (2023). SVEP1 is an endogenous ligand for the orphan receptor PEAR1. Nature communications, 14 (1), 850. https://doi.org/10.1038/s41467-023-36486-0

PMID: 36797403
Spangler, C. J., Skrajna, A., Foley, C. A., Nguyen, A., Budziszewski, G. R., Azzam, D. N., Arteaga, E. C., Simmons, H. C., Smith, C. B., Wesley, N. A., Wilkerson, E. M., McPherson, J. E., Kireev, D., James, L. I., Frye, S. V., Goldfarb, D., & McGinty, R. K. (2023). Structural basis of paralog-specific KDM2A/B nucleosome recognition. Nature chemical biology, 10.1038/s41589-023-01256-y. Advance online publication. https://doi.org/10.1038/s41589-023-01256-y

PMID:

PMID: 36504343
Lal, D., Song, L., Brar, T., Cope, E. K., Keim, P., Williams, S., Chung, Y., Murugan, V., LaBaer, J., & Magee, D. M. (2022). Antibody responses to the host microbiome in chronic rhinosinusitis. International forum of allergy & rhinology, 10.1002/alr.23107. Advance online publication. https://doi.org/10.1002/alr.23107

PMID: 36476850
Hodson, C., van Twest, S., Dylewska, M., O'Rourke, J. J., Tan, W., Murphy, V. J., Walia, M., Abbouche, L., Nieminuszczy, J., Dunn, E., Bythell-Douglas, R., Heierhorst, J., Niedzwiedz, W., & Deans, A. J. (2022). Branchpoint translocation by fork remodelers as a general mechanism of R-loop removal. Cell reports, 41(10), 111749.

PMID: 36622343
Gartshteyn, Y., Askanase, A. D., Song, R., Bukhari, S., Dragovich, M., Adam, K., & Mor, A. (2022). SLAMF6 compartmentalization enhances T cell functions. Life science alliance, 6(2), e202201533. https://doi.org/10.26508/lsa.202201533

PMID: 36534696
Bennett, J. A., Steward, L. R., Rudolph, J., Voss, A. P., & Aydin, H. (2022). The structure of the human LACTB filament reveals the mechanisms of assembly and membrane binding. PLoS biology, 20(12), e3001899. https://doi.org/10.1371/journal.pbio.3001899

PMID: 36283413
McKenna, M. J., Adams, B. M., Chu, V., Paulo, J. A., & Shao, S. (2022). ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins. Molecular cell, 82(22), 4277?4289.e10. https://doi.org/10.1016/j.molcel.2022.09.035

PMID: 36416587
Dunham, D., Viswanathan, P., Gill, J., & Manzano, M. (2022). Expression Ratios of the Antiapoptotic BCL2 Family Members Dictate the Selective Addiction of Kaposi's Sarcoma-Associated Herpesvirus-Transformed Primary Effusion Lymphoma Cell Lines to MCL1. Journal of virology, e0136022. Advance online publication. https://doi.org/10.1128/jvi.01360-22

PMID: 36229430
Kokate, S. B., Ciuba, K., Tran, V. D., Kumari, R., Tojkander, S., Engel, U., Kogan, K., Kumar, S., & Lappalainen, P. (2022). Caldesmon controls stress fiber force-balance through dynamic cross-linking of myosin II and actin-tropomyosin filaments. Nature communications, 13(1), 6032. https://doi.org/10.1038/s41467-022-33688-w

PMID: 36245040
Park, H., Hundley, F. V., Yu, Q., Overmyer, K. A., Brademan, D. R., Serrano, L., Paulo, J. A., Paoli, J. C., Swarup, S., Coon, J. J., Gygi, S. P., & Wade Harper, J. (2022). Spatial snapshots of amyloid precursor protein intramembrane processing via early endosome

PMID: 36288700
Stomberski, C. T., Venetos, N. M., Zhou, H. L., Qian, Z., Collison, B. R., Field, S. J., Premont, R. T., & Stamler, J. S. (2022). A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis. Cell reports, 41(4), 111538. https://doi.org/10.1016/j.celrep.2022.111538

PMID: 36071159
Tan, J. X., & Finkel, T. (2022). A phosphoinositide signalling pathway mediates rapid lysosomal repair. Nature, 609(7928), 815?821. https://doi.org/10.1038/s41586-022-05164-4

PMID: 36164730
Qiu, Y., Kenana, R., Beharry, A., Wilhelm, S., Hsu, S. Y., Siu, V. M., Duennwald, M., & Heinemann, I. U. (2022). Histidine supplementation can escalate or rescue HARS deficiency in a Charcot Marie Tooth Disease model. Human molecular genetics, ddac239. Advance online publication. https://doi.org/10.1093/hmg/ddac239

PMID: 36194927
Alankarage, D., Enriquez, A., Steiner, R. D., Raggio, C., Higgins, M., Milnes, D., Humphreys, D. T., Duncan, E. L., Sparrow, D. B., Giampietro, P. F., Chapman, G., & Dunwoodie, S. L. (2022). Myhre syndrome is caused by dominant-negative dysregulation of SMAD4 and other co-factors. Differentiation; research in biological diversity, 128, 1?12. Advance online publication. https://doi.org/10.1016/j.diff.2022.09.002

PMID: 36130505
Granieri, L., Marocchi, F., Melixetian, M., Mohammadi, N., Nicoli, P., Cuomo, A., Bonaldi, T., Confalonieri, S., Pisati, F., Giardina, G., Bertalot, G., Bossi, D., & Lanfrancone, L. (2022). Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors. Cell reports, 40(12), 111396. https://doi.org/10.1016/j.celrep.2022.111396

PMID: 36108156
Bosse, K. R., Giudice, A. M., Lane, M. V., McIntyre, B., Schurch, P. M., Pascual-Pasto, G., Buongervino, S. N., Suresh, S., Fitzsimmons, A., Hyman, A., Gemino-Borromeo, M., Saggio, J., Berko, E. R., Daniels, A. A., Stundon, J., Friedrichsen, M., Liu, X., Margolis, M. L., Li, M. M., Brisson Tierno, M., ... Mosse, Y. P. (2022). Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma. Cancer discovery, CD-22-0287. Advance online publication. https://doi.org/10.1158/2159-8290.CD-22-0287

PMID: 36084911
Garg, P., & Manoj, N. (2022). Structure of an iminosugar complex of a glycoside hydrolase family 5 lichenase provides insights into the active site. Biochimie, S0300-9084(22)00226-7. Advance online publication. https://doi.org/10.1016/j.biochi.2022.09.001

PMID: 36157118
Shome, M., Song, L., Williams, S., Chung, Y., Murugan, V., Park, J. G., Faubion, W., Pasha, S. F., Leighton, J. A., LaBaer, J., & Qiu, J. (2022). Serological profiling of Crohn's disease and ulcerative colitis patients reveals anti-microbial antibody signatures. World journal of gastroenterology, 28(30), 4089-4101. https://doi.org/10.3748/wjg.v28.i30.4089

PMID: 35924596
Polsinelli, I., Salomone-Stagni, M., & Benini, S. (2022). Erwinia tasmaniensis levansucrase shows enantiomer selection for (S)-1,2,4-butanetriol. Acta crystallographica. Section F, Structural biology communications, 78(Pt 8), 289-296. https://doi.org/10.1107/S2053230X2200680X

PMID: 35867794
Martinez, B. I., Mousa, G. A., Fleck, K., MacCulloch, T., Diehnelt, C. W., Stephanopoulos, N.,& Stabenfeldt, S. E. (2022). Uncovering temporospatial sensitive TBI targeting strategies via in vivo phage display. Science advances, 8(29), eabo5047. https://doi.org/10.1126/sciadv.abo5047

PMID: 35850306
Goob, G., Adrian, J., Cossu, C., & Hauck, C. R. (2022). Phagocytosis mediated by the human granulocyte receptor CEACAM3 is limited by the receptor-type protein tyrosine phosphatase PTPRJ. The Journal of biological chemistry,102269. Advance online publication. https://doi.org/10.1016/j.jbc.2022.102269

PMID: 35853304
Wang, Y., Wang, M., Liu, Y., Tao, H., Banerjee, S., Srinivasan, S., Nemeth, E., Czaja, M. J., & He, P. (2022). Integrated regulation of stress responses, autophagy and survival by altered intracellular iron stores. Redox biology>, 55, 102407. Advance online publication. https://doi.org/10.1016/j.redox.2022.102407

PMID: 35764091
Zhou, J., Simon, J. M., Liao, C., Zhang, C., Hu, L., Zurlo, G., Liu, X., Fan, C., Hepperla, A., Jia, L., Tcheuyap, V. T., Zhong, H., Elias, R., Ye, J., Henne, W. M., Kapur, P., Nijhawan, D., Brugarolas, J., & Zhang, Q. (2022). An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma. Molecular cell, S1097-2765(22)00539-1. Advance online publication. https://doi.org/10.1016/j.molcel.2022.06.003

PMID: 35347323
Solis-Fernandez, G., Montero-Calle, A., Sanchez-Martinez, M., Pelaez-Garcia, A., Fernandez-Acenero, M. J., Pallares, P., Alonso-Navarro, M., Mendiola, M., Hendrix, J., Hardisson, D., Bartolome, R. A., Hofkens, J., Rocha, S., & Barderas, R. (2022). Arylhydrocarbon receptor-interacting protein regulates tumorigenic and metastatic properties of colorectal cancer cells driving liver metastasis. British journal of cancer, 126(11), 1604-1615. https://doi.org/10.1038/s41416-022-01762-1

PMID: 35653564
Kubori, T., Lee, J., Kim, H., Yamazaki, K., Nishikawa, M., Kitao, T., Oh, B. H., & Nagai, H. (2022). Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins. Proceedings of the National Academy of Sciences of the United States of America, 119(23), e2122872119. https://doi.org/10.1073/pnas.2122872119

PMID: 36712232
Yu, X., Guo, W. H., Lin, H., Cheng, R., Monroy, E. Y., Jin, F., Ding, L., Lu, D., Qi, X., Wang, M. C., & Wang, J. (2022). Discovery of a potent BTK and IKZF1/3 triple degrader through reversible covalent BTK PROTAC development. Current research in chemical biology, 2, 100029. https://doi.org/10.1016/j.crchbi.2022.100029

PMID: 35240128
Biswal, M., Lu, J., & Song, J. (2022). SARS-CoV-2 Nucleocapsid Protein Targets a Conserved Surface Groove of the NTF2-like Domain of G3BP1. Journal of molecular biology, 434(9), 167516. https://doi.org/10.1016/j.jmb.2022.167516

PMID: 35533300
Gaur, A., Lipponen, J., Yang, Y., Armen, R. S., & Wang, B. (2022). Mutation of Methionine to Asparagine but Not Leucine in Parathyroid Hormone Mimics the Loss of Biological Function upon Oxidation. Biochemistry, 10.1021/acs.biochem.2c00200. Advance online publication. https://doi.org/10.1021/acs.biochem.2c00200

PMID: 35610233
Mori, H., & Yachie, N. (2022). A framework to efficiently describe and share reproducible DNA materials and construction protocols. Nature communications, 13(1), 2894. https://doi.org/10.1038/s41467-022-30588-x

PMID: 35643313
Klemm, B. P., Sikkema, A. P., Hsu, A. L., Horng, J. C., Hall, T., Borgnia, M. J., & Schaaper, R. M. (2022). High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. The Journal of biological chemistry, 102073. Advance online publication. https://doi.org/10.1016/j.jbc.2022.102073

PMID: 35649350
Shome, M., Chung, Y., Chavan, R., Park, J. G., Qiu, J., & LaBaer, J. (2022). Serum autoantibodyome reveals that healthy individuals share common autoantibodies. Cell reports, 39(9), 110873. https://doi.org/10.1016/j.celrep.2022.110873

PMID: 35847493
Wang, H., Wang, Q., Cai, G., Duan, Z., Nugent, Z., Huang, J., Zheng, J., Borowsky, A. D., Li, J. J., Liu, P., Kung, H. J., Murphy, L., Chen, H. W., & Wang, J. (2022). Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance. Acta pharmaceutica Sinica. B, 12 (4), 1871-1884. https://doi.org/10.1016/j.apsb.2021.10.015

PMID: 35472072
Bristol, J. A., Brand, J., Ohashi, M., Eichelberg, M. R., Casco, A., Nelson, S. E., Hayes, M., Romero-Masters, J. C., Baiu, D. C., Gumperz, J. E., Johannsen, E. C., Dinh, H. Q., & Kenney, S. C. (2022). Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells. PLoS pathogens, 18(4), e1010453. https://doi.org/10.1371/journal.ppat.1010453

PMID: 35482127
Anderson, K. S., Erick, T. K., Chen, M., Daley, H., Campbell, M., Colson, Y., Mihm, M., Zakka, L. R., Hopper, M., Barry, W., Winer, E. P., Dranoff, G., & Overmoyer, B. (2022). The feasibility of using an autologous GM-CSF-secreting breast cancer vaccine to induce immunity in patients with stage II-III and metastatic breast cancers. Breast cancer research and treatment, 194(1), 65-78. https://doi.org/10.1007/s10549-022-06562-y

PMID: 35263599
Yiu, S., Guo, R., Zerbe, C., Weekes, M. P., & Gewurz, B. E. (2022). Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments. Cell reports, 38(10), 110411. https://doi.org/10.1016/j.celrep.2022.110411

PMID: 35256608
Vagene, A. J., Honap, T. P., Harkins, K. M., Rosenberg, M. S., Giffin, K., Cardenas-Arroyo, F., Leguizampn, L. P., Arnett, J., Buikstra, J. E., Herbig, A., Krause, J., Stone, A. C., & Bos, K. I. (2022). Geographically dispersed zoonotic tuberculosis in pre-contact South American human populations. Nature communications, 13(1), 1195. https://doi.org/10.1038/s41467-022-28562-8

PMID: 35328741
Singh, N., Zeke, A., & Remenyi, A. (2022). Systematic Discovery of FBXW7-Binding Phosphodegrons Highlights Mitogen-Activated Protein Kinases as Important Regulators of Intracellular Protein Levels. International journal of molecular sciences, 23(6), 3320. https://doi.org/10.3390/ijms23063320

PMID: 35349303
Niu, J., Holland, S. M., Ketschek, A., Collura, K. M., Hesketh, N. L., Hayashi, T., Gallo, G., & Thomas, G. M. (2022). Palmitoylation couples the kinases DLK and JNK3 to facilitate prodegenerative axon-to-soma signaling. Science signaling, 15(727), eabh2674. https://doi.org/10.1126/scisignal.abh2674

PMID: 35169238
O'Kell, A. L., Shome, M., Qiu, J., Williams, S., Chung, Y., LaBaer, J., Atkinson, M. A., & Wasserfall, C. (2022). Exploration of autoantibody responses in canine diabetes using protein arrays. Scientific reports, 12 (1), 2490. https://doi.org/10.1038/s41598-022-06599-5

PMID: 35401817
Lan, J., Wei, G., Liu, J., Yang, F., Sun, R., & Lu, H. (2022). Chemotherapy-induced adenosine A2B receptor expression mediates epigenetic regulation of pluripotency factors and promotes breast cancer stemness. Theranostics, 12(6), 2598?2612. https://doi.org/10.7150/thno.70581

PMID: 35240128
Biswal, M., Lu, J., & Song, J. (2022). SARS-CoV-2 Nucleocapsid Protein Targets a Conserved Surface Groove of the NTF2-like Domain of G3BP1. Journal of molecular biology, 434(9), 167516. Advance online publication. https://doi.org/10.1016/j.jmb.2022.167516

PMID: 35269644
Petigny, C., Dumont, A. A., Giguere, H., Collette, A., Holleran, B. J., Iftinca, M., Altier, C., Besserer-Offroy, E., Auger-Messier, M., & Leduc, R. (2022). Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation. International journal of molecular sciences, 23(5), 2502. https://doi.org/10.3390/ijms23052502

PMID: 35197475
Farshidfar, F., Rhrissorrakrai, K., Levovitz, C., Peng, C., Knight, J., Bacchiocchi, A., Su, J., Yin, M., Sznol, M., Ariyan, S., Clune, J., Olino, K., Parida, L., Nikolaus, J., Zhang, M., Zhao, S., Wang, Y., Huang, G., Wan, M., Li, X., ... Halaban, R. (2022). Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis. Nature communications, 13(1), 898. https://doi.org/10.1038/s41467-022-28566-4

PMID: 35167828
Koranne, R., Brown, K., Vandenbroek, H., & Taylor, W. R. (2022). C9ORF78 partially localizes to centromeres and plays a role in chromosome segregation. Experimental cell research, 113063. Advance online publication. https://doi.org/10.1016/j.yexcr.2022.113063

PMID: 35150746
Kwiatkowski, S., Bozko, M., Zarod, M., Witecka, A., Kocdemir, K., Jagielski, A. K., & Drozak, J. (2022). Recharacterization of the Mammalian Cytosolic Type 2 (R)-β-Hydroxybutyrate Dehydrogenase (BDH2) as 4-Oxo-L-Proline Reductase (EC 1.1.1.104). The Journal of biological chemistry, 101708. Advance online publication. https://doi.org/10.1016/j.jbc.2022.101708

PMID: 35137542
Dolan, S. K., & Matilla, M. A. (2022). Tools of the trade: plasmid repositories and standardized plasmid manipulation for molecular and synthetic biology. Microbial biotechnology, 10.1111/1751-7915.14012. Advance online publication. https://doi.org/10.1111/1751-7915.14012

PMID: 35102251
Howley, B. V., Mohanty, B., Dalton, A., Grelet, S., Karam, J., Dincman, T., & Howe, P. H. (2022). The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression. Oncogene, 10.1038/s41388-022-02199-9. Advance online publication. https://doi.org/10.1038/s41388-022-02199-9

PMID: 35112462
Sun, R., & Lim, S. O. (2022). FBXL20-mediated ubiquitination triggers the proteasomal degradation of 4-1BB. The FEBS journal, 10.1111/febs.16383. Advance online publication. https://doi.org/10.1111/febs.16383

PMID: 35091545
Shi, J. H., Ling, C., Wang, T. T., Zhang, L. N., Liu, W. W., Qin, Y., Tan, Y. H., Cui, N. P., & Ni, Z. Y. (2022). TRK-fused gene (TFG) regulates ULK1 stability via TRAF3-mediated ubiquitination and protects macrophages from LPS-induced pyroptosis. Cell death & disease, 13(1), 93. https://doi.org/10.1038/s41419-022-04539-9

PMID: 35154090
Juanes-Velasco, P., Landeira-Vinuela, A., Garcia-Vaquero, M. L., Lecrevisse, Q., Herrero, R., Ferruelo, A., Gongora, R., Corrales, F., Rivas, J. L., Lorente, J. A., Hernandez, A. P., & Fuentes, M. (2022). SARS-CoV-2 Infection Triggers Auto-Immune Response in ARDS. Frontiers in immunology, 13, 732197. https://doi.org/10.3389/fimmu.2022.732197

PMID: 35076015
Hwang, T., Parker, S. S., Hill, S. M., Grant, R. A., Ilunga, M. W., Sivaraman, V., Mouneimne, G., & Keating, A. E. (2022). Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH. eLife, 11, e70680. https://doi.org/10.7554/eLife.70680

PMID: 35063675
Daneshian, L., Renggli, I., Hanaway, R., Offermann, L. R., Schlachter, C. R., Hernandez Arriaza, R., Henry, S., Prakash, R., Wybouw, N., Dermauw, W., Shimizu, L. S., Van Leeuwen, T., Makris, T. M., Grbic, V., Grbic, M., & Chruszcz, M. (2022). Structural and functional characterization of β-cyanoalanine synthase from Tetranychus urticae. Insect biochemistry and molecular biology, 142, 103722. Advance online publication. https://doi.org/10.1016/j.ibmb.2022.103722

PMID: 35061899
Safaric, B., Chacin, E., Scherr, M. J., Rajappa, L., Gebhardt, C., Kurat, C. F., Cordes, T., & Duderstadt, K. E. (2022). The fork protection complex recruits FACT to reorganize nucleosomes during replication. Nucleic acids research, gkac005. Advance online publication. https://doi.org/10.1093/nar/gkac005

PMID: 35074482
de Rozieres, C. M., Pequeno, A., Shahabi, S., Lucas, T. M., Godula, K., Ghosh, G., & Joseph, S. (2022). PABP1 Drives the Selective Translation of Influenza A Virus mRNA. Journal of molecular biology, 434(5), 167460. Advance online publication. https://doi.org/10.1016/j.jmb.2022.167460

PMID: 35040477
Garranzo-Asensio, M., Solis-Fernandez, G., Montero-Calle, A., Garcia-Martinez, J. M., Fiuza, M. C., Pallares, P., Palacios-Garcia, N., Garcia-Jimenez, C., Guzman-Aranguez, A., & Barderas, R. (2022). Seroreactivity Against Tyrosine Phosphatase PTPRN Links Type 2 Diabetes and Colorectal Cancer and Identifies a Potential Diagnostic and Therapeutic Target. Diabetes, db201206. Advance online publication. https://doi.org/10.2337/db20-1206

PMID: 35128251
Dalwadi, U., Mannar, D., Zierhut, F., & Yip, C. K. (2022). Biochemical and Structural Characterization of Human Core Elongator and Its Subassemblies. ACS omega, 7(4), 3424-3433. https://doi.org/10.1021/acsomega.1c05719

PMID: 35027733
Han, H., Nakaoka, H. J., Hofmann, L., Zhou, J. J., Yu, C., Zeng, L., Nan, J., Seo, G., Vargas, R. E., Yang, B., Qi, R., Bardwell, L., Fishman, D. A., Cho, K., Huang, L., Luo, R., Warrior, R., & Wang, W. (2022). The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1. Nature cell biology, 24(1), 74-87. https://doi.org/10.1038/s41556-021-00813-8

PMID: 35008477
Fuentes, M., Srivastava, S., Gronenborn, A. M., & LaBaer, J. (2021). A Quantitative Systems Approach to Define Novel Effects of Tumour p53 Mutations on Binding Oncoprotein MDM2. International journal of molecular sciences, 23(1), 53. https://doi.org/10.3390/ijms23010053

PMID: 34944698
Lieb, A., Thaler, G., Fogli, B., Trovato, O., Posch, M. A., Kaserer, T., & Zangrandi, L. (2021). Functional Characterization of Spinocerebellar Ataxia Associated Dynorphin A Mutant Peptides. Biomedicines, 9(12), 1882. https://doi.org/10.3390/biomedicines9121882

PMID: 34893587
Rauner, G., Jin, D. X., Miller, D. H., Gierahn, T. M., Li, C. M., Sokol, E. S., Feng, Y. X., Mathis, R. A., Love, J. C., Gupta, P. B., & Kuperwasser, C. (2021). Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1. Nature communications, 12(1), 7116. https://doi.org/10.1038/s41467-021-27401-6

PMID: 31813797
Jia, J., Claude-Taupin, A., Gu, Y., Choi, S. W., Peters, R., Bissa, B., Mudd, M. H., Allers, L., Pallikkuth, S., Lidke, K. A., Salemi, M., Phinney, B., Mari, M., Reggiori, F., & Deretic, V. (2020). Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal. Developmental cell, 52(1), 69-87.e8. https://doi.org/10.1016/j.devcel.2019.10.025

PMID: 34862459
Nicosia, L., Boffo, F. L., Ceccacci, E., Conforti, F., Pallavicini, I., Bedin, F., Ravasio, R., Massignani, E., Somervaille, T., Minucci, S., & Bonaldi, T. (2022). Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML. Oncogene, 41(6), 878-894. https://doi.org/10.1038/s41388-021-02123-7

PMID: 34786730
Hogan, A. K., Sathyan, K. M., Willis, A. B., Khurana, S., Srivastava, S., Zasadzinska, E., Lee, A. S., Bailey, A. O., Gaynes, M. N., Huang, J., Bodner, J., Rosencrance, C. D., Wong, K. A., Morgan, M. A., Eagen, K. P., Shilatifard, A., & Foltz, D. R. (2021). UBR7 acts as a histone chaperone for post-nucleosomal histone H3. The EMBO journal, 40(24), e108307. https://doi.org/10.15252/embj.2021108307

PMID: 34788392
Coutelier, M., Jacoupy, M., Janer, A., Renaud, F., Auger, N., Saripella, G. V., Ancien, F., Pucci, F., Rooman, M., Gilis, D., Larivière, R., Sgarioto, N., Valter, R., Guillot-Noel, L., Le Ber, I., Sayah, S., Charles, P., Nümann, A., Pauly, M. G., Helmchen, C., ... Stevanin, G. (2021). NPTX1 mutations trigger endoplasmic reticulum stress and cause autosomal dominant cerebellar ataxia. Brain : a journal of neurology, awab407. Advance online publication. https://doi.org/10.1093/brain/awab407

