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Human Plasmid Collections

90/90 Human ORFeome V 3 (Gateway Entry Vectors) - Complete Collection
90/90 Human ORFeome V 3 (Gateway Entry Vectors) - Membrane Secreted Proteins Subcollection
90/90 Human ORFeome V 3 (Gateway Entry Vectors) - Other Subcollection
90/90 Human ORFeome V 3 (Gateway Entry Vectors) - Transcription Factor Subcollection
BC1000: 1000 human breast cancer-associated genes (pDNR-Dual Gateway Entry Vector, C-terminal tag only)
BC1000: 1000 human breast cancer-associated genes (pDNR-Dual Gateway Entry Vector, untagged only)
BC1000: 1000 human breast cancer-associated genes (pDNR-Dual Gateway Entry Vector; complete set)
Epigenetic Factors and Epigene Histones
Human 3`UTRome v1 collection (Gateway Entry vector)
Human ORFeome V8.1 collection (Gateway Entry vector)
Human expression clone collection (pLDNT7_nFLAG; cell-free expression vector with Flag tag)
Human expression clone collection Complete (pLDNT7_nFLAG, pANT7_cGST; cell-free expression vectors)
Human hORFeome V8.1 Lentiviral collection
Human kinase collection (pDNR-Dual Gateway Entry Vector; complete set)
Human kinase collection (pDNR-Dual Gateway Entry vector; C-terminal tag only)
Human kinase collection (pJP1520 puromycin resistant retroviral vector)
Human kinase collection (pJP1563 blasticidin resistant retroviral vector)


Other Species Plasmid Collections

Arabidopsis thaliana Collection V 1 (Gateway Entry Vectors)
BASIL starter pack V1
FlyBi Drosophila ORFeome vFB5.52
Saccharomyces cerevisiae (yeast) ORF collection (ZM552 expression vector)
Saccharomyces cerevisiae (yeast) ORF collection (pBY011 expression vector)
Saccharomyces cerevisiae (yeast) whole genome ORF collection (pDONR201 or pDONR221 Gateway Entry vectors)
Thermatoga Maritima Plasmid collection (in pMH bacterial expression vectors)
Xenopus ORFeome Collection


Pathogen Genome Collections

Bacillus anthracis whole genome ORF collection (cell-free expression vector)
Bacillus anthracis whole genome ORF collection (pDONR221 Gateway Entry vector)
Francisella tularensis whole genome ORF collection (E. coli expression vector)
Francisella tularensis whole genome ORF collection (pDONR221 Gateway Entry Vector)
Francisella tularensis whole genome ORF collection (yeast expression vector with tags)
Pseudomonas aeruginosa whole genome ORF collection (pDONR201 Gateway Entry vector)
Vaccinia virus ORF collection (cell free expression vector)
Vibrio cholerae ORF collection (cell-free expression vector)
Vibrio cholerae whole genome ORF collection (pDONR221 Gateway Entry vector)
Viral Collection pANT7-cGST V1
Viral Donor Subset
Viral Proteome Collection - pANT7 cGST Expression Vector
Yersinia pestis whole genome ORF collection (pDONR221 vector Gateway Entry Vector)
Yersinia pseudotuberculosis whole genome ORF collection (pDONR221 Gateway Entry vector)

Biological Annotation

Signalling         Nuclear         Extracellular         Other        

Signalling

14_3_3 4.1m ADF ANK ARF
ARM ArfGap B41 B561 BAG
BH4 BIR BTK B_lectin C1
C2 CARD CASc CH CNH
CULLIN CYCc Calx_beta CheW Cyt-b5
DAGKa DAGKc DAX DEATH DED
DEP DSPc DYNc EAL EFh
EH ENTH FBOX FCH FF
FH2 FHA FIST FYVE GAF
GAS2 GED GGDEF GGL GRAM
GS G_alpha GoLoco GuKc HAMP
HATPase_c HECTc HPT HisKA Hr1
ILWEQ IPPc IQ ITAM KISc
L27 LIM LMWPc MA MIR
MYSc MeTrc MyTH4 PAC PAS
PASTA PBD PDZ PH PI3K_C2
PI3K_p85B PI3K_rbd PI3Ka PI3Kc PIPKc
PLAc PLCXc PLCYc PLDc PP2Ac
PP2Cc PTB PTBI PTPc PTPc_motif
PX PXA RA RAB RAN
RAS RBD REC RGS RHO
RHOD RIIa RING RIO RanBD
RasGAP RasGEF RasGEFN RhoGAP RhoGEF
SAM SAR SEC14 SH2 SH3
SOCS SPEC SPRY START STAT_int
S_TK_X S_TKc Sec7 TBC TIR
TRASH TarH TyrKc UBA UBCc
UBQ UBX VHP VHS VPS9
WD40 WH1 WH2 WW ZU5
ZnF_A20 ZnF_AN1 ZnF_RBZ ZnF_UBP ZnF_ZZ
acidPPc cNMP t_SNARE

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Nuclear

35EXOc 53EXOc A1pp ADEAMc ANTAR
AP2 AP2Ec APC2 ARID AT_hook
AWS AXH AlkA_N AraC_E_bind B3
BAF BAH BASIC BBC BBOX
BCL BEN BHD_1 BHD_2 BHD_3
BING4CT BOP1NT BP28CT BRCT BRIGHT
BRK BRLZ BROMO BSD BTP
Bro-N Brr6_like_C_C C1_4 CAT_RBD CBF
CDT1 CENPB CG-1 CHK CHROMO
CKS CPDc CPSF73-100_C CRM1_C CSP
CTD CUT CarD_TRCF Cdc6_C Cir_N
Copper-fist Cu_FIST D5_N DDE_Tnp_IS1595 DDT
DEXDc DM DMAP_binding DP DSHCT
DSRM DSX_dimer DUF1087 DUF1693 DUF1744
DWA DWB DZF ENDO3c ERCC4
ETS EXOIII Elp3 Endonuclease_NS FBD
FCD FES FH FYRC FYRN
Fapy_DNA_glyco Ftsk_gamma Fungal_trans GIYc G_patch
H15 H2A H2B H3 H4
HALZ HDAC_interact HELICc HLH HMG
HMG17 HNHc HNS HOLI HOX
HRDC HSA HSF HTH_ARAC HTH_ARSR
HTH_ASNC HTH_CRP HTH_DEOR HTH_DTXR HTH_GNTR
HTH_ICLR HTH_LACI HTH_LUXR HTH_MARR HTH_MERR
HTH_XRE HhH1 HhH2 IBN_N IENR1
IENR2 IPT IRF IRO JmjC
JmjN KH KOW KRAB Ku78
LEM LIGANc LNS2 LytTR MA3
MADF MADS MBD MBT MCM
MUTSac MUTSd MutH MutL_C NEUZ
NGN NOSIC NurA ORANGE PAX
PAZ PHD POL3Bc POLAc POLBc
POLIIIAc POLXc POP4 POU POX
PRE_C2HC PRY PSP PUA PUG
PUR ParB Piwi Plus3 PostSET
PreSET PriCT_1 Prim-Pol RIBOc RPOL4c
RPOL8c RPOL9 RPOLA_N RPOLCX RPOLD
RPR RQC RRM RWD Resolvase
Rho_N S4 SAND SANT SAP
SCAN SET SFM SMC_hinge SMR
SPK SPT2 SRA STE Skp1
Sm SpoVT_AbrB TAF TBOX TDU
TEA TFIIE TFS2M TFS2N THAP
TIFY TOP1Ac TOP1Bc TOP2c TOP4c
TOPEUc TOPRIM TRCF Telo_bind Telomerase_RBD
Trans_reg_C UDG UME UTRA Ubox
XPGI XPGN YL1_C YccV-like YqgFc
Zalpha ZnF_BED ZnF_C2C2 ZnF_C2H2 ZnF_C2HC
ZnF_C3H1 ZnF_C4 ZnF_CHCC ZnF_DBF ZnF_GATA
ZnF_NFX ZnF_PMZ ZnF_Rad18 ZnF_U1 eIF5C
zf-AD