PMID: 34764457
Schworer, S., Pavlova, N. N., Cimino, F. V., King, B., Cai, X., Sizemore, G. M., & Thompson, C. B. (2021). Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment. Nature metabolism, 3(11), 1484-1499. https://doi.org/10.1038/s42255-021-00480-x

PMID: 34728711
Kumari, R., Hummerich, H., Shen, X., Fischer, M., Litovchick, L., Mittnacht, S., DeCaprio, J. A., & Jat, P. S. (2021). Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence. Scientific reports, 11(1), 21506. https://doi.org/10.1038/s41598-021-01012-z

PMID: 34560002
Linares, J. F., Zhang, X., Martinez-Ordonez, A., Duran, A., Kinoshita, H., Kasashima, H., Nakanishi, N., Nakanishi, Y., Carelli, R., Cappelli, L., Arias, E., Yashiro, M., Ohira, M., Patel, S., Inghirami, G., Loda, M., Cuervo, A. M., Diaz-Meco, M. T., & Moscat, J. (2021). PKC λ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis. Molecular cell, 81(21), 4509-4526.e10. https://doi.org/10.1016/j.molcel.2021.08.039

PMID: 34834422
Samardzija, B., Pavesic Radonja, A., Zaharija, B., Bergman, M., Renner, E., Palkovits, M., Rubesa, G., & Bradshaw, N. J. (2021). Protein Aggregation of NPAS3, Implicated in Mental Illness, Is Not Limited to the V304I Mutation. Journal of personalized medicine, 11(11), 1070. https://doi.org/10.3390/jpm11111070

PMID: 34670092
Omenn, G. S., Lane, L., Overall, C. M., Paik, Y. K., Cristea, I. M., Corrales, F. J., Lindskog, C., Weintraub, S., Roehrl, M., Liu, S., Bandeira, N., Srivastava, S., Chen, Y. J., Aebersold, R., Moritz, R. L., & Deutsch, E. W. (2021). Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project. Journal of proteome research, 20(12), 5227-5240. https://doi.org/10.1021/acs.jproteome.1c00590

PMID: 34610008
Bhandari, B. K., Lim, C. S., Remus, D. M., Chen, A., van Dolleweerd, C., & Gardner, P. P. (2021). Analysis of 11,430 recombinant protein production experiments reveals that protein yield is tunable by synonymous codon changes of translation initiation sites. PLoS computational biology, 17(10), e1009461. https://doi.org/10.1371/journal.pcbi.1009461

PMID: 34614347
Lu, Y., Vibhute, S., Li, L., Okumu, A., Ratigan, S. C., Nolan, S., Papa, J. L., Mann, C. A., English, A., Chen, A., Seffernick, J. T., Koci, B., Duncan, L. R., Roth, B., Cummings, J. E., Slayden, R. A., Lindert, S., McElroy, C. A., Wozniak, D. J., Yalowich, J., ... Mitton-Fry, M. J. (2021). Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA. Journal of medicinal chemistry, 64(20), 15214-15249. https://doi.org/10.1021/acs.jmedchem.1c01250

PMID: 34592152
Lu, H., Lyu, Y., Tran, L., Lan, J., Xie, Y., Yang, Y., Murugan, N. L., Wang, Y. J., & Semenza, G. L. (2021). HIF-1 recruits NANOG as a coactivator for TERT gene transcription in hypoxic breast cancer stem cells. Cell reports, 36(13), 109757. https://doi.org/10.1016/j.celrep.2021.109757

PMID: 34560002
Linares, J. F., Zhang, X., Martinez-Ordonez, A., Duran, A., Kinoshita, H., Kasashima, H., Nakanishi, N., Nakanishi, Y., Carelli, R., Cappelli, L., Arias, E., Yashiro, M., Ohira, M., Patel, S., Inghirami, G., Loda, M., Cuervo, A. M., Diaz-Meco, M. T., & Moscat, J. (2021). PKC λ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis. Molecular cell, 81(21), 4509-4526.e10. https://doi.org/10.1016/j.molcel.2021.08.039

PMID: 34552088
Sharma, R., Choi, K. J., Quan, M. D., Sharma, S., Sankaran, B., Park, H., LaGrone, A., Kim, J. J., MacKenzie, K. R., Ferreon, A., Kim, C., & Ferreon, J. C. (2021). Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization. Nature communications, 12(1), 5579. https://doi.org/10.1038/s41467-021-25761-7

PMID: 34538581
Oracz, G., Zarod, M., Ewers, M., Laumen, H., Gambin, T., Kaminski, P., Grabowska, I., Drozak, A., Kwiatkowski, S., Wertheim-Tysarowska, K., Kolodziejczyk, E., Domaszewicz, A., Dorozko, B., Kosinska, J., Gluszek, S., Koziel, D., Ploski, R., Rosendahl, J., Witt, H., Drozak, J., ... Rygiel, A. M. (2021). Loss of function TRPV6 variants are associated with chronic pancreatitis in nonalcoholic early-onset Polish and German patients. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 21(8), 1434-1442. https://doi.org/10.1016/j.pan.2021.09.005

PMID: 34481949
Pauwels, E., Rutz, C., Provinciael, B., Stroobants, J., Schols, D., Hartmann, E., Krause, E., Stephanowitz, H., Schulein, R., & Vermeire, K. (2021). A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide. Molecular & cellular proteomics : MCP, 20, 100144. https://doi.org/10.1016/j.mcpro.2021.100144

PMID: 34480898
Fisher, A. L., Srole, D. N., Palaskas, N. J., Meriwether, D., Reddy, S. T., Ganz, T., & Nemeth, E. (2021). Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα -mediated apoptosis. The Journal of biological chemistry, 297(4), 101156. https://doi.org/10.1016/j.jbc.2021.101156

PMID: 34435619
Smith, C. M., Li, A., Krishnamurthy, N., & Lemmon, M. A. (2021). Phosphatidylserine binding directly regulates TIM-3 function. The Biochemical journal, 478(17), 3331-3349. https://doi.org/10.1042/BCJ20210425

PMID: 34423453
Borghesan, E., Smith, E. P., Myeni, S., Binder, K., Knodler, L. A., & Celli, J. (2021). A Brucella effector modulates the Arf6-Rab8a GTPase cascade to promote intravacuolar replication. The EMBO journal, 40(19), e107664. https://doi.org/10.15252/embj.2021107664

PMID: 34428449
Puthenveetil, R., Lun, C. M., Murphy, R. E., Healy, L. B., Vilmen, G., Christenson, E. T., Freed, E. O., & Banerjee, A. (2021). S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity. The Journal of biological chemistry, 297(4), 101112. https://doi.org/10.1016/j.jbc.2021.101112

PMID: 34408191
Santilli, R. T., Williamson, J. E., 3rd, Shibata, Y., Sowers, R. P., Fleischman, A. N., & Tan, S. (2021). The Penn State Protein Ladder system for inexpensive protein molecular weight markers. Scientific reports, 11(1), 16703. https://doi.org/10.1038/s41598-021-96051-x

PMID: 34399854
Gao, F. J., Klinedinst, D., Fernandez, F. X., Cheng, B., Savonenko, A., Devenney, B., Li, Y., Wu, D., Pomper, M. G., & Reeves, R. H. (2021). Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates. Acta neuropathologica communications, 9(1), 137. https://doi.org/10.1186/s40478-021-01237-z

PMID: 34505004
Maron, M. I., Lehman, S. M., Gayatri, S., DeAngelo, J. D., Hegde, S., Lorton, B. M., Sun, Y., Bai, D. L., Sidoli, S., Gupta, V., Marunde, M. R., Bone, J. R., Sun, Z. W., Bedford, M. T., Shabanowitz, J., Chen, H., Hunt, D. F., & Shechter, D. (2021). Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferases. iScience, 24(9), 102971. https://doi.org/10.1016/j.isci.2021.102971

PMID: 34494400
Casey, C. A., Macke, A. J., Gough, R. R., Pachikov, A. N., Morris, M. E., Thomes, P. G., Kubik, J. L., Holzapfel, M. S., & Petrosyan, A. (2022). Alcohol-Induced Liver Injury: Down-regulation and Redistribution of Rab3D Results in Atypical Protein Trafficking. Hepatology communications, 6(2), 374-388. https://doi.org/10.1002/hep4.1811

PMID: 34384782
Li, D., & Mukhopadhyay, S. (2021). A three-pocket model for substrate coordination and selectivity by the nucleotide sugar transporters SLC35A1 and SLC35A2. The Journal of biological chemistry, 297(3), 101069. https://doi.org/10.1016/j.jbc.2021.101069

PMID: 34384519
Izadifar, A., Courchet, J., Virga, D. M., Verreet, T., Hamilton, S., Ayaz, D., Misbaer, A., Vandenbogaerde, S., Monteiro, L., Petrovic, M., Sachse, S., Yan, B., Erfurth, M. L., Dascenco, D., Kise, Y., Yan, J., Edwards-Faret, G., Lewis, T., Polleux, F., & Schmucker, D. (2021). Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed. Neuron, 109(18), 2864-2883.e8. https://doi.org/10.1016/j.neuron.2021.07.006

PMID: 34439824
Vologzhannikova, A. A., Shevelyova, M. P., Kazakov, A. S., Sokolov, A. S., Borisova, N. I., Permyakov, E. A., Kircheva, N., Nikolova, V., Dudev, T., & Permyakov, S. E. (2021). Strontium Binding to α-Parvalbumin, a Canonical Calcium-Binding Protein of the "EF-Hand" Family. Biomolecules, 11(8), 1158. https://doi.org/10.3390/biom11081158

PMID: 34352913
Graffunder, A. S., Paisdzior, S., Opitz, R., Renko, K., Kuhnen, P., & Biebermann, H. (2022). Design and Characterization of a Fluorescent Reporter Enabling Live-cell Monitoring of MCT8 Expression. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 130(2), 134-140. https://doi.org/10.1055/a-1522-8535

PMID: 34436454
Yang, G. H., Fontaine, D. A., Lodh, S., Blumer, J. T., Roopra, A., & Davis, D. B. (2021). TCF19 Impacts a Network of Inflammatory and DNA Damage Response Genes in the Pancreatic β-Cell. Metabolites, 11(8), 513. https://doi.org/10.3390/metabo11080513

PMID: 34331854
Wu, H., Shajahan, A., Yang, J. Y., Capota, E., Wands, A. M., Arthur, C. M., Stowell, S. R., Moremen, K. W., Azadi, P., & Kohler, J. J. (2022). A photo-cross-linking GlcNAc analog enables covalent capture of N-linked glycoprotein-binding partners on the cell surface. Cell chemical biology, 29(1), 84-97.e8. https://doi.org/10.1016/j.chembiol.2021.07.007

PMID: 34319576
Hung, W. Y., Lee, W. J., Cheng, G. Z., Tsai, C. H., Yang, Y. C., Lai, T. C., Chen, J. Q., Chung, C. L., Chang, J. H., & Chien, M. H. (2021). Blocking MMP-12-modulated epithelial-mesenchymal transition by repurposing penfluridol restrains lung adenocarcinoma metastasis via uPA/uPAR/TGF-β/Akt pathway. Cellular oncology (Dordrecht), 44(5), 1087-1103. https://doi.org/10.1007/s13402-021-00620-1

PMID: 34330897
Laliotis, G. I., Chavdoula, E., Paraskevopoulou, M. D., Kaba, A., La Ferlita, A., Singh, S., Anastas, V., Nair, K. A., 2nd, Orlacchio, A., Taraslia, V., Vlachos, I., Capece, M., Hatzigeorgiou, A., Palmieri, D., Tsatsanis, C., Alaimo, S., Sehgal, L., Carbone, D. P., Coppola, V., & Tsichlis, P. N. (2021). AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing. Nature communications, 12(1), 4624. https://doi.org/10.1038/s41467-021-24795-1

PMID: 34315807
Liu, Q., Bautista-Gomez, J., Higgins, D. A., Yu, J., & Xiong, Y. (2021). Dysregulation of the AP2M1 phosphorylation cycle by LRRK2 impairs endocytosis and leads to dopaminergic neurodegeneration. Science signaling, 14(693), eabg3555. https://doi.org/10.1126/scisignal.abg3555

PMID: 34303155
Wan, Z., Zhang, S., Zhong, A. X., Shelton, S. E., Campisi, M., Sundararaman, S. K., Offeddu, G. S., Ko, E., Ibrahim, L., Coughlin, M. F., Liu, T., Bai, J., Barbie, D. A., & Kamm, R. D. (2021). A robust vasculogenic microfluidic model using human immortalized endothelial cells and Thy1 positive fibroblasts. Biomaterials, 276, 121032. https://doi.org/10.1016/j.biomaterials.2021.121032

PMID: 34265304
Sanderson, M. R., Fahlman, R. P., & Wevrick, R. (2021). The N-terminal domain of the Schaaf-Yang syndrome protein MAGEL2 likely has a role in RNA metabolism. The Journal of biological chemistry, 297(2), 100959. https://doi.org/10.1016/j.jbc.2021.100959

PMID: 34226627
Wang, H., Poe, A., Pak, L., Nandakumar, K., Jandu, S., Steppan, J., Loser, R., & Santhanam, L. (2021). An in situ activity assay for lysyl oxidases. Communications biology, 4(1), 840. https://doi.org/10.1038/s42003-021-02354-0

PMID: 34242503
Nagarajan, S., Qian, Z. Y., Marimuthu, P., Alkayed, N. J., Kaul, S., & Barnes, A. P. (2021). Mapping the Molecular Architecture Required for Lipid-Binding Pockets Using a Subset of Established and Orphan G-Protein Coupled Receptors. Journal of chemical information and modeling, 61(7), 3442-3452. https://doi.org/10.1021/acs.jcim.1c00335

PMID: 34185510
Zhang, Q., Dong, X., Lu, J., Song, J., & Wang, Y. (2021). Chemoproteomic Approach toward Probing the Interactomes of Perfluoroalkyl Substances. Analytical chemistry, 93(27), 9634-9639. https://doi.org/10.1021/acs.analchem.1c01948

PMID: 34161773
Shen, Y., Tang, K., Chen, D., Hong, M., Sun, F., Wang, S., Ke, Y., Wu, T., Sun, R., Qian, J., & Du, Y. (2021). Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation. Cell reports, 35(12), 109272. https://doi.org/10.1016/j.celrep.2021.109272

PMID: 34169630
Arslanhan, M. D., Rauniyar, N., Yates, J. R., 3rd, & Firat-Karalar, E. N. (2021). Aurora Kinase A proximity map reveals centriolar satellites as regulators of its ciliary function. EMBO reports, 22(8), e51902. https://doi.org/10.15252/embr.202051902

PMID: 34126284
Prabhu, S. K., Li, C., Zong, G., Zhang, R., & Wang, L. X. (2021). Comparative studies on the substrate specificity and defucosylation activity of three α-l-fucosidases using synthetic fucosylated glycopeptides and glycoproteins as substrates. Bioorganic & medicinal chemistry, 42, 116243. https://doi.org/10.1016/j.bmc.2021.116243

PMID: 34096975
Pipathsouk, A., Brunetti, R. M., Town, J. P., Graziano, B. R., Breuer, A., Pellett, P. A., Marchuk, K., Tran, N. T., Krummel, M. F., Stamou, D., & Weiner, O. D. (2021). The WAVE complex associates with sites of saddle membrane curvature. The Journal of cell biology, 220(8), e202003086. https://doi.org/10.1083/jcb.202003086

PMID: 34108442
Guo, H. H., Xiong, L., Pan, J. X., Lee, D., Liu, K., Ren, X., Wang, B., Yang, X., Cui, S., Mei, L., & Xiong, W. C. (2021). Hepcidin contributes to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss. Bone research, 9(1), 31. https://doi.org/10.1038/s41413-021-00146-0

PMID: 34119805
Meric, G., Naik, S., Hunter, A. K., Robinson, A. S., & Roberts, C. J. (2021). Challenges for design of aggregation-resistant variants of granulocyte colony-stimulating factor. Biophysical chemistry, 277, 106630. https://doi.org/10.1016/j.bpc.2021.106630

PMID: 34137443
Maverick, E. E., Leek, A. N., & Tamkun, M. M. (2021). Kv2 channel-AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking. Journal of cell science, 134(12), jcs256339. https://doi.org/10.1242/jcs.256339

PMID: 34019879
Brewster, J. L., Pachl, P., McKellar, J., Selmer, M., Squire, C. J., & Patrick, W. M. (2021). Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis. The Journal of biological chemistry, 296, 100797. https://doi.org/10.1016/j.jbc.2021.100797

PMID: 29893687
Davila, A., Liu, L., Chellappa, K., Redpath, P., Nakamaru-Ogiso, E., Paolella, L. M., Zhang, Z., Migaud, M. E., Rabinowitz, J. D., & Baur, J. A. (2018). Nicotinamide adenine dinucleotide is transported into mammalian mitochondria. eLife, 7, e33246. https://doi.org/10.7554/eLife.33246

PMID: 33976187
Yang, C. S., Jividen, K., Kamata, T., Dworak, N., Oostdyk, L., Remlein, B., Pourfarjam, Y., Kim, I. K., Du, K. P., Abbas, T., Sherman, N. E., Wotton, D., & Paschal, B. M. (2021). Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly. Nature communications, 12(1), 2705. https://doi.org/10.1038/s41467-021-23055-6

PMID: 33971243
Olson, T. L., Zhang, S., Labban, D., Kaschner, E., Aceves, M., Iyer, S., Meza-Aguilar, J. D., Zook, J. D., Chun, E., Craciunescu, F. M., Liu, W., Shi, C. X., Stewart, A. K., Hansen, D. T., Meurice, N., & Fromme, P. (2021). Protein expression and purification of G-protein coupled receptor kinase 6 (GRK6), toward structure-based drug design and discovery for multiple myeloma. Protein expression and purification, 185, 105890. https://doi.org/10.1016/j.pep.2021.105890

PMID: 33957120
Michalska, K., & Joachimiak, A. (2021). Structural genomics and the Protein Data Bank. The Journal of biological chemistry, 296, 100747. https://doi.org/10.1016/j.jbc.2021.100747

PMID: 34056395
Perez-Rodriguez, S., Wulff, T., Voldborg, B. G., Altamirano, C., Trujillo-Roldan, M. A., & Valdez-Cruz, N. A. (2021). Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Protein Production in Chinese Hamster Ovary Cells. ACS omega, 6(19), 12439-12458. https://doi.org/10.1021/acsomega.0c06030

PMID: 33938112
Yeo, H. K., Park, T. H., Kim, H. Y., Jang, H., Lee, J., Hwang, G. S., Ryu, S. E., Park, S. H., Song, H. K., Ban, H. S., Yoon, H. J., & Lee, B. I. (2021). Phospholipid transfer function of PTPIP51 at mitochondria-associated ER membranes. EMBO reports, 22(6), e51323. https://doi.org/10.15252/embr.202051323

PMID: 33938619
Sofou, K., Meier, K., Sanderson, L. E., Kaminski, D., Montoliu-Gaya, L., Samuelsson, E., Blomqvist, M., Agholme, L., Gartner, J., Mühlhausen, C., Darin, N., Barakat, T. S., Schlotawa, L., van Ham, T., Asin Cayuela, J., & Sterky, F. H. (2021). Bi-allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis-like disease. EMBO molecular medicine, 13(5), e13376. https://doi.org/10.15252/emmm.202013376

PMID: 33909030
Venkatesan, A., Geng, J., Kandarpa, M., Wijeyesakere, S. J., Bhide, A., Talpaz, M., Pogozheva, I. D., & Raghavan, M. (2021). Mechanism of mutant calreticulin-mediated activation of the thrombopoietin receptor in cancers. The Journal of cell biology, 220(7), e202009179. https://doi.org/10.1083/jcb.202009179

PMID: 33891595
Lusche, D. F., Wessels, D. J., Reis, R. J., Forrest, C. C., Thumann, A. R., & Soll, D. R. (2021). New monoclonal antibodies that recognize an unglycosylated, conserved, extracellular region of CD44 in vitro and in vivo, and can block tumorigenesis. PloS one, 16(4), e0250175. https://doi.org/10.1371/journal.pone.0250175

PMID: 33895137
Mehla, J., Liechti, G., Morgenstein, R. M., Caufield, J. H., Hosseinnia, A., Gagarinova, A., Phanse, S., Goodacre, N., Brockett, M., Sakhawalkar, N., Babu, M., Xiao, R., Montelione, G. T., Vorobiev, S., den Blaauwen, T., Hunt, J. F., & Uetz, P. (2021). ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis. The Journal of biological chemistry, 296, 100700. https://doi.org/10.1016/j.jbc.2021.100700

PMID: 33891945
Fukuda, K., Lu, F., & Qin, J. (2021). Molecular basis for Ras suppressor-1 binding to PINCH-1 in focal adhesion assembly. The Journal of biological chemistry, 296, 100685. https://doi.org/10.1016/j.jbc.2021.100685

PMID: 33936146
Doner, N. M., Seay, D., Mehling, M., Sun, S., Gidda, S. K., Schmitt, K., Braus, G. H., Ischebeck, T., Chapman, K. D., Dyer, J. M., & Mullen, R. T. (2021). Arabidopsis thaliana EARLY RESPONSIVE TO DEHYDRATION 7 Localizes to Lipid Droplets via Its Senescence Domain. Frontiers in plant science, 12, 658961. https://doi.org/10.3389/fpls.2021.658961

PMID: 33744969
Bhandari, B. K., Lim, C. S., & Gardner, P. P. (2021). TISIGNER.com: web services for improving recombinant protein production. Nucleic acids research, 49(W1), W654-W661. https://doi.org/10.1093/nar/gkab175

PMID: 33730587
Ramesh, G., Jarzembowski, L., Schwarz, Y., Poth, V., Konrad, M., Knapp, M. L., Schwar, G., Lauer, A. A., Grimm, M., Alansary, D., Bruns, D., & Niemeyer, B. A. (2021). A short isoform of STIM1 confers frequency-dependent synaptic enhancement. Cell reports, 34(11), 108844. https://doi.org/10.1016/j.celrep.2021.108844

PMID: 33723373
Yin, K., Lee, J., Liu, Z., Kim, H., Martin, D. R., Wu, D., Liu, M., & Xue, X. (2021). Mitophagy protein PINK1 suppresses colon tumor growth by metabolic reprogramming via p53 activation and reducing acetyl-CoA production. Cell death and differentiation, 28(8), 2421-2435. https://doi.org/10.1038/s41418-021-00760-9

PMID: 33731716
Bang, S., Donnelly, C. R., Luo, X., Toro-Moreno, M., Tao, X., Wang, Z., Chandra, S., Bortsov, A. V., Derbyshire, E. R., & Ji, R. R. (2021). Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice. Nature communications, 12(1), 1704. https://doi.org/10.1038/s41467-021-21940-8

PMID: 33809384
Clarke, J., Thibault, P. A., Salapa, H. E., Kim, D. E., Hutchinson, C., & Levin, M. C. (2021). Multiple Sclerosis-Associated hnRNPA1 Mutations Alter hnRNPA1 Dynamics and Influence Stress Granule Formation. International journal of molecular sciences, 22(6), 2909. https://doi.org/10.3390/ijms22062909

PMID: 33707306
Yang, W. H., Lin, C. C., Wu, J., Chao, P. Y., Chen, K., Chen, P. H., & Chi, J. T. (2021). The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2. Molecular cancer research : MCR, 19(6), 1005-1014. https://doi.org/10.1158/1541-7786.MCR-20-0534

PMID: 33705388
Lu, Y. N., Kavianpour, S., Zhang, T., Zhang, X., Nguyen, D., Thombre, R., He, L., & Wang, J. (2021). MARK2 phosphorylates eIF2α in response to proteotoxic stress. PLoS biology, 19(3), e3001096. https://doi.org/10.1371/journal.pbio.3001096

PMID: 33661412
Song, L., Song, M., Camargo, M. C., Van Duine, J., Williams, S., Chung, Y., Kim, K. M., Lissowska, J., Sivins, A., Gao, W., Karthikeyan, K., Park, J., Leja, M., Cohen, J. I., LaBaer, J., Qiu, J., & Rabkin, C. S. (2021). Identification of anti-Epstein-Barr virus (EBV) antibody signature in EBV-associated gastric carcinoma. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 24(4), 858-867. https://doi.org/10.1007/s10120-021-01170-z

PMID: 33650635
Kummari, R., Dutta, S., Patil, S., Mudrale, S. P., & Bose, K. (2021). Elucidating the role of GRIM-19 as a substrate and allosteric activator of pro-apoptotic serine protease HtrA2. The Biochemical journal, 478(6), 1241-1259. https://doi.org/10.1042/BCJ20200923