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Extracellular

A4_EXTRA AAI ACR AIP3 ALBUMIN
AMA-1 AMOP ANATO APPLE A_amylase_inhib
Aamy Aamy_C Aerolysin Agglutinin Amb_V_allergen
Amb_all Ami_2 Ami_3 Asparaginase Autotransporter
BID_1 BID_2 BON BPI1 BPI2
Bet_v_1 BowB C1Q C345C C4
C6 CA CADG CALCITONIN CASH
CBD_II CBD_IV CCP CFEM CHASE
CHASE2 CHRD CLECT CLIP CLa
CLb CNX COLFI COLIPASE CRF
CSF2 CT CUB CW CY
Cache_2 ChW ChtBD1 ChtBD2 ChtBD3
Col_cuticle_N Connexin_CCC Cutinase CysPc DEFSN
DISIN DM4_12 DM6 DNaseIc DSL
DoH EGF EGF_CA EGF_Lam END
EPEND EPH_lbd Excalibur FA58C FAS1
FBG FGF FIMAC FN1 FN2
FN3 FOLN FRI FTP FU
Flu_M1_C G2F GA GASTRIN GEL
GHA GHB GLA GLECT GLUCA
GPS GRAN Galanin Glyco_10 Glyco_18
Glyco_25 Glyco_32 HX HYDRO Haemagg_act
HintC HintN HormR IB IFabd
IG IGc1 IGc2 IGv IL1
IL10 IL2 IL4_13 IL6 IL7
INB IlGF Inhibitor_I29 Int_alpha JHBP
Jacalin KAZAL KR KU Kelch
Knot1 LCCL LDLa LIF_OSM LINK
LPD_N LRRCT LRRNT LRR_BAC LRR_CC
LRR_RI LRR_SD22 LRR_TYP LU LY
LYZ1 LYZ2 LamB LamG LamGL
LamNT LysM MACPF MAM MANEC
MATH MD MHC_II_alpha MHC_II_beta ML
NAT_PEP NEAT NGF NH NIDO
NL NMU NRF NTR NUC
OLF OSTEO P4Hc PA2c PAH
PAN_AP PBP5_C PBPb PBPe PD
PDGF PGA_cap PGRP PKD PLP
PQQ PRP PSA PSI_domain PTH
PTI PTN PTX PbH1 Pept_C1
PhBP RICIN RNAse_Pc SAA SAPA
SCP SCPU SCY SEA SEL1
SERPIN SF_P SH3b SO SR
STI STN SapB Sema ShKT
TECPR TGFB THN TK TNF
TNFR TR_FER TR_THY TSP1 TSPN
TSPc TY Tryp_SPc UTG VIT
VPS10 VWA VWC VWD WAP
WIF WNT1 WR1 WSC X8
XTALbg ZP ZnMc Zn_dep_PLPC Zn_pept
btg1 fCBD s48_45

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Other

AAA AAA_PrkA AARP2CN ACTIN AD
ADSL_C AFOR_N AGTRAP AHS1 AHS2
AICARFT_IMPCHas AIRC AKAP_110 ALAD AMPKBI
AMP_N ANX ASCH Ad_cyc_g-alpha Adenylsucc_synt
AdoHcyase AdoHcyase_NAD Agenet Agouti AgrB
AgrD Agro_virD5 Aha1_N AlaDh_PNT_C AlaDh_PNT_N
Ala_racemase_C AlcB Ald_Xan_dh_C Aldolase_II Alpha-L-AF_C
Alpha-amyl_C2 Alpha-mann_mid Alpha_L_fucos Alpha_TIF Alpha_adaptinC2
Alpha_kinase Amelin Amelogenin Arfaptin Arg_tRNA_synt_N
Arrestin_C B12-binding_2 B2-adapt-app_C B3_4 B5
BACK BAR BATS BCS1_N BHL
BLUF BMC BRICHOS BRO1 BTAD
BTB BURP Bac_DnaA_C Bac_rhodopsin Beach
Beta-Casp Beta-TrCP_D BetaGal_dom2 Bgal_small_N Biotin_carb_C
Brix Btz C8 CAD CAMSAP_CKK
CAP10 CAP_GLY CARP CAT CBM49
CBM_10 CBM_2 CBM_25 CBM_3 CBM_X
CBS CDC37_C CDC37_M CDC37_N CDC48_2
CDC48_N CGGC CHAD CHB_HEX CHZ
CK_II_beta CLH CM_2 COG6 CO_deh_flav_C
CP12 CPSase_L_D3 CPSase_sm_chain CPW_WPC CRA
CRAL_TRIO_N CRISPR_assoc CRS1_YhbY CTLH CTNS
CUE CVNH CXC CYCLIN CYTH
CaMBD CaM_binding Ca_chan_IQ CactinC_cactus Cadherin_pro
Candida_ALS_N Carb_anhydrase Catalase Cation_ATPase_N Cg6151-P
ChSh Citrate_ly_lig ClpB_D2-small CoA_binding CoA_trans
CobW_C Cog4 CorC_HlyC CpcD Cpl-7
Cpn10 Cullin_Nedd8 Cupin_1 CxxC_CXXC_SSSS Cyanate_lyase
D-ser_dehydrat DALR_1 DALR_2 DBC1 DBP10CT
DBR1 DCD DCP2 DCX DDHD
DDRGK DELLA DENN DEXDc2 DHDPS
DHHA2 DIL DIRP DKCLD DM10
DM11 DM13 DM14 DM15 DM16
DM3 DM5 DM7 DM8 DM9
DPBB_1 DRY_EERY DTW DUF1041 DUF1086
DUF1220 DUF1237 DUF1338 DUF1518 DUF167
DUF1704 DUF1713 DUF1716 DUF1719 DUF1741
DUF1751 DUF1767 DUF1771 DUF1785 DUF1856
DUF1866 DUF1899 DUF1900 DUF1907 DUF1943
DUF1944 DUSP Dabb Dak1_2 Dak2
DeoC DeoRC DnaG_DnaB_bind DnaJ Drf_FH3
Drf_GBD DysFC DysFN EB_dh EF1_GNE
EFG_C EFG_IV EKR ELFV_dehydrog ETF
EZ_HEAT Elong-fact-P_C FABD FDX-ACB FMN_bind
FRG Fe_hyd_SSU FeoA Flavin_Reduct Flavokinase
FolB FtsA GAL4 GDNF GIT
GYF GYR Gal-bind_lectin GatB_Yqey Germane
Gp_dh_N Grip HA2 HAT HDc
HELICc2 HEPN HIRAN HTTM HWE_HK
IBR IDEAL IG_FLMN JAB_MPN KIND
L51_S25_CI-B8 LA LH2 LITAF LON
LRRcap Lactamase_B LeuA_dimer Lig_chan-Glu_bd LisH
MGS MIF4G MIT MORN MR_MLE
Mad3_BUB1_I Malic_M MbtH MgtE_N MltA
MoCF_biosynth Molybdop_Fe4S4 Mterf NADH-G_4Fe-4S_3 NADH_4Fe-4S
NDK NEBU NIL NPCBM Nfu_N
OMPdecase OmpH P-II PA14 PAM
PAW PB1 PCRF PGAM PHB
PIG-X PINT PINc PKS_AT PKS_DH
PKS_ER PKS_KR PKS_KS PKS_MT PKS_PP
PKS_TE PLEC PMEI PP2C_SIG PROF
PSN PWI PWWP PYNP_C PepX_C
PepX_N PhnA_Zn_Ribbon PlsC PolyA Prim_Zn_Ribbon
Pro-kuma_activ ProQ ProRS-C_1 Pro_CA Proteasome_A_N
Pumilio QLQ R3H RAP RES
RINGv RL11 RNB RPEL RRM_1
RUN RelA_SpoT Robl_LC7 RuBisCO_small S1
SAF SAM_PNT SATase_N SEC63 SEP
SHR3_chaperone SMI1_KNR4 SNc SOCS_box SRP54
SRP54_N STI1 SWAP SWIB SecA_DEAD
SecA_PP_bind Semialdhyde_dh Sorb Spc7 SpoU_sub_bind
SprT SynN T5orf172 TAFH TAP_C
TGc THEG THUMP THY TLC
TLDc TPK_B1_binding TPR TUDOR TilS_C
Tim44 Transket_pyr Tubulin Tubulin_C UAS
UBA_e1_C UDPG_MGDP_dh_C UIM UreE_C UreE_N
V4R VKc VRR_NUC VWC_out WGR
WHEP-TRS WHy WRKY WSN WWE
YceI ZM ZipA_C ZnF_CDGSH ZnF_TAZ
ZnF_TTF ZnF_UBR1 Zpr1 alkPPc c-SKI_SMAD_bind
calpain_III cwf21 dDENN eIF1a eIF2B_5
eIF6 rADc tRNA_SAD uDENN zf-C4_ClpX

NCI Database         Panther Database         Reactome Database         WikiPathway Database        

NCI Pathways
ALK1 pathway ALK1 signaling events
ALK2 signaling events AP-1 transcription factor network
ATF-2 transcription factor network ATM pathway
ATR signaling pathway Alpha-synuclein signaling
Alpha4 beta1 integrin signaling events Alpha6 beta4 integrin-ligand interactions
Alpha9 beta1 integrin signaling events AlphaE beta7 integrin cell surface interactions
Alternative NF-kappaB pathway Angiopoietin receptor Tie2-mediated signaling
Arf1 pathway Arf6 downstream pathway
Arf6 signaling events Arf6 trafficking events
Atypical NF-kappaB pathway Aurora A signaling
Aurora B signaling Aurora C signaling
BARD1 signaling events BCR signaling pathway
BMP receptor signaling Beta1 integrin cell surface interactions
Beta2 integrin cell surface interactions Beta3 integrin cell surface interactions
Beta5 beta6 beta7 and beta8 integrin cell surface interactions C-MYB transcription factor network
C-MYC pathway CD40/CD40L signaling
CDC42 signaling events CXCR3-mediated signaling events
CXCR4-mediated signaling events Calcineurin-regulated NFAT-dependent transcription in lymphocytes
Calcium signaling in the CD4+ TCR pathway Canonical NF-kappaB pathway
Canonical Wnt signaling pathway Caspase Cascade in Apoptosis
Cellular roles of Anthrax toxin Ceramide signaling pathway
Circadian rhythm pathway Class I PI3K signaling events
Class I PI3K signaling events mediated by Akt Class IB PI3K non-lipid kinase events
Coregulation of Androgen receptor activity DNA-PK pathway in nonhomologous end joining
Degradation of beta catenin Direct p53 effectors
Downstream signaling in naïve CD8+ T cells E-cadherin signaling events
E-cadherin signaling in keratinocytes E-cadherin signaling in the nascent adherens junction
E2F transcription factor network EGF receptor (ErbB1) signaling pathway
EGFR-dependent Endothelin signaling events EPHA forward signaling
EPHA2 forward signaling EPHB forward signaling
EPO signaling pathway Effects of Botulinum toxin
Endogenous TLR signaling Endothelins
Ephrin A reverse signaling Ephrin B reverse signaling
EphrinA-EPHA pathway EphrinB-EPHB pathway
ErbB receptor signaling network ErbB1 downstream signaling
ErbB2/ErbB3 signaling events ErbB4 signaling events
FAS (CD95) signaling pathway FGF signaling pathway
FOXA transcription factor networks FOXA1 transcription factor network
FOXA2 and FOXA3 transcription factor networks FOXM1 transcription factor network
Fanconi anemia pathway Fc-epsilon receptor I signaling in mast cells
FoxO family signaling GMCSF-mediated signaling events
Glucocorticoid receptor regulatory network Glypican 1 network
Glypican 2 network Glypican 3 network
Glypican pathway HIF-1-alpha transcription factor network
HIF-2-alpha transcription factor network HIV-1 Nef: Negative effector of Fas and TNF-alpha
Hedgehog signaling events mediated by Gli proteins Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
IFN-gamma pathway IGF1 pathway
IL1-mediated signaling events IL12 signaling mediated by STAT4
IL12-mediated signaling events IL2 signaling events mediated by PI3K
IL2 signaling events mediated by STAT5 IL2-mediated signaling events
IL23-mediated signaling events IL27-mediated signaling events
IL3-mediated signaling events IL4-mediated signaling events
IL5-mediated signaling events IL6-mediated signaling events
IL8- and CXCR1-mediated signaling events IL8- and CXCR2-mediated signaling events
IL8-mediated signaling events Insulin Pathway
Insulin-mediated glucose transport Integrin family cell surface interactions
Integrin-linked kinase signaling Integrins in angiogenesis
Internalization of ErbB1 JNK signaling in the CD4+ TCR pathway
LKB1 signaling events LPA receptor mediated events
LPA4-mediated signaling events Lissencephaly gene (LIS1) in neuronal migration and development
N-cadherin signaling events Nectin adhesion pathway
Nephrin/Neph1 signaling in the kidney podocyte Netrin-mediated signaling events
Neurotrophic factor-mediated Trk receptor signaling Noncanonical Wnt signaling pathway
Nongenotropic Androgen signaling Notch signaling pathway
Notch-mediated HES/HEY network Osteopontin-mediated events
PAR1-mediated thrombin signaling events PAR4-mediated thrombin signaling events
PDGF receptor signaling network PDGFR-alpha signaling pathway
PDGFR-beta signaling pathway PLK1 signaling events
PLK2 and PLK4 events PLK3 signaling events
Plasma membrane estrogen receptor signaling Plexin-D1 Signaling
Polo-like kinase signaling events in the cell cycle Posttranslational regulation of adherens junction stability and dissassembly
Presenilin action in Notch and Wnt signaling Proteoglycan syndecan-mediated signaling events
RAC1 signaling pathway RXR and RAR heterodimerization with other nuclear receptor
Rapid glucocorticoid signaling Ras signaling in the CD4+ TCR pathway
Reelin signaling pathway Regulation of Androgen receptor activity
Regulation of CDC42 activity Regulation of RAC1 activity
Regulation of Ras family activation Regulation of RhoA activity
Regulation of Telomerase Regulation of cytoplasmic and nuclear SMAD2/3 signaling
Regulation of nuclear SMAD2/3 signaling Regulation of nuclear beta catenin signaling and target gene transcription
Regulation of p38-alpha and p38-beta Regulation of retinoblastoma protein
Retinoic acid receptors-mediated signaling RhoA signaling pathway
Role of Calcineurin-dependent NFAT signaling in lymphocytes S1P1 pathway
S1P2 pathway S1P3 pathway
S1P4 pathway S1P5 pathway
SHP2 signaling Signaling by Aurora kinases
Signaling events mediated by HDAC Class I Signaling events mediated by HDAC Class II
Signaling events mediated by HDAC Class III Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
Signaling events mediated by PRL Signaling events mediated by PTP1B
Signaling events mediated by Stem cell factor receptor (c-Kit) Signaling events mediated by TCPTP
Signaling events mediated by VEGFR1 and VEGFR2 Signaling events mediated by focal adhesion kinase
Signaling events mediated by the Hedgehog family Signaling events regulated by Ret tyrosine kinase
Signaling mediated by p38-alpha and p38-beta Signaling mediated by p38-gamma and p38-delta
Sphingosine 1-phosphate (S1P) pathway Stabilization and expansion of the E-cadherin adherens junction
Sumoylation by RanBP2 regulates transcriptional repression Syndecan-1-mediated signaling events
Syndecan-2-mediated signaling events Syndecan-3-mediated signaling events
Syndecan-4-mediated signaling events TCR signaling in naïve CD4+ T cells
TCR signaling in naïve CD8+ T cells TGF-beta receptor signaling
TNF receptor signaling pathway TRAIL signaling pathway
Thrombin/protease-activated receptor (PAR) pathway Thromboxane A2 receptor signaling
Trk receptor signaling mediated by PI3K and PLC-gamma Trk receptor signaling mediated by the MAPK pathway
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling VEGF and VEGFR signaling network
VEGFR1 specific signals VEGFR3 signaling in lymphatic endothelium
Validated nuclear estrogen receptor alpha network Validated nuclear estrogen receptor beta network
Validated targets of C-MYC transcriptional activation Validated targets of C-MYC transcriptional repression
Validated transcriptional targets of AP1 family members Fra1 and Fra2 Validated transcriptional targets of TAp63 isoforms
Validated transcriptional targets of deltaNp63 isoforms Visual signal transduction: Cones
Visual signal transduction: Rods Wnt signaling network
a4b7 Integrin signaling a6b1 and a6b4 Integrin signaling
amb2 Integrin signaling mTOR signaling pathway
p38 MAPK signaling pathway p38 signaling mediated by MAPKAP kinases
p53 pathway p73 transcription factor network
p75(NTR)-mediated signaling
Panther Pathways