PMID: 33649598
Peng, G. E., Pessino, V., Huang, B., & von Zastrow, M. (2021). Spatial decoding of endosomal cAMP signals by a metastable cytoplasmic PKA network. Nature chemical biology, 17(5), 558-566. https://doi.org/10.1038/s41589-021-00747-0

PMID: 33651979
Weinreb, J. T., Ghazale, N., Pradhan, K., Gupta, V., Potts, K. S., Tricomi, B., Daniels, N. J., Padgett, R. A., De Oliveira, S., Verma, A., & Bowman, T. V. (2021). Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production. Developmental cell, 56(5), 627-640.e5. https://doi.org/10.1016/j.devcel.2021.02.006

PMID: 33632871
Feng, Y., Pathria, G., Heynen-Genel, S., Jackson, M., James, B., Yin, J., Scott, D. A., & Ronai, Z. A. (2021). Identification and Characterization of IMD-0354 as a Glutamine Carrier Protein Inhibitor in Melanoma. Molecular cancer therapeutics, 20(5), 816-832. https://doi.org/10.1158/1535-7163.MCT-20-0354

PMID: 33640981
Machas, M., Kurgan, G., Abed, O. A., Shapiro, A., Wang, X., & Nielsen, D. (2021). Characterizing Escherichia coli's transcriptional response to different styrene exposure modes reveals novel toxicity and tolerance insights. Journal of industrial microbiology & biotechnology, 48(1-2), kuab019. https://doi.org/10.1093/jimb/kuab019

PMID: 33635925
Bruce, J. W., Bracken, M., Evans, E., Sherer, N., & Ahlquist, P. (2021). ZBTB2 represses HIV-1 transcription and is regulated by HIV-1 Vpr and cellular DNA damage responses. PLoS pathogens, 17(2), e1009364. https://doi.org/10.1371/journal.ppat.1009364

PMID: 33626345
Wang, H., Hou, W., Perera, A., Bettler, C., Beach, J. R., Ding, X., Li, J., Denning, M. F., Dhanarajan, A., Cotler, S. J., Joyce, C., Yin, J., Ahmed, F., Roberts, L. R., & Qiu, W. (2021). Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling. Cell reports, 34(8), 108765. https://doi.org/10.1016/j.celrep.2021.108765

PMID: 33313679
Carr, H. S., Chang, J. T., & Frost, J. A. (2021). The PDZ Domain Protein SYNJ2BP Regulates GRK-Dependent Sst2A Phosphorylation and Downstream MAPK Signaling. Endocrinology, 162(2), bqaa229. https://doi.org/10.1210/endocr/bqaa229

PMID: 35150746
Kwiatkowski, S., Bozko, M., Zarod, M., Witecka, A., Kocdemir, K., Jagielski, A. K., & Drozak, J. (2022). Recharacterization of the Mammalian Cytosolic Type 2 (R)-β-Hydroxybutyrate Dehydrogenase (BDH2) as 4-Oxo-L-Proline Reductase (EC 1.1.1.104). The Journal of biological chemistry, 101708. Advance online publication. https://doi.org/10.1016/j.jbc.2022.101708

PMID: 33622117
Palazzo, A., & Marsano, R. M. (2021). Transposable elements: a jump toward the future of expression vectors. Critical reviews in biotechnology, 41(5), 792-808. https://doi.org/10.1080/07388551.2021.1888067

PMID: 33671632
Manica, G., Ghenea, S., Munteanu, C., Martin, E. C., Butnaru, C., Surleac, M., Chiritoiu, G. N., Alexandru, P. R., Petrescu, A. J., & Petrescu, S. M. (2021). EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning. International journal of molecular sciences, 22(4), 2172. https://doi.org/10.3390/ijms22042172

PMID: 33607980
Ranaghan, M. J., Li, J. J., Laprise, D. M., & Garvie, C. W. (2021). Assessing optimal: inequalities in codon optimization algorithms. BMC biology, 19(1), 36. https://doi.org/10.1186/s12915-021-00968-8

PMID: 33665624
Kirby, I. T., Sanderson, D. J., & Cohen, M. S. (2021). PASTA: PARP activity screening and inhibitor testing assay. STAR protocols, 2(1), 100344. https://doi.org/10.1016/j.xpro.2021.100344

PMID: 33669244
Kim, H. J., & Kim, J. (2021). OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase. International journal of molecular sciences, 22(4), 1936. https://doi.org/10.3390/ijms22041936

PMID: 33669337
Caster, D. J., Korte, E. A., Merchant, M. L., Klein, J. B., Barati, M. T., Joglekar, A., Wilkey, D. W., Coventry, S., Hata, J., Rovin, B. H., Harley, J. B., Namjou-Khales, B., McLeish, K. R., & Powell, D. W. (2021). Patients with Proliferative Lupus Nephritis Have Autoantibodies That React to Moesin and Demonstrate Increased Glomerular Moesin Expression. Journal of clinical medicine, 10(4), 793. https://doi.org/10.3390/jcm10040793

PMID: 33617877
Van, A. N., Kunkel, M. T., Baffi, T. R., Lordén, G., Antal, C. E., Banerjee, S., & Newton, A. C. (2021). Protein kinase C fusion proteins are paradoxically loss of function in cancer. The Journal of biological chemistry, 296, 100445. https://doi.org/10.1016/j.jbc.2021.100445

PMID: 33590412
Gao, K., Lunev, S., van den Berg, M., Al-Dahmani, Z. M., Evans, S., Mertens, D., Meurs, H., Gosens, R., & Groves, M. R. (2021). A synthetic peptide as an allosteric inhibitor of human arginase I and II. Molecular biology reports, 48(2), 1959-1966. https://doi.org/10.1007/s11033-021-06176-5

PMID: 33590815
Chirinskaite, A. V., Siniukova, V. A., Velizhanina, M. E., Sopova, J. V., Belashova, T. A., & Zadorsky, S. P. (2021). STXBP1 forms amyloid-like aggregates in rat brain and demonstrates amyloid properties in bacterial expression system. Prion, 15(1), 29-36. https://doi.org/10.1080/19336896.2021.1883980

PMID: 34862459
Nicosia, L., Boffo, F. L., Ceccacci, E., Conforti, F., Pallavicini, I., Bedin, F., Ravasio, R., Massignani, E., Somervaille, T., Minucci, S., & Bonaldi, T. (2022). Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML. Oncogene, 41(6), 878-894. https://doi.org/10.1038/s41388-021-02123-7

PMID: 34610008
Bhandari, B. K., Lim, C. S., Remus, D. M., Chen, A., van Dolleweerd, C., & Gardner, P. P. (2021). Analysis of 11,430 recombinant protein production experiments reveals that protein yield is tunable by synonymous codon changes of translation initiation sites. PLoS computational biology, 17(10), e1009461. https://doi.org/10.1371/journal.pcbi.1009461

PMID: 33565573
Mohapatra, S. B., & Manoj, N. (2021). Structural basis of catalysis and substrate recognition by the NAD(H)-dependent α-d-glucuronidase from the glycoside hydrolase family 4. The Biochemical journal, 478(4), 943-959. https://doi.org/10.1042/BCJ20200824

PMID: 33556628
Miller, C. J., McGinnis, J. E., Martinez, M. J., Wang, G., Zhou, J., Simmons, E., Amet, T., Abdeen, S. J., Van Huysse, J. W., Bowsher, R. R., & Kay, B. K. (2021). FN3-based monobodies selective for the receptor binding domain of the SARS-CoV-2 spike protein. New biotechnology, 62, 79-85. https://doi.org/10.1016/j.nbt.2021.01.010

PMID: 33547416
Li, J., Ma, X., Banerjee, S., Chen, H., Ma, W., Bode, A. M., & Dong, Z. (2021). Crystal structure of the human PRPK-TPRKB complex. Communications biology, 4(1), 167. https://doi.org/10.1038/s42003-021-01683-4

PMID: 33526784
Amalfitano, E., Karlikow, M., Norouzi, M., Jaenes, K., Cicek, S., Masum, F., Sadat Mousavi, P., Guo, Y., Tang, L., Sydor, A., Ma, D., Pearson, J. D., Trcka, D., Pinette, M., Ambagala, A., Babiuk, S., Pickering, B., Wrana, J., Bremner, R., Mazzulli, T., ... Pardee, K. (2021). A glucose meter interface for point-of-care gene circuit-based diagnostics. Nature communications, 12(1), 724. https://doi.org/10.1038/s41467-020-20639-6

PMID: 33571115
Srivastava, S., Sahu, U., Zhou, Y., Hogan, A. K., Sathyan, K. M., Bodner, J., Huang, J., Wong, K. A., Khalatyan, N., Savas, J. N., Ntziachristos, P., Ben-Sahra, I., & Foltz, D. R. (2021). NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia. Science advances, 7(5), eabc9781. https://doi.org/10.1126/sciadv.abc9781

PMID: 34625544
Hendriks, I. A., Buch-Larsen, S. C., Prokhorova, E., Elsborg, J. D., Rebak, A., Zhu, K., Ahel, D., Lukas, C., Ahel, I., & Nielsen, M. L. (2021). The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome. Nature communications, 12(1), 5893. https://doi.org/10.1038/s41467-021-26172-4

PMID: 33473118
Elsayed, A. K., Younis, I., Ali, G., Hussain, K., & Abdelalim, E. M. (2021). Aberrant development of pancreatic beta cells derived from human iPSCs with FOXA2 deficiency. Cell death & disease, 12(1), 103. https://doi.org/10.1038/s41419-021-03390-8

PMID: 34962968
Ivanov, S. S., Castore, R., Juarez Rodriguez, M. D., Circu, M., & Dragoi, A. M. (2021). Neisseria gonorrhoeae subverts formin-dependent actin polymerization to colonize human macrophages. PLoS pathogens, 17(12), e1010184. https://doi.org/10.1371/journal.ppat.1010184

PMID: 34713805
Trofimenko, E., Grasso, G., Heulot, M., Chevalier, N., Deriu, M. A., Dubuis, G., Arribat, Y., Serulla, M., Michel, S., Vantomme, G., Ory, F., Dam, L. C., Puyal, J., Amati, F., Lüthi, A., Danani, A., & Widmann, C. (2021). Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore. eLife, 10, e69832. https://doi.org/10.7554/eLife.69832

PMID: 33465001
Van de Sande, D. V., Kopljar, I., Maaike, A., Teisman, A., Gallacher, D. J., Bart, L., Snyders, D. J., Leybaert, L., Lu, H. R., & Labro, A. J. (2021). The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cells. Channels (Austin, Tex.), 15(1), 239-252. https://doi.org/10.1080/19336950.2021.1871815

PMID: 34399854
Gao, F. J., Klinedinst, D., Fernandez, F. X., Cheng, B., Savonenko, A., Devenney, B., Li, Y., Wu, D., Pomper, M. G., & Reeves, R. H. (2021). Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates. Acta neuropathologica communications, 9(1), 137. https://doi.org/10.1186/s40478-021-01237-z

PMID: 33397718
Hammond, R. G., Schormann, N., McPherson, R. L., Leung, A., Deivanayagam, C., & Johnson, M. A. (2021). ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4. Proceedings of the National Academy of Sciences of the United States of America, 118(2), e2004500118. https://doi.org/10.1073/pnas.2004500118

PMID: 33317513
Brookhouser, N., Nguyen, T., Tekel, S. J., Standage-Beier, K., Wang, X., & Brafman, D. A. (2020). A Cas9-mediated adenosine transient reporter enables enrichment of ABE-targeted cells. BMC biology, 18(1), 193. https://doi.org/10.1186/s12915-020-00929-7

PMID: 33094812
Ahmed, F., Paul, M. D., & Hristova, K. (2020). The biophysical basis of receptor tyrosine kinase ligand functional selectivity: Trk-B case study. The Biochemical journal, 477(23), 4515-4526. https://doi.org/10.1042/BCJ20200671

PMID: 33290741
Velazquez, J. J., LeGraw, R., Moghadam, F., Tan, Y., Kilbourne, J., Maggiore, J. C., Hislop, J., Liu, S., Cats, D., Chuva de Sousa Lopes, S. M., Plaisier, C., Cahan, P., Kiani, S., & Ebrahimkhani, M. R. (2021). Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids. Cell systems, 12(1), 41-55.e11. https://doi.org/10.1016/j.cels.2020.11.002

PMID: 33277614
Jenkins, M. L., Harris, N. J., Dalwadi, U., Fleming, K. D., Ziemianowicz, D. S., Rafiei, A., Martin, E. M., Schriemer, D. C., Yip, C. K., & Burke, J. E. (2020). The substrate specificity of the human TRAPPII complex's Rab-guanine nucleotide exchange factor activity. Communications biology, 3(1), 735. https://doi.org/10.1038/s42003-020-01459-2

PMID: 33275876
Hou, C., Mandal, A., Rohr, J., & Tsodikov, O. V. (2021). Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure (London, England : 1993), 29(5), 404-412.e4. https://doi.org/10.1016/j.str.2020.11.012

PMID: 33257861
Ng, A., Khoshakhlagh, P., Rojo Arias, J. E., Pasquini, G., Wang, K., Swiersy, A., Shipman, S. L., Appleton, E., Kiaee, K., Kohman, R. E., Vernet, A., Dysart, M., Leeper, K., Saylor, W., Huang, J. Y., Graveline, A., Taipale, J., Hill, D. E., Vidal, M., Melero-Martin, J. M., ... Church, G. M. (2021). A comprehensive library of human transcription factors for cell fate engineering. Nature biotechnology, 39(4), 510-519. https://doi.org/10.1038/s41587-020-0742-6

PMID: 33264619
Wohlhieter, C. A., Richards, A. L., Uddin, F., Hulton, C. H., Quintanal-Villalonga, A., Martin, A., de Stanchina, E., Bhanot, U., Asher, M., Shah, N. S., Hayatt, O., Buonocore, D. J., Rekhtman, N., Shen, R., Arbour, K. C., Donoghue, M., Poirier, J. T., Sen, T., & Rudin, C. M. (2020). Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer. Cell reports, 33(9), 108444. https://doi.org/10.1016/j.celrep.2020.108444

PMID: 33124765
Touma, A. M., Malik, R. U., Gupte, T., & Sivaramakrishnan, S. (2020). Allosteric modulation of adenosine A1 and cannabinoid 1 receptor signaling by G-peptides. Pharmacology research & perspectives, 8(6), e00673. https://doi.org/10.1002/prp2.673

PMID: 33253913
Bednash, J. S., Johns, F., Patel, N., Smail, T. R., Londino, J. D., & Mallampalli, R. K. (2021). The deubiquitinase STAMBP modulates cytokine secretion through the NLRP3 inflammasome. Cellular signalling, 79, 109859. https://doi.org/10.1016/j.cellsig.2020.109859

PMID: 33257573
Aras, S., Purandare, N., Gladyck, S., Somayajulu-Nitu, M., Zhang, K., Wallace, D. C., & Grossman, L. I. (2020). Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms. Proceedings of the National Academy of Sciences of the United States of America, 117(50), 32056-32065. https://doi.org/10.1073/pnas.2005877117

PMID: 33229547
Yi, J., Zhu, J., Wu, J., Thompson, C. B., & Jiang, X. (2020). Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis. Proceedings of the National Academy of Sciences of the United States of America, 117(49), 31189-31197. https://doi.org/10.1073/pnas.2017152117

PMID: 33434574
Li, J., Ma, X., Banerjee, S., Baruah, S., Schnicker, N. J., Roh, E., Ma, W., Liu, K., Bode, A. M., & Dong, Z. (2021). Structural basis for multifunctional roles of human Ints3 C-terminal domain. The Journal of biological chemistry, 296, 100112. https://doi.org/10.1074/jbc.RA120.016393

PMID: 33207226
Kasashima, H., Duran, A., Martinez-Ordonez, A., Nakanishi, Y., Kinoshita, H., Linares, J. F., Reina-Campos, M., Kudo, Y., L'Hermitte, A., Yashiro, M., Ohira, M., Bao, F., Tauriello, D., Batlle, E., Diaz-Meco, M. T., & Moscat, J. (2021). Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population. Developmental cell, 56(1), 95-110.e10. https://doi.org/10.1016/j.devcel.2020.10.014

PMID: 33207694
Conn, V. M., Gabryelska, M., Marri, S., Stringer, B. W., Ormsby, R. J., Penn, T., Poonnoose, S., Kichenadasse, G., & Conn, S. J. (2020). SRRM4 Expands the Repertoire of Circular RNAs by Regulating Microexon Inclusion. Cells, 9(11), 2488. https://doi.org/10.3390/cells9112488

PMID: 33175491
Hou, C., McCown, C., Ivanov, D. N., & Tsodikov, O. V. (2020). Structural Insight into the DNA Binding Function of Transcription Factor ERF. Biochemistry, 10.1021/acs.biochem.0c00774. Advance online publication. https://doi.org/10.1021/acs.biochem.0c00774

PMID: 33173051
Lee, I. G., Cason, S. E., Alqassim, S. S., Holzbaur, E., & Dominguez, R. (2020). A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner. Nature communications, 11(1), 5695. https://doi.org/10.1038/s41467-020-19538-7

PMID: 33168709
Yu, X., Zhao, Q., Li, X., Chen, Y., Tian, Y., Liu, S., Xiong, W., & Huang, P. (2020). Deafness mutation D572N of TMC1 destabilizes TMC1 expression by disrupting LHFPL5 binding. Proceedings of the National Academy of Sciences of the United States of America, 117(47), 29894-29903. https://doi.org/10.1073/pnas.2011147117

PMID: 33156996
Deol, K. K., Crowe, S. O., Du, J., Bisbee, H. A., Guenette, R. G., & Strieter, E. R. (2020). Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation. Molecular cell, 80(5), 796-809.e9. https://doi.org/10.1016/j.molcel.2020.10.017

PMID: 33292665
Zhang, K., Li, H., Xin, Z., Li, Y., Wang, X., Hu, Y., Liu, H., & Cai, D. (2020). Time-restricted feeding downregulates cholesterol biosynthesis program via RORγ-mediated chromatin modification in porcine liver organoids. Journal of animal science and biotechnology, 11(1), 106. https://doi.org/10.1186/s40104-020-00511-9

PMID: 32996252
Huang, M. S., Chang, J. H., Lin, W. C., Cheng, Y. H., Li, F. A., Suen, C. S., Hwang, M. J., Chang, C. K., & Mou, K. Y. (2020). SLC38A2 Overexpression Induces a Cancer-like Metabolic Profile and Cooperates with SLC1A5 in Pan-cancer Prognosis. Chemistry, an Asian journal, 15(22), 3861-3872. https://doi.org/10.1002/asia.202001056

PMID: 33096938
Boonen, A., Singh, A. K., Hout, A. V., Das, K., Loy, T. V., Noppen, S., & Schols, D. (2020). Development of a Novel SPR Assay to Study CXCR4-Ligand Interactions. Biosensors, 10(10), 150. https://doi.org/10.3390/bios10100150

PMID: 33127913
Lee, K. M., Guerrero-Zotano, A. L., Servetto, A., Sudhan, D. R., Lin, C. C., Formisano, L., Jansen, V. M., González-Ericsson, P., Sanders, M. E., Stricker, T. P., Raj, G., Dean, K. M., Fiolka, R., Cantley, L. C., Hanker, A. B., & Arteaga, C. L. (2020). Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer. Nature communications, 11(1), 5488. https://doi.org/10.1038/s41467-020-19291-x

PMID: 33097091
Vaughan, R. M., Kupai, A., Foley, C. A., Sagum, C. A., Tibben, B. M., Eden, H. E., Tiedemann, R. L., Berryhill, C. A., Patel, V., Shaw, K. M., Krajewski, K., Strahl, B. D., Bedford, M. T., Frye, S. V., Dickson, B. M., & Rothbart, S. B. (2020). The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells. Epigenetics & chromatin, 13(1), 44. https://doi.org/10.1186/s13072-020-00366-4

PMID: 33074652
Lopez Davila, A. J., Zhu, L., Fritz, L., Kraft, T., & Chalovich, J. M. (2020). The Positively Charged C-Terminal Region of Human Skeletal Troponin T Retards Activation and Decreases Calcium Sensitivity. Biochemistry, 59(43), 4189-4201. https://doi.org/10.1021/acs.biochem.0c00499

PMID: 33025105
Liu, C. H., Chang, J. H., Chang, Y. C., & Mou, K. Y. (2020). Treatment of murine colitis by Saccharomyces boulardii secreting atrial natriuretic peptide. Journal of molecular medicine (Berlin, Germany), 98(12), 1675-1687. https://doi.org/10.1007/s00109-020-01987-8

PMID: 33020179
Oba, T., Saito, T., Asada, A., Shimizu, S., Iijima, K. M., & Ando, K. (2020). Microtubule affinity-regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration. The Journal of biological chemistry, 295(50), 17138-17147. https://doi.org/10.1074/jbc.RA120.014420

PMID: 33027662
Narayan, P., Sienski, G., Bonner, J. M., Lin, Y. T., Seo, J., Baru, V., Haque, A., Milo, B., Akay, L. A., Graziosi, A., Freyzon, Y., Landgraf, D., Hesse, W. R., Valastyan, J., Barrasa, M. I., Tsai, L. H., & Lindquist, S. (2020). PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4. Cell reports, 33(1), 108224. https://doi.org/10.1016/j.celrep.2020.108224

PMID: 32968275
Xu, T. H., Liu, M., Zhou, X. E., Liang, G., Zhao, G., Xu, H. E., Melcher, K., & Jones, P. A. (2020). Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B. Nature, 586(7827), 151-155. https://doi.org/10.1038/s41586-020-2747-1

PMID: 32697405
Vetter, C. J., Thorn, D. C., Wheeler, S. G., Mundorff, C. C., Halverson, K. A., Wales, T. E., Shinde, U. P., Engen, J. R., David, L. L., Carver, J. A., & Lampi, K. J. (2020). Cumulative deamidations of the major lens protein γS-crystallin increase its aggregation during unfolding and oxidation. Protein science : a publication of the Protein Society, 29(9), 1945-1963. https://doi.org/10.1002/pro.3915

PMID: 32958558
Collura, K. M., Niu, J., Sanders, S. S., Montersino, A., Holland, S. M., & Thomas, G. M. (2020). The palmitoyl acyltransferases ZDHHC5 and ZDHHC8 are uniquely present in DRG axons and control retrograde signaling via the Gp130/JAK/STAT3 pathway. The Journal of biological chemistry, 295(46), 15427-15437. https://doi.org/10.1074/jbc.RA120.013815

PMID: 32330446
Kwon, J. B., Vankara, A., Ettyreddy, A. R., Bohning, J. D., & Gersbach, C. A. (2020). Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators. Stem cell reports, 14(5), 755-769. https://doi.org/10.1016/j.stemcr.2020.03.026

PMID: 32913330
Prendergast, L., McClurg, U. L., Hristova, R., Berlinguer-Palmini, R., Greener, S., Veitch, K., Hernandez, I., Pasero, P., Rico, D., Higgins, J., Gospodinov, A., & Papamichos-Chronakis, M. (2020). Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability. Nature communications, 11(1), 4534. https://doi.org/10.1038/s41467-020-18306-x

PMID: 32857986
Dickson, P., Simanski, S., Ngundu, J. M., & Kodadek, T. (2020). Mechanistic Studies of the Multiple Myeloma and Melanoma Cell-Selective Toxicity of the Rpn13-Binding Peptoid KDT-11. Cell chemical biology, 27(11), 1383-1395.e5. https://doi.org/10.1016/j.chembiol.2020.08.008

PMID: 32859943
Shendy, N., Raghu, D., Roy, S., Perry, C. H., Safi, A., Branco, M. R., Homayouni, R., & Abell, A. N. (2020). Coordinated regulation of Rel expression by MAP3K4, CBP, and HDAC6 controls phenotypic switching. Communications biology, 3(1), 475. https://doi.org/10.1038/s42003-020-01200-z

PMID: 32853774
Mohapatra, S. B., & Manoj, N. (2021). A conserved π-helix plays a key role in thermoadaptation of catalysis in the glycoside hydrolase family 4. Biochimica et biophysica acta Proteins and proteomics, 1869(1), 140523. https://doi.org/10.1016/j.bbapap.2020.140523

PMID: 32835442
Chen, T., Tsang, J., Su, X. C., Li, P., Sun, W. Q., Wong, I., Choy, K. Y., Yang, Q., Tse, G., Chan, T. H., & Chow, L. (2020). SALL4 promotes tumor progression in breast cancer by targeting EMT. Molecular carcinogenesis, 59(10), 1209-1226. https://doi.org/10.1002/mc.23250

PMID: 32858261
Moparthi, L., & Koch, S. (2020). A uniform expression library for the exploration of FOX transcription factor biology. Differentiation; research in biological diversity, 115, 30-36. https://doi.org/10.1016/j.diff.2020.08.002