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2-arachidonoylglycerol biosynthesis
5-Hydroxytryptamine biosynthesis 5-Hydroxytryptamine degredation
5HT1 type receptor mediated signaling pathway 5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway 5HT4 type receptor mediated signaling pathway
ATP synthesis Acetate utilization
Adenine and hypoxanthine salvage pathway Adrenaline and noradrenaline biosynthesis
Alanine biosynthesis Alpha adrenergic receptor signaling pathway
Alzheimer disease-amyloid secretase pathway Alzheimer disease-presenilin pathway
Aminobutyrate degradation Anandamide degradation
Androgen/estrogene/progesterone biosynthesis Angiogenesis
Angiotensin II-stimulated signaling through G proteins and beta-arrestin Apoptosis signaling pathway
Arginine biosynthesis Ascorbate degradation
Asparagine and aspartate biosynthesis Axon guidance mediated by Slit/Robo
Axon guidance mediated by netrin Axon guidance mediated by semaphorins
B cell activation Beta1 adrenergic receptor signaling pathway
Beta2 adrenergic receptor signaling pathway Beta3 adrenergic receptor signaling pathway
Blood coagulation Bupropion degradation
Cadherin signaling pathway Carnitine metabolism
Cell cycle Cholesterol biosynthesis
Circadian clock system Coenzyme A biosynthesis
Coenzyme A linked carnitine metabolism Cortocotropin releasing factor receptor signaling pathway
Cysteine biosynthesis Cytoskeletal regulation by Rho GTPase
DNA replication De novo purine biosynthesis
De novo pyrimidine deoxyribonucleotide biosynthesis De novo pyrimidine ribonucleotides biosythesis
Dopamine receptor mediated signaling pathway EGF receptor signaling pathway
Endogenous cannabinoid signaling Endothelin signaling pathway
Enkephalin release FAS signaling pathway
FGF signaling pathway Flavin biosynthesis
Formyltetrahydroformate biosynthesis Fructose galactose metabolism
GABA-B receptor II signaling Gamma-aminobutyric acid synthesis
General transcription by RNA polymerase I General transcription regulation
Glutamine glutamate conversion Glycolysis
Gonadotropin-releasing hormone receptor pathway Hedgehog signaling pathway
Heme biosynthesis Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
Histamine H1 receptor mediated signaling pathway Histamine H2 receptor mediated signaling pathway
Histamine synthesis Huntington disease
Hypoxia response via HIF activation Inflammation mediated by chemokine and cytokine signaling pathway
Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade Insulin/IGF pathway-protein kinase B signaling cascade
Integrin signalling pathway Interferon-gamma signaling pathway
Interleukin signaling pathway Ionotropic glutamate receptor pathway
Isoleucine biosynthesis JAK/STAT signaling pathway
Leucine biosynthesis Lipoate_biosynthesis
Mannose metabolism Metabotropic glutamate receptor group I pathway
Metabotropic glutamate receptor group II pathway Metabotropic glutamate receptor group III pathway
Methionine biosynthesis Methylcitrate cycle
Methylmalonyl pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway N-acetylglucosamine metabolism
Nicotine degradation Nicotine pharmacodynamics pathway
Nicotinic acetylcholine receptor signaling pathway Notch signaling pathway
O-antigen biosynthesis Opioid prodynorphin pathway
Opioid proenkephalin pathway Opioid proopiomelanocortin pathway
Ornithine degradation Oxidative stress response
Oxytocin receptor mediated signaling pathway P53 pathway feedback loops 1
PDGF signaling pathway PI3 kinase pathway
Parkinson disease Pentose phosphate pathway
Phenylethylamine degradation Plasminogen activating cascade
Proline biosynthesis Purine metabolism
Pyridoxal phosphate salvage pathway Pyridoxal-5-phosphate biosynthesis
Pyrimidine Metabolism Pyruvate metabolism
Ras Pathway S-adenosylmethionine biosynthesis
Salvage pyrimidine deoxyribonucleotides Salvage pyrimidine ribonucleotides
Serine glycine biosynthesis Succinate to proprionate conversion
Sulfate assimilation Synaptic vesicle trafficking
T cell activation TCA cycle
TGF-beta signaling pathway Tetrahydrofolate biosynthesis
Thiamin metabolism Threonine biosynthesis
Thyrotropin-releasing hormone receptor signaling pathway Toll receptor signaling pathway
Transcription regulation by bZIP transcription factor Triacylglycerol metabolism
Ubiquitin proteasome pathway VEGF signaling pathway
Valine biosynthesis Vasopressin synthesis
Vitamin B6 metabolism Vitamin D metabolism and pathway
Wnt signaling pathway Xanthine and guanine salvage pathway
mRNA splicing p38 MAPK pathway
p53 pathway p53 pathway by glucose deprivation
p53 pathway feedback loops 2
Reactome Pathways

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2-LTR circle formation
3' -UTR-mediated translational regulation 5-Phosphoribose 1-diphosphate biosynthesis
A tetrasaccharide linker sequence is required for GAG synthesis A third proteolytic cleavage releases NICD
ABC-family proteins mediated transport ABCA transporters in lipid homeostasis
ABH2 mediated Reversal of Alkylation Damage ABH3 mediated Reversal of Alkylation Damage
ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 12
AKT phosphorylates targets in the cytosol AKT phosphorylates targets in the nucleus
AKT-mediated inactivation of FOXO1A AMPK inhibits chREBP transcriptional activation activity
APC-Cdc20 mediated degradation of Nek2A APC/C-mediated degradation of cell cycle proteins
APC/C:Cdc20 mediated degradation of Cyclin B APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdc20 mediated degradation of mitotic proteins APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
APOBEC3G mediated resistance to HIV-1 infection ARMS-mediated activation
ATF4 activates genes ATF6-alpha activates chaperone genes
ATF6-alpha activates chaperones ATM mediated phosphorylation of repair proteins
ATM mediated response to DNA double-strand break ATP sensitive Potassium channels
AUF1 (hnRNP D0) destabilizes mRNA Abacavir metabolism
Abacavir transmembrane transport Abacavir transport and metabolism
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate Abnormal metabolism in phenylketonuria
Abortive elongation of HIV-1 transcript in the absence of Tat Acetylation
Acetylcholine Binding And Downstream Events Acetylcholine Neurotransmitter Release Cycle
Acetylcholine regulates insulin secretion Acrosome Reaction
Activated NOTCH1 Transmits Signal to the Nucleus Activated TLR4 signalling
Activated point mutants of FGFR2 Activation and oligomerization of BAK protein
Activation of AMPA receptors Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Activation of ATR in response to replication stress Activation of BAD and translocation to mitochondria
Activation of BH3-only proteins Activation of BIM and translocation to mitochondria
Activation of BMF and translocation to mitochondria Activation of C3 and C5
Activation of Ca-permeable Kainate Receptor Activation of CaMK IV
Activation of DNA fragmentation factor Activation of G protein gated Potassium channels
Activation of GABAB receptors Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
Activation of Kainate Receptors upon glutamate binding Activation of Matrix Metalloproteinases
Activation of NF-kappaB in B cells Activation of NIMA Kinases NEK9, NEK6, NEK7
Activation of NMDA receptor upon glutamate binding and postsynaptic events Activation of NOXA and translocation to mitochondria
Activation of Na-permeable Kainate Receptors Activation of Nicotinic Acetylcholine Receptors
Activation of PKB Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Activation of PUMA and translocation to mitochondria Activation of RAS in B cells
Activation of Rac Activation of TRKA receptors
Activation of caspases through apoptosome-mediated cleavage Activation of gene expression by SREBF (SREBP)
Activation of the AP-1 family of transcription factors Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Activation of the phototransduction cascade Activation of the pre-replicative complex
Activation, myristolyation of BID and translocation to mitochondria Activation, translocation and oligomerization of BAX
Acyl chain remodeling of CL Acyl chain remodeling of DAG and TAG
Acyl chain remodelling of PC Acyl chain remodelling of PE
Acyl chain remodelling of PG Acyl chain remodelling of PI
Acyl chain remodelling of PS Adaptive Immune System
Adenosine P1 receptors Adenylate cyclase activating pathway
Adenylate cyclase inhibitory pathway Adherens junctions interactions
Adrenaline signalling through Alpha-2 adrenergic receptor Adrenaline,noradrenaline inhibits insulin secretion
Adrenoceptors Advanced glycosylation endproduct receptor signaling
Agmatine biosynthesis Alpha-defensins
Alpha-oxidation of phytanate Alternative complement activation
Amine Oxidase reactions Amine compound SLC transporters
Amine ligand-binding receptors Amine-derived hormones
Amino Acid conjugation Amino acid and oligopeptide SLC transporters
Amino acid synthesis and interconversion (transamination) Amino acid transport across the plasma membrane
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Amplification of signal from the kinetochores
Amyloids Anchoring fibril formation
Androgen biosynthesis Antagonism of Activin by Follistatin
Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Antigen processing-Cross presentation Antigen processing: Ubiquitination & Proteasome degradation
Antiviral mechanism by IFN-stimulated genes Apoptosis
Apoptosis induced DNA fragmentation Apoptotic cleavage of cell adhesion proteins
Apoptotic cleavage of cellular proteins Apoptotic execution phase
Apoptotic factor-mediated response Aquaporin-mediated transport
Arachidonate production from DAG Arachidonic acid metabolism
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 Asparagine N-linked glycosylation
Assembly Of The HIV Virion Assembly of Viral Components at the Budding Site
Assembly of collagen fibrils and other multimeric structures Assembly of the ORC complex at the origin of replication
Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks Assembly of the RAD51-ssDNA nucleoprotein complex
Assembly of the pre-replicative complex Association of TriC/CCT with target proteins during biosynthesis
Association of licensing factors with the pre-replicative complex Astrocytic Glutamate-Glutamine Uptake And Metabolism
Asymmetric localization of PCP proteins Attachment of GPI anchor to uPAR
Attenuation phase Autodegradation of Cdh1 by Cdh1:APC/C
Autodegradation of the E3 ubiquitin ligase COP1 Autointegration results in viral DNA circles
Axon guidance Axonal growth inhibition (RHOA activation)
Axonal growth stimulation BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
BMAL1:CLOCK,NPAS2 activates circadian gene expression Base Excision Repair
Base-Excision Repair, AP Site Formation Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
Basigin interactions Beta defensins
Beta oxidation of butanoyl-CoA to acetyl-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
Beta oxidation of hexanoyl-CoA to butanoyl-CoA Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
Beta oxidation of myristoyl-CoA to lauroyl-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Beta oxidation of palmitoyl-CoA to myristoyl-CoA Beta-catenin phosphorylation cascade
Beta-oxidation of pristanoyl-CoA Beta-oxidation of very long chain fatty acids
Bicarbonate transporters Bile acid and bile salt metabolism
Bile salt and organic anion SLC transporters Binding and Uptake of Ligands by Scavenger Receptors
Binding and entry of HIV virion Biological oxidations
Biosynthesis of A2E, implicated in retinal degradation Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Biotin transport and metabolism Branched-chain amino acid catabolism
Breakdown of the nuclear lamina Budding and maturation of HIV virion