PMID: 32807991
Luo, E. C., Nathanson, J. L., Tan, F. E., Schwartz, J. L., Schmok, J. C., Shankar, A., Markmiller, S., Yee, B. A., Sathe, S., Pratt, G. A., Scaletta, D. B., Ha, Y., Hill, D. E., Aigner, S., & Yeo, G. W. (2020). Large-scale tethered function assays identify factors that regulate mRNA stability and translation. Nature structural & molecular biology, 27(10), 989-1000. https://doi.org/10.1038/s41594-020-0477-6

PMID: 32974937
Yang, Y., Liu, X. R., Greenberg, Z. J., Zhou, F., He, P., Fan, L., Liu, S., Shen, G., Egawa, T., Gross, M. L., Schuettpelz, L. G., & Li, W. (2020). Open conformation of tetraspanins shapes interaction partner networks on cell membranes. The EMBO journal, 39(18), e105246. https://doi.org/10.15252/embj.2020105246

PMID: 32841759
Polakowski, N., Pearce, M., Kuguyo, O., Boateng, G., Hoang, K., & Lemasson, I. (2020). The splice 1 variant of HTLV-1 bZIP factor stabilizes c-Jun. Virology, 549, 51-58. https://doi.org/10.1016/j.virol.2020.07.013

PMID: 32770037
Tang, Y., Saul, J., Nagaratnam, N., Martin-Garcia, J. M., Fromme, P., Qiu, J., & LaBaer, J. (2020). Construction of gateway-compatible baculovirus expression vectors for high-throughput protein expression and in vivo microcrystal screening. Scientific reports, 10(1), 13323. https://doi.org/10.1038/s41598-020-70163-2

PMID: 32762776
Kosti, A., de Araujo, P. R., Li, W. Q., Guardia, G., Chiou, J., Yi, C., Ray, D., Meliso, F., Li, Y. M., Delambre, T., Qiao, M., Burns, S. S., Lorbeer, F. K., Georgi, F., Flosbach, M., Klinnert, S., Jenseit, A., Lei, X., Sandoval, C. R., Ha, K., ... Penalva, L. (2020). The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation. Genome biology, 21(1), 195. https://doi.org/10.1186/s13059-020-02115-y

PMID: 32687490
Ryu, S. W., Stewart, R., Pectol, D. C., Ender, N. A., Wimalarathne, O., Lee, J. H., Zanini, C. P., Harvey, A., Huibregtse, J. M., Mueller, P., & Paull, T. T. (2020). Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells. PLoS biology, 18(7), e3000606. https://doi.org/10.1371/journal.pbio.3000606

PMID: 32661195
Duan, H. D., Mohamed-Raseek, N., & Miller, A. F. (2020). Spectroscopic evidence for direct flavin-flavin contact in a bifurcating electron transfer flavoprotein. The Journal of biological chemistry, 295(36), 12618-12634. https://doi.org/10.1074/jbc.RA120.013174

PMID: 32652011
Maiti, P., Antonicka, H., Gingras, A. C., Shoubridge, E. A., & Barrientos, A. (2020). Human GTPBP5 (MTG2) fuels mitoribosome large subunit maturation by facilitating 16S rRNA methylation. Nucleic acids research, 48(14), 7924-7943. https://doi.org/10.1093/nar/gkaa592

PMID: 32923835
Abbey, D., Elwyn, S., Hand, N. J., Musunuru, K., & Rader, D. J. (2020). Self-Organizing Human Induced Pluripotent Stem Cell Hepatocyte 3D Organoids Inform the Biology of the Pleiotropic TRIB1 Gene. Hepatology communications, 4(9), 1316-1331. https://doi.org/10.1002/hep4.1538

PMID: 32629176
Ding, Z., Kloss, J. M., Tuncali, S., Tran, N. L., & Loftus, J. C. (2020). TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance. Neoplasia (New York, N.Y.), 22(9), 352-364. https://doi.org/10.1016/j.neo.2020.06.005

PMID: 32393599
Zhou, Y., Feng, Z., Cao, F., Liu, X., Xia, X., & Yu, C. H. (2020). Abl-mediated PI3K activation regulates macrophage podosome formation. Journal of cell science, 133(11), jcs234385. https://doi.org/10.1242/jcs.234385

PMID: 34188037
Hang, Q., Zeng, L., Wang, L., Nie, L., Yao, F., Teng, H., Deng, Y., Yap, S., Sun, Y., Frank, S. J., Chen, J., & Ma, L. (2021). Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance. Nature communications, 12(1), 4033. https://doi.org/10.1038/s41467-021-24298-z

PMID: 32515734
Gibbs, Z. A., Reza, L. C., Cheng, C. C., Westcott, J. M., McGlynn, K., & Whitehurst, A. W. (2020). The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer. eLife, 9, e57679. https://doi.org/10.7554/eLife.57679

PMID: 32371395
Yin, Y., Frank, D., Zhou, W., Kaur, N., French, J. B., & Carpino, N. (2020). An unexpected 2-histidine phosphoesterase activity of suppressor of T-cell receptor signaling protein 1 contributes to the suppression of cell signaling. The Journal of biological chemistry, 295(25), 8514-8523. https://doi.org/10.1074/jbc.RA120.013482

PMID: 32499524
Mugat, B., Nicot, S., Varela-Chavez, C., Jourdan, C., Sato, K., Basyuk, E., Juge, F., Siomi, M. C., Pelisson, A., & Chambeyron, S. (2020). The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation. Nature communications, 11(1), 2818. https://doi.org/10.1038/s41467-020-16635-5

PMID: 32330456
Gillespie, M. A., Palii, C. G., Sanchez-Taltavull, D., Shannon, P., Longabaugh, W., Downes, D. J., Sivaraman, K., Espinoza, H. M., Hughes, J. R., Price, N. D., Perkins, T. J., Ranish, J. A., & Brand, M. (2020). Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis. Molecular cell, 78(5), 960-974.e11. https://doi.org/10.1016/j.molcel.2020.03.031

PMID: 32505352
Bostwick, A. M., Moya, G. E., Senti, M. L., Basu, U., Shen, J., Patel, S. S., & Dittenhafer-Reed, K. E. (2020). Phosphorylation of mitochondrial transcription factor B2 controls mitochondrial DNA binding and transcription. Biochemical and biophysical research communications, 528(3), 580-585. https://doi.org/10.1016/j.bbrc.2020.05.141

PMID: 31357902
Dogbevia, G., Grasshoff, H., Othman, A., Penno, A., & Schwaninger, M. (2020). Brain endothelial specific gene therapy improves experimental Sandhoff disease. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 40(6), 1338-1350. https://doi.org/10.1177/0271678X19865917

PMID: 32343993
Athar, Y. M., & Joseph, S. (2020). RNA-Binding Specificity of the Human Fragile X Mental Retardation Protein. Journal of molecular biology, 432(13), 3851-3868. https://doi.org/10.1016/j.jmb.2020.04.021

PMID: 32504780
Sandigursky, S., Philips, M. R., & Mor, A. (2020). SAP interacts with CD28 to inhibit PD-1 signaling in T lymphocytes. Clinical immunology (Orlando, Fla.), 217, 108485. https://doi.org/10.1016/j.clim.2020.108485

PMID: 32510469
Nagaratnam, N., Tang, Y., Botha, S., Saul, J., Li, C., Hu, H., Zaare, S., Hunter, M., Lowry, D., Weierstall, U., Zatsepin, N., Spence, J., Qiu, J., LaBaer, J., Fromme, P., & Martin-Garcia, J. M. (2020). Enhanced X-ray diffraction of in vivo-grown μNS crystals by viscous jets at XFELs. Acta crystallographica. Section F, Structural biology communications, 76(Pt 6), 278-289. https://doi.org/10.1107/S2053230X20006172

PMID: 32539762
Gu, X., Wang, B., Zhu, H., Zhou, Y., Horning, A. M., Huang, T. H., Chen, Y., Houghton, P., Lai, Z., Michalek, J. E., & Sun, L. Z. (2020). Age-associated genes in human mammary gland drive human breast cancer progression. Breast cancer research : BCR, 22(1), 64. https://doi.org/10.1186/s13058-020-01299-2

PMID: 32533638
Matti, C., D'Uonnolo, G., Artinger, M., Melgrati, S., Salnikov, A., Thelen, S., Purvanov, V., Strobel, T. D., Spannagel, L., Thelen, M., & Legler, D. F. (2020). CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4. Journal of leukocyte biology, 107(6), 1137-1154. https://doi.org/10.1002/JLB.2MA0420-295RRR

PMID: 32586379
Collins, M., Li, Y., & Bowser, R. (2020). RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases. Acta neuropathologica communications, 8(1), 91. https://doi.org/10.1186/s40478-020-00965-y

PMID: 32358557
Calabrese, A. N., Schiffrin, B., Watson, M., Karamanos, T. K., Walko, M., Humes, J. R., Horne, J. E., White, P., Wilson, A. J., Kalli, A. C., Tuma, R., Ashcroft, A. E., Brockwell, D. J., & Radford, S. E. (2020). Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients. Nature communications, 11(1), 2155. https://doi.org/10.1038/s41467-020-15702-1

PMID: 32295846
Sapkota, H., Wren, J. D., & Gorbsky, G. J. (2020). CSAG1 maintains the integrity of the mitotic centrosome in cells with defective p53. Journal of cell science, 133(10), jcs239723. https://doi.org/10.1242/jcs.239723

PMID: 32165494
Huang, W., Ray, P., Ji, W., Wang, Z., Nancarrow, D., Chen, G., Galban, S., Lawrence, T. S., Beer, D. G., Rehemtulla, A., Ramnath, N., & Ray, D. (2020). The cytochrome P450 enzyme CYP24A1 increases proliferation of mutant KRAS-dependent lung adenocarcinoma independent of its catalytic activity. The Journal of biological chemistry, 295(18), 5906-5917. https://doi.org/10.1074/jbc.RA119.011869

PMID: 32229723
Hwang, I., Pan, H., Yao, J., Elemento, O., Zheng, H., & Paik, J. (2020). CIC is a critical regulator of neuronal differentiation. JCI insight, 5(9), e135826. https://doi.org/10.1172/jci.insight.135826

PMID: 32478746
Dutoit, R., Brandt, N., Van Elder, D., & Droogmans, L. (2020). X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050. Journal of visualized experiments : JoVE, (159), 10.3791/61288. https://doi.org/10.3791/61288

PMID: 32315601
Guo, R., Jiang, C., Zhang, Y., Govande, A., Trudeau, S. J., Chen, F., Fry, C. J., Puri, R., Wolinsky, E., Schineller, M., Frost, T. C., Gebre, M., Zhao, B., Giulino-Roth, L., Doench, J. G., Teng, M., & Gewurz, B. E. (2020). MYC Controls the Epstein-Barr Virus Lytic Switch. Molecular cell, 78(4), 653-669.e8. https://doi.org/10.1016/j.molcel.2020.03.025

PMID: 31883395
Al-Zeheimi, N., & Adham, S. A. (2020). Modeling Neoadjuvant chemotherapy resistance in vitro increased NRP-1 and HER2 expression and converted MCF7 breast cancer subtype. British journal of pharmacology, 177(9), 2024-2041. https://doi.org/10.1111/bph.14966

PMID: 32132673
Ramat, A., Garcia-Silva, M. R., Jahan, C., Naït-Saïdi, R., Dufourt, J., Garret, C., Chartier, A., Cremaschi, J., Patel, V., Decourcelle, M., Bastide, A., Juge, F., & Simonelig, M. (2020). The PIWI protein Aubergine recruits eIF3 to activate translation in the germ plasm. Cell research, 30(5), 421-435. https://doi.org/10.1038/s41422-020-0294-9

PMID: 32451434
Zhang, J., & Peng, C. A. (2020). Diminution of Phagocytosed Micro/Nanoparticles by Tethering with Immunoregulatory CD200 Protein. Scientific reports, 10(1), 8604. https://doi.org/10.1038/s41598-020-65559-z

PMID: 32456285
Jiang, B., Adams, Z., Moonah, S., Shi, H., Maupin-Furlow, J., & Moskovitz, J. (2020). The Antioxidant Enzyme Methionine Sulfoxide Reductase A (MsrA) Interacts with Jab1/CSN5 and Regulates Its Function. Antioxidants (Basel, Switzerland), 9(5), 452. https://doi.org/10.3390/antiox9050452

PMID: 32496218
Rowland, R. J., Wu, L., Liu, F., & Davies, G. J. (2020). A baculoviral system for the production of human β-glucocerebrosidase enables atomic resolution analysis. Acta crystallographica . Section D, Structural biology, 76(Pt 6), 565-580. https://doi.org/10.1107/S205979832000501X

PMID: 32299194
Lee, Y. J., Lee, E. Y., Choi, B. H., Jang, H., Myung, J. K., & You, H. J. (2020). The Role of Nuclear Receptor Subfamily 1 Group H Member 4 (NR1H4) in Colon Cancer Cell Survival through the Regulation of c-Myc Stability. Molecules and cells, 43(5), 459-468. https://doi.org/10.14348/molcells.2020.0041

PMID: 32433964
Nakatake, Y., Ko, S., Sharov, A. A., Wakabayashi, S., Murakami, M., Sakota, M., Chikazawa, N., Ookura, C., Sato, S., Ito, N., Ishikawa-Hirayama, M., Mak, S. S., Jakt, L. M., Ueno, T., Hiratsuka, K., Matsushita, M., Goparaju, S. K., Akiyama, T., Ishiguro, K. I., Oda, M., ? Ko, M. (2020). Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors. Cell reports, 31(7), 107655. https://doi.org/10.1016/j.celrep.2020.107655

PMID: 32455562
Barba-Vicente, V., Parra, M., Boyero-Benito, J. F., Auría-Soro, C., Juanes-Velasco, P., Landeira-Viñuela, A., Furones-Cuadrado, Á., Hernández, Á. P., Manzano-Román, R., & Fuentes, M. (2020). Detection of Human p53 In-Vitro Expressed in a Transcription-Translation Cell-Free System by a Novel Conjugate Based on Cadmium Sulphide Nanoparticles. Nanomaterials (Basel, Switzerland), 10(5), 984. https://doi.org/10.3390/nano10050984

PMID: 32330423
Bararia, D., Hildebrand, J. A., Stolz, S., Haebe, S., Alig, S., Trevisani, C. P., Osorio-Barrios, F., Bartoschek, M. D., Mentz, M., Pastore, A., Gaitzsch, E., Heide, M., Jurinovic, V., Rautter, K., Gunawardana, J., Sabdia, M. B., Szczepanowski, M., Richter, J., Klapper, W., Louissaint, A., Jr, ? Weigert, O. (2020). Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma. Cell reports, 31(5), 107522. https://doi.org/10.1016/j.celrep.2020.107522

PMID: 32343993
Athar, Y. M., & Joseph, S. (2020). RNA-Binding Specificity of the Human Fragile X Mental Retardation Protein. Journal of molecular biology, 432(13), 3851-3868. https://doi.org/10.1016/j.jmb.2020.04.021

PMID: 32330446
Kwon, J. B., Vankara, A., Ettyreddy, A. R., Bohning, J. D., & Gersbach, C. A. (2020). Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators. Stem cell reports, 14(5), 755-769. https://doi.org/10.1016/j.stemcr.2020.03.026

PMID: 32315618
Leonard, D., Huang, W., Izadmehr, S., O'Connor, C. M., Wiredja, D. D., Wang, Z., Zaware, N., Chen, Y., Schlatzer, D. M., Kiselar, J., Vasireddi, N., Schüchner, S., Perl, A. L., Galsky, M. D., Xu, W., Brautigan, D. L., Ogris, E., Taylor, D. J., & Narla, G. (2020). Selective PP2A Enhancement through Biased Heterotrimer Stabilization. Cell, 181(3), 688-701.e16. https://doi.org/10.1016/j.cell.2020.03.038

PMID: 32255429
Harman, J. L., Loes, A. N., Warren, G. D., Heaphy, M. C., Lampi, K. J., & Harms, M. J. (2020). Evolution of multifunctionality through a pleiotropic substitution in the innate immune protein S100A9. eLife, 9, e54100. https://doi.org/10.7554/eLife.54100

PMID: 32300005
Garcia, V., Park, E. J., Siragusa, M., Frohlich, F., Mahfuzul Haque, M., Pascale, J. V., Heberlein, K. R., Isakson, B. E., Stuehr, D. J., & Sessa, W. C. (2020). Unbiased proteomics identifies plasminogen activator inhibitor-1 as a negative regulator of endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America, 117(17), 9497-9507. https://doi.org/10.1073/pnas.1918761117

PMID: 32332750
Rodrigues, D. C., Harvey, E. M., Suraj, R., Erickson, S. L., Mohammad, L., Ren, M., Liu, H., He, G., Kaplan, D. R., Ellis, J., & Yang, G. (2020). Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells. Nature communications, 11(1), 2018. https://doi.org/10.1038/s41467-020-15941-2

PMID: 32332723
He, Y., Zhang, X., Chang, J., Kim, H. N., Zhang, P., Wang, Y., Khan, S., Liu, X., Zhang, X., Lv, D., Song, L., Li, W., Thummuri, D., Yuan, Y., Wiegand, J. S., Ortiz, Y. T., Budamagunta, V., Elisseeff, J. H., Campisi, J., Almeida, M., ? Zhou, D. (2020). Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity. Nature communications, 11(1), 1996. https://doi.org/10.1038/s41467-020-15838-0

PMID: 32315313
Carias, K. V., Zoeteman, M., Seewald, A., Sanderson, M. R., Bischof, J. M., & Wevrick, R. (2020). A MAGEL2-deubiquitinase complex modulates the ubiquitination of circadian rhythm protein CRY1. PloS one, 15(4), e0230874. https://doi.org/10.1371/journal.pone.0230874

PMID: 32128584
Kramarski, L., & Arbely, E. (2020). Translational read-through promotes aggregation and shapes stop codon identity. Nucleic acids research, 48(7), 3747-3760. https://doi.org/10.1093/nar/gkaa136

PMID: 32494070
von Appen, A., LaJoie, D., Johnson, I. E., Trnka, M. J., Pick, S. M., Burlingame, A. L., Ullman, K. S., & Frost, A. (2020). LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation. Nature, 582 (7810), 115-118. https://doi.org/10.1038/s41586-020-2232-x

PMID: 31974114
Fray, M. A., Charpentier, J. C., Sylvain, N. R., Seminario, M. C., & Bunnell, S. C. (2020). Vav2 lacks Ca2+ entry-promoting scaffolding functions unique to Vav1 and inhibits T cell activation via Cdc42. Journal of cell science, 133(5), jcs238337. https://doi.org/10.1242/jcs.238337

PMID: 32134147
Schwörer, S., Berisa, M., Violante, S., Qin, W., Zhu, J., Hendrickson, R. C., Cross, J. R., & Thompson, C. B. (2020). Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress. The EMBO journal, 39(8), e103334. https://doi.org/10.15252/embj.2019103334

PMID: 32198144
Lauenstein, J. U., Scherm, M. J., Udgata, A., Moncrieffe, M. C., Fisher, D. I., & Gay, N. J. (2020). Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain. Journal of immunology (Baltimore, Md. : 1950), 204(8), 2269-2276. https://doi.org/10.4049/jimmunol.1901210

PMID: 32142641
Zook, J., Shekhar, M., Hansen, D., Conrad, C., Grant, T., Gupta, C., White, T., Barty, A., Basu, S., Zhao, Y., Zatsepin, N., Ishchenko, A., Batyuk, A., Gati, C., Li, C., Galli, L., Coe, J., Hunter, M., Liang, M., Weierstall, U., ? Fromme, P. (2020). XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia. Structure (London, England : 1993), 28(5), 540-547.e3. https://doi.org/10.1016/j.str.2020.02.005

PMID: 32169520
Satyam, R., Bhardwaj, T., Jha, N. K., Jha, S. K., & Nand, P. (2020). Toward a chimeric vaccine against multiple isolates of Mycobacteroides - An integrative approach. Life sciences, 250, 117541. https://doi.org/10.1016/j.lfs.2020.117541

PMID: 33345196
Hulton, C. H., Costa, E. A., Shah, N. S., Quintanal-Villalonga, A., Heller, G., de Stanchina, E., Rudin, C. M., & Poirier, J. T. (2020). Direct genome editing of patient-derived xenografts using CRISPR-Cas9 enables rapid in vivo functional genomics. Nature cancer, 1(3), 359-369. https://doi.org/10.1038/s43018-020-0040-8

PMID: 32195353
Liu, Y., Fan, J., Xu, T., Ahmadinejad, N., Hess, K., Lin, S. H., Zhang, J., Liu, X., Liu, L., Ning, B., Liao, Z., & Hu, T. Y. (2020). Extracellular vesicle tetraspanin-8 level predicts distant metastasis in non-small cell lung cancer after concurrent chemoradiation. Science advances, 6(11), eaaz6162. https://doi.org/10.1126/sciadv.aaz6162

PMID: 32198351
von Roemeling, C. A., Wang, Y., Qie, Y., Yuan, H., Zhao, H., Liu, X., Yang, Z., Yang, M., Deng, W., Bruno, K. A., Chan, C. K., Lee, A. S., Rosenfeld, S. S., Yun, K., Johnson, A. J., Mitchell, D. A., Jiang, W., & Kim, B. (2020). Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nature communications, 11(1), 1508. https://doi.org/10.1038/s41467-020-15129-8

PMID: 32182256
Bun, J. S., Slack, M. D., Schemenauer, D. E., & Johnson, R. J. (2020). Comparative analysis of the human serine hydrolase OVCA2 to the model serine hydrolase homolog FSH1 from S. cerevisiae. PloS one, 15 (3), e0230166. https://doi.org/10.1371/journal.pone.0230166

PMID: 32431828
Bromberg, R., Guo, Y., Borek, D., & Otwinowski, Z. (2020). High-resolution cryo-EM reconstructions in the presence of substantial aberrations. IUCrJ, 7(Pt 3), 445-452. https://doi.org/10.1107/S2052252520002444

PMID: 32017351
Goser V, Kehl A, Roder J., & Hensel M. (2020). Role of the ESCRT-III complex in controlling integrity of the Salmonella-containing vacuole. Cell Microbiol, 22(6), e13176. https://doi.org/10.1111/cmi.13176

PMID: 32037094
Kumari, R., Jiu, Y., Carman, P. J., Tojkander, S., Kogan, K., Varjosalo, M., Gunning, P. W., Dominguez, R., & Lappalainen, P. (2020). Tropomodulins Control the Balance between Protrusive and Contractile Structures by Stabilizing Actin-Tropomyosin Filaments. Current biology : CB, 30(5), 767-778.e5. https://doi.org/10.1016/j.cub.2019.12.049

PMID: 32071084
Lear, T. B., Lockwood, K. C., Larsen, M., Tuncer, F., Kennerdell, J. R., Morse, C., Valenzi, E., Tabib, T., Jurczak, M. J., Kass, D. J., Evankovich, J. W., Finkel, T., Lafyatis, R., Liu, Y., & Chen, B. B. (2020). Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis. The Journal of biological chemistry, 295(13), 4171-4180. https://doi.org/10.1074/jbc.AC119.012066

PMID: 31872936
Röder, J., & Hensel, M. (2020). Presence of SopE and mode of infection result in increased Salmonella-containing vacuole damage and cytosolic release during host cell infection by Salmonella enterica. Cellular microbiology, 22(5), e13155. https://doi.org/10.1111/cmi.13155

PMID: 31769662
Palanirajan, S. K., & Gummadi, S. N. (2020). Heavy-Metals-Mediated Phospholipids Scrambling by Human Phospholipid Scramblase 3: A Probable Role in Mitochondrial Apoptosis. Chemical research in toxicology, 33(2), 553-564. https://doi.org/10.1021/acs.chemrestox.9b00406

PMID: 31812387
Hakim Elahi, S., Abbaszadegan, M., & Conroy-Ben, O. (2020). Engineered proteoliposome transporter for treatment of cesium contaminated water. The Science of the total environment, 704, 135317. https://doi.org/10.1016/j.scitotenv.2019.135317

PMID: 31695151
Wang, Z., Li, Y., Wu, D., Yu, S., Wang, Y., & Leung Chan, F. (2020). Nuclear receptor HNF4α performs a tumor suppressor function in prostate cancer via its induction of p21-driven cellular senescence. Oncogene, 39(7), 1572-1589. https://doi.org/10.1038/s41388-019-1080-3

PMID: 32086320
Tran-Nguyen, T. K., Chandra, D., Yuan, K., Patibandla, P. K., Nguyen, K. T., Sethu, P., Zhang, Y., Xue, J., Mobley, J. A., Kim, Y. I., Shoushtari, A., Leader, J. K., Bon, J., Sciurba, F. C., & Duncan, S. R. (2020). Glucose-Regulated Protein 78 Autoantibodies Are Associated with Carotid Atherosclerosis in Chronic Obstructive Pulmonary Disease Patients. ImmunoHorizons, 4(2), 108-118. https://doi.org/10.4049/immunohorizons.1900098

PMID: 32101743
Harrison, O. J., Brasch, J., Katsamba, P. S., Ahlsen, G., Noble, A. J., Dan, H., Sampogna, R. V., Potter, C. S., Carragher, B., Honig, B., & Shapiro, L. (2020). Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered δ-Protocadherins. Cell reports, 30(8), 2655-2671.e7. https://doi.org/10.1016/j.celrep.2020.02.003

PMID: 32060313
Trastoy, B., Du, J. J., Klontz, E. H., Li, C., Cifuente, J. O., Wang, L. X., Sundberg, E. J., & Guerin, M. E. (2020). Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides. Nature communications, 11(1), 899. https://doi.org/10.1038/s41467-020-14754-7

PMID: 31807968
Nagaroor, V., & Gummadi, S. N. (2020). Biochemical characterization of an esterase from Clostridium acetobutylicum with novel GYSMG pentapeptide motif at the catalytic domain. Journal of industrial microbiology & biotechnology, 47(2), 169-181. https://doi.org/10.1007/s10295-019-02253-8

PMID: 32194852
Garranzo-Asensio, M., Guzmán-Aránguez, A., Povedano, E., Ruiz-Valdepeñas Montiel, V., Poves, C., Fernandez-Aceñero, M. J., Montero-Calle, A., Solís-Fernández, G., Fernandez-Diez, S., Camps, J., Arenas, M., Rodríguez-Tomàs, E., Joven, J., Sanchez-Martinez, M., Rodriguez, N., Dominguez, G., Yáñez-Sedeño, P., Pingarrón, J. M., Campuzano, S., & Barderas, R. (2020). Multiplexed monitoring of a novel autoantibody diagnostic signature of colorectal cancer using HaloTag technology-based electrochemical immunosensing platform. Theranostics, 10(7), 3022-3034. https://doi.org/10.7150/thno.42507

PMID: 31969655
Darvish, H., Azcona, L. J., Tafakhori, A., Mesias, R., Ahmadifard, A., Sanchez, E., Habibi, A., Alehabib, E., Johari, A. H., Emamalizadeh, B., Jamali, F., Chapi, M., Jamshidi, J., Kajiwara, Y., & Paisan-Ruiz, C. (2020). Phenotypic and genotypic characterization of families with complex intellectual disability identified pathogenic genetic variations in known and novel disease genes. Scientific reports, 10(1), 968. https://doi.org/10.1038/s41598-020-57929-4

PMID: 31992623
Green, R. S., Naimi, W. A., Oliver, L. D., Jr, O'Bier, N., Cho, J., Conrad, D. H., Martin, R. K., Marconi, R. T., & Carlyon, J. A. (2020). Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection. mBio, 11(1), e03141-19. https://doi.org/10.1128/mBio.03141-19

PMID: 31995744
Moncrieffe, M. C., Bollschweiler, D., Li, B., Penczek, P. A., Hopkins, L., Bryant, C. E., Klenerman, D., & Gay, N. J. (2020). MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling. Structure (London, England : 1993), 28(3), 281-289.e3. https://doi.org/10.1016/j.str.2020.01.003

PMID: 31923473
Schmoker, A. M., Perez Pearson, L. M., Cruz, C., Colon Flores, L. G., Branfeild, S., Pagan Torres, F. D., Fonseca, K., Cantres, Y. M., Salgado Ramirez, C. A., Melendez, L. M., Ballif, B. A., & Washington, A. V. (2020). Defining the TLT-1 interactome from resting and activated human platelets. Journal of proteomics, 215, 103638. https://doi.org/10.1016/j.jprot.2020.103638

PMID: 31988042
Samuel, R. Z., Lei, P., Nam, K., Baker, O. J., & Andreadis, S. T. (2020). Engineering the mode of morphogenetic signal presentation to promote branching from salivary gland spheroids in 3D hydrogels. Acta biomaterialia, 105, 121-130. https://doi.org/10.1016/j.actbio.2020.01.027

PMID: 31918032
Garranzo-Asensio, M., San Segundo-Acosta, P., Povés, C., Fernández-Aceñero, M. J., Martínez-Useros, J., Montero-Calle, A., Solís-Fernández, G., Sanchez-Martinez, M., Rodríguez, N., Cerón, M. Á., Fernandez-Diez, S., Domínguez, G., de Los Ríos, V., Peláez-García, A., Guzmán-Aránguez, A., & Barderas, R. (2020). Identification of tumor-associated antigens with diagnostic ability of colorectal cancer by in-depth immunomic and seroproteomic analysis. Journal of proteomics, 214, 103635. https://doi.org/10.1016/j.jprot.2020.103635

PMID: 31995728
Jia, J., Bissa, B., Brecht, L., Allers, L., Choi, S. W., Gu, Y., Zbinden, M., Burge, M. R., Timmins, G., Hallows, K., Behrends, C., & Deretic, V. (2020). AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System. Molecular cell, 77(5), 951-969.e9. https://doi.org/10.1016/j.molcel.2019.12.028

PMID: 31911550
Mukhopadhyay, S., Goswami, D., Adiseshaiah, P. P., Burgan, W., Yi, M., Guerin, T. M., Kozlov, S. V., Nissley, D. V., & McCormick, F. (2020). Undermining Glutaminolysis Bolsters Chemotherapy While NRF2 Promotes Chemoresistance in KRAS-Driven Pancreatic Cancers. Cancer research, 80(8), 1630-1643. https://doi.org/10.1158/0008-5472.CAN-19-1363

PMID: 31541192
O'Connor, C. M., Leonard, D., Wiredja, D., Avelar, R. A., Wang, Z., Schlatzer, D., Bryson, B., Tokala, E., Taylor, S. E., Upadhyay, A., Sangodkar, J., Gingras, A. C., Westermarck, J., Xu, W., DiFeo, A., Brautigan, D. L., Haider, S., Jackson, M., & Narla, G. (2020). Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors. Oncogene, 39(3), 703-717. https://doi.org/10.1038/s41388-019-1012-2

PMID: 31899476
Acharya, S., Dutta, S., & Bose, K. (2020). A distinct concerted mechanism of structural dynamism defines activity of human serine protease HtrA3. The Biochemical journal, 477(2), 407-429. https://doi.org/10.1042/BCJ20190706

PMID: 31947658
Barrett, C. M., McCracken, R., Elmer, J., & Haynes, K. A. (2020). Components from the Human c-myb Transcriptional Regulation System Reactivate Epigenetically Repressed Transgenes. International journal of molecular sciences, 21 (2), 530. https://doi.org/10.3390/ijms21020530

PMID: 31571292
Babagana, M., Kichina, J. V., Slabodkin, H., Johnson, S., Maslov, A., Brown, L., Attwood, K., Nikiforov, M. A., & Kandel, E. S. (2020). The role of polo-like kinase 3 in the response of BRAF-mutant cells to targeted anticancer therapies. Molecular carcinogenesis, 59(1), 5-14. https://doi.org/10.1002/mc.23123

PMID: 31969655
Darvish, H., Azcona, L. J., Tafakhori, A., Mesias, R., Ahmadifard, A., Sanchez, E., Habibi, A., Alehabib, E., Johari, A. H., Emamalizadeh, B., Jamali, F., Chapi, M., Jamshidi, J., Kajiwara, Y., & Paisan-Ruiz, C. (2020). Phenotypic and genotypic characterization of families with complex intellectual disability identified pathogenic genetic variations in known and novel disease genes. Scientific reports, 10(1), 968. https://doi.org/10.1038/s41598-020-57929-4

PMID: 31777917
Spadotto, V., Giambruno, R., Massignani, E., Mihailovich, M., Maniaci, M., Patuzzo, F., Ghini, F., Nicassio, F., & Bonaldi, T. (2020). PRMT1-mediated methylation of the microprocessor-associated proteins regulates microRNA biogenesis. Nucleic acids research, 48(1), 96-115. https://doi.org/10.1093/nar/gkz1051

PMID: 31624087
Kosti, A., Du, L., Shivram, H., Qiao, M., Burns, S., Garcia, J. G., Pertsemlidis, A., Iyer, V. R., Kokovay, E., & Penalva, L. (2020). ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State. Molecular cancer research : MCR, 18(1), 68-78. https://doi.org/10.1158/1541-7786.MCR-19-0187

PMID: 31967103
Daer, R., Hamna, F., Barrett, C. M., & Haynes, K. A. (2020). Site-directed targeting of transcriptional activation-associated proteins to repressed chromatin restores CRISPR activity. APL bioengineering, 4(1), 016102. https://doi.org/10.1063/1.5127302

PMID: 31813797
Jia, J., Claude-Taupin, A., Gu, Y., Choi, S. W., Peters, R., Bissa, B., Mudd, M. H., Allers, L., Pallikkuth, S., Lidke, K. A., Salemi, M., Phinney, B., Mari, M., Reggiori, F., & Deretic, V. (2020). Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal. Developmental cell, 52(1), 69-87.e8. https://doi.org/10.1016/j.devcel.2019.10.025

PMID: 31527084
Lauenstein, J. U., Udgata, A., Bartram, A., De Sutter, D., Fisher, D. I., Halabi, S., Eyckerman, S., & Gay, N. J. (2019). Phosphorylation of the multifunctional signal transducer B-cell adaptor protein (BCAP) promotes recruitment of multiple SH2/SH3 proteins including GRB2. The Journal of biological chemistry, 294(52), 19852-19861. https://doi.org/10.1074/jbc.RA119.009931

PMID: 31852888
Marg, A., Escobar, H., Karaiskos, N., Grunwald, S. A., Metzler, E., Kieshauer, J., Sauer, S., Pasemann, D., Malfatti, E., Mompoint, D., Quijano-Roy, S., Boltengagen, A., Schneider, J., Schülke, M., Kunz, S., Carlier, R., Birchmeier, C., Amthor, H., Spuler, A., Kocks, C., ? Spuler, S. (2019). Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7. Nature communications, 10(1), 5776. https://doi.org/10.1038/s41467-019-13650-z

PMID: 31792461
Khan, S., Zhang, X., Lv, D., Zhang, Q., He, Y., Zhang, P., Liu, X., Thummuri, D., Yuan, Y., Wiegand, J. S., Pei, J., Zhang, W., Sharma, A., McCurdy, C. R., Kuruvilla, V. M., Baran, N., Ferrando, A. A., Kim, Y. M., Rogojina, A., Houghton, P. J., ? Zhou, D. (2019). A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nature medicine, 25(12), 1938-1947. https://doi.org/10.1038/s41591-019-0668-z

PMID: 31448567
Kanthaswamy, S., Oldt, R. F., Said, R., Grijalva, J., Falak, A., Jensen, A., Vizor, C., Houghton, P., Bunlungsup, S., Malaivijitnond, S., & Smith, D. G. (2019). Partial sequence analyses of exon 7 of the ABO locus of cynomolgus (Macaca fascicularis) and rhesus (M. mulatta) macaques: Indeterminate phenotypes show the presence of the O blood group. HLA, 94(6), 482-492. https://doi.org/10.1111/tan.13675

PMID: 31066545
Rogers, M. S., & Lipscomb, J. D. (2019). Salicylate 5-Hydroxylase: Intermediates in Aromatic Hydroxylation by a Rieske Monooxygenase. Biochemistry, 58(52), 5305-5319. https://doi.org/10.1021/acs.biochem.9b00292

PMID: 31851935
Hart, P. C., Kenny, H. A., Grassl, N., Watters, K. M., Litchfield, L. M., Coscia, F., Blaženović, I., Ploetzky, L., Fiehn, O., Mann, M., Lengyel, E., & Romero, I. L. (2019). Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk. Cell reports, 29(12), 4086-4098.e6. https://doi.org/10.1016/j.celrep.2019.11.079

PMID: 31682764
Helassa, N., Nugues, C., Rajamanoharan, D., Burgoyne, R. D., & Haynes, L. P. (2019). A centrosome-localized calcium signal is essential for mammalian cell mitosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(12), 14602-14610. https://doi.org/10.1096/fj.201901662R

PMID: 31585128
Maraldi, T., Beretti, F., Anselmi, L., Franchin, C., Arrigoni, G., Braglia, L., Mandrioli, J., Vinceti, M., & Marmiroli, S. (2019). Influence of selenium on the emergence of neuro tubule defects in a neuron-like cell line and its implications for amyotrophic lateral sclerosis. Neurotoxicology, 75, 209-220. https://doi.org/10.1016/j.neuro.2019.09.015

PMID: 31976328
Yang, Y., He, J., Chen, J., Lin, L., Liu, Y., Zhou, C., Su, Y., & Wei, H. (2019). Dihydroartemisinin Sensitizes Mutant p53 (R248Q)-Expressing Hepatocellular Carcinoma Cells to Doxorubicin by Inhibiting P-gp Expression. BioMed research international, 2019, 8207056. https://doi.org/10.1155/2019/8207056

PMID: 31463572
Donkervoort, S., Sabouny, R., Yun, P., Gauquelin, L., Chao, K. R., Hu, Y., Al Khatib, I., Töpf, A., Mohassel, P., Cummings, B. B., Kaur, R., Saade, D., Moore, S. A., Waddell, L. B., Farrar, M. A., Goodrich, J. K., Uapinyoying, P., Chan, S., Javed, A., Leach, M. E., ? Shutt, T. E. (2019). MSTO1 mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement. Acta neuropathologica, 138(6), 1013-1031. https://doi.org/10.1007/s00401-019-02059-z

PMID: 31471297
Camacho-Encina, M., Balboa-Barreiro, V., Rego-Perez, I., Picchi, F., VanDuin, J., Qiu, J., Fuentes, M., Oreiro, N., LaBaer, J., Ruiz-Romero, C., & Blanco, F. J. (2019). Discovery of an autoantibody signature for the early diagnosis of knee osteoarthritis: data from the Osteoarthritis Initiative. Annals of the rheumatic diseases, 78(12), 1699-1705. https://doi.org/10.1136/annrheumdis-2019-215325

PMID: 31562245
Perl, A. L., O'Connor, C. M., Fa, P., Mayca Pozo, F., Zhang, J., Zhang, Y., & Narla, G. (2019). Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45). The Journal of biological chemistry, 294(45), 17043-17059. https://doi.org/10.1074/jbc.RA119.010432

PMID: 31738162
Herring, S. K., Moon, H. J., Rawal, P., Chhibber, A., & Zhao, L. (2019). Brain clusterin protein isoforms and mitochondrial localization. eLife, 8, e48255. https://doi.org/10.7554/eLife.48255

PMID: 31625181
Gu, Y., Princely Abudu, Y., Kumar, S., Bissa, B., Choi, S. W., Jia, J., Lazarou, M., Eskelinen, E. L., Johansen, T., & Deretic, V. (2019). Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs. The EMBO journal, 38(22), e101994. https://doi.org/10.15252/embj.2019101994

PMID: 31445086
Chellam Gayathri, S., & Manoj, N. (2019). Structural insights into the mechanism of internal aldimine formation and catalytic loop dynamics in an archaeal Group II decarboxylase. Journal of structural biology, 208 (2), 137-151. https://doi.org/10.1016/j.jsb.2019.08.009

PMID: 31141475
Schlachter, C. R., Klapper, V., Radford, T., & Chruszcz, M. (2019). Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biological chemistry, 400(12), 1567-1581. https://doi.org/10.1515/hsz-2019-0106

PMID: 31633707
Goklany, S., Lu, P., Godeshala, S., Hall, A., Garrett-Mayer, E., Voelkel-Johnson, C., & Rege, K. (2019). Delivery of TRAIL-expressing plasmid DNA to cancer cells in vitro and in vivo using aminoglycoside-derived polymers. Journal of materials chemistry. B, 7(44), 7014-7025. https://doi.org/10.1039/c9tb01286a

PMID: 31747592
Larson, G. P., Tran, V., Yú, S., Caì, Y., Higgins, C. A., Smith, D. M., Baker, S. F., Radoshitzky, S. R., Kuhn, J. H., & Mehle, A. (2019). EPS8 Facilitates Uncoating of Influenza A Virus. Cell reports, 29(8), 2175-2183.e4. https://doi.org/10.1016/j.celrep.2019.10.064

PMID: 31428784
Standage-Beier, K., Tekel, S. J., Brookhouser, N., Schwarz, G., Nguyen, T., Wang, X., & Brafman, D. A. (2019). A transient reporter for editing enrichment (TREE) in human cells. Nucleic acids research, 47(19), e120. https://doi.org/10.1093/nar/gkz713

PMID: 31607565
Zhu, J., Berisa, M., Schworer, S., Qin, W., Cross, J. R., & Thompson, C. B. (2019). Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation. Cell metabolism, 30(5), 865-876.e5. https://doi.org/10.1016/j.cmet.2019.09.009

PMID: 31604910
Cai, D., Wang, J., Gao, B., Li, J., Wu, F., Zou, J. X., Xu, J., Jiang, Y., Zou, H., Huang, Z., Borowsky, A. D., Bold, R. J., Lara, P. N., Li, J. J., Chen, X., Lam, K. S., To, K. F., Kung, H. J., Fiehn, O., Zhao, R., ? Chen, H. W. (2019). RORΓ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nature communications, 10(1), 4621. https://doi.org/10.1038/s41467-019-12529-3

PMID: 31663850
Vierra, N. C., Kirmiz, M., van der List, D., Santana, L. F., & Trimmer, J. S. (2019). Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons. eLife, 8, e49953. https://doi.org/10.7554/eLife.49953

PMID: 31504787
Tang, S., Hicks, N. D., Cheng, Y. S., Silva, A., Fortune, S. M., & Sacchettini, J. C. (2019). Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor. Nucleic acids research, 47(18), 9934-9949. https://doi.org/10.1093/nar/gkz724

PMID: 31492633
Beaumatin, F., O'Prey, J., Barthet, V., Zunino, B., Parvy, J. P., Bachmann, A. M., O'Prey, M., Kania, E., Gonzalez, P. S., Macintosh, R., Lao, L. Y., Nixon, C., Lopez, J., Long, J. S., Tait, S., & Ryan, K. M. (2019). mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux. Molecular cell, 76(1), 163-176.e8. https://doi.org/10.1016/j.molcel.2019.07.021

PMID: 31710025
Festa, F., & Labaer, J. (2019). Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays. Journal of visualized experiments : JoVE, (152), 10.3791/59886. https://doi.org/10.3791/59886

PMID: 31409483
Mohapatra, S. B., & Manoj, N. (2019). Structure of an α-glucuronidase in complex with Co2+ and citrate provides insights into the mechanism and substrate recognition in the family 4 glycosyl hydrolases. Biochemical and biophysical research communications, 518(2), 197-203. https://doi.org/10.1016/j.bbrc.2019.08.030

PMID: 31657440
Marbaix, A. Y., Chehade, G., Noël, G., Morsomme, P., Vertommen, D., Bommer, G. T., & Van Schaftingen, E. (2019). Pyridoxamine-phosphate oxidases and pyridoxamine-phosphate oxidase-related proteins catalyze the oxidation of 6-NAD(P)H to NAD(P). The Biochemical journal, 476(20), 3033-3052. https://doi.org/10.1042/BCJ20190602

PMID: 31578439
Shen, L., Zhang, J., Lee, H., Batista, M. T., & Johnston, S. A. (2019). RNA Transcription and Splicing Errors as a Source of Cancer Frameshift Neoantigens for Vaccines. Scientific reports, 9(1), 14184. https://doi.org/10.1038/s41598-019-50738-4

PMID: 31306512
Xu, Q., Biancalana, M., Grant, J. C., Chiu, H. J., Jaroszewski, L., Knuth, M. W., Lesley, S. A., Godzik, A., Elsliger, M. A., Deacon, A. M., & Wilson, I. A. (2019). Structures of single-layer β-sheet proteins evolved from β-hairpin repeats. Protein science : a publication of the Protein Society, 28(9), 1676-1689. https://doi.org/10.1002/pro.3683

PMID: 31553912
Elman, J. S., Ni, T. K., Mengwasser, K. E., Jin, D., Wronski, A., Elledge, S. J., & Kuperwasser, C. (2019). Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing. Cell reports, 28(13), 3435-3449.e5. https://doi.org/10.1016/j.celrep.2019.08.060

PMID: 31420518
Geng, J., & Raghavan, M. (2019). CD8αα homodimers function as a coreceptor for KIR3DL1. Proceedings of the National Academy of Sciences of the United States of America, 116(36), 17951-17956. https://doi.org/10.1073/pnas.1905943116

PMID: 31306516
Huang, M. S., Lin, W. C., Chang, J. H., Cheng, C. H., Wang, H. Y., & Mou, K. Y. (2019). The cysteine-free single mutant C32S of APEX2 is a highly expressed and active fusion tag for proximity labeling applications. Protein science : a publication of the Protein Society, 28(9), 1703-1712. https://doi.org/10.1002/pro.3685

PMID: 31484063
Yang, W. H., Ding, C. C., Sun, T., Rupprecht, G., Lin, C. C., Hsu, D., & Chi, J. T. (2019). The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma. Cell reports, 28(10), 2501-2508.e4. https://doi.org/10.1016/j.celrep.2019.07.107

PMID: 31553912
Elman, J. S., Ni, T. K., Mengwasser, K. E., Jin, D., Wronski, A., Elledge, S. J., & Kuperwasser, C. (2019). Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing. Cell reports, 28(13), 3435-3449.e5. https://doi.org/10.1016/j.celrep.2019.08.060

PMID: 31517450
Souza, S. A., Kurohara, D. T., Dabalos, C. L., & Ng, H. L. (2019). G Protein-Coupled Estrogen Receptor Production Using an Escherichia coli Cell-Free Expression System. Current protocols in protein science, 97(1), e88. https://doi.org/10.1002/cpps.88

PMID: 31537884
Garranzo-Asensio, M., Guzmán-Aránguez, A., Povés, C., Fernández-Aceñero, M. J., Montero-Calle, A., Ceron, M. Á., Fernandez-Diez, S., Rodríguez, N., Gómez de Cedrón, M., Ramírez de Molina, A., Domínguez, G., & Barderas, R. (2019). The specific seroreactivity to ΔNp73 isoforms shows higher diagnostic ability in colorectal cancer patients than the canonical p73 protein. Scientific reports, 9(1), 13547. https://doi.org/10.1038/s41598-019-49960-x

PMID: 31477691
Bushell, S. R., Pike, A., Falzone, M. E., Rorsman, N., Ta, C. M., Corey, R. A., Newport, T. D., Christianson, J. C., Scofano, L. F., Shintre, C. A., Tessitore, A., Chu, A., Wang, Q., Shrestha, L., Mukhopadhyay, S., Love, J. D., Burgess-Brown, N. A., Sitsapesan, R., Stansfeld, P. J., Huiskonen, J. T., ... Carpenter, E. P. (2019). The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Nature communications, 10(1), 3956. https://doi.org/10.1038/s41467-019-11753-1

PMID: 31391345
Ortiz, M. V., Ahmed, S., Burns, M., Henssen, A. G., Hollmann, T. J., MacArthur, I., Gunasekera, S., Gaewsky, L., Bradwin, G., Ryan, J., Letai, A., He, Y., Naranjo, A., Chi, Y. Y., LaQuaglia, M., Heaton, T., Cifani, P., Dome, J. S., Gadd, S., Perlman, E., ? Kentsis, A. (2019). Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor. JCI insight, 4(15), e127098. https://doi.org/10.1172/jci.insight.127098

PMID: 31451629
Zhu, F., Feng, M., Sinha, R., Murphy, M. P., Luo, F., Kao, K. S., Szade, K., Seita, J., & Weissman, I. L. (2019). The GABA receptor GABRR1 is expressed on and functional in hematopoietic stem cells and megakaryocyte progenitors. Proceedings of the National Academy of Sciences of the United States of America, 116(37), 18416-18422. https://doi.org/10.1073/pnas.1906251116

PMID: 31508486
Yu, X., Zhang, Y., Wu, B., Kurie, J. M., & Pertsemlidis, A. (2019). The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5. Molecular therapy oncolytics, 14, 288-298. https://doi.org/10.1016/j.omto.2019.07.004

PMID: 31436506
Standage-Beier, K., Brookhouser, N., Balachandran, P., Zhang, Q., Brafman, D. A., & Wang, X. (2019). RNA-Guided Recombinase-Cas9 Fusion Targets Genomic DNA Deletion and Integration. The CRISPR journal, 2(4), 209-222. https://doi.org/10.1089/crispr.2019.0013