Butyrate Response Factor 1 (BRF1) destabilizes mRNA C6 deamination of adenosine
CD28 co-stimulation CD28 dependent PI3K/Akt signaling
CD28 dependent Vav1 pathway CDC6 association with the ORC:origin complex
CDK-mediated phosphorylation and removal of Cdc6 CDO in myogenesis
CDT1 association with the CDC6:ORC:origin complex CHL1 interactions
COPI Mediated Transport COPII (Coat Protein 2) Mediated Vesicle Transport
COX reactions CREB phosphorylation
CREB phosphorylation through the activation of Adenylate Cyclase CREB phosphorylation through the activation of CaMKII
CREB phosphorylation through the activation of CaMKK CREB phosphorylation through the activation of Ras
CRMPs in Sema3A signaling CS/DS degradation
CTLA4 inhibitory signaling CYP2E1 reactions
Ca-dependent events Ca2+ activated K+ channels
Ca2+ pathway CaM pathway
CaMK IV-mediated phosphorylation of CREB Calcitonin-like ligand receptors
Calmodulin induced events Calnexin/calreticulin cycle
Cam-PDE 1 activation Cap-dependent Translation Initiation
Carnitine synthesis Caspase-8 activation
Caspase-mediated cleavage of cytoskeletal proteins Catecholamine biosynthesis
Cation-coupled Chloride cotransporters Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Cell Cycle Cell Cycle Checkpoints
Cell Cycle, Mitotic Cell death signalling via NRAGE, NRIF and NADE
Cell junction organization Cell surface interactions at the vascular wall
Cell-Cell communication Cell-cell junction organization
Cell-extracellular matrix interactions Cellular Senescence
Cellular response to heat stress Cellular response to hypoxia
Cellular responses to stress Centrosome maturation
Ceramide signalling ChREBP activates metabolic gene expression
Chaperonin-mediated protein folding Chemokine receptors bind chemokines
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Cholesterol biosynthesis
Chondroitin sulfate biosynthesis Chondroitin sulfate/dermatan sulfate metabolism
Chromatin modifying enzymes Chromatin organization
Chromosome Maintenance Chylomicron-mediated lipid transport
Circadian Clock Citric acid cycle (TCA cycle)
Class A/1 (Rhodopsin-like receptors) Class B/2 (Secretin family receptors)
Class C/3 (Metabotropic glutamate/pheromone receptors) Class I MHC mediated antigen processing & presentation
Class II GLUTs Classical Kir channels
Classical antibody-mediated complement activation Clathrin derived vesicle budding
Clearance of Nuclear Envelope Membranes from Chromatin Cleavage of Growing Transcript in the Termination Region
Cleavage of the damaged purine Cleavage of the damaged pyrimidine
Cobalamin (Cbl, vitamin B12) transport and metabolism Coenzyme A biosynthesis
Cohesin Loading onto Chromatin Collagen biosynthesis and modifying enzymes
Collagen degradation Collagen formation
Common Pathway Complement cascade
Condensation of Prometaphase Chromosomes Condensation of Prophase Chromosomes
Conjugation of benzoate with glycine Conjugation of carboxylic acids
Conjugation of phenylacetate with glutamine Conjugation of salicylate with glycine
Constitutive PI3K/AKT Signaling in Cancer Constitutive Signaling by NOTCH1 HD Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Costimulation by the CD28 family
Creatine metabolism Creation of C4 and C2 activators
Cross-presentation of particulate exogenous antigens (phagosomes) Cross-presentation of soluble exogenous antigens (endosomes)
Crosslinking of collagen fibrils Cyclin A/B1 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry Cyclin B2 mediated events
Cyclin D associated events in G1 Cyclin E associated events during G1/S transition
Cysteine formation from homocysteine Cytochrome P450 - arranged by substrate type
Cytochrome c-mediated apoptotic response Cytokine Signaling in Immune system
Cytosolic iron-sulfur cluster assembly Cytosolic sensors of pathogen-associated DNA
Cytosolic sulfonation of small molecules Cytosolic tRNA aminoacylation
DAG and IP3 signaling DAP12 interactions
DAP12 signaling DARPP-32 events
DCC mediated attractive signaling DEx/H-box helicases activate type I IFN and inflammatory cytokines production
DNA Damage Bypass DNA Damage Recognition in GG-NER
DNA Damage Reversal DNA Damage/Telomere Stress Induced Senescence
DNA Repair DNA Replication
DNA Replication Pre-Initiation DNA replication initiation
DNA strand elongation DSCAM interactions
Deadenylation of mRNA Deadenylation-dependent mRNA decay
Death Receptor Signalling Defective AMN causes hereditary megaloblastic anemia 1
Defective BTD causes biotidinase deficiency Defective CD320 causes methylmalonic aciduria
Defective CUBN causes hereditary megaloblastic anemia 1 Defective GIF causes intrinsic factor deficiency
Defective HLCS causes multiple carboxylase deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective MMAA causes methylmalonic aciduria type cblA Defective MMAB causes methylmalonic aciduria type cblB
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MUT causes methylmalonic aciduria mut type Defective TCN2 causes hereditary megaloblastic anemia
Defects in biotin (Btn) metabolism Defects in cobalamin (B12) metabolism
Defects in vitamin and cofactor metabolism Defensins
Degradation of GABA Degradation of beta-catenin by the destruction complex
Degradation of cysteine and homocysteine Degradation of the extracellular matrix
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels Depolymerisation of the Nuclear Lamina
Deposition of new CENPA-containing nucleosomes at the centromere Depurination
Depyrimidination Dermatan sulfate biosynthesis
Detoxification of Reactive Oxygen Species Developmental Biology
Digestion of dietary carbohydrate Digestion of dietary lipid
Dimerization of procaspase-8 Disease
Diseases associated with visual transduction Disinhibition of SNARE formation
Displacement of DNA glycosylase by APE1 Dissolution of Fibrin Clot
Dopamine Neurotransmitter Release Cycle Dopamine clearance from the synaptic cleft
Dopamine receptors Double-Strand Break Repair
Downregulation of ERBB2:ERBB3 signaling Downregulation of ERBB4 signaling
Downregulation of SMAD2/3:SMAD4 transcriptional activity Downregulation of TGF-beta receptor signaling
Downstream TCR signaling Downstream signal transduction
Downstream signaling events of B Cell Receptor (BCR) Downstream signaling of activated FGFR
Dual incision reaction in GG-NER Dual incision reaction in TC-NER
E2F mediated regulation of DNA replication E2F-enabled inhibition of pre-replication complex formation
ECM proteoglycans EGFR Transactivation by Gastrin
EGFR downregulation EGFR interacts with phospholipase C-gamma
ER Quality Control Compartment (ERQC) ER to Golgi Transport
ER-Phagosome pathway ERK activation
ERK/MAPK targets ERK1 activation
ERK2 activation ERKs are inactivated
Early Phase of HIV Life Cycle Effects of PIP2 hydrolysis
Eicosanoid ligand-binding receptors Eicosanoids
Elastic fibre formation Electric Transmission Across Gap Junctions
Electron transport from NADPH to Ferredoxin Elevation of cytosolic Ca2+ levels
Elongation arrest and recovery Endogenous sterols
Endosomal Sorting Complex Required For Transport (ESCRT) Endosomal/Vacuolar pathway