PMID: 31461647
Kasitinon, S. Y., Eskiocak, U., Martin, M., Bezwada, D., Khivansara, V., Tasdogan, A., Zhao, Z., Mathews, T., Aurora, A. B., & Morrison, S. J. (2019). TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling. Cell reports, 28(9), 2293-2305.e9. https://doi.org/10.1016/j.celrep.2019.07.086

PMID: 31429216
Hanley, T., Yin, R., Mac, J., Tan, W., & Anvari, B. (2019). Functionalized erythrocyte-derived optical nanoparticles to target ephrin-B2 ligands. Journal of biomedical optics, 24(8), 1-9. https://doi.org/10.1117/1.JBO.24.8.085002

PMID: 31038200
Kurgan, G., Sievert, C., Flores, A., Schneider, A., Billings, T., Panyon, L., Morris, C., Taylor, E., Kurgan, L., Cartwright, R., & Wang, X. (2019). Parallel experimental evolution reveals a novel repressive control of GalP on xylose fermentation in Escherichia coli. Biotechnology and bioengineering, 116(8), 2074-2086. https://doi.org/10.1002/bit.27004

PMID: 31534541
Tang, X., McMullen, T., & Brindley, D. N. (2019). Increasing the low lipid phosphate phosphatase 1 activity in breast cancer cells decreases transcription by AP-1 and expressions of matrix metalloproteinases and cyclin D1/D3. Theranostics, 9(21), 6129-6142. https://doi.org/10.7150/thno.37094

PMID: 31341105
Ruiz, M., Cuillerier, A., Daneault, C., Deschênes, S., Frayne, I. R., Bouchard, B., Forest, A., Legault, J. T., LSFC Consortium, Vaz, F. M., Rioux, J. D., Burelle, Y., & Des Rosiers, C. (2019). Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder. JCI insight, 4(14), e123231. https://doi.org/10.1172/jci.insight.123231

PMID: 31182646
Bearrows, S. C., Bauchle, C. J., Becker, M., Haldeman, J. M., Swaminathan, S., & Stephens, S. B. (2019). Chromogranin B regulates early-stage insulin granule trafficking from the Golgi in pancreatic islet β-cells. Journal of cell science, 132(13), jcs231373. https://doi.org/10.1242/jcs.231373

PMID: 30914247
Stanford, K. R., Hadley, S. H., Barannikov, I., Ajmo, J. M., Bahia, P. K., & Taylor-Clark, T. E. (2019). Antimycin A-induced mitochondrial dysfunction activates vagal sensory neurons via ROS-dependent activation of TRPA1 and ROS-independent activation of TRPV1. Brain research, 1715, 94-105. https://doi.org/10.1016/j.brainres.2019.03.029

PMID: 31142615
Yoo, W., Cho, E. B., Kim, S., & Yoon, J. B. (2019). The E3 ubiquitin ligase MARCH2 regulates ERGIC3-dependent trafficking of secretory proteins. The Journal of biological chemistry, 294(28), 10900-10912. https://doi.org/10.1074/jbc.RA119.007435

PMID: 31308409
Jeyarajah, M. J., Jaju Bhattad, G., Kops, B. F., & Renaud, S. J. (2019). Syndecan-4 regulates extravillous trophoblast migration by coordinating protein kinase C activation. Scientific reports, 9(1), 10175. https://doi.org/10.1038/s41598-019-46599-6

PMID: 31167905
Wang, C., Jiang, S., Zhang, L., Li, D., Liang, J., Narita, Y., Hou, I., Zhong, Q., Gewurz, B. E., Teng, M., & Zhao, B. (2019). TAF Family Proteins and MEF2C Are Essential for Epstein-Barr Virus Super-Enhancer Activity. Journal of virology, 93(16), e00513-19. https://doi.org/10.1128/JVI.00513-19

PMID: 31330998
Manivannan, P., Reddy, V., Mukherjee, S., Clark, K. N., & Malathi, K. (2019). RNase L Induces Expression of A Novel Serine/Threonine Protein Kinase, DRAK1, to Promote Apoptosis. International journal of molecular sciences, 20(14), 3535. https://doi.org/10.3390/ijms20143535

PMID: 31308374
Serwas, N. K., Hoeger, B., Ardy, R. C., Stulz, S. V., Sui, Z., Memaran, N., Meeths, M., Krolo, A., Yuce Petronczki, O., Pfajfer, L., Hou, T. Z., Halliday, N., Santos-Valente, E., Kalinichenko, A., Kennedy, A., Mace, E. M., Mukherjee, M., Tesi, B., Schrempf, A., Pickl, W. F., ? Boztug, K. (2019). Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis. Nature communications, 10(1), 3106. https://doi.org/10.1038/s41467-019-10812-x

PMID: 31365872
Jiang, C., Trudeau, S. J., Cheong, T. C., Guo, R., Teng, M., Wang, L. W., Wang, Z., Pighi, C., Gautier-Courteille, C., Ma, Y., Jiang, S., Wang, C., Zhao, B., Paillard, L., Doench, J. G., Chiarle, R., & Gewurz, B. E. (2019). CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation. Cell reports, 28(5), 1307-1322.e8. https://doi.org/10.1016/j.celrep.2019.06.079

PMID: 31045216
Cohen, S., Kramarski, L., Levi, S., Deshe, N., Ben David, O., & Arbely, E. (2019). Nonsense mutation-dependent reinitiation of translation in mammalian cells. Nucleic acids research, 47(12), 6330-6338. https://doi.org/10.1093/nar/gkz319

PMID: 31291580
Zhang, K., Lv, D. W., & Li, R. (2019). Conserved Herpesvirus Protein Kinases Target SAMHD1 to Facilitate Virus Replication. Cell reports, 28(2), 449-459.e5. https://doi.org/10.1016/j.celrep.2019.04.020

PMID: 31283204
Shek, R., Hilaire, T., Sim, J., & French, J. B. (2019). Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily. Biochemistry, 58(30), 3280-3292. https://doi.org/10.1021/acs.biochem.9b00341

PMID: 31232685
Lukacs, M., Roberts, T., Chatuverdi, P., & Stottmann, R. W. (2019). Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival. eLife, 8, e45248. https://doi.org/10.7554/eLife.45248

PMID: 31244651
Pawar, G., Madden, J. C., Ebbrell, D., Firman, J. W., & Cronin, M. (2019). In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR. Frontiers in pharmacology, 10, 561. https://doi.org/10.3389/fphar.2019.00561

PMID: 31251786
Rushing, A. W., Rushing, B., Hoang, K., Sanders, S. V., Peloponese, J. M., Jr, Polakowski, N., & Lemasson, I. (2019). HTLV-1 basic leucine zipper factor protects cells from oxidative stress by upregulating expression of Heme Oxygenase I. PLoS pathogens, 15(6), e1007922. https://doi.org/10.1371/journal.ppat.1007922

PMID: 30834435
Li, D., & Mukhopadhyay, S. (2019). Functional analyses of the UDP-galactose transporter SLC35A2 using the binding of bacterial Shiga toxins as a novel activity assay. Glycobiology, 29(6), 490-503. https://doi.org/10.1093/glycob/cwz016

PMID: 31725811
Buehler, J., Carpenter, E., Zeltzer, S., Igarashi, S., Rak, M., Mikell, I., Nelson, J. A., & Goodrum, F. (2019). Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency. PLoS pathogens, 15(11), e1008037. https://doi.org/10.1371/journal.ppat.1008037

PMID: 30992322
Truong, D. D., Kratz, A., Park, J. G., Barrientos, E. S., Saini, H., Nguyen, T., Pockaj, B., Mouneimne, G., LaBaer, J., & Nikkhah, M. (2019). A Human Organotypic Microfluidic Tumor Model Permits Investigation of the Interplay between Patient-Derived Fibroblasts and Breast Cancer Cells. Cancer research, 79(12), 3139-3151. https://doi.org/10.1158/0008-5472.CAN-18-2293

PMID: 31199820
Dragovich, M. A., Adam, K., Strazza, M., Tocheva, A. S., Peled, M., & Mor, A. (2019). SLAMF6 clustering is required to augment T cell activation. PloS one, 14(6), e0218109. https://doi.org/10.1371/journal.pone.0218109

PMID: 31182131
Chien, M. H., Lin, Y. W., Wen, Y. C., Yang, Y. C., Hsiao, M., Chang, J. L., Huang, H. C., & Lee, W. J. (2019). Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis. Journal of experimental & clinical cancer research : CR, 38(1), 246. https://doi.org/10.1186/s13046-019-1247-3

PMID: 31170499
Belo, Y., Mielko, Z., Nudelman, H., Afek, A., Ben-David, O., Shahar, A., Zarivach, R., Gordan, R., & Arbely, E. (2019). Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine. Biochimica et biophysica acta. General subjects, 1863(9), 1343-1350. https://doi.org/10.1016/j.bbagen.2019.05.019

PMID: 33654782
Bajinting, A., & Ng, H. L. (2019). A Detailed Protocol for Large-scale Recombinant Expression and Validation of Human FGFR2 with Its Transmembrane and Extracellular Domains in Escherichia coli. Bio-protocol, 9(11), e3261. https://doi.org/10.21769/BioProtoc.3261

PMID: 31233557
Wessels, D. J., Pradhan, N., Park, Y. N., Klepitsch, M. A., Lusche, D. F., Daniels, K. J., Conway, K. D., Voss, E. R., Hegde, S. V., Conway, T. P., & Soll, D. R. (2019). Reciprocal signaling and direct physical interactions between fibroblasts and breast cancer cells in a 3D environment. PloS one, 14(6), e0218854. https://doi.org/10.1371/journal.pone.0218854

PMID: 31182137
Chang, W. M., Chang, Y. C., Yang, Y. C., Lin, S. K., Chang, P. M., & Hsiao, M. (2019). AKR1C1 controls cisplatin-resistance in head and neck squamous cell carcinoma through cross-talk with the STAT1/3 signaling pathway. Journal of experimental & clinical cancer research : CR, 38(1), 245. https://doi.org/10.1186/s13046-019-1256-2

PMID: 30952661
Yu, J., Deem, L. M., Crow, S. E., Deenik, J., & Penton, C. R. (2019). Comparative Metagenomics Reveals Enhanced Nutrient Cycling Potential after 2 Years of Biochar Amendment in a Tropical Oxisol. Applied and environmental microbiology, 85(11), e02957-18. https://doi.org/10.1128/AEM.02957-18

PMID: 31002508
Crespo, R. A., Dang, Q., Zhou, N. E., Guthrie, L. M., Snavely, T. C., Dong, W., Loesch, K. A., Suzuki, T., You, L., Wang, W., O'Malley, T., Parish, T., Olsen, D. B., & Sacchettini, J. C. (2019). Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. Journal of medicinal chemistry, 62(9), 4483-4499. https://doi.org/10.1021/acs.jmedchem.9b00020

PMID: 31063758
White, S. M., Avantaggiati, M. L., Nemazanyy, I., Di Poto, C., Yang, Y., Pende, M., Gibney, G. T., Ressom, H. W., Field, J., Atkins, M. B., & Yi, C. (2019). YAP/TAZ Inhibition Induces Metabolic and Signaling Rewiring Resulting in Targetable Vulnerabilities in NF2-Deficient Tumor Cells. Developmental cell, 49(3), 425-443.e9. https://doi.org/10.1016/j.devcel.2019.04.014

PMID: 32395093
Staup, A. J., De Silva, I. U., Catt, J. T., Tan, X., Hammond, R. G., & Johnson, M. A. (2019). Structure of the SARS-Unique Domain C From the Bat Coronavirus HKU4. Natural product communications, 14(5), 1934578X19849202. https://doi.org/10.1177/1934578X19849202

PMID: 30928616
Bartho, J. D., Demitri, N., Bellini, D., Flachowsky, H., Peil, A., Walsh, M. A., & Benini, S. (2019). The structure of Erwinia amylovora AvrRpt2 provides insight into protein maturation and induced resistance to fire blight by Malus × robusta 5. Journal of structural biology, 206(2), 233-242. https://doi.org/10.1016/j.jsb.2019.03.010

PMID: 31071193
Sun, L., Lee, H., Thibaut, H. J., Lanko, K., Rivero-Buceta, E., Bator, C., Martinez-Gualda, B., Dallmeier, K., Delang, L., Leyssen, P., Gago, F., San-Felix, A., Hafenstein, S., Mirabelli, C., & Neyts, J. (2019). Viral engagement with host receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid. PLoS pathogens, 15(5), e1007760. https://doi.org/10.1371/journal.ppat.1007760

PMID: 30772380
Rodrigues, C., Pattabiraman, C., Vijaykumar, A., Arora, R., Narayana, S. M., Kumar, R. V., Notani, D., Varga-Weisz, P., & Krishna, S. (2019). A SUV39H1-low chromatin state characterises and promotes migratory properties of cervical cancer cells. Experimental cell research, 378(2), 206-216. https://doi.org/10.1016/j.yexcr.2019.02.010

PMID: 30902545
Kumar, P., Rawat, K., Sharma, T., Kumari, S., Saxena, R., Kumar, B., Baghel, T., Afshan, T., Siddiqi, M. I., Nazir, A., Ghosh, J. K., & Tripathi, R. K. (2019). HIV-1 Nef physically associate with CAMKIIδ - ASK-1 complex to inhibit p38MAPK signalling and apoptosis in infected cells. Life sciences, 224, 263-273. https://doi.org/10.1016/j.lfs.2019.03.039

PMID: 31091453
Shami Shah, A., Batrouni, A. G., Kim, D., Punyala, A., Cao, W., Han, C., Goldberg, M. L., Smolka, M. B., & Baskin, J. M. (2019). PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling. Cell reports, 27(7), 2157-2170.e8. https://doi.org/10.1016/j.celrep.2019.04.060

PMID: 30962627
Ebrahimi, A., Sevinç, K., Gürhan Sevinç, G., Cribbs, A. P., Philpott, M., Uyulur, F., Morova, T., Dunford, J. E., Göklemez, S., Ari, S., Oppermann, U., & Önder, T. T. (2019). Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming. Nature chemical biology, 15(5), 519-528. https://doi.org/10.1038/s41589-019-0264-z

PMID: 31108937
Zhao, L., Zhao, Y., Tang, F. L., Xiong, L., Su, C., Mei, L., Zhu, X. J., & Xiong, W. C. (2019). pHluorin-BACE1-mCherry Acts as a Reporter for the Intracellular Distribution of Active BACE1 In Vitro and In Vivo. Cells, 8(5), 474. https://doi.org/10.3390/cells8050474

PMID: 31138786
Mandl, M., Wagner, S. A., Hatzmann, F. M., Mitterberger-Vogt, M. C., Zwierzina, M. E., Mattesich, M., & Zwerschke, W. (2019). Sprouty1 is a weight-loss target gene in human adipose stem/progenitor cells that is mandatory for the initiation of adipogenesis. Cell death & disease, 10(6), 411. https://doi.org/10.1038/s41419-019-1657-3

PMID: 30995470
Genga, R., Kernfeld, E. M., Parsi, K. M., Parsons, T. J., Ziller, M. J., & Maehr, R. (2019). Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. Cell reports, 27(3), 708-718.e10. https://doi.org/10.1016/j.celrep.2019.03.076

PMID: 30561643
Lahola-Chomiak, A. A., Footz, T., Nguyen-Phuoc, K., Neil, G. J., Fan, B., Allen, K. F., Greenfield, D. S., Parrish, R. K., Linkroum, K., Pasquale, L. R., Leonhardt, R. M., Ritch, R., Javadiyan, S., Craig, J. E., Allison, W. T., Lehmann, O. J., Walter, M. A., & Wiggs, J. L. (2019). Non-Synonymous variants in premelanosome protein (PMEL) cause ocular pigment dispersion and pigmentary glaucoma. Human molecular genetics, 28(8), 1298-1311. https://doi.org/10.1093/hmg/ddy429

PMID: 30796164
O'Connor, C. M., Hoffa, M. T., Taylor, S. E., Avelar, R. A., & Narla, G. (2019). Protein phosphatase 2A Aα regulates Aβ protein expression and stability. The Journal of biological chemistry, 294(15), 5923-5934. https://doi.org/10.1074/jbc.RA119.007593

PMID: 30837228
Wasiluk, T., Roueinfar, M., Hiryak, K., Torsiello, M., Miner, A., Lee, J., Venditto, M., Terzaghi, W., Lucent, D., & VanWert, A. L. (2019). Simultaneous expression of ClopHensor and SLC26A3 reveals the nature of endogenous oxalate transport in CHO cells. Biology open, 8(4), bio041665. https://doi.org/10.1242/bio.041665

PMID: 31015291
Hennigan, R. F., Fletcher, J. S., Guard, S., & Ratner, N. (2019). Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins. Science signaling, 12(578), eaau8749. https://doi.org/10.1126/scisignal.aau8749

PMID: 30894749
Liu, Z., Mar, K. B., Hanners, N. W., Perelman, S. S., Kanchwala, M., Xing, C., Schoggins, J. W., & Alto, N. M. (2019). A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. Nature, 568(7751), 249-253. https://doi.org/10.1038/s41586-019-1041-6

PMID: 30660564
Polsinelli, I., Caliandro, R., Salomone-Stagni, M., Demitri, N., Rejzek, M., Field, R. A., & Benini, S. (2019). Comparison of the Levansucrase from the epiphyte Erwinia tasmaniensis vs its homologue from the phytopathogen Erwinia amylovora. International journal of biological macromolecules, 127, 496-501. https://doi.org/10.1016/j.ijbiomac.2019.01.074

PMID: 31024343
Popov, I. K., Hiatt, S. M., Whalen, S., Keren, B., Ruivenkamp, C., van Haeringen, A., Chen, M. J., Cooper, G. M., Korf, B. R., & Chang, C. (2019). A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway. Frontiers in physiology, 10, 388. https://doi.org/10.3389/fphys.2019.00388

PMID: 31000703
Harnoš, J., Cañizal, M., Jurásek, M., Kumar, J., Holler, C., Schambony, A., Hanáková, K., Bernatík, O., Zdráhal, Z., Gömöryová, K., Gybel, T., Radaszkiewicz, T. W., Kravec, M., Trantírek, L., Ryneš, J., Dave, Z., Fernández-Llamazares, A. I., Vácha, R., Tripsianes, K., Hoffmann, C., ? Bryja, V. (2019). Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1. Nature communications, 10(1), 1804. https://doi.org/10.1038/s41467-019-09651-7

PMID: 30655321
Hart, P. C., Chiyoda, T., Liu, X., Weigert, M., Curtis, M., Chiang, C. Y., Loth, R., Lastra, R., McGregor, S. M., Locasale, J. W., Lengyel, E., & Romero, I. L. (2019). SPHK1 Is a Novel Target of Metformin in Ovarian Cancer. Molecular cancer research : MCR, 17(4), 870-881. https://doi.org/10.1158/1541-7786.MCR-18-0409

PMID: 31001086
Sanders, S. S., De Simone, F. I., & Thomas, G. M. (2019). mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR. Frontiers in cellular neuroscience, 13, 115. https://doi.org/10.3389/fncel.2019.00115

PMID: 30745430
Kumar, N., Tsai, Y. H., Chen, L., Zhou, A., Banerjee, K. K., Saxena, M., Huang, S., Toke, N. H., Xing, J., Shivdasani, R. A., Spence, J. R., & Verzi, M. P. (2019). The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development. Development (Cambridge, England), 146(5), dev172189. https://doi.org/10.1242/dev.172189

PMID: 30601698
Zhang, Y., Cao, F., Zhou, Y., Feng, Z., Sit, B., Krendel, M., & Yu, C. H. (2019). Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes. Molecular biology of the cell, 30(5), 622-635. https://doi.org/10.1091/mbc.E18-06-0398

PMID: 30893049
Zhang, P., Fan, B., Yang, P., Temirov, J., Messing, J., Kim, H. J., & Taylor, J. P. (2019). Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology. eLife, 8, e39578. https://doi.org/10.7554/eLife.39578

PMID: 30903020
Chen, Y., Xu, L., Mayakonda, A., Huang, M. L., Kanojia, D., Tan, T. Z., Dakle, P., Lin, R. Y., Ke, X. Y., Said, J. W., Chen, J., Gery, S., Ding, L. W., Jiang, Y. Y., Pang, A., Puhaindran, M. E., Goh, B. C., & Koeffler, H. P. (2019). Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma. Nature communications, 10(1), 1353. https://doi.org/10.1038/s41467-019-09257-z

PMID: 30872698
Yost, K. E., Clatterbuck Soper, S. F., Walker, R. L., Pineda, M. A., Zhu, Y. J., Ester, C. D., Showman, S., Roschke, A. V., Waterfall, J. J., & Meltzer, P. S. (2019). Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells. Scientific reports, 9(1), 4544. https://doi.org/10.1038/s41598-019-41058-8

PMID: 30914657
Chryplewicz, A., Tienda, S. M., Nahotko, D. A., Peters, P. N., Lengyel, E., & Eckert, M. A. (2019). Mutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6. Scientific reports, 9(1), 5195. https://doi.org/10.1038/s41598-019-41352-5

PMID: 30814732
Chen, J., López-Moyado, I. F., Seo, H., Lio, C. J., Hempleman, L. J., Sekiya, T., Yoshimura, A., Scott-Browne, J. P., & Rao, A. (2019). NR4A transcription factors limit CAR T cell function in solid tumours. Nature, 567(7749), 530-534. https://doi.org/10.1038/s41586-019-0985-x

PMID: 30898150
Kennedy, S. P., Han, J., Portman, N., Nobis, M., Hastings, J. F., Murphy, K. J., Latham, S. L., Cadell, A. L., Miladinovic, D., Marriott, G. R., O'Donnell, Y., Shearer, R. F., Williams, J. T., Munoz, A. G., Cox, T. R., Watkins, D. N., Saunders, D. N., Timpson, P., Lim, E., Kolch, W., ? Croucher, D. R. (2019). Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer. Breast cancer research : BCR, 21(1), 43. https://doi.org/10.1186/s13058-019-1127-y

PMID: 30626696
Lee, S., Salazar, S. V., Cox, T. O., & Strittmatter, S. M. (2019). Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss. The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(10), 1910-1929. https://doi.org/10.1523/JNEUROSCI.2983-18.2018

PMID: 30885209
Szymura, S. J., Zaemes, J. P., Allison, D. F., Clift, S. H., D'Innocenzi, J. M., Gray, L. G., McKenna, B. D., Morris, B. B., Bekiranov, S., LeGallo, R. D., Jones, D. R., & Mayo, M. W. (2019). NF-κB upregulates glutamine-fructose-6-phosphate transaminase¬¬ 2 to promote migration in non-small cell lung cancer. Cell communication and signaling : CCS, 17(1), 24. https://doi.org/10.1186/s12964-019-0335-5

PMID: 30590691
Haldeman, J. M., Conway, A. E., Arlotto, M. E., Slentz, D. H., Muoio, D. M., Becker, T. C., & Newgard, C. B. (2019). Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing. Nucleic acids research, 47(4), e23. https://doi.org/10.1093/nar/gky1286

PMID: 30661980
Lohman, D. C., Aydin, D., Von Bank, H. C., Smith, R. W., Linke, V., Weisenhorn, E., McDevitt, M. T., Hutchins, P., Wilkerson, E. M., Wancewicz, B., Russell, J., Stefely, M. S., Beebe, E. T., Jochem, A., Coon, J. J., Bingman, C. A., Dal Peraro, M., & Pagliarini, D. J. (2019). An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis. Molecular cell, 73(4), 763-774.e10. https://doi.org/10.1016/j.molcel.2018.11.033

PMID: 30581045
Peng, Y., Cao, S., Kiselar, J., Xiao, X., Du, Z., Hsieh, A., Ko, S., Chen, Y., Agrawal, P., Zheng, W., Shi, W., Jiang, W., Yang, L., Chance, M. R., Surewicz, W. K., Buck, M., & Yang, S. (2019). A Metastable Contact and Structural Disorder in the Estrogen Receptor Transactivation Domain. Structure (London, England : 1993), 27(2), 229-240.e4. https://doi.org/10.1016/j.str.2018.10.026

PMID: 30277820
Wu, D., Kanda, A., Liu, Y., Kase, S., Noda, K., & Ishida, S. (2019). Galectin-1 promotes choroidal neovascularization and subretinal fibrosis mediated via epithelial-mesenchymal transition. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(2), 2498-2513. https://doi.org/10.1096/fj.201801227R

PMID: 30728521
De Cecco, M., Ito, T., Petrashen, A. P., Elias, A. E., Skvir, N. J., Criscione, S. W., Caligiana, A., Brocculi, G., Adney, E. M., Boeke, J. D., Le, O., Beauséjour, C., Ambati, J., Ambati, K., Simon, M., Seluanov, A., Gorbunova, V., Slagboom, P. E., Helfand, S. L., Neretti, N., ? Sedivy, J. M. (2019). L1 drives IFN in senescent cells and promotes age-associated inflammation. Nature, 566(7742), 73-78. https://doi.org/10.1038/s41586-018-0784-9