Energy dependent regulation of mTOR by LKB1-AMPK Entry of Influenza Virion into Host Cell via Endocytosis
Enzymatic degradation of Dopamine by monoamine oxidase Enzymatic degradation of dopamine by COMT
Epigenetic regulation of gene expression Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide Establishment of Sister Chromatid Cohesion
Estrogen biosynthesis Ethanol oxidation
Eukaryotic Translation Elongation Eukaryotic Translation Initiation
Eukaryotic Translation Termination Export of Viral Ribonucleoproteins from Nucleus
Extension of Telomeres Extracellular matrix organization
Extrinsic Pathway Extrinsic Pathway for Apoptosis
FBXW7 Mutants and NOTCH1 in Cancer FCERI mediated Ca+2 mobilization
FCERI mediated MAPK activation FCERI mediated NF-kB activation
FCGR activation FGFR ligand binding and activation
FGFR1 ligand binding and activation FGFR1b ligand binding and activation
FGFR1c and Klotho ligand binding and activation FGFR1c ligand binding and activation
FGFR2 ligand binding and activation FGFR2b ligand binding and activation
FGFR2c ligand binding and activation FGFR3 ligand binding and activation
FGFR3b ligand binding and activation FGFR3c ligand binding and activation
FGFR4 ligand binding and activation FMO oxidizes nucleophiles
FRS2-mediated cascade Facilitative Na+-independent glucose transporters
Factors involved in megakaryocyte development and platelet production Fanconi Anemia pathway
FasL/ CD95L signaling Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
Fatty Acyl-CoA Biosynthesis Fatty acid, triacylglycerol, and ketone body metabolism
Fatty acids Fc epsilon receptor (FCERI) signaling
Fcgamma receptor (FCGR) dependent phagocytosis Fertilization
Fibronectin matrix formation Ficolins bind to repetitive carbohydrate structures on the target cell surface
Folding of actin by CCT/TriC Formation of ATP by chemiosmotic coupling
Formation of Fibrin Clot (Clotting Cascade) Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of RNA Pol II elongation complex
Formation of Senescence-Associated Heterochromatin Foci (SAHF) Formation of a pool of free 40S subunits
Formation of annular gap junctions Formation of apoptosome
Formation of editosomes by ADAR proteins Formation of incision complex in GG-NER
Formation of the Early Elongation Complex Formation of the Editosome
Formation of the HIV-1 Early Elongation Complex Formation of the active cofactor, UDP-glucuronate
Formation of the ternary complex, and subsequently, the 43S complex Formation of transcription-coupled NER (TC-NER) repair complex
Formation of tubulin folding intermediates by CCT/TriC Formyl peptide receptors bind formyl peptides and many other ligands
Free fatty acid receptors Free fatty acids regulate insulin secretion
Frs2-mediated activation Fructose catabolism
G alpha (12/13) signalling events G alpha (i) signalling events
G alpha (q) signalling events G alpha (s) signalling events
G alpha (z) signalling events G beta:gamma signalling through PI3Kgamma
G beta:gamma signalling through PLC beta G protein gated Potassium channels
G-protein activation G-protein beta:gamma signalling
G-protein mediated events G0 and Early G1
G1 Phase G1/S DNA Damage Checkpoints
G1/S Transition G1/S-Specific Transcription
G2 Phase G2/M Checkpoints
G2/M DNA damage checkpoint G2/M DNA replication checkpoint
G2/M Transition GAB1 signalosome
GABA A (rho) receptor activation GABA A receptor activation
GABA B receptor activation GABA receptor activation
GABA synthesis GABA synthesis, release, reuptake and degradation
GP1b-IX-V activation signalling GPCR downstream signaling
GPCR ligand binding GPVI-mediated activation cascade
GRB2 events in EGFR signaling GRB2 events in ERBB2 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins GRB7 events in ERBB2 signaling
GTP hydrolysis and joining of the 60S ribosomal subunit Galactose catabolism
Gamma-carboxylation of protein precursors Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
Gap junction assembly Gap junction degradation
Gap junction trafficking Gap junction trafficking and regulation
Gap-filling DNA repair synthesis and ligation in GG-NER Gap-filling DNA repair synthesis and ligation in TC-NER
Gastrin-CREB signalling pathway via PKC and MAPK Gene Expression
Generation of second messenger molecules Generic Transcription Pathway
Global Genomic NER (GG-NER) Glucagon signaling in metabolic regulation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-type ligand receptors
Glucocorticoid biosynthesis Gluconeogenesis
Glucose metabolism Glucose transport
Glucuronidation Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
Glutamate Neurotransmitter Release Cycle Glutathione conjugation
Glutathione synthesis and recycling Glycerophospholipid biosynthesis
Glycogen breakdown (glycogenolysis) Glycogen storage diseases
Glycogen synthesis Glycolysis
Glycoprotein hormones Glycosaminoglycan metabolism
Glycosphingolipid metabolism Glyoxylate metabolism
Golgi Associated Vesicle Biogenesis Golgi Cisternae Pericentriolar Stack Reorganization
Golgi to ER Retrograde Transport Growth hormone receptor signaling
HATs acetylate histones HCN channels
HDL-mediated lipid transport HIV Infection
HIV Life Cycle HIV Transcription Elongation
HIV Transcription Initiation HIV elongation arrest and recovery
HS-GAG biosynthesis HS-GAG degradation
HSF1 activation HSF1-dependent transactivation
Heme biosynthesis Heme degradation
Hemostasis Heparan sulfate/heparin (HS-GAG) metabolism
Hexose transport Highly calcium permeable nicotinic acetylcholine receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly sodium permeable acetylcholine nicotinic receptors
Histamine receptors Histidine catabolism
Homologous DNA pairing and strand exchange Homologous Recombination Repair
Homologous recombination repair of replication-independent double-strand breaks Hormone ligand-binding receptors
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Host Interactions of HIV factors
Host Interactions with Influenza Factors HuR stabilizes mRNA
Hyaluronan biosynthesis and export Hyaluronan metabolism
Hyaluronan uptake and degradation Hydrolysis of LPC
Hydrolysis of LPE Hydroxycarboxylic acid-binding receptors
Hypusine synthesis from eIF5A-lysine IGF1R signaling cascade
IKK complex recruitment mediated by RIP1 IRAK1 recruits IKK complex
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation IRAK2 mediated activation of TAK1 complex
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation IRE1alpha activates chaperones
IRF3 mediated activation of type 1 IFN IRF3-mediated induction of type I IFN
IRS activation IRS-mediated signalling
IRS-related events IRS-related events triggered by IGF1R
ISG15 antiviral mechanism Immune System
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Import of palmitoyl-CoA into the mitochondrial matrix
Inactivation of APC/C via direct inhibition of the APC/C complex Inactivation of Cdc42 and Rac
Inactivation, recovery and regulation of the phototransduction cascade Incretin synthesis, secretion, and inactivation
Inflammasomes Influenza Infection
Influenza Life Cycle Influenza Viral RNA Transcription and Replication
Influenza Virus Induced Apoptosis Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Inhibition of HSL Inhibition of Host mRNA Processing and RNA Silencing
Inhibition of PKR Inhibition of TSC complex formation by PKB
Inhibition of adenylate cyclase pathway Inhibition of replication initiation of damaged DNA by RB1/E2F1
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components Initial triggering of complement
Initiation of Nuclear Envelope Reformation Innate Immune System
Inositol phosphate metabolism Inositol transporters
Insulin effects increased synthesis of Xylulose-5-Phosphate Insulin processing
Insulin receptor recycling Insulin receptor signalling cascade
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA Integration of energy metabolism
Integration of provirus Integration of viral DNA into host genomic DNA
Integrin alphaIIb beta3 signaling Integrin cell surface interactions
Interaction With Cumulus Cells Interaction With The Zona Pellucida
Interaction between L1 and Ankyrins Interactions of Rev with host cellular proteins
Interactions of Tat with host cellular proteins Interactions of Vpr with host cellular proteins
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate Interconversion of polyamines
Interferon Signaling Interferon alpha/beta signaling
Interferon gamma signaling Interleukin receptor SHC signaling
Interleukin-1 processing Interleukin-1 signaling
Interleukin-2 signaling Interleukin-3, 5 and GM-CSF signaling
Interleukin-6 signaling Interleukin-7 signaling
Intrinsic Pathway Intrinsic Pathway for Apoptosis
Inwardly rectifying K+ channels Ion channel transport
Ion transport by P-type ATPases Ionotropic activity of Kainate Receptors
Iron uptake and transport JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
KSRP destabilizes mRNA Keratan sulfate biosynthesis
Keratan sulfate degradation Keratan sulfate/keratin metabolism
Ketone body metabolism Kinesins
Klotho-mediated ligand binding L13a-mediated translational silencing of Ceruloplasmin expression
L1CAM interactions LDL-mediated lipid transport
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Lagging Strand Synthesis
Laminin interactions Late Phase of HIV Life Cycle
Latent infection of Homo sapiens with Mycobacterium tuberculosis Leading Strand Synthesis
Lectin pathway of complement activation Leukotriene receptors
Ligand-gated ion channel transport Linoleic acid (LA) metabolism
Lipid digestion, mobilization, and transport Lipoprotein metabolism
Localization of the PINCH-ILK-PARVIN complex to focal adhesions Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
Loss of Function of SMAD2/3 in Cancer Loss of Function of SMAD4 in Cancer
Loss of Function of TGFBR1 in Cancer Loss of Function of TGFBR2 in Cancer
Loss of Nlp from mitotic centrosomes Loss of proteins required for interphase microtubule organizationÿ from the centrosome
Lysine catabolism Lysosome Vesicle Biogenesis
Lysosphingolipid and LPA receptors M Phase
M/G1 Transition MAP kinase activation in TLR cascade
MAPK targets/ Nuclear events mediated by MAP kinases MASTL Facilitates Mitotic Progression
MEK activation MHC class II antigen presentation
MPS I - Hurler syndrome MPS II - Hunter syndrome
MPS IIIA - Sanfilippo syndrome A MPS IIIB - Sanfilippo syndrome B
MPS IIIC - Sanfilippo syndrome C MPS IIID - Sanfilippo syndrome D
MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B
MPS IX - Natowicz syndrome MPS VI - Maroteaux-Lamy syndrome
MPS VII - Sly syndrome MRN complex relocalizes to nuclear foci
Meiosis Meiotic recombination
Meiotic synapsis Membrane Trafficking
Membrane binding and targetting of GAG proteins Metabolism
Metabolism of Angiotensinogen to Angiotensins Metabolism of RNA
Metabolism of amino acids and derivatives Metabolism of carbohydrates
Metabolism of folate and pterines Metabolism of lipids and lipoproteins
Metabolism of mRNA Metabolism of nitric oxide
Metabolism of non-coding RNA Metabolism of nucleotides
Metabolism of polyamines Metabolism of porphyrins
Metabolism of proteins Metabolism of serotonin
Metabolism of steroid hormones and vitamin D Metabolism of vitamins and cofactors
Metabolism of water-soluble vitamins and cofactors Metal ion SLC transporters
Methionine salvage pathway Methylation
MicroRNA (miRNA) biogenesis Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Mineralocorticoid biosynthesis Minus-strand DNA synthesis
Miscellaneous substrates Mitochondrial ABC transporters
Mitochondrial Fatty Acid Beta-Oxidation Mitochondrial Uncoupling Proteins
Mitochondrial biogenesis Mitochondrial iron-sulfur cluster biogenesis
Mitochondrial protein import Mitochondrial tRNA aminoacylation
Mitochondrial transcription initiation Mitochondrial transcription termination
Mitotic Anaphase Mitotic G1-G1/S phases
Mitotic G2-G2/M phases Mitotic M-M/G1 phases
Mitotic Metaphase and Anaphase Mitotic Metaphase/Anaphase Transition
Mitotic Prometaphase Mitotic Prophase
Mitotic Spindle Checkpoint Mitotic Telophase/Cytokinesis
Molecules associated with elastic fibres Molybdenum cofactor biosynthesis
Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2 Mtb iron assimilation by chelation
Mucopolysaccharidoses Multifunctional anion exchangers
Muscarinic acetylcholine receptors Muscle contraction
MyD88 cascade initiated on plasma membrane MyD88 dependent cascade initiated on endosome
MyD88-independent cascade MyD88:Mal cascade initiated on plasma membrane
Myoclonic epilepsy of Lafora Myogenesis
N-Glycan antennae elongation N-glycan antennae elongation in the medial/trans-Golgi
N-glycan trimming and elongation in the cis-Golgi N-glycan trimming in the ER and Calnexin/Calreticulin cycle
NADE modulates death signalling NADPH regeneration
NCAM signaling for neurite out-growth NCAM1 interactions
NEP/NS2 Interacts with the Cellular Export Machinery NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
NF-kB is activated and signals survival NFG and proNGF binds to p75NTR
NGF processing NGF signalling via TRKA from the plasma membrane
NGF-independant TRKA activation NICD traffics to nucleus
NOD1/2 Signaling Pathway NOSIP mediated eNOS trafficking
NOSTRIN mediated eNOS trafficking NOTCH1 Intracellular Domain Regulates Transcription
NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH2 intracellular domain regulates transcription
NRAGE signals death through JNK NRIF signals cell death from the nucleus
NS1 Mediated Effects on Host Pathways Na+-dependent glucose transporters
Na+/Cl- dependent neurotransmitter transporters Nectin/Necl trans heterodimerization
Nef Mediated CD4 Down-regulation Nef Mediated CD8 Down-regulation
Nef and signal transduction Nef mediated downregulation of CD28 cell surface expression
Nef mediated downregulation of MHC class I complex cell surface expression Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
Negative epigenetic regulation of rRNA expression Negative regulation of FGFR signaling
Negative regulation of the PI3K/AKT network Negative regulators of RIG-I/MDA5 signaling
Nephrin interactions Netrin mediated repulsion signals
Netrin-1 signaling Neurofascin interactions
Neuronal System Neurophilin interactions with VEGF and VEGFR
Neurotoxicity of clostridi