PMID: 30498130
Villella, V. R., Venerando, A., Cozza, G., Esposito, S., Ferrari, E., Monzani, R., Spinella, M. C., Oikonomou, V., Renga, G., Tosco, A., Rossin, F., Guido, S., Silano, M., Garaci, E., Chao, Y. K., Grimm, C., Luciani, A., Romani, L., Piacentini, M., Raia, V., ? Maiuri, L. (2019). A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease. The EMBO journal, 38(2), e100101. https://doi.org/10.15252/embj.2018100101

PMID: 30538116
Cortes, E., Lachowski, D., Robinson, B., Sarper, M., Teppo, J. S., Thorpe, S. D., Lieberthal, T. J., Iwamoto, K., Lee, D. A., Okada-Hatakeyama, M., Varjosalo, M. T., & Del Rio Hernández, A. E. (2019). Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival. EMBO reports, 20(1), e46557. https://doi.org/10.15252/embr.201846557

PMID: 30948712
Lim, S., Hermance, N., Mudianto, T., Mustaly, H. M., Mauricio, I., Vittoria, M. A., Quinton, R. J., Howell, B. W., Cornils, H., Manning, A. L., & Ganem, N. J. (2019). Identification of the kinase STK25 as an upstream activator of LATS signaling. Nature communications, 10(1), 1547. https://doi.org/10.1038/s41467-019-09597-w

PMID: 31645561
Gupte, T. M., Ritt, M., Dysthe, M., Malik, R. U., & Sivaramakrishnan, S. (2019). Minute-scale persistence of a GPCR conformation state triggered by non-cognate G protein interactions primes signaling. Nature communications, 10(1), 4836. https://doi.org/10.1038/s41467-019-12755-9

PMID: 30683896
Insinna, C., Lu, Q., Teixeira, I., Harned, A., Semler, E. M., Stauffer, J., Magidson, V., Tiwari, A., Kenworthy, A. K., Narayan, K., & Westlake, C. J. (2019). Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. Nature communications, 10(1), 428. https://doi.org/10.1038/s41467-018-08192-9

PMID: 30174305
Curtis, M., Kenny, H. A., Ashcroft, B., Mukherjee, A., Johnson, A., Zhang, Y., Helou, Y., Batlle, R., Liu, X., Gutierrez, N., Gao, X., Yamada, S. D., Lastra, R., Montag, A., Ahsan, N., Locasale, J. W., Salomon, A. R., Nebreda, A. R., & Lengyel, E. (2019). Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis. Cell metabolism, 29(1), 141-155.e9. https://doi.org/10.1016/j.cmet.2018.08.007

PMID: 30315825
In 't Hout, F., van Duren, J., Monteferrario, D., Brinkhuis, E., Mariani, N., Westers, T. M., Chitu, D., Nikoloski, G., van de Loosdrecht, A. A., van der Reijden, B. A., Jansen, J. H., & Huls, G. (2019). TCF4 promotes erythroid development. Experimental hematology, 69, 17-21.e1. https://doi.org/10.1016/j.exphem.2018.10.002

PMID: 30708959
Ray, G., Schmitt, P. T., & Schmitt, A. P. (2019). Angiomotin-Like 1 Links Paramyxovirus M Proteins to NEDD4 Family Ubiquitin Ligases. Viruses, 11(2), 128. https://doi.org/10.3390/v11020128

PMID: 30523780
Makharashvili, N., Arora, S., Yin, Y., Fu, Q., Wen, X., Lee, J. H., Kao, C. H., Leung, J. W., Miller, K. M., & Paull, T. T. (2018). Sae2/CtIP prevents R-loop accumulation in eukaryotic cells. eLife, 7, e42733. https://doi.org/10.7554/eLife.42733

PMID: 30404791
Ariës, I. M., Bodaar, K., Karim, S. A., Chonghaile, T. N., Hinze, L., Burns, M. A., Pfirrmann, M., Degar, J., Landrigan, J. T., Balbach, S., Peirs, S., Menten, B., Isenhart, R., Stevenson, K. E., Neuberg, D. S., Devidas, M., Loh, M. L., Hunger, S. P., Teachey, D. T., Rabin, K. R., ? Gutierrez, A. (2018). PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia. The Journal of experimental medicine, 215(12), 3094-3114. https://doi.org/10.1084/jem.2018057

PMID: 30503706
Lu, B., Klingbeil, O., Tarumoto, Y., Somerville, T., Huang, Y. H., Wei, Y., Wai, D. C., Low, J., Milazzo, J. P., Wu, X. S., Cao, Z., Yan, X., Demerdash, O. E., Huang, G., Mackay, J. P., Kinney, J. B., Shi, J., & Vakoc, C. R. (2018). A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence. Cancer cell, 34(6), 970-981.e8. https://doi.org/10.1016/j.ccell.2018.10.015

PMID: 30520731
Pollak, A. J., Liu, C., Gudlur, A., Mayfield, J. E., Dalton, N. D., Gu, Y., Chen, J., Heller Brown, J., Hogan, P. G., Wiley, S. E., Peterson, K. L., & Dixon, J. E. (2018). A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure. eLife, 7, e41378. https://doi.org/10.7554/eLife.41378

PMID: 30332321
Dilsaver, M. R., Chen, P., Thompson, T. A., Reusser, T., Mukherjee, R. N., Oakey, J., & Levy, D. L. (2018). Emerin induces nuclear breakage in Xenopus extract and early embryos. Molecular biology of the cell, 29(26), 3155-3167. https://doi.org/10.1091/mbc.E18-05-0277

PMID: 30496488
Rusnak, L., Tang, C., Qi, Q., Mo, X., & Fu, H. (2018). Large tumor suppressor 2, LATS2, activates JNK in a kinase-independent mechanism through ASK1. Journal of molecular cell biology, 10(6), 549-558. https://doi.org/10.1093/jmcb/mjy061

PMID: 30242931
Deka, R. K., Liu, W. Z., Tso, S. C., Norgard, M. V., & Brautigam, C. A. (2018). Biophysical insights into a highly selective l-arginine-binding lipoprotein of a pathogenic treponeme. Protein science : a publication of the Protein Society, 27(12), 2037-2050. https://doi.org/10.1002/pro.3510

PMID: 30391463
Vekariya, U., Saxena, R., Singh, P., Rawat, K., Kumar, B., Kumari, S., Agnihotri, S. K., Kaur, S., Sachan, R., Nazir, A., Bhadauria, S., Sachdev, M., & Tripathi, R. K. (2018). HIV-1 Nef-POTEE; A novel interaction modulates macrophage dissemination via mTORC2 signaling pathway. Life sciences, 214, 158-166. https://doi.org/10.1016/j.lfs.2018.10.068

PMID: 30035326
Pizzute, T., He, F., Zhang, X. B., & Pei, M. (2018). Impact of Wnt signals on human intervertebral disc cell regeneration. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 36(12), 3196-3207. https://doi.org/10.1002/jor.24115

PMID: 30589867
Brenner, N., Mentzer, A. J., Butt, J., Michel, A., Prager, K., Brozy, J., Weiβbrich, B., Aiello, A. E., Meier, H., Breuer, J., Almond, R., Allen, N., Pawlita, M., & Waterboer, T. (2018). Validation of Multiplex Serology detecting human herpesviruses 1-5. PloS one, 13(12), e0209379. https://doi.org/10.1371/journal.pone.0209379

PMID: 30504831
Olthoff, J. T., Lindsay, A., Abo-Zahrah, R., Baltgalvis, K. A., Patrinostro, X., Belanto, J. J., Yu, D. Y., Perrin, B. J., Garry, D. J., Rodney, G. G., Lowe, D. A., & Ervasti, J. M. (2018). Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle. Nature communications, 9(1), 5104. https://doi.org/10.1038/s41467-018-07639-3

PMID: 30469546
Ting, C. H., Liu, Y. C., Lyu, P. C., & Chen, J. Y. (2018). Nile Tilapia Derived Antimicrobial Peptide TP4 Exerts Antineoplastic Activity Through Microtubule Disruption. Marine drugs, 16(12), 462. https://doi.org/10.3390/md16120462

PMID: 30478295
Zhang, J., Shen, L., & Johnston, S. A. (2018). Using Frameshift Peptide Arrays for Cancer Neo-Antigens Screening. Scientific reports, 8(1), 17366. https://doi.org/10.1038/s41598-018-35673-0

PMID: 30076647
Wu, J., Qin, W., Wang, Y., Sadik, A., Liu, J., Wang, Y., Song, P., Wang, X., Sun, K., Zeng, J., & Wang, L. (2018). SPDEF is overexpressed in gastric cancer and triggers cell proliferation by forming a positive regulation loop with FoxM1. Journal of cellular biochemistry, 119(11), 9042-9054. https://doi.org/10.1002/jcb.27161

PMID: 30275048
Peled, M., Dragovich, M. A., Adam, K., Strazza, M., Tocheva, A. S., Vega, I. E., & Mor, A. (2018). EF Hand Domain Family Member D2 Is Required for T Cell Cytotoxicity. Journal of immunology (Baltimore, Md. : 1950), 201(9), 2824-2831. https://doi.org/10.4049/jimmunol.1800839

PMID: 30366959
Ahmed, F., & Hristova, K. (2018). Dimerization of the Trk receptors in the plasma membrane: effects of their cognate ligands. The Biochemical journal, 475(22), 3669-3685. https://doi.org/10.1042/BCJ20180637

PMID: 30356053
Baronas, V. A., Yang, R. Y., Morales, L. C., Sipione, S., & Kurata, H. T. (2018). Slc7a5 regulates Kv1.2 channels and modifies functional outcomes of epilepsy-linked channel mutations. Nature communications, 9(1), 4417. https://doi.org/10.1038/s41467-018-06859-x

PMID: 30355501
Kosmidis, S., Polyzos, A., Harvey, L., Youssef, M., Denny, C. A., Dranovsky, A., & Kandel, E. R. (2018). RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. Cell reports, 25(4), 959-973.e6. https://doi.org/10.1016/j.celrep.2018.09.077

PMID: 30244836
Bouchard, J. J., Otero, J. H., Scott, D. C., Szulc, E., Martin, E. W., Sabri, N., Granata, D., Marzahn, M. R., Lindorff-Larsen, K., Salvatella, X., Schulman, B. A., & Mittag, T. (2018). Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments. Molecular cell, 72(1), 19-36.e8. https://doi.org/10.1016/j.molcel.2018.08.027

PMID: 30296254
Whelan, A. O., Flick-Smith, H. C., Homan, J., Shen, Z. T., Carpenter, Z., Khoshkenar, P., Abraham, A., Walker, N. J., Levitz, S. M., Ostroff, G. R., & Oyston, P. (2018). Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles. PloS one, 13(10), e0200213. https://doi.org/10.1371/journal.pone.0200213

PMID: 29933039
Brock, J. R., Donmez, A. A., Beilstein, M. A., & Olsen, K. M. (2018). Phylogenetics of Camelina Crantz. (Brassicaceae) and insights on the origin of gold-of-pleasure (Camelina sativa). Molecular phylogenetics and evolution, 127, 834-842. https://doi.org/10.1016/j.ympev.2018.06.031

PMID: 30171091
Zhao, K., Shen, C., Li, L., Wu, H., Xing, G., Dong, Z., Jing, H., Chen, W., Zhang, H., Tan, Z., Pan, J., Xiong, L., Wang, H., Cui, W., Sun, X. D., Li, S., Huang, X., Xiong, W. C., & Mei, L. (2018). Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4. The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(41), 8860-8873. https://doi.org/10.1523/JNEUROSCI.0860-18.2018

PMID: 30289412
Lountos, G. T., Raran-Kurussi, S., Zhao, B. M., Dyas, B. K., Burke, T. R., Jr, Ulrich, R. G., & Waugh, D. S. (2018). High-resolution crystal structures of the D1 and D2 domains of protein tyrosine phosphatase epsilon for structure-based drug design. Acta crystallographica. Section D, Structural biology, 74(Pt 10), 1015-1026. https://doi.org/10.1107/S2059798318011919

PMID: 30285805
Sethuraman, A., Brown, M., Krutilina, R., Wu, Z. H., Seagroves, T. N., Pfeffer, L. M., & Fan, M. (2018). BHLHE40 confers a pro-survival and pro-metastatic phenotype to breast cancer cells by modulating HBEGF secretion. Breast cancer research : BCR, 20(1), 117. https://doi.org/10.1186/s13058-018-1046-3

PMID: 30158125
Burgess, E. J., Hoyt, L. R., Randall, M. J., Mank, M. M., Bivona, J. J., 3rd, Eisenhauer, P. L., Botten, J. W., Ballif, B. A., Lam, Y. W., Wargo, M. J., Boyson, J. E., Ather, J. L., & Poynter, M. E. (2018). Bacterial Lipoproteins Constitute the TLR2-Stimulating Activity of Serum Amyloid A. Journal of immunology (Baltimore, Md. : 1950), 201(8), 2377-2384. https://doi.org/10.4049/jimmunol.1800503

PMID: 30256193
Scott, C. C., Vossio, S., Rougemont, J., & Gruenberg, J. (2018). TFAP2 transcription factors are regulators of lipid droplet biogenesis. eLife, 7, e36330. https://doi.org/10.7554/eLife.36330

PMID: 30241606
Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S. D., Lopez-Méndez, B., Nilsson, J., Mund, A., Mann, M., & Curtis, M. (2018). Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer. Cell, 175(1), 159-170.e16. https://doi.org/10.1016/j.cell.2018.08.065

PMID: 30184493
Baker, S. F., Ledwith, M. P., & Mehle, A. (2018). Differential Splicing of ANP32A in Birds Alters Its Ability to Stimulate RNA Synthesis by Restricted Influenza Polymerase. Cell reports, 24(10), 2581-2588.e4. https://doi.org/10.1016/j.celrep.2018.08.012

PMID: 29942080
Li, J., Griffith, W. P., Davis, I., Shin, I., Wang, J., Li, F., Wang, Y., Wherritt, D. J., & Liu, A. (2018). Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nature chemical biology, 14(9), 853-860. https://doi.org/10.1038/s41589-018-0085-5

PMID: 30012842
Wozniak, K. L., Phelps, W. A., Tembo, M., Lee, M. T., & Carlson, A. E. (2018). The TMEM16A channel mediates the fast polyspermy block in Xenopus laevis. The Journal of general physiology, 150(9), 1249-1259. https://doi.org/10.1085/jgp.201812071

PMID: 30146317
Cajigas, I., Chakraborty, A., Swyter, K. R., Luo, H., Bastidas, M., Nigro, M., Morris, E. R., Chen, S., VanGompel, M., Leib, D., Kohtz, S. J., Martina, M., Koh, S., Ay, F., & Kohtz, J. D. (2018). The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain. Molecular cell, 71(6), 956-972.e9. https://doi.org/10.1016/j.molcel.2018.07.024

PMID: 29691989
Schuelein, R., Spencer, H., Dagley, L. F., Li, P. F., Luo, L., Stow, J. L., Abraham, G., Naderer, T., Gomez-Valero, L., Buchrieser, C., Sugimoto, C., Yamagishi, J., Webb, A. I., Pasricha, S., & Hartland, E. L. (2018). Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL. Cellular microbiology, 20(9), e12852. https://doi.org/10.1111/cmi.12852

PMID: 30206207
Verlekar, D., Wei, S. J., Cho, H., Yang, S., & Kang, M. H. (2018). Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia. Cell death & disease, 9 (9), 925. https://doi.org/10.1038/s41419-018-0964-4

PMID: 30177739
Tiralongo, J., Cooper, O., Litfin, T., Yang, Y., King, R., Zhan, J., Zhao, H., Bovin, N., Day, C. J., & Zhou, Y. (2018). YesU from Bacillus subtilis preferentially binds fucosylated glycans. Scientific reports, 8(1), 13139. https://doi.org/10.1038/s41598-018-31241-8

PMID: 29846129
Sapkota, H., Wasiak, E., Daum, J. R., & Gorbsky, G. J. (2018). Multiple determinants and consequences of cohesion fatigue in mammalian cells. Molecular biology of the cell, 29(15), 1811-1824. https://doi.org/10.1091/mbc.E18-05-0315

PMID: 30148882
Viktorova, E. G., Nchoutmboube, J. A., Ford-Siltz, L. A., Iverson, E., & Belov, G. A. (2018). Phospholipid synthesis fueled by lipid droplets drives the structural development of poliovirus replication organelles. PLoS pathogens, 14(8), e1007280. https://doi.org/10.1371/journal.ppat.1007280

PMID: 29720725
Li, N., Zhang, Y., Sidlauskas, K., Ellis, M., Evans, I., Frankel, P., Lau, J., El-Hassan, T., Guglielmi, L., Broni, J., Richard-Loendt, A., & Brandner, S. (2018). Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades. Oncogene, 37(31), 4313-4333. https://doi.org/10.1038/s41388-018-0277-1

PMID: 30138364
Daer, R., Barrett, C. M., Melendez, E. L., Wu, J., Tekel, S. J., Xu, J., Dennison, B., Muller, R., & Haynes, K. A. (2018). Characterization of diverse homoserine lactone synthases in Escherichia coli. PloS one, 13(8), e0202294. https://doi.org/10.1371/journal.pone.0202294

PMID: 30118678
Tan, Y., Jin, C., Ma, W., Hu, Y., Tanasa, B., Oh, S., Gamliel, A., Ma, Q., Yao, L., Zhang, J., Ohgi, K., Liu, W., Aggarwal, A. K., & Rosenfeld, M. G. (2018). Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program. Molecular cell, 71(4), 526-539.e8. https://doi.org/10.1016/j.molcel.2018.07.039

PMID: 30166540
Huang, W., Peng, Y., Kiselar, J., Zhao, X., Albaqami, A., Mendez, D., Chen, Y., Chakravarthy, S., Gupta, S., Ralston, C., Kao, H. Y., Chance, M. R., & Yang, S. (2018). Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains. Nature communications, 9(1), 3520. https://doi.org/10.1038/s41467-018-06034-2

PMID: 30118682
Penn, B. H., Netter, Z., Johnson, J. R., Von Dollen, J., Jang, G. M., Johnson, T., Ohol, Y. M., Maher, C., Bell, S. L., Geiger, K., Golovkine, G., Du, X., Choi, A., Parry, T., Mohapatra, B. C., Storck, M. D., Band, H., Chen, C., Jäger, S., Shales, M., ? Krogan, N. J. (2018). An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses. Molecular cell, 71(4), 637-648.e5. https://doi.org/10.1016/j.molcel.2018.07.010

PMID: 29880481
Lu, H., Tran, L., Park, Y., Chen, I., Lan, J., Xie, Y., & Semenza, G. L. (2018). Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment. Cancer research, 78(15), 4191-4202. https://doi.org/10.1158/0008-5472.CAN-18-0270

PMID: 29931366
Mintmier, B., McGarry, J. M., Sparacino-Watkins, C. E., Sallmen, J., Fischer-Schrader, K., Magalon, A., McCormick, J. R., Stolz, J. F., Schwarz, G., Bain, D. J., & Basu, P. (2018). Molecular cloning, expression and biochemical characterization of periplasmic nitrate reductase from Campylobacter jejuni. FEMS microbiology letters, 365(16), fny151. https://doi.org/10.1093/femsle/fny151

PMID: 29344929
Sanchez, E., Azcona, L. J., & Paisan-Ruiz, C. (2018). Pla2g6 Deficiency in Zebrafish Leads to Dopaminergic Cell Death, Axonal Degeneration, Increased β-Synuclein Expression, and Defects in Brain Functions and Pathways. Molecular neurobiology, 55(8), 6734-6754. https://doi.org/10.1007/s12035-017-0846-2

PMID: 29752272
van den Bosch, T., Tan, K., Joachimiak, A., & Welte, C. U. (2018). Functional Profiling and Crystal Structures of Isothiocyanate Hydrolases Found in Gut-Associated and Plant-Pathogenic Bacteria. Applied and environmental microbiology, 84(14), e00478-18. https://doi.org/10.1128/AEM.00478-18

PMID: 29871931
Noguchi, K., Dincman, T. A., Dalton, A. C., Howley, B. V., McCall, B. J., Mohanty, B. K., & Howe, P. H. (2018). Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1). The Journal of biological chemistry, 293(29), 11401-11414. https://doi.org/10.1074/jbc.RA118.003616

PMID: 29945888
Huang, Y. H., Klingbeil, O., He, X. Y., Wu, X. S., Arun, G., Lu, B., Somerville, T., Milazzo, J. P., Wilkinson, J. E., Demerdash, O. E., Spector, D. L., Egeblad, M., Shi, J., & Vakoc, C. R. (2018). POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. Genes & development, 32(13-14), 915-928. https://doi.org/10.1101/gad.314815.118

PMID: 29782795
Arias-Mireles, B. H., de Rozieres, C. M., Ly, K., & Joseph, S. (2018). RNA Modulates the Interaction between Influenza A Virus NS1 and Human PABP1. Biochemistry, 57(26), 3590-3598. https://doi.org/10.1021/acs.biochem.8b00218

PMID: 29724813
Roos, A., Dhruv, H. D., Peng, S., Inge, L. J., Tuncali, S., Pineda, M., Millard, N., Mayo, Z., Eschbacher, J. M., Loftus, J. C., Winkles, J. A., & Tran, N. L. (2018). EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival. Molecular cancer research : MCR, 16(7), 1185-1195. https://doi.org/10.1158/1541-7786.MCR-18-0125

PMID: 29990379
Miettinen, H. M., Gripentrog, J. M., Lord, C. I., & Nagy, J. O. (2018). CD177-mediated nanoparticle targeting of human and mouse neutrophils. PloS one, 13(7), e0200444. https://doi.org/10.1371/journal.pone.0200444

PMID: 29460030
Vogel, K. R., Ainslie, G. R., Walters, D. C., McConnell, A., Dhamne, S. C., Rotenberg, A., Roullet, J. B., & Gibson, K. M. (2018). Succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism: an update on pharmacological and enzyme-replacement therapeutic strategies. Journal of inherited metabolic disease, 41(4), 699-708. https://doi.org/10.1007/s10545-018-0153-8

PMID: 29627382
Riegler-Berket, L., Leitmeier, A., Aschauer, P., Dreveny, I., & Oberer, M. (2018). Identification of lipases with activity towards monoacylglycerol by criterion of conserved cap architectures. Biochimica et biophysica acta. Molecular and cell biology of lipids, 1863(7), 679-687. https://doi.org/10.1016/j.bbalip.2018.03.009

PMID: 30045019
Basson, M. D., Wang, Q., Chaturvedi, L. S., More, S., Vomhof-DeKrey, E. E., Al-Marsoummi, S., Sun, K., Kuhn, L. A., Kovalenko, P., & Kiupel, M. (2018). Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(3), 1274-1290. https://doi.org/10.1159/000492019

PMID: 30082509
Goblirsch, B. R., Arachea, B. T., Councell, D. J., & Wiener, M. C. (2018). Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24. Acta crystallographica. Section D, Structural biology, 74(Pt 8), 739-747. https://doi.org/10.1107/S2059798318003431

PMID: 29767960
Odokonyero, D., McMillan, A. W., Ramagopal, U. A., Toro, R., Truong, D. P., Zhu, M., Lopez, M. S., Somiari, B., Herman, M., Aziz, A., Bonanno, J. B., Hull, K. G., Burley, S. K., Romo, D., Almo, S. C., & Glasner, M. E. (2018). Comparison of Alicyclobacillus acidocaldarius o-Succinylbenzoate Synthase to Its Promiscuous N-Succinylamino Acid Racemase/ o-Succinylbenzoate Synthase Relatives. Biochemistry, 57(26), 3676-3689. https://doi.org/10.1021/acs.biochem.8b00088

PMID: 30018401
Wang, J., Molday, L. L., Hii, T., Coleman, J. A., Wen, T., Andersen, J. P., & Molday, R. S. (2018). Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues. Scientific reports, 8(1), 10795. https://doi.org/10.1038/s41598-018-29108-z

29869361
Ritt, M., & Sivaramakrishnan, S. (2018). Engaging myosin VI tunes motility, morphology and identity in endocytosis. Traffic (Copenhagen, Denmark), 10.1111/tra.12583. Advance online publication. https://doi.org/10.1111/tra.12583

PMID: 29703752
Davis, I., Yang, Y., Wherritt, D., & Liu, A. (2018). Reassignment of the human aldehyde dehydrogenase ALDH8A1 (ALDH12) to the kynurenine pathway in tryptophan catabolism. The Journal of biological chemistry, 293(25), 9594-9603. https://doi.org/10.1074/jbc.RA118.003320

PMID: 29604149
Mills, C. L., Garg, R., Lee, J. S., Tian, L., Suciu, A., Cooperman, G. D., Beuning, P. J., & Ondrechen, M. J. (2018). Functional classification of protein structures by local structure matching in graph representation. Protein science : a publication of the Protein Society, 27(6), 1125-1135. https://doi.org/10.1002/pro.3416

PMID: 29874572
Pinarbasi, E. S., Karamyshev, A. L., Tikhonova, E. B., Wu, I. H., Hudson, H., & Thomas, P. J. (2018). Pathogenic Signal Sequence Mutations in Progranulin Disrupt SRP Interactions Required for mRNA Stability. Cell reports, 23(10), 2844-2851. https://doi.org/10.1016/j.celrep.2018.05.003

PMID: 29741624
Esquivel-Elizondo, S., Maldonado, J., & Krajmalnik-Brown, R. (2018). Anaerobic carbon monoxide metabolism by Pleomorphomonas carboxyditropha sp. nov., a new mesophilic hydrogenogenic carboxydotroph. FEMS microbiology ecology, 94(6), 10.1093/femsec/fiy056. https://doi.org/10.1093/femsec/fiy056

PMID: 30046229
Xu, H., Bai, X., Yu, S., Liu, Q., Pestell, R. G., & Wu, K. (2018). MAT1 correlates with molecular subtypes and predicts poor survival in breast cancer. Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 30(3), 351-363. https://doi.org/10.21147/j.issn.1000-9604.2018.03.07

PMID: 29779826
White, P. J., McGarrah, R. W., Grimsrud, P. A., Tso, S. C., Yang, W. H., Haldeman, J. M., Grenier-Larouche, T., An, J., Lapworth, A. L., Astapova, I., Hannou, S. A., George, T., Arlotto, M., Olson, L. B., Lai, M., Zhang, G. F., Ilkayeva, O., Herman, M. A., Wynn, R. M., Chuang, D. T., ? Newgard, C. B. (2018). The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase. Cell metabolism, 27(6), 1281-1293.e7. https://doi.org/10.1016/j.cmet.2018.04.015

PMID: 29635000
Cho, E. B., Yoo, W., Yoon, S. K., & Yoon, J. B. (2018). β-dystroglycan is regulated by a balance between WWP1-mediated degradation and protection from WWP1 by dystrophin and utrophin. Biochimica et biophysica acta. Molecular basis of disease, 1864(6 Pt A), 2199-2213. https://doi.org/10.1016/j.bbadis.2018.04.001

PMID: 29932900
Dronamraju, R., Hepperla, A. J., Shibata, Y., Adams, A. T., Magnuson, T., Davis, I. J., & Strahl, B. D. (2018). Spt6 Association with RNA Polymerase II Directs mRNA Turnover During Transcription. Molecular cell, 70(6), 1054-1066.e4. https://doi.org/10.1016/j.molcel.2018.05.020

PMID: 29463842
Bagati, A., Bianchi-Smiraglia, A., Moparthy, S., Kolesnikova, K., Fink, E. E., Kolesnikova, M., Roll, M. V., Jowdy, P., Wolff, D. W., Polechetti, A., Yun, D. H., Lipchick, B. C., Paul, L. M., Wrazen, B., Moparthy, K., Mudambi, S., Morozevich, G. E., Georgieva, S. G., Wang, J., Shafirstein, G., ... Nikiforov, M. A. (2018). FOXQ1 controls the induced differentiation of melanocytic cells. Cell death and differentiation, 25(6), 1040-1049. https://doi.org/10.1038/s41418-018-0066-y

PMID: 29928062
Navas, T., Pfister, T. D., Colantonio, S., Aziz, A., Dieckman, L., Saul, R. G., Kaczmarczyk, J., Borgel, S., Alcoser, S. Y., Hollingshead, M. G., Lee, Y. H., Bottaro, D. P., Hiltke, T., Whiteley, G., Takebe, N., Kinders, R. J., Parchment, R. E., Tomaszewski, J. E., & Doroshow, J. H. (2018). Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells. PloS one, 13(6), e0199361. https://doi.org/10.1371/journal.pone.0199361

PMID: 29802247
Diplas, B. H., He, X., Brosnan-Cashman, J. A., Liu, H., Chen, L. H., Wang, Z., Moure, C. J., Killela, P. J., Loriaux, D. B., Lipp, E. S., Greer, P. K., Yang, R., Rizzo, A. J., Rodriguez, F. J., Friedman, A. H., Friedman, H. S., Wang, S., He, Y., McLendon, R. E., Bigner, D. D., ? Yan, H. (2018). The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma. Nature communications, 9(1), 2087. https://doi.org/10.1038/s41467-018-04448-6

PMID: 29648791
Li, B. X., Chen, J., Chao, B., David, L. L., & Xiao, X. (2018). Anticancer Pyrroloquinazoline LBL1 Targets Nuclear Lamins. ACS chemical biology, 13(5), 1380-1387. https://doi.org/10.1021/acschembio.8b00266

PMID: 29514927
Huang, E. Y., To, M., Tran, E., Dionisio, L., Cho, H. J., Baney, K., Pataki, C. I., & Olzmann, J. A. (2018). A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates. Molecular biology of the cell, 29(9), 1021-1030. https://doi.org/10.1091/mbc.E17-08-0514

PMID: 29718972
Morales, Y., Olsen, K. J., Bulcher, J. M., & Johnson, S. J. (2018). Structure of frequency-interacting RNA helicase from Neurospora crassa reveals high flexibility in a domain critical for circadian rhythm and RNA surveillance. PloS one, 13(5), e0196642. https://doi.org/10.1371/journal.pone.0196642

PMID: 29765358
Vinuesa, P., Ochoa-Sánchez, L. E., & Contreras-Moreira, B. (2018). GET_PHYLOMARKERS, a Software Package to Select Optimal Orthologous Clusters for Phylogenomics and Inferring Pan-Genome Phylogenies, Used for a Critical Geno-Taxonomic Revision of the Genus Stenotrophomonas. Frontiers in microbiology, 9, 771. https://doi.org/10.3389/fmicb.2018.00771

PMID: 29752409
Stopschinski, B. E., Holmes, B. B., Miller, G. M., Manon, V. A., Vaquer-Alicea, J., Prueitt, W. L., Hsieh-Wilson, L. C., & Diamond, M. I. (2018). Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau versus α-synuclein and β-amyloid aggregates. The Journal of biological chemistry, 293(27), 10826-10840. https://doi.org/10.1074/jbc.RA117.000378

PMID: 29307802
Radha, R., Arumugam, N., & Gummadi, S. N. (2018). Glutaminase free l-asparaginase from Vibrio cholerae: Heterologous expression, purification and biochemical characterization. International journal of biological macromolecules, 111, 129-138. https://doi.org/10.1016/j.ijbiomac.2017.12.165

PMID: 29930736
Heidari, P., Kunawudhi, A., Martinez-Quintanilla, J., Szretter, A., Shah, K., & Mahmood, U. (2018). Somatostatin receptor type 2 as a radiotheranostic PET reporter gene for oncologic interventions. Theranostics, 8(12), 3380-3391. https://doi.org/10.7150/thno.24017

PMID: 29728077
Naik, A., Al-Yahyaee, A., Abdullah, N., Sam, J. E., Al-Zeheimi, N., Yaish, M. W., & Adham, S. A. (2018). Neuropilin-1 promotes the oncogenic Tenascin-C/integrin β3 pathway and modulates chemoresistance in breast cancer cells. BMC cancer, 18(1), 533. https://doi.org/10.1186/s12885-018-4446-y

PMID: 29760474
Trastoy, B., Klontz, E., Orwenyo, J., Marina, A., Wang, L. X., Sundberg, E. J., & Guerin, M. E. (2018). Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S. Nature communications, 9(1), 1874. https://doi.org/10.1038/s41467-018-04300-x

PMID: 29531365
Knowlton, J. J., Fernández de Castro, I., Ashbrook, A. W., Gestaut, D. R., Zamora, P. F., Bauer, J. A., Forrest, J. C., Frydman, J., Risco, C., & Dermody, T. S. (2018). The TRiC chaperonin controls reovirus replication through outer-capsid folding. Nature microbiology, 3(4), 481-493. https://doi.org/10.1038/s41564-018-0122-x

PMID: 29662124
Ding, S., Diep, J., Feng, N., Ren, L., Li, B., Ooi, Y. S., Wang, X., Brulois, K. F., Yasukawa, L. L., Li, X., Kuo, C. J., Solomon, D. A., Carette, J. E., & Greenberg, H. B. (2018). STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection. Nature communications, 9(1), 1485. https://doi.org/10.1038/s41467-018-03782-z

PMID: 29670592
Zhang, X. Y., Zhao, T. Y., Li, Y. Y., Xiang, H. Y., Dong, S. W., Zhang, Z. Y., Wang, Y., Li, D. W., Yu, J. L., & Han, C. G. (2018). The Conserved Proline18 in the Polerovirus P3a Is Important for Brassica Yellows Virus Systemic Infection. Frontiers in microbiology, 9, 613. https://doi.org/10.3389/fmicb.2018.00613

PMID: 29691457
Heitmeier, M. R., Payne, M. A., Weinheimer, C., Kovacs, A., Hresko, R. C., Jay, P. Y., & Hruz, P. W. (2018). Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia. Scientific reports, 8(1), 6475. https://doi.org/10.1038/s41598-018-24867-1

PMID: 29398709
Rauf, F., Festa, F., Park, J. G., Magee, M., Eaton, S., Rinaldi, C., Betanzos, C. M., Gonzalez-Malerva, L., & LaBaer, J. (2018). Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner. Oncogene, 37(17), 2237-2250. https://doi.org/10.1038/s41388-017-0079-x

PMID: 29668703
Gunaratne, G. S., Yahya, N. A., Dosa, P. I., & Marchant, J. S. (2018). Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers. PLoS neglected tropical diseases, 12(4), e0006420. https://doi.org/10.1371/journal.pntd.0006420

PMID: 29337190
Marco, P., Kozuleva, M., Eilenberg, H., Mazor, Y., Gimeson, P., Kanygin, A., Redding, K., Weiner, I., & Yacoby, I. (2018). Binding of ferredoxin to algal photosystem I involves a single binding site and is composed of two thermodynamically distinct events. Biochimica et biophysica acta. Bioenergetics, 1859(4), 234-243. https://doi.org/10.1016/j.bbabio.2018.01.001

PMID: 28924186
Zhou, Y., Dong, F., Lanz, T. A., Reinhart, V., Li, M., Liu, L., Zou, J., Xi, H. S., & Mao, Y. (2018). Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment. Molecular psychiatry, 23(4), 952-962. https://doi.org/10.1038/mp.2017.166

PMID: 29715548
Park, J. W., Lee, C. M., Cheng, J. S., & Morgan, E. T. (2018). Posttranslational regulation of CYP2J2 by nitric oxide. Free radical biology & medicine, 121, 149-156. https://doi.org/10.1016/j.freeradbiomed.2018.04.576

PMID: 29531224
Lin, C. C., Kitagawa, M., Tang, X., Hou, M. H., Wu, J., Qu, D. C., Srinivas, V., Liu, X., Thompson, J. W., Mathey-Prevot, B., Yao, T. P., Lee, S. H., & Chi, J. T. (2018). CoA synthase regulates mitotic fidelity via CBP-mediated acetylation. Nature communications, 9(1), 1039. https://doi.org/10.1038/s41467-018-03422-6

PMID: 29337693
Palanirajan, S. K., Sivagnanam, U., Murugan, S., & Gummadi, S. N. (2018). In vitro reconstitution and biochemical characterization of human phospholipid scramblase 3: phospholipid specificity and metal ion binding studies. Biological chemistry, 399(4), 361-374. https://doi.org/10.1515/hsz-2017-0309

PMID: 29497057
Bai, M., Vozdek, R., Hnizda, A., Jiang, C., Wang, B., Kuchar, L., Li, T., Zhang, Y., Wood, C., Feng, L., Dang, Y., & Ma, D. K. (2018). Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection. Nature communications, 9(1), 897. https://doi.org/10.1038/s41467-018-03355-0

PMID: 29266787
Yamagishi, Y., & Abe, H. (2018). Actin assembly mediated by a nucleation promoting factor WASH is involved in MTOC-TMA formation during Xenopus oocyte maturation. Cytoskeleton (Hoboken, N.J.), 75(3), 131-143. https://doi.org/10.1002/cm.21428

PMID: 29249802
Howley, B. V., Link, L. A., Grelet, S., El-Sabban, M., & Howe, P. H. (2018). A CREB3-regulated ER-Golgi trafficking signature promotes metastatic progression in breast cancer. Oncogene, 37(10), 1308-1325. https://doi.org/10.1038/s41388-017-0023-0

PMID: 29634317
Xiong, J., Pecchi, V. G., Qui, M., Ivanov, A. A., Mo, X., Niu, Q., Chen, X., Fu, H., & Du, Y. (2018). Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction. Assay and drug development technologies, 16(2), 96-106. https://doi.org/10.1089/adt.2017.835

PMID: 29505581
Sørensen, D. M., Holemans, T., van Veen, S., Martin, S., Arslan, T., Haagendahl, I. W., Holen, H. W., Hamouda, N. N., Eggermont, J., Palmgren, M., & Vangheluwe, P. (2018). Parkinson disease related ATP13A2 evolved early in animal evolution. PloS one, 13(3), e0193228. https://doi.org/10.1371/journal.pone.0193228

PMID: 29092903
Wiley, S. Z., Sriram, K., Liang, W., Chang, S. E., French, R., McCann, T., Sicklick, J., Nishihara, H., Lowy, A. M., & Insel, P. A. (2018). GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(3), 1170-1183. https://doi.org/10.1096/fj.201700834R

29580262
Paz, H., Joo, E. J., Chou, C. H., Fei, F., Mayo, K. H., Abdel-Azim, H., Ghazarian, H., Groffen, J., & Heisterkamp, N. (2018). Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008. Journal of experimental & clinical cancer research : CR, 37(1), 67. https://doi.org/10.1186/s13046-018-0721-7

PMID: 29228333
Hartill, V. L., van de Hoek, G., Patel, M. P., Little, R., Watson, C. M., Berry, I. R., Shoemark, A., Abdelmottaleb, D., Parkes, E., Bacchelli, C., Szymanska, K., Knoers, N. V., Scambler, P. J., Ueffing, M., Boldt, K., Yates, R., Winyard, P. J., Adler, B., Moya, E., Hattingh, L., ? Johnson, C. A. (2018). DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport. Human molecular genetics, 27(3), 529-545. https://doi.org/10.1093/hmg/ddx422

PMID: 29212708
Ha, B. H., & Boggon, T. J. (2018). The crystal structure of pseudokinase PEAK1 (Sugen kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization. The Journal of biological chemistry, 293(5), 1642-1650. https://doi.org/10.1074/jbc.RA117.000751

PMID: 29200207
Hill, Z. B., Martinko, A. J., Nguyen, D. P., & Wells, J. A. (2018). Human antibody-based chemically induced dimerizers for cell therapeutic applications. Nature chemical biology, 14(2), 112-117. https://doi.org/10.1038/nchembio.2529

PMID: 28705764
Hammond, J. A., Zhou, L., Lamichhane, R., Chu, H. Y., Millar, D. P., Gerace, L., & Williamson, J. R. (2018). A Survey of DDX21 Activity During Rev/RRE Complex Formation. Journal of molecular biology, 430(4), 537-553. https://doi.org/10.1016/j.jmb.2017.06.023

PMID: 29426933
Allu, P. K., Boggula, Y., Karri, S., Marada, A., Krishnamoorthy, T., & Sepuri, N. (2018). A conserved R type Methionine Sulfoxide Reductase reverses oxidized GrpEL1/Mge1 to regulate Hsp70 chaperone cycle. Scientific reports, 8(1), 2716. https://doi.org/10.1038/s41598-018-21083-9

PMID: 29288958
Nidetz, N. F., Gallagher, T. M., & Wiethoff, C. M. (2018). Inhibition of type I interferon responses by adenovirus serotype-dependent Gas6 binding. Virology, 515, 150-157. https://doi.org/10.1016/j.virol.2017.12.016

PMID: 29515592
Loes, A. N., Bridgham, J. T., & Harms, M. J. (2018). Coevolution of the Toll-Like Receptor 4 Complex with Calgranulins and Lipopolysaccharide. Frontiers in immunology, 9, 304. https://doi.org/10.3389/fimmu.2018.00304

PMID: 29432141
Munro, A. W., McLean, K. J., Grant, J. L., & Makris, T. M. (2018). Structure and function of the cytochrome P450 peroxygenase enzymes. Biochemical Society transactions, 46(1), 183-196. https://doi.org/10.1042/BST20170218

PMID: 29309642
Ming, Q., Roske, Y., Schuetz, A., Walentin, K., Ibraimi, I., Schmidt-Ott, K. M., & Heinemann, U. (2018). Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family. Nucleic acids research, 46(4), 2082-2095. https://doi.org/10.1093/nar/gkx1299

PMID: 29194006
Gavya, S. L., Arora, N., & Ghosh, S. S. (2018). Retention of functional characteristics of glutathione-S-transferase and lactate dehydrogenase-A in fusion protein. Preparative biochemistry & biotechnology, 48(2), 128-135. https://doi.org/10.1080/10826068.2017.1405022

PMID: 29473022
Chuang, Y. M., Pinn, M. L., Karakousis, P. C., & Hung, C. F. (2018). Intranasal Immunization with DnaK Protein Induces Protective Mucosal Immunity against Tuberculosis in CD4-Depleted Mice. Frontiers in cellular and infection microbiology, 8, 31. https://doi.org/10.3389/fcimb.2018.00031

PMID: 29531845
Chang, X., & Hou, Y. (2018). Expression of RecA and cell-penetrating peptide (CPP) fusion protein in bacteria and in mammalian cells. International journal of biochemistry and molecular biology, 9(1), 1-10.

PMID: 29428737
Emanuelle, S., Doblin, M. S., Gooley, P. R., & Gentry, M. S. (2018). The UBA domain of SnRK1 promotes activation and maintains catalytic activity. Biochemical and biophysical research communications, 497(1), 127-132. https://doi.org/10.1016/j.bbrc.2018.02.039

PMID: 29516482
Hansen, D. T., Craciunescu, F. M., Fromme, P., Johnston, S. A., & Sykes, K. F. (2018). Generation of High-Specificity Antibodies against Membrane Proteins Using DNA-Gold Micronanoplexes for Gene Gun Immunization. Current protocols in protein science, 91, 29.20.1-29.20.22. https://doi.org/10.1002/cpps.50

PMID: 29474160
Conway, T. P., Daniels, K. J., Park, Y. N., & Soll, D. R. (2018). Generating a Battery of Monoclonal Antibodies Against Firefly Luciferase for Dot Blot Analysis, Western Blot Analysis, and Immunostaining of Cells in Culture and Paraffin Sections. Monoclonal antibodies in immunodiagnosis and immunotherapy, 37(1), 45-51. https://doi.org/10.1089/mab.2017.0057

PMID: 29117939
Ding, Z., Roos, A., Kloss, J., Dhruv, H., Peng, S., Pirrotte, P., Eschbacher, J. M., Tran, N. L., & Loftus, J. C. (2018). A Novel Signaling Complex between TROY and EGFR Mediates Glioblastoma Cell Invasion. Molecular cancer research : MCR, 16(2), 322-332. https://doi.org/10.1158/1541-7786.MCR-17-0454

PMID: 29124284
Kumar, R., Raman, R., Kotapalli, V., Gowrishankar, S., Pyne, S., Pollack, J. R., & Bashyam, M. D. (2018). Ca2+/nuclear factor of activated T cells signaling is enriched in early-onset rectal tumors devoid of canonical Wnt activation. Journal of molecular medicine (Berlin, Germany), 96(2), 135-146. https://doi.org/10.1007/s00109-017-1607-4

PMID: 29227283
Tamiya, H., Kim, H., Klymenko, O., Kim, H., Feng, Y., Zhang, T., Han, J. Y., Murao, A., Snipas, S. J., Jilaveanu, L., Brown, K., Kluger, H., Zhang, H., Iwai, K., & Ronai, Z. A. (2018). SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth. The Journal of clinical investigation, 128(1), 517-530. https://doi.org/10.1172/JCI95410

PMID: 29382735
Rinkenberger, N., & Schoggins, J. W. (2018). Mucolipin-2 Cation Channel Increases Trafficking Efficiency of Endocytosed Viruses. mBio, 9(1), e02314-17. https://doi.org/10.1128/mBio.02314-17

PMID: 29357389
Lv, D. W., Zhang, K., & Li, R. (2018). Interferon regulatory factor 8 regulates caspase-1 expression to facilitate Epstein-Barr virus reactivation in response to B cell receptor stimulation and chemical induction. PLoS pathogens, 14(1), e1006868. https://doi.org/10.1371/journal.ppat.1006868

PMID: 29316436
Gwinn, D. M., Lee, A. G., Briones-Martin-Del-Campo, M., Conn, C. S., Simpson, D. R., Scott, A. I., Le, A., Cowan, T. M., Ruggero, D., & Sweet-Cordero, E. A. (2018). Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase. Cancer cell, 33(1), 91-107.e6. https://doi.org/10.1016/j.ccell.2017.12.003

PMID: 29343704
Bachman, A. B., Keramisanou, D., Xu, W., Beebe, K., Moses, M. A., Vasantha Kumar, M. V., Gray, G., Noor, R. E., van der Vaart, A., Neckers, L., & Gelis, I. (2018). Phosphorylation induced cochaperone unfolding promotes kinase recruitment and client class-specific Hsp90 phosphorylation. Nature communications, 9(1), 265. https://doi.org/10.1038/s41467-017-02711-w

PMID: 29186613
Agarwal, S., & Cho, T. Y. (2018). Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter. Nucleic acids research, 46(2), 929-941. https://doi.org/10.1093/nar/gkx1183

PMID: 29338718
Ballister, E. R., Rodgers, J., Martial, F., & Lucas, R. J. (2018). A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling. BMC biology, 16(1), 10. https://doi.org/10.1186/s12915-017-0475-2

PMID: 29125663
Gandomkar, S., Dennig, A., Dordic, A., Hammerer, L., Pickl, M., Haas, T., Hall, M., & Faber, K. (2018). Biocatalytic Oxidative Cascade for the Conversion of Fatty Acids into α-Ketoacids via Internal H2 O2 Recycling. Angewandte Chemie (International ed. in English), 57(2), 427-430. https://doi.org/10.1002/anie.201710227

PMID: 29198941
Man, J., Yu, X., Huang, H., Zhou, W., Xiang, C., Huang, H., Miele, L., Liu, Z., Bebek, G., Bao, S., & Yu, J. S. (2018). Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells. Cell stem cell, 22(1), 104-118.e6. https://doi.org/10.1016/j.stem.2017.10.005

PMID: 29104065
O'Banion, C. P., Priestman, M. A., Hughes, R. M., Herring, L. E., Capuzzi, S. J., & Lawrence, D. S. (2018). Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase. Cell chemical biology, 25(1), 100-109.e8. https://doi.org/10.1016/j.chembiol.2017.09.011

PMID: 29042395
Wang, Z., Wu, D., Ng, C. F., Teoh, J. Y., Yu, S., Wang, Y., & Chan, F. L. (2018). Nuclear receptor profiling in prostatospheroids and castration-resistant prostate cancer. Endocrine-related cancer, 25(1), 35-50. https://doi.org/10.1530/ERC-17-0280

PMID: 29372903
Mank, N. J., Pote, S., Majorek, K. A., Arnette, A. K., Klapper, V. G., Hurlburt, B. K., & Chruszcz, M. (2018). Structure of aspartate β-semialdehyde dehydrogenase from Francisella tularensis. Acta crystallographica. Section F, Structural biology communications, 74(Pt 1), 14-22. https://doi.org/10.1107/S2053230X17017241

PMID: 29249655
Jin, L., Chun, J., Pan, C., Kumar, A., Zhang, G., Ha, Y., Li, D., Alesi, G. N., Kang, Y., Zhou, L., Yu, W. M., Magliocca, K. R., Khuri, F. R., Qu, C. K., Metallo, C., Owonikoko, T. K., & Kang, S. (2018). The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer. Molecular cell, 69(1), 87-99.e7. https://doi.org/10.1016/j.molcel.2017.11.025

PMID: 29433439
Yu, X., Noll, R. R., Romero Duenas, B. P., Allgood, S. C., Barker, K., Caplan, J. L., Machner, M. P., LaBaer, J., Qiu, J., & Neunuebel, M. R. (2018). Legionella effector AnkX interacts with host nuclear protein PLEKHN1. BMC microbiology, 18(1), 5. https://doi.org/10.1186/s12866-017-1147-7